Macular Degeneration News and Research

Latest Macular Degeneration News and Research

Multi-ethnic genome study unlocks new genetic links to health conditions

Research explores the genetic architecture of circulating metabolites, uncovering novel variant-metabolite associations and validating previous findings. It provides insights into the genetic contribution to metabolite levels and potential implications for human disease.

31 May 2023

Researchers use AI models to advance drug delivery system for chronic eye diseases

Wilmer Eye Institute, Johns Hopkins Medicine researchers say they have used artificial intelligence models and machine-learning algorithms to successfully predict which components of amino acids that make up therapeutic proteins are most likely to safely deliver therapeutic drugs to animal eye cells.

24 May 2023

New small-molecule drugs show potential clinical utility in treating world’s leading causes of blindness

In a University of California, Irvine-led study, researchers have discovered small-molecule drugs with potential clinical utility in the treatment of age-related macular degeneration (AMD), diabetic retinopathy (DR), and retinitis pigmentosa (RP).

9 May 2023

Scientists secure funding for cutting-edge research on age-related macular degeneration

A team of scientists led by a Northumbria University academic has won funding to research an eye disease suffered by over 190 million people worldwide.

5 Apr 2023

Membrane attack complex could be a potential therapeutic target to slow or prevent AMD

A study from the National Eye Institute (NEI) identified rare genetic variants that could point to one of the general mechanisms driving age-related macular degeneration (AMD), a common cause of vision loss in older adults.

3 Apr 2023

UTSW expert advises screening by 55 for people with family history of age-related macular degeneration

Patients with a family history of age-related macular degeneration (AMD), the leading cause of permanent vision loss in those older than 60, should visit an ophthalmologist by age 55 to be screened for signs of the disease, advises an expert at UT Southwestern Medical Center.

21 Mar 2023

UVA research provides new insight into common causes of vision loss

UVA Health scientists have discovered an unknown contributor to harmful blood vessel growth in the eye that could lead to new treatments for blinding macular degeneration and other common causes of vision loss.

24 Feb 2023

Study investigates anti-VEGF treatment for inflammatory eye disease in HTLV-1–infected ocular cells

A retrovirus known as human T-cell lymphotropic virus type 1 (HTLV-1) is known to cause a number of diseases, including inflammatory diseases of the eye. Recently, researchers in Japan have investigated an antibody treatment for inflammatory eye disease in ocular cells infected with HTLV-1.

21 Feb 2023

Researchers identify a new genetic risk factor for age-related macular degeneration

Researchers at Tel Aviv University identified a new genetic risk factor for the complex eye disease AMD (Age-related Macular Degeneration), a leading cause for loss of eyesight at an advanced age.

6 Feb 2023

Therapeutic small molecule can restore visual functions after optic nerve injury

Traumatic injury to the brain, spinal cord and optic nerve in the central nervous system (CNS) are the leading cause of disability and the second leading cause of death worldwide.

20 Jan 2023

Combination of multiple maps uncovers new genetic risk factor for AMD

Combining a map of gene regulatory sites with disease-associated loci has uncovered a new genetic risk factor of adult-onset macular degeneration (AMD), according to a new study publishing January 17th in the open access journal PLOS Biology by Ran Elkon and Ruth Ashery-Padan of Tel Aviv University, Israel, and colleagues.

18 Jan 2023

Do hPSC-derived retinal neurons possess intrinsic potential to form new synaptic connections after extraction from organoids?

Researchers successfully demonstrated that lab-grown retinal organoids made new synaptic connections, theoretically establishing their potential to treat blindness due to retinal degenerative diseases.

13 Jan 2023

Study: Two separate eye diseases may contribute to age-related macular degeneration

Two separate eye diseases may contribute to age-related macular degeneration (AMD), a leading cause of blindness in the United States, according to a new study from New York Eye and Ear Infirmary of Mount Sinai.

9 Jan 2023

History of obesity produces changes in innate immunity and neuroinflammation

A history of obesity caused by a high-fat diet produces changes in innate immunity that can promote inflammatory disease – changes that persist even after weight loss and a return to normal metabolism, according to a new study in mice.

5 Jan 2023

Research shows re-formation of synaptic connectivity in dissociated retinal organoids

Retinal cells grown from stem cells can reach out and connect with neighbors, according to a new study, completing a "handshake" that may show the cells are ready for trials in humans with degenerative eye disorders.

4 Jan 2023

Age-related macular degeneration reported to confer higher risk of severe SARS-CoV-2 infection

Recent evidence has emerged to suggest that age-related macular degeneration (AMD) is a clinical risk factor for increased risk for infection and mortality.

3 Jan 2023

Cellular models based on reprogrammed human cells could boost development of efficient therapies

Studies on diseases that affect the human brain are usually based on animal models which cannot reproduce the complexity of human neuropathies.

22 Dec 2022

NIH scientists use patient stem cells and 3D bioprinting to produce eye tissue

Scientists used patient stem cells and 3D bioprinting to produce eye tissue that will advance understanding of the mechanisms of blinding diseases.

22 Dec 2022

Long-lived Chilean rodent is a useful model of natural sporadic Alzheimer's Disease

Led by researchers from the University of California at Irvine, a new study reveals that a long-lived Chilean rodent, called Octodon degus (degu), is a useful and practical model of natural sporadic Alzheimer's Disease.

20 Dec 2022

Low ET levels in blood plasma may predict increased risk of cognitive impairment, dementia

A recent study by a team comprising researchers from the National University of Singapore and the National University Health System revealed that low levels of ergothioneine in blood plasma may predict an increased risk of cognitive impairment and dementia, suggesting possible therapeutic or early screening measures for cognitive impairment and dementia in the elderly.

19 Dec 2022

Macular Degeneration News and Research

Latest Macular Degeneration News and Research

Multi-ethnic genome study unlocks new genetic links to health conditions

Researchers use AI models to advance drug delivery system for chronic eye diseases

New small-molecule drugs show potential clinical utility in treating world’s leading causes of blindness

Scientists secure funding for cutting-edge research on age-related macular degeneration

Membrane attack complex could be a potential therapeutic target to slow or prevent AMD

UTSW expert advises screening by 55 for people with family history of age-related macular degeneration

UVA research provides new insight into common causes of vision loss

Study investigates anti-VEGF treatment for inflammatory eye disease in HTLV-1–infected ocular cells

Researchers identify a new genetic risk factor for age-related macular degeneration

Therapeutic small molecule can restore visual functions after optic nerve injury

Combination of multiple maps uncovers new genetic risk factor for AMD

Do hPSC-derived retinal neurons possess intrinsic potential to form new synaptic connections after extraction from organoids?

Study: Two separate eye diseases may contribute to age-related macular degeneration

History of obesity produces changes in innate immunity and neuroinflammation

Research shows re-formation of synaptic connectivity in dissociated retinal organoids

Age-related macular degeneration reported to confer higher risk of severe SARS-CoV-2 infection

Cellular models based on reprogrammed human cells could boost development of efficient therapies

NIH scientists use patient stem cells and 3D bioprinting to produce eye tissue

Long-lived Chilean rodent is a useful model of natural sporadic Alzheimer's Disease

Low ET levels in blood plasma may predict increased risk of cognitive impairment, dementia

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Macular Degeneration News and Research

Latest Macular Degeneration News and Research

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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