Metabolism News and Research

Latest Metabolism News and Research

Excessive fructose consumption can result in non-alcoholic fatty liver disease

Excessive consumption of fructose - a sweetener ubiquitous in the American diet - can result in non-alcoholic fatty liver disease (NAFLD), which is comparably abundant in the United States.

24 Aug 2020

RNA-targeting compound restarts a healing factor silenced by heart attack

A heart attack can leave parts of the heart permanently scarred and stiff, resulting in prolonged disability and potential progression toward heart failure. Scientists have studied various ways to repair or regenerate such damaged heart tissue, with limited success.

24 Aug 2020

$Prolonged use of bisphosphonates increases risk of atypical femur fractures$

Prolonged use of bisphosphonates increases risk of atypical femur fractures

The risk of atypical femur fractures increases with prolonged use of bisphosphonates, drugs commonly used to treat osteoporosis, according to a new study.

24 Aug 2020

Congenital disorder of fat metabolism can cause chronic hyperreaction of the immune system

Scientists at the University of Bonn identify previously unknown disease mechanism. A congenital disorder of the fat metabolism can apparently cause chronic hyperreaction of the immune system.

24 Aug 2020

Study: Frequent use of antimicrobial drugs impairs bacterial diversity in saliva

The strongest associations were presented with azithromycin that is used for example to middle ear infections, strep throat and pneumonia.

24 Aug 2020

Developing more precise, targeted therapy for a highly aggressive breast cancer

Taking advantage of a cancer cell's altered metabolism that drives its runaway growth, Princess Margaret researchers are zeroing in on these molecular changes to help them develop more precise drug targets for one of the most deadly breast cancers.

21 Aug 2020

Dusp8 protein has regulatory effects on hypothalamic insulin sensitivity

The brain plays a major role in controlling our blood glucose levels. In type 2 diabetics this glucose metabolism brain control is often dysfunctional. Genetic components for this phenomenon have so far remained elusive.

21 Aug 2020

Study could reveal brain cells and circuits that influence human health and metabolism in response to dietary changes

A new federally funded study could reveal the nervous system cells and circuits in our brains that influence our metabolism and health in response to dietary changes.

21 Aug 2020

Macaques show low neutralizing antibody and cellular immune response to SARS-CoV-2

A new study published on the preprint server bioRxiv* in August 2020 presents a cynomolgus macaque model that develops symptomatic SARS-CoV-2 infection in a mild form, with low or no antibody responses, making it suitable to study human responses to vaccines and drugs targeting the virus.

21 Aug 2020

Bioinformatics identifies key genes and cellular pathways in COVID-19

The COVID-19 pandemic is showing no signs of waning or extinction anytime soon. Now, a new study published on the preprint server bioRxiv* in August 2020 shows a new bioinformatics approach to studying the pathogenesis of this disease, by uncovering the differentially expressed genes (DEGs) and cell signaling pathways that cause the disease characteristics. This will help develop better therapies to counter the effects of these genes.

20 Aug 2020

Study examines the effect of low-carbohydrate, high-fat diet on older adults

A new study, published in Nutrition and Metabolism, from researchers with the University of Alabama at Birmingham's Nutrition Obesity Research Center observed improvements in body composition, fat distribution and metabolic health in response to an eight-week, very low-carbohydrate diet.

20 Aug 2020

A metabolic enzyme shows great potential as target for immunotherapies

The metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system.

20 Aug 2020

Air pollution may play a role in development of cardiometabolic diseases, shows study

Air pollution is the world's leading environmental risk factor, and causes more than nine million deaths per year.

20 Aug 2020

Study reveals a promising treatment for Parkinson's disease

Scientists at the University Bath in the UK have discovered a series of protein structures that are thought to be highly relevant to the onset of Parkinson's disease.

20 Aug 2020

Girls with anorexia nervosa can have stunted growth

Girls with anorexia nervosa can have stunted growth and may not reach their full height potential, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

20 Aug 2020

Gastric bypass surgery is the most effective therapy to treat type 2 diabetes

Gastric bypass surgery is the most effective therapy to treat or reverse type 2 diabetes in severely obese patients.

20 Aug 2020

Study may lead to new targeted therapies that inhibit the spread of cancer

For decades, physicians have known that many kinds of cancer cells often spread first to lymph nodes before traveling to distant organs through the bloodstream.

20 Aug 2020

Study sheds light on 500-year old mystery about the human heart

Researchers have investigated the function of a complex mesh of muscle fibres that line the inner surface of the heart. The study, published in the journal Nature, sheds light on questions asked by Leonardo da Vinci 500 years ago, and shows how the shape of these muscles impacts heart performance and heart failure.

19 Aug 2020

Study: Vitamin D supplementation is associated with compositional changes in a baby's microbiome

New research from the CHILD Cohort Study has shed light on the influence of vitamin D supplementation on a baby's developing gut microbiome.

19 Aug 2020

Diabetes-related complications increase with elevated levels of heart failure marker

Healthy people - especially women - with elevated levels of the heart failure marker NT-proBNP have a lower risk of developing type 2 diabetes.

18 Aug 2020

Metabolism News and Research

Latest Metabolism News and Research

Excessive fructose consumption can result in non-alcoholic fatty liver disease

RNA-targeting compound restarts a healing factor silenced by heart attack

Prolonged use of bisphosphonates increases risk of atypical femur fractures

Congenital disorder of fat metabolism can cause chronic hyperreaction of the immune system

Study: Frequent use of antimicrobial drugs impairs bacterial diversity in saliva

Developing more precise, targeted therapy for a highly aggressive breast cancer

Dusp8 protein has regulatory effects on hypothalamic insulin sensitivity

Study could reveal brain cells and circuits that influence human health and metabolism in response to dietary changes

Macaques show low neutralizing antibody and cellular immune response to SARS-CoV-2

Bioinformatics identifies key genes and cellular pathways in COVID-19

Study examines the effect of low-carbohydrate, high-fat diet on older adults

A metabolic enzyme shows great potential as target for immunotherapies

Air pollution may play a role in development of cardiometabolic diseases, shows study

Study reveals a promising treatment for Parkinson's disease

Girls with anorexia nervosa can have stunted growth

Gastric bypass surgery is the most effective therapy to treat type 2 diabetes

Study may lead to new targeted therapies that inhibit the spread of cancer

Study sheds light on 500-year old mystery about the human heart

Study: Vitamin D supplementation is associated with compositional changes in a baby's microbiome

Diabetes-related complications increase with elevated levels of heart failure marker

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