Male Infertility

Male infertility is on the rise in society. Approximately 15% of married couples have trouble conceiving despite having regular unprotected sex for more than a year. Out of the couples who are in their thirties, only 30% are able to conceive within the first three months; the rest have trouble due to male infertility issues.

Causes of Male Infertility

Infertility is a reproductive system disorder which results in the inability of a couple to procreate. The reasons for not being able to conceive can be varied and could be related to either partner. When the reproductive system of the male has a problem which makes it difficult for the couple to have a child, it is termed male infertility.

Sperm Production Problems

Erection and Ejaculation Problems

Blockage of Sperm Transport

Preventing Male Infertility

Male Infertility Research

Male Infertility Epidemiology

How is Male Infertility Diagnosed?

Fertility and Age

Low Sperm Count

Causes of a Low Sperm Count

Testing for a Low Sperm Count

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Intracytoplasmic Sperm Injection (ICSI)

Latest Male Infertility News and Research

New genetic mechanism that can cause severe male infertility identified

Scientists at Newcastle University have identified a new genetic mechanism that can cause severe forms of male infertility.

10 Jan 2022

Impact of SARS-CoV-2 infection on human semen quality

A new review article aimed to extract, review and summarize these articles from the mentioned databases to determine the link between SARS-CoV-2 infection and semen quality.

3 Nov 2021

Researchers identify γ-tubulin ring complex to be responsible for providing centriole stability

Centrioles are cylindrical structures involved in the generation of microtubules-;fibers inside of cells that form a network to provide structure and shape to cells and to mediate transport processes.

1 Nov 2021

Scientists flip a new piece in the male infertility puzzle

Scientists at Cincinnati Children's appear to have flipped another piece in the underexplored puzzle of male infertility.

27 Oct 2021

UGA study makes breakthrough for treatment of male infertility

With global rates of male infertility continuing to rise, a new study in spermatogonial stem cell research led by researchers at the University of Georgia provides hope for future clinical therapies.

19 Oct 2021

New approach reveals ‘protein partners’ that may contribute to unusual pathologies of COVID-19

COVID-19 not only causes symptoms characteristic of a typical respiratory disorder, but has also been known to trigger a wide range of other symptoms in people who had been infected, some lasting even long after individuals test negative for the virus.

30 Sep 2021

New NIH-funded research to solve the male infertility and spermatogenesis puzzle

Male infertility is on the rise, with significant declines in sperm quantity and quality occurring across the human population worldwide in the past two decades.

16 Sep 2021

Tumor-related risk factors affect conversion of active surveillance to treatment for prostate cancer

For men with "low-risk" prostate cancer initially managed with active surveillance, cancer-related factors such as tumor grade and size are key risk factors for conversion to active treatment, reports a study in The Journal of Urology®, an Official Journal of the American Urological Association.

10 Sep 2021

Researchers discover molecule that plays an important role in sperm motility regulation

About 120 million unintended pregnancies occurred each year between 2015 and 2019 worldwide. While there are oral contraceptives for women, the development of oral contraceptives for men has not been successful.

24 Aug 2021

Study provides new data on discontinuation of active surveillance by low-risk prostate cancer patients

Nearly half of men initially managed with active surveillance for "low-risk" prostate cancer transition to definitive treatment – such as surgery or radiation therapy – within a few years after diagnosis.

23 Aug 2021

Researchers identify key protein that plays an essential role in male fertility

Mammalian sperm cannot fertilize an egg from the get-go. It's an ability acquired only after insemination, during passage through the female reproductive tract, and requires two consecutive, time-sensitive processes to provide sperm with the physical and biochemical traits necessary to complete their fundamental job.

20 Aug 2021

Study reveals mechanism behind male infertility caused by autoimmune disease

Investigators have found that the absence of autoimmune regulator (Aire) in mice results in fertility problems similar to those affecting men with autoimmune polyendocrine syndrome type I (APS-1).

19 Aug 2021

Mutation in a single gene may be responsible for non-obstructive azoospermia in men

Mutation in a single gene appears to account for a form of male infertility in which men fail to produce sperm, according to an international study funded in part by the National Institutes of Health.

5 Aug 2021

Discovery opens door to new diagnostics and therapeutic strategies for male infertility

Scientists at The University of Toledo discovered new movement in sperm that provides innovative avenues for diagnostics and therapeutic strategies for male infertility.

28 Jun 2021

New method successfully reversed male infertility in mice

The ability of stem cells to fix impaired functions of host tissues after transplantation has been a lifesaving breakthrough in treating previously incurable conditions. Much like a coin toss, however, the fate of the transplanted stem cells is unpredictable. They may choose self-renewal, grow into a different kind of tissue, or die.

8 Jun 2021

New device can increase penile length and preserve erectile function in men after prostatectomy

A new type of penile traction therapy (PTT) device can increase penile length and preserve erectile function in men who have undergone prostate cancer surgery (prostatectomy), reports a clinical trial in The Journal of Urology®, Official Journal of the American Urological Association (AUA).

1 Jun 2021

Novel protein interactions with ACE2 disrupted by SARS-CoV-2, contributes to COVID-19 pathologies

A severe and often fatal immune response called a “cytokine storm” can occur following SARS-CoV-2 infection. Some patients suffer from a range of complications several months after testing negative for SARS-CoV-2, and this is called ‘Long Haul’ or ‘Long’ COVID-19. The causes behind this phenomenon are not well understood.

31 May 2021

New focus on adverse impact of male factors in assisted reproductive treatments

The adverse impact of male factors in assisted reproductive treatments was brought into a clear and disturbing focus at the 10th Congress of the Asia Pacific Initiative on Reproduction.

17 May 2021

Patient satisfaction scores vary by insurance status, shows urology clinic data

For patients seen at a urology clinic, patient satisfaction scores vary by insurance status - with higher scores for patients on Medicare and commercial insurance, but lower scores for those on Medicaid, reports a study in Urology Practice®, an Official Journal of the American Urological Association (AUA).

12 May 2021

Automated machine learning predicts male infertility based on Johnsen score

Infertility affects females and males equally. In male infertility, azoospermia (a medical condition with no sperm in semen) is a major problem that prevents a couple from having a child.

11 May 2021