Metabolism News and Research

Latest Metabolism News and Research

Ambrisentan cleared for use with phenprocoumon

Starting treatment with ambrisentan does not necessitate adjusting the dose of the oral anticoagulant phenprocoumon in patients with pulmonary hypertension who require both medications, report researchers.

7 May 2014

Controlling low-density lipoprotein-cholesterol levels: an interview with Jay Edelberg, M.D., Sanofi and Bill Sasiela, Ph.D., Regeneron

Lipids, primarily cholesterol and triglycerides, come from two sources: what is naturally manufactured in the liver and what comes from the intestines through the diet.

From Sanofi 7 May 2014

Snacking linked with abdominal fat and fatty liver

Researchers from The Netherlands found that snacking on high-fat and high-sugar foods was independently associated with abdominal fat and fatty liver (hepatic steatosis).

7 May 2014

Novartis presents Phase III results of Signifor LAR therapy in patients with acromegaly

Novartis today presented results from a pivotal Phase III trial of investigational therapy Signifor® LAR (pasireotide LAR; SOM230) in patients with acromegaly for whom current standard of care provides inadequate disease control.

6 May 2014

Factors that lead to diabetes contribute to low milk supply in some new mothers

New studies provide fresh evidence that the same factors that lead to diabetes contribute to low milk supply in some new mothers.

6 May 2014

Study reveals how ovarian cancer metabolism changes between early, late stages

A Rice University-led analysis of the metabolic profiles of hundreds of ovarian tumors has revealed a new test to determine whether ovarian cancer cells have the potential to metastasize, or spread to other parts of the body. The study also suggests how ovarian cancer treatments can be tailored based on the metabolic profile of a particular tumor.

6 May 2014

DNA 'sat nav' allows direct access to homes of ancestors alive 1,000 years ago

Tracing where your DNA was formed over 1,000 years ago is now possible due to a revolutionary technique developed by a team of international scientists led by experts from the University of Sheffield.

2 May 2014

Second Genome, Pfizer partner to conduct microbiome research to gain new insights into obesity

Second Genome announced today that it has entered into an agreement with Pfizer Inc. to conduct extensive microbiome research in a large observational study aimed at gaining new insights into obesity and metabolic disease.

2 May 2014

Possible link between aggressive prostate cancer and vitamin D deficiency

Vitamin D deficiency was an indicator of aggressive prostate cancer and spread of the disease in European-American and African-American men who underwent their first prostate biopsy because of abnormal prostate-specific antigen (PSA) and/or digital rectal examination (DRE) test results, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

1 May 2014

Research helps unpick long-standing mystery about how dietary fibre supresses appetite

New research has helped unpick a long-standing mystery about how dietary fibre supresses appetite. In a study led by Imperial College London and the Medical Research Council (MRC), an international team of researchers identified an anti-appetite molecule called acetate that is naturally released when we digest fibre in the gut.

30 Apr 2014

TSRI scientists identify molecular pathways that resveratrol uses to achieve beneficial action

Resveratrol has been much in the news as the component of grapes and red wine associated with reducing “bad cholesterol,” heart disease and some types of cancer. Also found in blueberries, cranberries, mulberries, peanuts and pistachios, resveratrol is associated with beneficial health effects in aging, inflammation and metabolism.

30 Apr 2014

Researchers develop tool to identify biogeography of worldwide individuals

Biogeographical data is useful in screening for disease risk and drug sensitivity associated with certain ethnic groups. A team of researchers, including an investigator from Children's Hospital Los Angeles, has developed a tool to accurately identify the biogeography of worldwide individuals. Previous tools were accurate in identifying place of origin within homogeneous European populations but highly inaccurate for places with significant immigration, such as the U.S.

30 Apr 2014

Otsuka's Deltyba gets EC marketing authorization for MDR-TB treatment

Otsuka Pharmaceutical Co., Ltd. today announced that the European Commission has granted a marketing authorization for Deltyba (delamanid) for use as part of an appropriate combination regimen for pulmonary multidrug-resistant tuberculosis (MDR-TB) in adult patients when an effective treatment regimen cannot otherwise be composed for reasons of resistance or tolerability.

30 Apr 2014

Gokhan S. Hotamisligil named recipient of the 9th Danone International Prize for Nutrition

Danone Institute International announced today that prominent scientist Gokhan S. Hotamisligil, MD, PhD, is the recipient of the 9th Danone International Prize for Nutrition for his outstanding research in immunology and metabolic diseases.

30 Apr 2014

Scientists reveal molecular secrets behind resveratrol's health benefits

Resveratrol has been much in the news as the component of grapes and red wine associated with reducing "bad cholesterol," heart disease and some types of cancer. Also found in blueberries, cranberries, mulberries, peanuts and pistachios, resveratrol is associated with beneficial health effects in aging, inflammation and metabolism.

29 Apr 2014

Higher calcium intake appears to mitigate impact of some of the risk genes for type 2 diabetes

Study shows calcium intake mitigates genetic risk for increased body fat in African-American children, a population with historically low calcium intake and high risk for diabetes.

29 Apr 2014

Armetheon reaches agreement with FDA on SPA for final pivotal trial of tecarfarin

Armetheon, Inc., today announced that it has reached agreement with the U.S. Food and Drug Administration (FDA) on a Special Protocol Assessment (SPA) for the final pivotal trial of tecarfarin.

29 Apr 2014

Studies provide insight on quality of kidney and liver transplantation

The quality of kidney and liver donations is fundamentally important for the longevity of transplants and the health of recipients. That’s why it’s critical to know which organs are suitable for transplantation, as well as to use techniques that preserve an organ’s function after donation.

29 Apr 2014

Research to understand how low blood sugars cause irregular heartbeats in diabetes

Dangerous overnight blood sugar levels often go undetected and cause prolonged periods of heart rhythm disturbances in older patients with Type 2 diabetes and associated heart problems, new research reveals.

29 Apr 2014

Viewpoints: 'Pinocchios' for the Koch brothers; Obamacare 'miracle'; the law's effect on hiring

The health care ads being run by Americans for Prosperity - one of the many frantically waving arms of the Koch brothers - are a gift to fact checkers everywhere. Because they deliberately twist the truth to persuade people to "stop supporting Obamacare," they have become a machine for producing "Pinocchios," the mendacity rating system used by Glenn Kessler at The Washington Post (David Firestone, 4/24).

26 Apr 2014

Metabolism News and Research

Latest Metabolism News and Research

Ambrisentan cleared for use with phenprocoumon

Controlling low-density lipoprotein-cholesterol levels: an interview with Jay Edelberg, M.D., Sanofi and Bill Sasiela, Ph.D., Regeneron

Snacking linked with abdominal fat and fatty liver

Novartis presents Phase III results of Signifor LAR therapy in patients with acromegaly

Factors that lead to diabetes contribute to low milk supply in some new mothers

Study reveals how ovarian cancer metabolism changes between early, late stages

DNA 'sat nav' allows direct access to homes of ancestors alive 1,000 years ago

Second Genome, Pfizer partner to conduct microbiome research to gain new insights into obesity

Possible link between aggressive prostate cancer and vitamin D deficiency

Research helps unpick long-standing mystery about how dietary fibre supresses appetite

TSRI scientists identify molecular pathways that resveratrol uses to achieve beneficial action

Researchers develop tool to identify biogeography of worldwide individuals

Otsuka's Deltyba gets EC marketing authorization for MDR-TB treatment

Gokhan S. Hotamisligil named recipient of the 9th Danone International Prize for Nutrition

Scientists reveal molecular secrets behind resveratrol's health benefits

Higher calcium intake appears to mitigate impact of some of the risk genes for type 2 diabetes

Armetheon reaches agreement with FDA on SPA for final pivotal trial of tecarfarin

Studies provide insight on quality of kidney and liver transplantation

Research to understand how low blood sugars cause irregular heartbeats in diabetes

Viewpoints: 'Pinocchios' for the Koch brothers; Obamacare 'miracle'; the law's effect on hiring

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging