Metabolism News and Research

Latest Metabolism News and Research

Researchers uncover molecular events underlying paternal diet-induced metabolic disorders in children

When parents eat low-protein or high-fat diets it can lead to metabolic disorders in their adult offspring. Now, an international team led by researchers at the RIKEN Cluster for Pioneering Research have identified a key player and the molecular events underlying this phenomenon in mice.

19 Mar 2020

Identification of 'Hodor' in the gut lining highlights potential way to curb mosquito populations

The identification of an insect-specific metal-sensing receptor in the gut lining highlights a possible new way to curb populations of disease-transmitting insects such as mosquitoes.

18 Mar 2020

$FLS care effective for patients with fragility fractures$

FLS care effective for patients with fragility fractures

For patients with fragility fractures related to underlying bone weakness, a dedicated fracture liaison service can lower the risk of subsequent fractures, suggests a study in the March 18, 2020 issue of The Journal of Bone & Joint Surgery.

18 Mar 2020

Researchers identify new way to treat Danon disease using gene therapy

Danon disease is a very rare, life-threatening condition where the fundamental biological process of removing and recycling proteins does not work.

18 Mar 2020

Using 'organs-on-a-chip' to study chronic inflammatory diseases

MIT biological engineers have created a multitissue model that lets them study the relationships between different organs and the immune system, on a specialized microfluidic platform seeded with human cells.

18 Mar 2020

EHD2 protein plays a key role in fat metabolism

Many foods - whether it's the mozzarella on your favorite pizza, the olive oil in salad dressing or hollandaise sauce during asparagus season - contain lots of fat. The fatty acids in these foods are among the essential nutrients that people need to survive.

17 Mar 2020

Changes in cellular degradation hubs can lead to cancer

A team of scientists at Uppsala University has revealed that alterations in cells’ lysosomes underly abnormal cell growth.

17 Mar 2020

Scientists use artificial intelligence to create new proteins unseen in nature

Researchers have presented a artificial intelligence method for developing new proteins that have never been seen in nature.

17 Mar 2020

$Vitamin D increases chances of regaining mobility after hip fracture$

Vitamin D increases chances of regaining mobility after hip fracture

Senior citizens who are not vitamin D deficient have a better chance of walking after hip fracture surgery, according to a Rutgers-led study.

17 Mar 2020

Key antibiotic used for treating drug-resistant TB does not work as expected

Crick and Imperial researchers have found that a key antibiotic widely used to treat drug-resistant tuberculosis does not work as expected - a finding which could be used to develop new drugs.

16 Mar 2020

Trial of cancer drug OxaliTex promises lower toxicity and more robust action

Preclinical trials indicate that a drug candidate called OxaliTex can stop the growth of cancer cells completely. OxaliTex appears to be more potent than many other common chemotherapy drugs, with less toxicity and less rapidly counteracted by mechanisms of drug resistance. The study was reported in the journal Proceedings of the National Academy of Sciences in March 2020.

16 Mar 2020

Single-drug therapy can attack several cellular targets using different modes of action

Clinicians combat the drug resistances of some cancer types by using a combination of different drugs. To make this approach more effective, chemists have designed a chemical conjugate that can simultaneously attack several cellular targets using different modes of action.

13 Mar 2020

Immunosuppressive therapy does not increase risk of vulvar or vaginal cancer in women with IBD

In a new retrospective study, researchers found that the use of immunosuppressive therapy does not increase the occurrence or recurrence of vulvar or vaginal cancer in women with inflammatory bowel disease (IBD).

11 Mar 2020

Aging and competition for nutrients determine changes in gut bacteria

Two studies with surprising discoveries: in the elderly, the bacterium E. coli evolves in a way that can become potentially pathogenic and increase the risk of disease and, according to data obtained in another study, the metabolism of the same bacterium present in the microbiota evolves differently if it is alone or accompanied by other bacteria.

11 Mar 2020

Characterization of novel L-fucose metabolism pathway in anaerobic bacteria

The genetic context in bacterial genomes and screening for potential substrates can help identify the biochemical functions of bacterial enzymes.

11 Mar 2020

Popular painkiller may have more significant effects on the liver than expected

The popular painkiller ibuprofen may have more significant effects on the liver than previously thought, according to new research from the University of California, Davis.

11 Mar 2020

Researchers visualize first structure of key enzyme that helps make triglycerides

The first structure of a lipin enzyme, which carries out an important step in the production of triglycerides, the main reservoir for long-term energy storage, will help scientists to better understand how lipins regulate the production of triglycerides.

11 Mar 2020

Metabolism News and Research

Latest Metabolism News and Research

Researchers uncover molecular events underlying paternal diet-induced metabolic disorders in children

Identification of 'Hodor' in the gut lining highlights potential way to curb mosquito populations

FLS care effective for patients with fragility fractures

Researchers identify new way to treat Danon disease using gene therapy

Using 'organs-on-a-chip' to study chronic inflammatory diseases

EHD2 protein plays a key role in fat metabolism

Changes in cellular degradation hubs can lead to cancer

Scientists use artificial intelligence to create new proteins unseen in nature

Vitamin D increases chances of regaining mobility after hip fracture

Key antibiotic used for treating drug-resistant TB does not work as expected

Trial of cancer drug OxaliTex promises lower toxicity and more robust action

Single-drug therapy can attack several cellular targets using different modes of action

Immunosuppressive therapy does not increase risk of vulvar or vaginal cancer in women with IBD

Aging and competition for nutrients determine changes in gut bacteria

Characterization of novel L-fucose metabolism pathway in anaerobic bacteria

Popular painkiller may have more significant effects on the liver than expected

Researchers visualize first structure of key enzyme that helps make triglycerides

Study uncovers novel relationships between SLCs and cytotoxic drugs in human cells

Bacteria may be involved in the development of type 2 diabetes, study shows

New discovery could lead to better strategies for preventing breast cancer metastasis

Pharmaceutical Manufacturing - Industry Focus eBook eBook

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation