Metabolism News and Research

Latest Metabolism News and Research

Using antidepressant drug during first trimester of pregnancy may increase risk of birth defects

Using paroxetine--a medication prescribed to treat conditions including depression, obsessive-compulsive disorder, anxiety and posttraumatic stress disorder--during the first trimester of pregnancy may increase newborns' risk of congenital malformations and cardiac malformations. That's the conclusion of a recent analysis published in the British Journal of Clinical Pharmacology.

6 Jan 2016

Drug-microbe interactions may contribute to adverse effects, lessen effectiveness of NSAID

A nonsteroidal anti-inflammatory drug (NSAID) changed the composition and diversity of gut microbes, which in turn shaped how the drug is broken down and ultimately, cut its effectiveness, according to an animal study from the Perelman School of Medicine at the University of Pennsylvania.

5 Jan 2016

Researchers to undertake long-term clinical trial of artificial pancreas system for type 1 diabetes patients

Researchers will soon undertake one of the largest-ever long-term clinical trials of a system designed to help regulate blood sugar levels of individuals with type 1 diabetes mellitus. If the so-called artificial pancreas system performs in patients as hoped, it could lead to commercial trials and eventual regulatory approval in the United States and abroad.

5 Jan 2016

Nestlé Health Science recognizes Christelle Leiker with OPTIFAST "INSPIRE" award

Nestlé Health Science today recognized Christelle Leiker, Certified Nurse Practitioner, for her unwavering commitment to promoting the health and well-being of her patients. Christelle practices at the Texas Center for Obesity and General Surgery, where she runs the nonsurgical weight management program.

31 Dec 2015

New model provides images of single cell with micrometer resolution

Thermal properties of cells regulate their ability to store, transport or exchange heat with their environment. So gaining control of these properties is of great interest for optimizing cryopreservation -- the process of freezing and storing blood or tissues, which is also used when transporting organs for transplants.

30 Dec 2015

Newly discovered molecular mechanism may provide alternative explanation for antibiotic resistance

The bacterium B. cereus had so far been considered to be exclusively endospore-forming. In response to harsh conditions, the bacteria form protective endospores enabling them to remain dormant for extended periods. When conditions are more favourable, the endospores reactivate to become fully functioning bacteria.

28 Dec 2015

Researchers identify liver-derived hormone that regulates sugar intake

We all love our sugar, especially during the holidays. Cookies, cake, and candy are simply irresistible. While sugar cravings are common, the physiological mechanisms that trigger our "sweet tooth" are not well defined.

24 Dec 2015

Healthier weight using genetic data for customized diets and physical activity plans

Some health experts predict that the next big advance in helping overweight people achieve a healthier weight will be to use an individual's genetic data to customize diets and physical activity plans, an approach known as "precision weight loss.

24 Dec 2015

Novel antibody improves glucose regulation and reduces fatty liver in obese mice

A new study by researchers from Harvard T.H. Chan School of Public Health and colleagues describes the pre-clinical development of a therapeutic that could potentially be used to treat type 2 diabetes, fatty liver disease, and other metabolic diseases.

24 Dec 2015

Working Group identifies many potential genetic contributors to weight loss

In the midst of the holiday season, celebratory get-togethers can mean overindulging on treats and high-calorie foods, leaving many of us struggling to keep off the extra pounds. With as many as two-thirds of American adults already carrying excess weight, and one third with obesity, maintaining weight can be the biggest challenge, say researchers.

24 Dec 2015

Forge Therapeutics obtains exclusive license to patent rights related to novel metalloprotein inhibitors

Forge Therapeutics, Inc., a biotechnology company developing innovative medicines using a breakthrough drug discovery platform targeting metalloproteins, announced today it has obtained an exclusive license from the University of California San Diego to patent rights related to novel metalloprotein inhibitors discovered in the laboratory of Forge Therapeutics scientific co-founder Professor Seth Cohen, Ph.D.

22 Dec 2015

New mathematical models shed light on complex interactions of stem cell function in neural tissue

New research has shed light on the complex interactions of stem cell function and molecular diffusion in neural tissue, which may explain many phenomena from stem cell differentiation to the formation of the cortex of the brain. While researching new methods of reconstructing 3D neural tissue and neural pathways in the brain and spinal cord, Dr. Richard McMurtrey devised new mathematical approaches for understanding the concentration of nutrients within the 3D tissue constructs and how this could affect tissue growth.

22 Dec 2015

Yale researchers reveal why chronic overeating tied to increased risk of depression

Chronic overeating and stress are tied to an increased risk of depression and anxiety, and in a new study, Yale researchers explain why that happens and suggest a possible solution.

22 Dec 2015

Scientists outline molecular blueprints of tiny cellular 'nanomachine'

Scientists have drawn up molecular blueprints of a tiny cellular ‘nanomachine’, whose evolution is an extraordinary feat of nature, by using one of the brightest X-ray sources on Earth.

21 Dec 2015

Coffee may help improve athletic endurance

The caffeine in a morning cup of coffee could help improve athletic endurance, according to a new University of Georgia review study.

20 Dec 2015

Researchers elucidate structure of mTORC1 protein

For a long time it has been known that the protein TOR - Target of Rapamycin - controls cell growth and is involved in the development of diseases such as cancer and diabetes. Researchers at the University of Basel's Biozentrum together with scientists from ETH Zurich have now examined the structure of mammalian TOR complex 1 (mTORC1) in more detail.

18 Dec 2015

Multiple small doses of targeted radiation therapy more effective at destroying pituitary gland tumors

A recent patient study at Houston Methodist Hospital proved that multiple small doses of highly focused radiation therapy is safer and more effective than a single larger dose of radiation at destroying pituitary gland tumors.

18 Dec 2015

Novel strategies on the way for difficult-to-treat head and neck cancer

Novel strategies are on the way for difficult-to-treat and advanced head and neck cancer, the most heterogeneous group of malignancies which are generally associated with poor survival, and encouraging results have been presented at the first ESMO Asia 2015 Congress in Singapore.

17 Dec 2015

Zoledronate drug can protect stem cells from ageing

Stem cells can be protected from the effects of ageing by a drug currently used to treat patients with osteoporosis, a breakthrough study has found.

17 Dec 2015

Study examines links between genetic background, physical activity level and lifespan

Animal studies have already shown that a strong link exists between genetic background and physical activity level. The purpose of our study was to investigate the associations between genetic background, physical activity level, and lifespan.

17 Dec 2015

Metabolism News and Research

Latest Metabolism News and Research

Using antidepressant drug during first trimester of pregnancy may increase risk of birth defects

Drug-microbe interactions may contribute to adverse effects, lessen effectiveness of NSAID

Researchers to undertake long-term clinical trial of artificial pancreas system for type 1 diabetes patients

Nestlé Health Science recognizes Christelle Leiker with OPTIFAST "INSPIRE" award

New model provides images of single cell with micrometer resolution

Newly discovered molecular mechanism may provide alternative explanation for antibiotic resistance

Researchers identify liver-derived hormone that regulates sugar intake

Healthier weight using genetic data for customized diets and physical activity plans

Novel antibody improves glucose regulation and reduces fatty liver in obese mice

Working Group identifies many potential genetic contributors to weight loss

Forge Therapeutics obtains exclusive license to patent rights related to novel metalloprotein inhibitors

New mathematical models shed light on complex interactions of stem cell function in neural tissue

Yale researchers reveal why chronic overeating tied to increased risk of depression

Scientists outline molecular blueprints of tiny cellular 'nanomachine'

Coffee may help improve athletic endurance

Researchers elucidate structure of mTORC1 protein

Multiple small doses of targeted radiation therapy more effective at destroying pituitary gland tumors

Novel strategies on the way for difficult-to-treat head and neck cancer

Zoledronate drug can protect stem cells from ageing

Study examines links between genetic background, physical activity level and lifespan

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation