Macular Degeneration

Macular degeneration is a disease associated with aging that gradually destroys sharp, central vision. Central vision is needed for seeing objects clearly and for common daily tasks such as reading and driving.

What is Macular Degeneration?

This is also called age-related macular degeneration (AMD), as the major risk factor for this is aging. It is an eye disorder characterized by a number of conditions negatively affecting the macula.

What is Age-Related Macular Degeneration?

Macular Degeneration Symptoms

What Causes Macular Degeneration?

Macular Degeneration Treatment

Submacular Hemorrhage (SMH)

Treatment of Submacular Hemorrhage

Retinal Drusen

Latest Macular Degeneration News and Research

New chip restores reading ability for macular degeneration patients

A tiny wireless chip implanted in the back of the eye and a pair of high-tech glasses have partially restored vision to people with an advanced form of age-related macular degeneration. In a clinical trial led by Stanford Medicine researchers and international collaborators, 27 out of 32 participants had regained the ability to read a year after receiving the device.

21 Oct 2025

Prima implant offers new hope for vision restoration in atrophic AMD

Age-related macular degeneration (AMD) causes progressive vision loss in many elderly people, and no treatment is available for the so-called atrophic form of the disease.

20 Oct 2025

Live retinal imaging uncovers early signs of diabetic eye disease

A new method of taking microscopic images of a live mouse's retina through the eye allows to record the reaction of brain cells to disease and treatment.

6 Oct 2025

Genetic risk scores fail to predict survival after diagnosis

Research indicates that disease susceptibility genetics poorly predict survival, while longevity PGSs offer stronger associations with post-diagnosis mortality.

2 Oct 2025

New intramuscular mRNA vaccine offers easier alternative to treat neovascular eye diseases

An mRNA vaccine developed by researchers from Japan suppressed abnormal blood vessel growth or neovascularization in the retina of mouse models.

26 Sep 2025

Reversing age-related vision loss with retinal lipid therapy

Changes in vision are often a common sign of aging. If you sit in a dimly lit restaurant with anyone over the age of 60, you'll likely hear the person say, "Hold on - let me pull out my cell phone. I need more light to read the menu!" But what if we could reverse age-related visual decline?

24 Sep 2025

New eyedrop raises hopes for less invasive treatment of serious vision conditions

A new eyedrop has shown early success in delivering protective compounds to where they're needed most in the eye, raising hopes for less invasive treatment of serious vision conditions.

22 Sep 2025

New research aims to use eyedrops to lower lifetime risk of nearsightedness complications

For the first time, researchers are leading a national study to see if the onset of nearsightedness can be delayed – and consequently reduced in magnitude over a lifetime – with the use of eyedrops in young children.

19 Sep 2025

Psoriasis linked to higher risk of age-related macular degeneration

New research presented today at the European Academy of Dermatology and Venereology (EADV) Congress 2025 reveals that people with psoriasis face a significantly increased risk of developing age-related macular degeneration (AMD), a leading cause of vision loss.

17 Sep 2025

Study uncovers new associations between gut microbiome and aging process

A new research paper was published in Volume 17, Issue 8 of Aging-US on August 1, 2025, titled "Causal relationships between gut microbiome and hundreds of age-related traits: evidence of a replicable effect on ApoM protein levels."

10 Sep 2025

Heparanase 2 emerges as key protector of blood vessel integrity

An international research team led by MDI Biological Laboratory President Hermann Haller, M.D. and postdoctoral researcher Yannic Becker, Ph.D. has discovered that a little-known molecule, heparanase 2 (Hpa2), plays a critical role in maintaining blood vessels' integrity.

2 Sep 2025

Alzheimer’s research uncovers a new therapeutic pathway for the memory-robbing malady

The gut contains the largest collection of immune cells in the body. New research at the Buck Institute shows that some of those immune cells travel along the brain/gut axis in a mouse model of Alzheimer's disease (AD) providing a potential new therapeutic pathway for the memory-robbing malady.

29 Aug 2025

Omega-3 rich diet linked to lower risk of childhood myopia

A diet rich in omega-3 fatty acids, found predominantly in fish oils, may help ward off the development of short sightedness (myopia) in children, while a high intake of saturated fats, found in foods such as butter, palm oil, and red meat, may boost the risk of the condition, finds research published online in the British Journal of Ophthalmology.

20 Aug 2025

Early puberty and childbirth tied to accelerated aging and higher disease risk

Reproductive timing matters when it comes to aging and age-related disease. In a study now online at eLife¸ Buck researchers determine that girls who go through puberty (the onset of menstruation) before the age of 11 or women who give birth before the age of 21 have double the risk of developing type 2 diabetes, heart failure and obesity and quadruple the risk of developing severe metabolic disorders.

18 Aug 2025

New AAV gene therapy reverses age-related macular degeneration

Neovascular age-related macular degeneration (nAMD) is a progressive eye disease characterized by choroidal neovascularization and subretinal hemorrhage and exudation, leading to vision impairment. Current first-line treatment for nAMD are anti-VEGF agents, which has shown promising therapeutics outcomes.

18 Aug 2025