Metabolism News and Research

Latest Metabolism News and Research

Genomic study identifies MCU that regulates calcium transport into mitochondria

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, and collaborators at Massachusetts General Hospital (MGH), the Broad Institute, and the David H. Koch Institute for Integrative Cancer Research at the Massachusetts Institute of Technology (MIT), today announced new findings published in Nature.

20 Jun 2011

Short warm-ups permit greater cycling performance

Coaches, physiologists and athletes alike will attest to the importance of warming up before athletic competition. Warming up increases muscle temperature, accelerates oxygen uptake kinetics and increases anaerobic metabolism, all of which enhance performance.

18 Jun 2011

$Future burden of fractures could be avoided with increased treatment uptake: Study$

Future burden of fractures could be avoided with increased treatment uptake: Study

It pays to prevent fractures. That's one of the main findings of a landmark report 'Osteoporosis - Burden, Healthcare provision and Opportunities in the European Union' newly published in the journal Archives of Osteoporosis.

18 Jun 2011

Roche RTCA HT Instrument allows fully-automated impedance screens for GPCRs

Label-free technologies have entered the stage of cellular drug discovery and high-throughput screening (HTS). For the measurement of G protein-coupled receptor (GPCR) activation electrical impedance represents an excellent universal readout technology, since different signaling pathways can be measured in one assay format using recombinant as well as primary cells.

17 Jun 2011

Medical societies urge diabetes patients to remain on their prescribed medications

Diabetes leaders today are responding to the announcement made by the U.S. Food and Drug Administration (FDA) yesterday that the use of the diabetes medication Actos (pioglitazone) for more than one year may be associated with an increased risk of bladder cancer.

17 Jun 2011

Snack-based diet can increase risk of obesity

A high-fat diet can be bad for your health. However, a snack-based "cafeteria"-style diet of highly palatable, energy-dense foods is even worse, according to new research.

17 Jun 2011

Children born pre-term have persistent drive to succeed

In the longest running U.S. study of premature infants who are now 23 years old, University of Rhode Island Professor of Nursing Mary C. Sullivan has found that premature infants are less healthy, have more social and school struggles and face a greater risk of heart-health problems in adulthood.

16 Jun 2011

Magnesium essential for absorption and metabolism of vitamin D and calcium

Magnesium deficiency is an important factor in the results obtained from vitamin D. According to Dr. Carolyn Dean, MD, ND, magnesium expert and Medical Director of the nonprofit Nutritional Magnesium Association, the effectiveness and benefits of vitamin D are greatly undermined in the absence of adequate levels of magnesium in the body.

15 Jun 2011

High FGF-23 hormone levels linked to increased risk of end-stage renal disease and death

Patients in the early stages of chronic kidney disease who had elevated levels of the endocrine hormone fibroblast growth factor 23 (that regulates phosphorus metabolism) had an associated increased risk of end-stage renal disease and death, according to a study in the June 15 issue of JAMA.

15 Jun 2011

Research reveals how humans of different ancestry process polyunsaturated fat

Over the past decade, much progress has been made regarding the understanding and promise of personalized medicine. Scientists are just beginning to consider the impact of gene-diet interactions in different populations in regards to disease prevention and treatment.

15 Jun 2011

Sangart commences MP4OX Phase 2b study in acute traumatic injury

Sangart, Inc., a global biopharmaceutical company dedicated to developing life-saving medicines specifically designed to enhance the perfusion and oxygenation of ischemic tissues through targeted oxygen and other gas delivery, today announced the initiation of a Phase 2b study designed to evaluate the efficacy and safety of MP4OX treatment plus standard of care in severely injured trauma patients with lactic acidosis due to hemorrhagic shock.

15 Jun 2011

Study links cysteine with obesity-related diseases

People with high levels of the amino acid cysteine carry 6-10 kilograms more fat than other people. Norwegian researchers studying this phenomenon are generating knowledge which could help to prevent and treat life-threatening obesity.

15 Jun 2011

New findings from Deplin clinical trial on major depressive disorder presented at NCDEU

New findings from a multi-center, randomized, placebo-controlled clinical study of Deplin 15mg added to commonly prescribed antidepressants known as selective serotonin reuptake inhibitors showed that all patients who achieved remission at 30 days using Deplin 15mg adjuvant therapy, and who chose to enter a 12 month maintenance phase, maintained their remission after a year of treatment.

14 Jun 2011

Frontal cerebral thermal transfer can eliminate insomnia symptoms

People with primary insomnia may be able to find relief by wearing a cap that cools the brain during sleep, suggests a research abstract that will be presented Monday, June 13, in Minneapolis, Minn., at SLEEP 2011, the 25th Anniversary Meeting of the Associated Professional Sleep Societies LLC (APSS).

13 Jun 2011

MCMs mediate crosstalk between cell division machinery and oxygen-sensing protein

13 Jun 2011

Cell division linked to oxygen levels: Johns Hopkins research

Cells grow abundant when oxygen is available, and generally stop when it is scarce. Although this seems straightforward, no direct link ever has been established between the cellular machinery that senses oxygen and that which controls cell division. Now, in the June 10 issue of Molecular Cell, researchers at Johns Hopkins report that the MCM proteins, which promote cell division, also directly control the oxygen-sensing HIF-1 protein.

12 Jun 2011

Amylin disappointed with U.S. District Court's ruling in BYETTA preliminary injunction

Amylin Pharmaceuticals, Inc. today issued the following statement regarding the decision of the United States District Court for the Southern District of California to deny its motion for a preliminary injunction to enjoin Eli Lilly and Company from engaging in anticompetitive activity and breaching its diabetes collaboration agreement with Amylin.

10 Jun 2011

Tips for pregnant women during summer

Hot, humid and pregnant. Many women would call that a recipe for misery. But UAB obstetrician Kim Hoover, M.D., says there are real medical conditions that pregnant women should guard against to stay safe and healthy as the temperature rises.

10 Jun 2011

U.S. FDA announces safety label changes for cholesterol-lowering medication, simvastatin

The U.S. Food and Drug Administration today is announcing safety label changes for the cholesterol-lowering medication simvastatin because the highest approved dose--80 milligram (mg)--has been associated with an elevated risk of muscle injury or myopathy, particularly during the first 12 months of use.

9 Jun 2011

TD2, Imaging Endpoints team up to enable rapid development of anti-cancer drugs

TGen Drug Development (TD2) and Imaging Endpoints have teamed up to enable the rapid development of anti-cancer drugs and deliver them faster to patients in need, the companies announced today.

9 Jun 2011

Metabolism News and Research

Latest Metabolism News and Research

Genomic study identifies MCU that regulates calcium transport into mitochondria

Short warm-ups permit greater cycling performance

Future burden of fractures could be avoided with increased treatment uptake: Study

Roche RTCA HT Instrument allows fully-automated impedance screens for GPCRs

Medical societies urge diabetes patients to remain on their prescribed medications

Snack-based diet can increase risk of obesity

Children born pre-term have persistent drive to succeed

Magnesium essential for absorption and metabolism of vitamin D and calcium

High FGF-23 hormone levels linked to increased risk of end-stage renal disease and death

Research reveals how humans of different ancestry process polyunsaturated fat

Sangart commences MP4OX Phase 2b study in acute traumatic injury

Study links cysteine with obesity-related diseases

New findings from Deplin clinical trial on major depressive disorder presented at NCDEU

Frontal cerebral thermal transfer can eliminate insomnia symptoms

MCMs mediate crosstalk between cell division machinery and oxygen-sensing protein

Cell division linked to oxygen levels: Johns Hopkins research

Amylin disappointed with U.S. District Court's ruling in BYETTA preliminary injunction

Tips for pregnant women during summer

U.S. FDA announces safety label changes for cholesterol-lowering medication, simvastatin

TD2, Imaging Endpoints team up to enable rapid development of anti-cancer drugs

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut