Metabolism News and Research

Latest Metabolism News and Research

Study reveals how bone cells form dendrites that are important for maintaining bone strength

Embedded within bone tissue are osteocytes, cells with tree-like projections called dendrites that are important for receiving communication from other cells.

1 Nov 2021

Researchers generate and characterize the hepatic organoid culture system

Organoid technologies have become a powerful emerging tool to model liver diseases, for drug screening, and for personalized treatments.

1 Nov 2021

Alteration in gut microbiome may lead to hyperinflammation in severe COVID-19

A team of international scientists has recently identified a distinct set of proinflammatory mediators and metabolites associated with the fatal consequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Moreover, they have established a link between gut microbiome alteration and hyper-inflammatory response in patients with severe COVID-19. The study is currently available on the bioRxiv* preprint server.

1 Nov 2021

Researchers decipher when and why T cells become non-responsive to immunotherapy

Non-small cell lung cancer is the most common type of lung cancer in humans. Some patients with NSCLC receive a therapy called immune checkpoint blockade (ICB) that helps kill cancer cells by reinvigorating a subset of immune cells called T cells, which are "exhausted" and have stopped working.

30 Oct 2021

Researchers discover potential new Covid-19 treatment

Researchers have identified a potential new treatment that suppresses the replication of SARS-CoV-2, the coronavirus that causes Covid-19.

30 Oct 2021

Brown fat could be the key to healthy metabolism in obese people

Not all forms are obesity are the same and brown fat could make all the difference. A study led by Florian Kiefer's research group from the Division of Endocrinology and Metabolism of the Department of Medicine III at MedUni Vienna and Vienna General Hospital shows that people who are seriously overweight (obese) who also have active brown fat have a healthier metabolism and use more energy than obese people without brown fat.

29 Oct 2021

UT Southwestern study suggests potential way to prevent Alzheimer’s disease

A study by UT Southwestern researchers finds that changing the biochemistry of parts of brain cells abolished the formation of amyloid beta plaques in a mouse model of Alzheimer's disease.

29 Oct 2021

Study of "dented" internal clocks reveals why shift workers gain weight and develop diabetes

A study of "dented" internal clocks seems to have provided evidence for a theory as to why people who work late or irregular hours are susceptible to weight gain and diabetes.

28 Oct 2021

A novel approach to improve the stability of Remdesivir

A recent study discusses a novel method to enhance the stability of Remdesivir.

28 Oct 2021

Chlorophyll catabolite pheophorbide A shows potential against SARS-CoV-2

A new study identifies a potent SARS-CoV-2 antiviral, Pheophorbide a (PheoA), which is a compound derived from the plant Marchantia polymorpha L.

27 Oct 2021

Modulating glycogen metabolism in fat cells may offer new approaches for weight loss

Humans carry around with them, often abundantly so, at least two kinds of fat tissue: white and brown. White fat cells are essentially inert containers for energy stored in the form of a single large, oily droplet.

27 Oct 2021

Taking lessons in molecular therapeutics from earthworms to combat COVID

Scientists were interested in further investigating the defense mechanism of earthworms in an effort to discover therapeutic solutions against SARS-CoV-2.

27 Oct 2021

Research reveals the microbial landscape of patients with systemic lupus erythematosus

Systemic lupus erythematosis (SLE) is an autoimmune disease in which the immune system targets tissues of the body, causing widespread inflammation and affecting multiple organs such as the kidney and the brain.

27 Oct 2021

Polyphenol-rich diet improves the intestinal permeability in older adults

The increase of intestinal permeability is associated with factors such as ageing, food allergies and intolerances and unhealthy diets.

26 Oct 2021

Study identifies how cancer cells transform macrophages into supporters of their growth

A Ludwig Cancer Research study has identified a means by which cancer cells engineer the conversion of immune cells known as macrophages from destroyers of tumors to supporters of their growth and survival.

26 Oct 2021

Study provides a specific target to tackle breast cancer relapse

Molecular targets for therapies that could prevent breast cancer recurrence have been identified by a group of German, Norwegian and British scientists who analyzed tumour cells that proved resistant to the original treatment.

25 Oct 2021

Scientists show how cold could alleviate multiple sclerosis symptoms

In evolutionary biology, the "Life History Theory", first proposed in the 1950s, postulates that when the environment is favorable, the resources used by any organism are devoted for growth and reproduction.

25 Oct 2021

Researchers identify a common gene variant that drives the efficiency and outcome of dialysis

Every day, the human kidneys clean about 1,500 liters of blood by producing approximately 1–2 liters of urine. Thereby, the body gets rid of excess water and toxic waste products of the metabolism or also drugs and maintains the balance of water and minerals in the tissues.

21 Oct 2021

Skeletal muscle in individuals with type 2 diabetes has a different circadian rhythm, research shows

Almost all cells regulate their biological processes over a 24-hour period, otherwise called a cell's circadian rhythm. To do so, cells use a biological clock that cycles different genes on and off throughout the day and night. Scientists already know that our metabolic health can suffer when our biological clock breaks down, due to shift work or sleep disorders, for example. However, it's unclear how exactly the biological clock of people with type 2 diabetes differs from healthy people.

21 Oct 2021

U-M researchers target a protein channel in the cell’s lysosome to selectively kill cancer cells

Cancer treatments necessarily target unchecked cell growth, and selectively kill cancer cells while sparing normal cells and avoiding general toxicity in the human body.

20 Oct 2021

Metabolism News and Research

Latest Metabolism News and Research

Study reveals how bone cells form dendrites that are important for maintaining bone strength

Researchers generate and characterize the hepatic organoid culture system

Alteration in gut microbiome may lead to hyperinflammation in severe COVID-19

Researchers decipher when and why T cells become non-responsive to immunotherapy

Researchers discover potential new Covid-19 treatment

Brown fat could be the key to healthy metabolism in obese people

UT Southwestern study suggests potential way to prevent Alzheimer’s disease

Study of "dented" internal clocks reveals why shift workers gain weight and develop diabetes

A novel approach to improve the stability of Remdesivir

Chlorophyll catabolite pheophorbide A shows potential against SARS-CoV-2

Modulating glycogen metabolism in fat cells may offer new approaches for weight loss

Taking lessons in molecular therapeutics from earthworms to combat COVID

Research reveals the microbial landscape of patients with systemic lupus erythematosus

Polyphenol-rich diet improves the intestinal permeability in older adults

Study identifies how cancer cells transform macrophages into supporters of their growth

Study provides a specific target to tackle breast cancer relapse

Scientists show how cold could alleviate multiple sclerosis symptoms

Researchers identify a common gene variant that drives the efficiency and outcome of dialysis

Skeletal muscle in individuals with type 2 diabetes has a different circadian rhythm, research shows

U-M researchers target a protein channel in the cell’s lysosome to selectively kill cancer cells

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting