Metabolism News and Research

Latest Metabolism News and Research

Testosterone treatment can benefit men with Type 2 diabetes

Men with Type 2 diabetes who have low testosterone levels can benefit significantly from testosterone treatment.

30 Nov 2015

Researchers reveal new technique to grow human hepatocytes in the laboratory

In new research appearing in the prestigious journal Nature Biotechnology, an international research team led by The Hebrew University of Jerusalem describes a new technique for growing human hepatocytes in the laboratory. This groundbreaking development could help advance a variety of liver-related research and applications, from studying drug toxicity to creating bio-artificial liver support for patients awaiting transplantations.

27 Nov 2015

WPI researchers awarded $1.3 million NIH grant to study use of copper to battle bacterial invader

Copper is an essential micronutrient that all organisms need to maintain healthy metabolism. But unless it is bound to proteins, copper is also toxic to cells. With a $1.3 million award from the National Institutes of Health, researchers at Worcester Polytechnic Institute will conduct a systematic study of copper in the bacteria Pseudomonas aeruginosa (P. aeruginosa), a leading cause of hospital-associated infections that is increasingly resistant to antibiotics, with the hope of discovering new drug targets that might allow cells in the body to use copper to fight back against this bacterial invader.

25 Nov 2015

Scientists show evidence for exchange of lactate between different brain cells

Nerve cells cover their high energy demand with glucose and lactate. Scientists of the University of Zurich now provide new support for this. They show for the first time in the intact mouse brain evidence for an exchange of lactate between different brain cells. With this study they were able to confirm a 20-year old hypothesis.

25 Nov 2015

Breastfeeding may offer unique benefits to women, protect against type 2 diabetes after delivery

Women with gestational diabetes who consistently and continuously breastfeed from the time of giving birth are half as likely to develop type 2 diabetes within two years after delivery, according to a study from Kaiser Permanente published today in Annals of Internal Medicine.

24 Nov 2015

Liver's cannabinoid receptors could be targeted to combat liver cancer in some patients

A new study reveals that the liver's cannabinoid receptors could be targeted to fight liver cancer in some patients; and it offers a way to predict what treatments have the best chance of working.

23 Nov 2015

Interaction between two brain proteins has substantial effect on memory formation

In a new study that could have implications for future drug discovery efforts for a number of neurodegenerative diseases, scientists from the Florida campus of The Scripps Research Institute (TSRI) have found that the interaction between a pair of brain proteins has a substantial and previously unrecognized effect on memory formation.

20 Nov 2015

Innovative microbiome technology may help fight certain infections

Stony Brook University and Ortek Therapeutics, Inc. announced today that two patent applications were filed in the United States and internationally for nutrient based compositions utilizing an innovative microbiome technology that may help combat certain infections.

20 Nov 2015

New approach to regulate people's cholesterol levels

A discovery about how the body deals with the cholesterol contained within its dying cells has suggested an exciting new approach to control people's cholesterol levels - and thus their risk of developing heart disease.

19 Nov 2015

Sildenafil drug improves insulin sensitivity in people at risk for diabetes

The drug sildenafil, sold as Viagra and other brand names, improves insulin sensitivity in people at risk for diabetes, researchers at Vanderbilt University Medical Center reported today.

19 Nov 2015

Potential treatment strategy for glycogen storage disease

Researchers from the Duke-NUS Graduate Medical School Singapore and Duke Medicine have identified a potential treatment strategy for an often-fatal inherited glycogen storage disease.

18 Nov 2015

Elite endurance athletes who eat few carbohydrates burn more fat during prolonged exercise

Elite endurance athletes who eat very few carbohydrates burned more than twice as much fat as high-carb athletes during maximum exertion and prolonged exercise in a new study - the highest fat-burning rates under these conditions ever seen by researchers.

18 Nov 2015

Researchers identify a mechanism that may explain association between obesity and cancer

Researchers have identified a mechanism that allows cancer cells to respond and grow rapidly when levels of sugar in the blood rise. This may help to explain why people who develop conditions in which they have chronically high sugar levels in their blood, such as obesity, also have an increased risk of developing certain types of cancer.

18 Nov 2015

TSRI scientists discover first-in-class compounds that target persistent tuberculosis

Tuberculosis has been infecting humans for several millennia, making it one of the most horribly successful diseases in history. Today, it is still a major killer, responsible for some 1.5 million deaths each year.

18 Nov 2015

Viking submits IND application to FDA to conduct VK2809 Phase 2 study in patients with LDL-C and fatty liver disease

Viking Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on the development of novel, first-in-class or best-in-class therapies for metabolic and endocrine disorders, today announced that it has submitted an investigational new drug (IND) application to the U.S. Food and Drug Administration to conduct a Phase 2 study of VK2809 in patients with hypercholesterolemia and fatty liver disease.

17 Nov 2015

Scientists show how absence of microbiota has remarkable effect against obesity

In the past few years, research on gut microbiota (that is, all microorganisms, mainly bacteria, inhabiting our gut) has started to unravel its tremendous role in our body, and how it symbiotically affects the functioning of our organs. In particular, microbiota has also an impact on the way calories are absorbed and how fat cells develop.

17 Nov 2015

Changes in cellular metabolites regulate earliest stages of embryonic stem cell development

Changes in cellular metabolites have been shown to regulate embryonic stem cell development at the earliest stages of life. Metabolites are simple compounds generated during life-sustaining chemical activities in cells.

17 Nov 2015

CRI scientists identify emergency blood-formation system inside the body

Scientists at the Children's Medical Center Research Institute at UT Southwestern have determined how the body responds during times of emergency when it needs more blood cells. In a study published in Nature, researchers report that when tissue damage occurs, in times of excessive bleeding, or during pregnancy, a secondary, emergency blood-formation system is activated in the spleen.

17 Nov 2015

Helmholtz Centre for Infection Research scientists identify promising antitumor agent

Support comes out of the ground: Scientists from the Helmholtz Centre for Infection Research in Germany have identified a terrestrial myxobacterium as a promising source for the bengamide class of natural products, which were originally thought to be secondary metabolites of marine sponges only.

17 Nov 2015

Diabetes prevention begins in the womb

60 million people worldwide are living with diabetes mellitus, and one in ten people over the age of 25 will develop the condition (type 2) at some stage in their lives. Globally, around 3.4 million people die from diabetes and its consequences every year. "Every six seconds, somebody somewhere in the world dies from diabetes", says Alexandra Kautzky-Willer from the Department of Endocrinology and Metabolism at the MedUni Vienna's University Department of Internal Medicine III.

13 Nov 2015

Metabolism News and Research

Latest Metabolism News and Research

Testosterone treatment can benefit men with Type 2 diabetes

Researchers reveal new technique to grow human hepatocytes in the laboratory

WPI researchers awarded $1.3 million NIH grant to study use of copper to battle bacterial invader

Scientists show evidence for exchange of lactate between different brain cells

Breastfeeding may offer unique benefits to women, protect against type 2 diabetes after delivery

Liver's cannabinoid receptors could be targeted to combat liver cancer in some patients

Interaction between two brain proteins has substantial effect on memory formation

Innovative microbiome technology may help fight certain infections

New approach to regulate people's cholesterol levels

Sildenafil drug improves insulin sensitivity in people at risk for diabetes

Potential treatment strategy for glycogen storage disease

Elite endurance athletes who eat few carbohydrates burn more fat during prolonged exercise

Researchers identify a mechanism that may explain association between obesity and cancer

TSRI scientists discover first-in-class compounds that target persistent tuberculosis

Viking submits IND application to FDA to conduct VK2809 Phase 2 study in patients with LDL-C and fatty liver disease

Scientists show how absence of microbiota has remarkable effect against obesity

Changes in cellular metabolites regulate earliest stages of embryonic stem cell development

CRI scientists identify emergency blood-formation system inside the body

Helmholtz Centre for Infection Research scientists identify promising antitumor agent

Diabetes prevention begins in the womb

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation