Macular Degeneration

Macular degeneration is a disease associated with aging that gradually destroys sharp, central vision. Central vision is needed for seeing objects clearly and for common daily tasks such as reading and driving.

What is Macular Degeneration?

This is also called age-related macular degeneration (AMD), as the major risk factor for this is aging. It is an eye disorder characterized by a number of conditions negatively affecting the macula.

What Causes Macular Degeneration?

Submacular Hemorrhage (SMH)

Retinal Drusen

Treatment of Submacular Hemorrhage

What is Age-Related Macular Degeneration?

Macular Degeneration Treatment

Macular Degeneration Symptoms

Latest Macular Degeneration News and Research

Buck Institute launches a new initiative to measure and extend human healthspan

The Buck Institute for Research on Aging today announced the launch of Healthspan Horizons, a new initiative designed to address one of the most urgent challenges in modern medicine: how to measure, understand, and extend healthspan-the years of life spent in good health.

6 Mar 2026

Building an affordable toolkit for healthy aging

As people age, they experience a gradual decline in intrinsic capacity (IC), the combined physical and mental abilities that support independence and health. The World Health Organization recognizes IC as a central indicator of resilience in aging, yet no affordable, validated tool exists to measure it.

27 Feb 2026

Smoking triggers epigenetic damage linked to macular degeneration

Through a series of experiments supported by the National Institutes of Health, Johns Hopkins Medicine (JHM) researchers say they have advanced understanding of how smoking damages the eye and contributes to the development of age-related macular degeneration (AMD), the leading worldwide cause of visual impairment and blindness among people 50 and older.

26 Feb 2026

Axol Bioscience acquires ophthalmology business from Newcells Biotech

Axol Bioscience Ltd. (Axol), a leading provider of induced pluripotent stem cell (iPSC) technologies for drug discovery and research, today announced that it has acquired the ophthalmology business of Newcells Biotech (Newcells), a leading drug discovery partner specializing in the development of in vitro models and bespoke assay services.

18 Feb 2026

Vitamin A and thyroid hormones in the retina shape fetal vision

Humans develop sharp vision during early fetal development thanks to an interplay between a vitamin A derivative and thyroid hormones in the retina, Johns Hopkins University scientists have found.

13 Feb 2026

New roadmap integrates aging into Parkinson disease models

Even though aging is the largest risk factor for Parkinson's disease, the majority of research aimed at taming the able neurodegenerativeincur motor disease has largely left aging out of the mix.

11 Feb 2026

Metformin linked to lower odds of intermediate macular degeneration in people with diabetes

A five-year image-based study in people with type 2 diabetes found metformin use was associated with lower odds of developing intermediate age-related macular degeneration. The observational findings suggest a potential protective link but do not establish causation and warrant prospective clinical trials.

4 Feb 2026

Everday diabetes medicine linked to less progression of age-related macular degeneration

Doctors have found that metformin, an everyday medicine for diabetes, is associated with less progression of age-related macular degeneration (AMD), the commonest cause of blindness in western countries.

3 Feb 2026

Ultra-thin nanotechnology enables safe wireless stimulation for retinal degeneration

An international research team led by Prof. Dr. Sedat Nizamoğlu from the Department of Electrical and Electronics Engineering at Koç University has developed a next-generation, safe, and wireless stimulation technology for retinal degenerative diseases that cause vision loss.

23 Jan 2026

Silent thief of sight: Rutgers Health experts highlight glaucoma risks, early detection

January is Glaucoma Awareness Month, prompting Rutgers Health experts to underscore the importance of early detection and public awareness.

14 Jan 2026

Cardiovascular risk scores predict future development of serious eye diseases

A new study from UCLA Health shows that a cardiovascular risk score already used routinely in primary care can predict who will develop serious eye diseases years later.

7 Jan 2026

Research breakthrough could provide a new, non-invasive way to assess retinal health

For the first time, an international research team led by Nanyang Technological University, Singapore (NTU Singapore) has recorded a tiny mechanical "twitch" in living human and rodent eyes at the exact moment a rod photoreceptor detects light.

7 Jan 2026

Greenland shark eyesight offers clues to longevity, vision, and healthy aging

Dorota Skowronska-Krawczyk sits in her office, eyes fixed on the computer monitor in front of her.

5 Jan 2026

People with central vision loss can accurately judge approaching vehicles

People with central vision loss can judge the motion of vehicles almost as accurately as people with normal vision, a new international study shows.

19 Dec 2025

New clinical trial offers hope for patients with advanced “dry” age-related macular degeneration

Age-related macular degeneration, the leading cause of vision loss and blindness for Americans 65 and older, is a progressive disease affecting central vision.

17 Dec 2025

Australian researchers pinpoint specific genetic changes linked to severe AMD

Australian researchers have for the first time pinpointed specific genetic changes that increase the risk of severe, sight-threatening forms of age-related macular degeneration (AMD).

9 Dec 2025

Study reveals new genetic insights into reticular pseudodrusen in people with AMD

A study funded in part by the National Institutes of Health (NIH) has revealed important insights into the genetics of deposits in the eye, known as reticular pseudodrusen (RPD), that are linked to greater risk of vision loss among people with age-related macular degeneration (AMD).

8 Dec 2025

Eli Lilly’s Adverum move: The future of ocular gene therapy at the 4th Ophthalmic Drug Delivery Summit

The race to develop safer, longer lasting, and less invasive treatments is accelerating, and at the heart of that challenge lies drug delivery.

From Hanson Wade Group - 4th Ophthalmic Drug Delivery Summit 26 Nov 2025

Inflammation control can protect against AMD-like retinal damage

University of Minnesota Medical School researchers have shown that reducing chronic inflammation can significantly protect against age-related macular degeneration (AMD)-like pathology in preclinical models.

21 Nov 2025

Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory

Replacing APOE4 with APOE2 in adult mice rapidly reshapes brain lipids and gene expression, even after development is complete. This switch, especially when targeted to astrocytes, reduces amyloid burden, dampens gliosis, and improves associative memory despite E2-like peripheral lipid risks.

12 Nov 2025