Macular Degeneration News and Research

Latest Macular Degeneration News and Research

CFH Y402H confers similar risk of soft drusen and both forms of advanced AMD

Gene is associated with increased risk of precursor of macular degeneration A variant in a gene called Complement Factor H (CFH) appears to contribute to the increased risk of advanced age-related macular degeneration (AMD) largely or entirely through its impact on the development of a precursor of advanced AMD called soft drusen (small yellowish, extracellular deposits of lipid, protein and cellular debris in the back of the eye), according to a multinational team of researchers.

2 Dec 2005

Chlamydia pneumoniae may cause vision problems

Researchers at the Massachusetts Eye and Ear Infirmary (MEEI) have found that Chlamydia pneumoniae, a bacterium linked to heart disease and capable of causing chronic inflammation, was present in the diseased eye tissue of five out of nine people with neovascular, or "wet," age-related macular degeneration (AMD).

7 Nov 2005

Smokers twice as likely to lose their sight - calls for warnings on cigarette packets

Experts are warning smokers that they are twice as likely as non-smokers to lose their sight in later life.

10 Sep 2005

Researchers have discovered a gene linked to age-related maculopathy

University of Pittsburgh researchers have discovered a gene linked to age-related maculopathy (ARM), the leading cause of untreatable blindness in the elderly. Their discovery suggests a simple test might be able to identify those at risk for what is commonly known as macular degeneration (AMD) and may lead to the development of more effective preventive strategies.

16 Aug 2005

New way to prevent macular degeneration

Two studies from an unusual research partnership at the University of Chicago appear to have resolved a long-standing dispute about the role of melanin in the eye. The studies, one published in the Proceedings of the National Academy of Sciences (PNAS) and one early online in the Journal of the American Chemical Society (JACS), also suggest a new way to prevent a common cause of blindness.

28 Jul 2005

New insight into age-related macular degeneration

Age-related macular degeneration is the leading cause of blindness in older adults, yet researchers are still in the dark about many of the factors that cause this incurable disease.

25 Jul 2005

Sirna Therapeutics granted new UK patents

Sirna Therapeutics has announced that the United Kingdom (UK) Patent Office has granted the Company two additional short interfering RNA (siRNA) target patents. The first patent covers any siRNA with one or more chemical modifications targeting Vascular Endothelial Growth Factor (VEGF).

12 Jul 2005

New generation of lenses makes evolutionary leap in eliminating need for glasses

The need for reading glasses or bifocals as we age may begin fading from sight with the latest generation of intraocular lenses.

3 Jun 2005

New approach to inhibiting blood vessel growth or angiogenesis

A manmade protein with a tail of amino acids delivered to target cells can dramatically reduce blood vessel growth that obstructs vision or feeds a tumor, researchers have found.

31 May 2005

Pharmaceutical industry faces multiple challenges - future lies in drug pipeline sustainability

High clinical development costs coupled with declining drug discovery success rates are causing productivity levels to fall in the global pharmaceuticals industry. The imminent patent expiry of several major blockbuster drugs and the related rise of cheaper generic alternatives is further exacerbating the situation.

25 May 2005

New treatment improves visual acuity score of patients with retinitis pigmentosa

Neurotech SA announced positive results from an open-label Phase I clinical trial (03-EI-0234) of its lead product, NT-501. NT-501 uses Neurotech’s patented Encapsulated Cell Technology (ECT) as a device to deliver ciliary neurotrophic factor (CNTF) to eyes of visually impaired patients with retinitis pigmentosa (RP). Neurotech is a biotechnology company specializing in the development of novel therapeutics to treat diseases of the eye. The company is headquartered in Paris.

8 May 2005

Researchers present information on artificial retina

Researchers from the University of Southern California and the Doheny Eye Institute will be presenting data on the first six patients implanted with an intraocular retinal prosthesis-more popularly referred to as an artificial retina-developed and manufactured in partnership with Second Sight Medical Products, of Sylmar, Calif.

2 May 2005

Vitamins E and C confirmed safe at high doses

Fourteen leading safety and antioxidant experts reviewed the available scientific literature on vitamins E and C and concluded vitamin E is safe for the general population at intakes up to 1600 IU daily and vitamin C is safe at up to 2000 mg daily, according to a new article published in the April issue of the American Journal of Clinical Nutrition (AJCN).

2 May 2005

Solar cell implant may restore some sight for the blind

Ophthalmologists at Rush University Medical Center implanted Artificial Silicon Retina (ASR) microchips in the eyes of five patients to treat vision loss caused by retinitis pigmentosa (RP). The implant is a silicon microchip 2mm in diameter and one-thousandth of an inch thick, less than the thickness of a human hair.

1 May 2005

Age-related macular degeneration is triggered, possibly by an infection

Age-related macular degeneration, the leading cause of blindness in the elderly, occurs when a common inherited gene variation is triggered, possibly by an infection, according to a new study led by researchers at Columbia University Medical Center and the University of Iowa, with an international research team.

1 May 2005

Research offers hope for treatment of age-related blindness

Rheumatoid arthritis patients treated with anti-inflammatory drugs are 10 times less likely to develop age-related macular degeneration (AMD), the most common form of blindness in people over 55, researchers at the University of British Columbia and University of Saskatchewan have found.

27 Apr 2005

Smoking doubles the risk of macular degeneration

Smoking doubles the risk of the progressive and irreversible eye condition, macular degeneration, and may account for almost 30,000 cases in the UK, suggests research in the British Journal of Ophthalmology.

19 Apr 2005

Bionic eyes from Stanford

Stanford physicists and eye doctors have teamed up to design a "bionic eye," of sorts. On Feb. 22 in the Journal of Neural Engineering, Daniel Palanker, Alexander Vankov and Phil Huie from the Department of Ophthalmology and the Hansen Experimental Physics Laboratory and Stephen Baccus from the Department of Neurobiology published a design of an optoelectronic retinal prosthesis system that can stimulate the retina with resolution corresponding to a visual acuity of 20/80

4 Apr 2005

Research tool for turning off genes may eventually have therapeutic application

A research team based at Massachusetts General Hospital (MGH) has identified 80 new genes essential to the process of RNA interference (RNAi), a powerful new research tool for inactivating genes in plants or animals.

28 Mar 2005

Compound found in broccoli is a powerful disease fighter

More than 300 scientific studies point to an antioxidant found in broccoli sprouts, sulforaphane glucosinolate (SGS), as a factor in preventing multiple diseases, including several types of cancer, high blood pressure, macular degeneration and stomach ulcers.

21 Mar 2005