Metabolism News and Research

Latest Metabolism News and Research

Study shows unexpected mechanism for lipid acquisition by breast cancer cells

High-fat diets and obesity have been shown to increase the risk of breast cancer and worsen outcomes and prognosis of breast cancer patients. A team of researchers from Dartmouth and Dartmouth-Hitchcock Norris Cotton Cancer Center led by William Kinlaw III, MD, sought to understand how fat from the diet might influence breast cancer cells.

12 Dec 2019

Researchers examine p53-deficient colon cancer cells to identify how p53 impacts metabolic adaptation

Colon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to adapt to the lack of oxygen and nutrients inside the tumor. Statins, which are often prescribed to lower cholesterol, block this metabolic pathway and cause the cancer cells to die, as scientists from the German Cancer Research Center have now discovered.

12 Dec 2019

New method reveals how microbial communities function in our bodies

In the last decade, scientists have made tremendous progress in understanding that groups of bacteria and viruses that naturally coexist throughout the human body play an important role in some vital functions like digestion, metabolism and even fighting off diseases. But understanding just how they do it remains a question.

11 Dec 2019

Experimental Alzheimer’s drugs show promise

Researchers from Salk have found that two experimental drugs named CMS121 and J147 may improve memory functions and reduce the progression of memory decline and brain degeneration in mice models of Alzheimer’s disease (AD). The researchers published their work in the latest issue of the journal eLife. The study was titled, “Elevating acetyl-CoA levels reduces aspects of brain aging.”

11 Dec 2019

Collaborative Frontiers grant to help predict behavior of the brain under metabolic stress

More than 30 million Americans have diabetes, with the vast majority having Type 2 disease. Characterized by insulin resistance and persistently high blood sugar levels, poorly controlled Type 2 diabetes has a host of well-recognized complications: compared with the general population, a greatly increased risk of kidney disease, vision loss, heart attacks and strokes, and lower limb amputations.

11 Dec 2019

New research may help guide future treatment for non-alcoholic fatty liver disease

Edith Cowan University researchers have found that a chronic disease affecting up to 80 per cent of overweight people may be causing an iron deficiency that simply leaves them too tired to get off the couch.

11 Dec 2019

Study finds that even light alcohol consumption may increase overall cancer risk

A new study suggests that even light-to-moderate alcohol consumption may increase overall cancer risk.

10 Dec 2019

Metformin shows benefits on aging and different diseases

Researchers at McMaster University have unlocked one of the secrets behind the many benefits of metformin.

9 Dec 2019

Exercise improves key measures of cardiovascular health

Eight months of daily, afterschool physical activity in previously inactive 8- to 11-year-olds with obesity and overweight improved key measures of their cardiovascular health like good cholesterol levels, aerobic fitness and percent body fat, but didn't improve others like arterial stiffness, an early indicator of cardiovascular risk, investigators report.

9 Dec 2019

The role of adenosine in neurodegeneration and brain regeneration

The role of adenosine in neurodegeneration and neuroregeneration has led to growing attention on adenosine receptors as potential drug targets in a range of brain disorders, including neuroregenerative therapy and treatment for amyotrophyic lateral sclerosis.

8 Dec 2019

Clinical trial demonstrates safety and effectiveness of oral drug to treat NASH

Patients with nonalcoholic steatohepatitis, a chronic liver disease and a leading cause for liver transplantation in the U.S., currently lack an approved drug therapy, but this may soon change.

6 Dec 2019

New study examines link between sugars and cardiovascular disease

The impact of sugars on heart health depends on the dose and type of sugar consumed, suggests a new study led by researchers at St. Michael's Hospital.

5 Dec 2019

Time-restricted eating can help treat metabolic syndrome

Metabolic syndrome affects nearly 30 percent of the U.S. population, and increases the risk for type 2 diabetes, heart disease and stroke. But lifestyle interventions such as adopting a healthy diet and increasing physical exercise are difficult to maintain and, even when combined with medication, are often insufficient to fully manage the disease.

5 Dec 2019

Ground breaking discovery could lead to new anti TB drugs

New drugs to treat strains of TB which have become resistant to treatment are now a possibility following a ground breaking discovery from the University of Surrey.

4 Dec 2019

Study reveals role of corpora amylacea in expelling brain waste substances

An article published in Proceedings of the National Academy of Sciences describes a new pathway in the central nervous system to expel waste substances from the brain through the creation of corpora amylacea, aggregates formed by glucose polymers amassing waste products.

4 Dec 2019

Researchers awarded $250,000 grant to study tumor microenvironment in lung cancer

Fueling exploration by investigators who collaborate under a research consortium partnership as recognized by the National Cancer Institute, between Rutgers Cancer Institute of New Jersey and Princeton University, the GO2 Foundation for Lung Cancer has awarded $250,000 toward the identification and development of novel strategies to address treatment resistance in non-small cell lung cancer.

3 Dec 2019

Simple ways to make the holidays safe for seniors

The menu is planned, the table is set, and the guests are invited. But if you're hosting older relatives and friends this holiday season, you'll also need to prepare your home inside and out to make sure their visit is comfortable and safe.

3 Dec 2019

Early-morning, starch-rich meal improves glycemic control among type 2 diabetics

Type 2 diabetics inject themselves with insulin, a hormone that regulates the movement of sugar into liver, muscle and fat cells, up to four times a day. But insulin injections are linked to weight gain and the loss of control of blood sugar levels. This triggers a vicious cycle of higher insulin doses, continuous weight gain, a higher incidence of cardiovascular disease and other complications.

3 Dec 2019

New treatment approach could improve outcomes for people with cystic fibrosis

A new approach to treating people with cystic fibrosis (CF) has been shown to reduce inflammation, which has the potential to reduce the need for lung transplants and lower the risk of death.

3 Dec 2019

Multiple mechanisms at work in diabetes drug metformin

Metformin is the most commonly prescribed type 2 diabetes drug, yet scientists still do not fully know how it works to control blood sugar levels. In a collaborative effort, researchers from the Salk Institute, The Scripps Research Institute and Weill Cornell Medical College have used a novel technology to investigate why it functions so well.

3 Dec 2019

Metabolism News and Research

Latest Metabolism News and Research

Study shows unexpected mechanism for lipid acquisition by breast cancer cells

Researchers examine p53-deficient colon cancer cells to identify how p53 impacts metabolic adaptation

New method reveals how microbial communities function in our bodies

Experimental Alzheimer’s drugs show promise

Collaborative Frontiers grant to help predict behavior of the brain under metabolic stress

New research may help guide future treatment for non-alcoholic fatty liver disease

Study finds that even light alcohol consumption may increase overall cancer risk

Metformin shows benefits on aging and different diseases

Exercise improves key measures of cardiovascular health

The role of adenosine in neurodegeneration and brain regeneration

Clinical trial demonstrates safety and effectiveness of oral drug to treat NASH

New study examines link between sugars and cardiovascular disease

Time-restricted eating can help treat metabolic syndrome

Ground breaking discovery could lead to new anti TB drugs

Study reveals role of corpora amylacea in expelling brain waste substances

Researchers awarded $250,000 grant to study tumor microenvironment in lung cancer

Simple ways to make the holidays safe for seniors

Early-morning, starch-rich meal improves glycemic control among type 2 diabetics

New treatment approach could improve outcomes for people with cystic fibrosis

Multiple mechanisms at work in diabetes drug metformin

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