Metabolism News and Research

Latest Metabolism News and Research

Study explores dangers of switching from MDMA to mephedrone

Contrary to popular belief among recreational drug users, mephedrone has several important differences when compared with MDMA, commonly known as ecstasy. These differences mean that mephedrone could leave a user with acute withdrawal symptoms and indicate that it may have a higher potential for developing dependence than MDMA according to a study published in British Journal of Pharmacology.

26 Mar 2014

UMass Medical School students win 2014 Harold M. Weintraub Graduate Student Award

Colin Conine and Emma Watson, PhD students in the Graduate School of Biomedical Sciences (GSBS) at the University of Massachusetts Medical School, received the 2014 Harold M. Weintraub Graduate Student Award for research into the mechanisms governing epigenetic inheritance and the complex interactions between diet, gene expression and physiology.

26 Mar 2014

Scientists discover why cerebellar granule cell neurons in A-T patients fail to repair DNA damage

A team of scientists, led by Stuart Lipton, M.D., Ph.D., professor and director of the Neuroscience and Aging Research Center at Sanford-Burnham Medical Research Institute, recently discovered why cerebellar granule cell neurons in patients suffering from ataxia-telangiectasia (A-T) were unable to repair DNA damage and thus died.

26 Mar 2014

Agios initiates AG-120 Phase 1 study to evaluate advanced solid tumors with IDH1 mutation

Agios Pharmaceuticals, Inc., a leader in the fields of cancer metabolism and inborn errors of metabolism, today announced dose administration for the first patient in a Phase 1 study of AG-120 in patients with advanced solid tumors with an isocitrate dehydrogenase-1 (IDH1) mutation.

25 Mar 2014

Diabetes drug reduces amyloid-beta peptides, improves memory in experimental AD models

Researchers from Boston University School of Medicine have found that the diabetic drug, pramlintide, reduces amyloid-beta peptides, a major component of Alzheimer's disease (AD) in the brain and improves learning and memory in two experimental AD models.

25 Mar 2014

High-protein meal and exercise recipe for calorie-burning in some women

New research shows that for some women, a high-protein meal followed by 30 minutes of moderate exercise is an effective way of burning calories, especially when compared to exercising on an empty stomach.

24 Mar 2014

Proteins that regulate energy metabolism are essential for stem cell formation

Proteins that regulate energy metabolism are essential for stem cell formation, University of Washington researchers find.

21 Mar 2014

Up to a third of obese kids 'metabolically healthy'

Digits on a scale can help determine a child's weight, but their overall health status can be influenced by other factors such as physical activity, diet and screen time, according to new research from the University of Alberta and Alberta Health Services.

20 Mar 2014

Insulin-secreting beta cells of pancreas have capacity to regenerate, say scientists

Vanderbilt University scientists have found evidence that the insulin-secreting beta cells of the pancreas, which are either killed or become dysfunctional in the two main forms of diabetes, have the capacity to regenerate.

20 Mar 2014

Research aims to develop world's first lipid database for healthy persons

A new international research consortium, led by the National University of Singapore (NUS), aims to develop the world's first lipid database for healthy persons of different racial and ethnic groups.

20 Mar 2014

Trimethoprim is more effective against streptococci than expected, says research

The focus of his team was also on samples, in which the bacteria failed to respond to the agent. They discovered two types of resistance. "Spontaneous mutations can occur in the gene for dihydrofolate reductase rendering trimethoprim no longer able to attack the changed enzyme, which means it becomes ineffective," Nitsche-Schmitz explained.

20 Mar 2014

Scientists step in with new way to determine drug safety without using animals

As some countries and companies roll out new rules to limit animal testing in pharmaceutical products designed for people, scientists are stepping in with a new way to test therapeutic drug candidates and determine drug safety and drug interactions — without using animals.

19 Mar 2014

Professor receives 2014 Rolf Luft Award for research on diabetes and endocrinology

Dr. Roger Unger, Professor of Internal Medicine at UT Southwestern Medical Center has been awarded the 2014 Rolf Luft Award for his identification of glucagon as a pancreatic hormone that raises blood sugar levels, having the opposite effect of insulin.

18 Mar 2014

High-precision Lens Profiler from Phasefocus assists practitioners studying clinical complications arising from corneal oxygen deficiency

Phase Focus Ltd (Phasefocus), the company that is revolutionising microscopy and imaging with the Phasefocus Virtual Lens®, reports on how optical lens practitioners are using the Phasefocus high-precision Lens Profiler to study potential clinical complications arising from corneal oxygen deficiency.

From Phase Focus Limited 18 Mar 2014

Study: Identifying biomarkers could lead to earlier detection of preeclampsia

Identifying biomarkers could lead to earlier detection of preeclampsia, which in turn can lead to healthier mothers and children, according to a collaborative study from the Centre of Molecular Inflammation Research (CEMIR) and the MR Cancer Group at the Norwegian University of Science and Technology (NTNU).

18 Mar 2014

People who experience chronic sleep disturbance could face earlier onset of dementia, Alzheimer's

People who experience chronic sleep disturbance—either through their work, insomnia or other reasons—could face an earlier onset of dementia and Alzheimer's, according to a new pre-clinical study by researchers at Temple University.

18 Mar 2014

S. pneumoniae thrives in human saliva

Streptococcus pneumoniae is able to survive and thrive in human saliva, Dutch researchers have shown.

17 Mar 2014

Research on diverse health benefits of oats in protecting heart

Eleven top scientists from around the globe presented the latest findings on the powerful compounds found in oats in a scientific session titled, Physicochemical Properties and Biological Functionality of Oats, at the 247th Annual Conference of the American Chemical Society in Dallas, TX

17 Mar 2014

FDA grants Fast Track designation to Edison’s lead drug EPI-743

Edison Pharmaceuticals today announced that the United States Food and Drug Administration granted Fast Track designation to EPI-743, the company's lead drug, for the treatment of Friedreich's ataxia. EPI-743 is being developed for pediatric and adult mitochondrial disease, including Friedreich's ataxia.

17 Mar 2014

Researcher discover new chemical class that attacks two key cancer cell building block targets

Imagine cutting down the growth of cancer cells at their earliest stages to halt tumor growth. Research conducted by leading cancer metabolism researchers at Stony Brook University, Paul M. Bingham, PhD, and Zuzana Zachar, PhD, is showing promise in this approach with their clinical investigation of a new class of compounds that disrupt cancer cell mitochondrial metabolism.

14 Mar 2014

Metabolism News and Research

Latest Metabolism News and Research

Study explores dangers of switching from MDMA to mephedrone

UMass Medical School students win 2014 Harold M. Weintraub Graduate Student Award

Scientists discover why cerebellar granule cell neurons in A-T patients fail to repair DNA damage

Agios initiates AG-120 Phase 1 study to evaluate advanced solid tumors with IDH1 mutation

Diabetes drug reduces amyloid-beta peptides, improves memory in experimental AD models

High-protein meal and exercise recipe for calorie-burning in some women

Proteins that regulate energy metabolism are essential for stem cell formation

Up to a third of obese kids 'metabolically healthy'

Insulin-secreting beta cells of pancreas have capacity to regenerate, say scientists

Research aims to develop world's first lipid database for healthy persons

Trimethoprim is more effective against streptococci than expected, says research

Scientists step in with new way to determine drug safety without using animals

Professor receives 2014 Rolf Luft Award for research on diabetes and endocrinology

High-precision Lens Profiler from Phasefocus assists practitioners studying clinical complications arising from corneal oxygen deficiency

Study: Identifying biomarkers could lead to earlier detection of preeclampsia

People who experience chronic sleep disturbance could face earlier onset of dementia, Alzheimer's

S. pneumoniae thrives in human saliva

Research on diverse health benefits of oats in protecting heart

FDA grants Fast Track designation to Edison’s lead drug EPI-743

Researcher discover new chemical class that attacks two key cancer cell building block targets

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging