Male Infertility

Male infertility is on the rise in society. Approximately 15% of married couples have trouble conceiving despite having regular unprotected sex for more than a year. Out of the couples who are in their thirties, only 30% are able to conceive within the first three months; the rest have trouble due to male infertility issues.

Causes of Male Infertility

Infertility is a reproductive system disorder which results in the inability of a couple to procreate. The reasons for not being able to conceive can be varied and could be related to either partner. When the reproductive system of the male has a problem which makes it difficult for the couple to have a child, it is termed male infertility.

Sperm Production Problems

Erection and Ejaculation Problems

Blockage of Sperm Transport

Preventing Male Infertility

Male Infertility Research

Male Infertility Epidemiology

How is Male Infertility Diagnosed?

Fertility and Age

Low Sperm Count

Causes of a Low Sperm Count

Testing for a Low Sperm Count

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Intracytoplasmic Sperm Injection (ICSI)

Latest Male Infertility News and Research

Sucralose disrupts male fertility by damaging sperm and altering hormones in animal study

Researchers found that chronic sucralose exposure in male rats disrupted reproductive hormones, damaged sperm, and impaired testicular function through oxidative stress and autophagy dysregulation. These findings raise concerns about the reproductive risks of high sucralose intake and its persistent presence in the environment.

19 May 2025

Low phosphate levels may help explain male infertility, study finds

Men with fertility problems were significantly more likely to have low blood phosphate levels, a mineral essential for energy and reproductive function. Researchers found lower phosphate was linked to poorer sperm motility, suggesting a possible pathway for new fertility treatments.

10 May 2025

Heat triggers sperm activation for fertilization in mammals

In mammals - including us humans - sperm are surprisingly picky about temperature, thriving best in conditions a few degrees cooler than normal body temperature.

2 May 2025

COVID-19 lowers sperm count and motility, new study confirms

SARS-CoV-2 infection is linked to significant declines in sperm quality, including reduced sperm count, motility, and increased DNA fragmentation, as shown in both cross-sectional and longitudinal observations.

24 Apr 2025

New discovery shows piRNA's adaptive role in silencing jumping genes

Adverse genetic mutations can cause harm and are due to various circumstances. "Jumping genes" are one cause of mutations, but cells try and combat them with a specialized RNA called piRNA.

20 Mar 2025

Low semen quality linked to shorter lifespan

Researchers determine how low semen quality may impact mortality risk.

10 Mar 2025

Semen quality linked to longevity in men

Men's semen quality is associated with how long they live according to a study of nearly 80,000 men, which is published today (Wednesday) in Human Reproduction, one of the world's leading reproductive medicine journals.

4 Mar 2025

Study unveils protein complex critical for sperm morphology

The human body is full of checks and balances that ensure correct growth, development, and function of all our different systems. Now, researchers from Japan have reported a newly discovered protein interaction that regulates sperm development.

3 Mar 2025

Can red ginseng prevent diabetes? New research uncovers its potential

Red ginseng extract powder significantly improved glycemic control in prediabetic Korean adults over 12 weeks without adverse effects. The findings suggest its potential role in diabetes prevention, though larger studies are needed.

23 Feb 2025

Crick researchers identify key Y chromosome genes influencing sperm development

Researchers at the Crick have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice.

23 Jan 2025

Study unveils role of TLE6 in male sperm development

Infertility is a major global challenge associated with physiological and psychological impact. Genetic mutations that affect early embryonic development, oocyte (egg cell) maturation, and fertilization have recently been studied as causes of infertility.

16 Jan 2025

Could mulberry extract be the key to fighting obesity-induced reproductive dysfunction?

Research indicates mulberry extract's efficacy in addressing obesity-related male infertility, enhancing reproductive outcomes through bioactive compounds.

16 Jan 2025

Genetic insights into reproductive health and longevity

Led by researchers from the University of Oxford's Leverhulme Centre for Demographic Science and the University of Iceland, the review explores how genetic variations can explain differences in reproductive health and longevity.

14 Dec 2024

How alcohol impacts male health

This research explores how alcohol consumption disrupts metabolism, damages the liver, and impairs male reproductive health, emphasizing the complex mechanisms and public health implications.

18 Nov 2024

How carnitine transporters boost reproductive health

Research uncovers the critical role of carnitine transporters in maintaining fertility by regulating energy metabolism and protecting reproductive cells from oxidative stress. It suggests new pathways for treating infertility through carnitine supplementation and targeted therapies.

6 Oct 2024