Metabolism News and Research

Latest Metabolism News and Research

Regulus obtains exclusive rights from NYU for miR-33a, 33b to treat metabolic diseases

Regulus Therapeutics Inc., a biopharmaceutical company leading the discovery and development of innovative new medicines targeting microRNAs, today announced that it has obtained exclusive rights from New York University for intellectual property covering methods of use in modulating microRNA-33a and microRNA-33b for metabolic diseases such as atherosclerosis and metabolic syndrome.

31 Mar 2011

Roche launces new GS GType HLA Primer Sets for HLA genotyping

454 Life Sciences, a Roche Company, announced today the launch and immediate availability of the new GS GType HLA Primer Sets for high- and medium-resolution genotyping of class I and class II loci of the Human Leukocyte Antigen (HLA) genes.

30 Mar 2011

DSP, Intercept enter license agreement for OCA

Dainippon Sumitomo Pharma Co, Ltd. and Intercept Pharmaceuticals, Inc. today announced that they have entered into an exclusive licensing agreement for the development and commercialization of Intercept's first-in-class FXR agonist obeticholic acid.

30 Mar 2011

SHMT1 gene and folate deficiency increase risk for colon cancer

Offering a likely insight into how such cancers develop in humans - Cornell University researchers report they have identified a gene that increases the risk for colon cancer in laboratory mice when the animals' diets are deficient in folate.

30 Mar 2011

Intercept initiates OCA FLINT trial in patients with nonalcoholic steatohepatitis

Intercept Pharmaceuticals, Inc., has been informed by the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health that patient enrollment has started in a new clinical trial in patients with nonalcoholic steatohepatitis, which will evaluate Intercept's first-in-class farnesoid X receptor agonist obeticholic acid as a novel therapy for NASH.

30 Mar 2011

Metabolic Solutions initiates MSDC-0602 Phase 2a trial in patients with type 2 diabetes

Metabolic Solutions Development Company, a drug discovery and development company exploiting novel molecular targets to treat metabolic diseases, announced today that it has launched a Phase 2a trial for MSDC-0602, the company's second drug candidate for the treatment of type 2 diabetes.

30 Mar 2011

Researchers find patients with Alzheimer's have lower glucose utilization in brain

Researchers at Mount Sinai School of Medicine have found that patients with Alzheimer's disease have lower glucose utilization in the brain than those with normal cognitive function, and that those decreased levels may be detectable approximately 20 years prior to the first symptoms of Alzheimer's disease.

29 Mar 2011

SRI International, CDD receive NIAID grant to develop TB information repository

SRI International, an independent nonprofit research and development organization, and Collaborative Drug Discovery, provider of a web-based drug discovery software platform, announced that they have been awarded a grant to support the first year of a software development project focused on tuberculosis drug discovery efforts.

29 Mar 2011

A.P. Pharma fourth quarter revenue decreases to $1.6 million

A.P. Pharma, Inc., a specialty pharmaceutical company, today reported financial results for its fourth quarter and full year ended December 31, 2010 and provided a corporate update.

28 Mar 2011

Researchers identify enzyme biomarker that can diagnose early colon cancer

A research team at the University of Colorado Cancer Center has identified an enzyme that could be used to diagnose colon cancer earlier. It is possible that this enzyme also could be a key to stopping the cancer.

28 Mar 2011

Study demonstrates bisphenol A effect on animal embryonic development

Bisphenol A, whose impact on reproduction and development is the subject of numerous studies, induces anomalies in the inner ear of embryos of certain vertebrates.

25 Mar 2011

New discovery on fat metabolism in worms can lead to novel obesity treatment

Researchers exploring human metabolism at the University of California, San Francisco have uncovered a handful of chemical compounds that regulate fat storage in worms, offering a new tool for understanding obesity and finding future treatments for diseases associated with obesity.

25 Mar 2011

Columbia University, Sanofi-aventis collaborate to develop innovative diabetes medicines

Sanofi-aventis announced today a research collaboration with Columbia University Medical Center for the development of innovative diabetes medicines.

25 Mar 2011

Young adults with religious involvement more likely to become obese in middle-age

Could it be the potato salad? Young adults who frequently attend religious activities are 50 percent more likely to become obese by middle age as young adults with no religious involvement, according to new Northwestern Medicine research.

25 Mar 2011

Scientists discover hormone pathway that can lead to new diabetes treatment

Researchers at UT Southwestern Medical Center have discovered a hormone pathway that potentially could lead to new ways of treating type 1 diabetes independent of insulin, long thought to be the sole regulator of carbohydrates in the liver.

25 Mar 2011

Restricting sodium consumption important in lowering blood pressure among sedentary people

The more physically active you are, the less your blood pressure rises in response to a high-salt diet, researchers reported at the American Heart Association's Nutrition, Physical Activity and Metabolism/Cardiovascular Disease Epidemiology and Prevention 2011 Scientific Sessions.

24 Mar 2011

Low ghrelin levels in obese women may affect reproduction in female progeny

Levels of the hormone ghrelin are low in obese women and a recent study accepted for publication in Endocrinology, a publication of The Endocrine Society, reports that mice whose mothers had low ghrelin levels were less fertile due to a defect in implantation.

24 Mar 2011

American Heart Association: 81.8% of obese women underestimate their weight

Overweight and obese mothers and their children think they weigh less than their actual weight, according to research reported at the American Heart Association's Nutrition, Physical Activity and Metabolism/Cardiovascular Disease Epidemiology and Prevention 2011 Scientific Sessions.

24 Mar 2011

PFC exposure can lead to early menopause in women

A recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that higher levels of perfluorocarbons in the body are associated with increased odds of having experienced menopause in women between 42 and 64 years old. Women in this age group with high levels of PFCs also had significantly lower concentrations of estrogen when compared to women who had low levels of PFCs.

24 Mar 2011

Xenon founder receives Canada Wightman Award for leadership in medical science

Dr. Michael Hayden, a Xenon founder and Chief Scientific Officer, has received the Canada Gairdner Wightman Award for leadership in medical science in Canada.

23 Mar 2011

Metabolism News and Research

Latest Metabolism News and Research

Regulus obtains exclusive rights from NYU for miR-33a, 33b to treat metabolic diseases

Roche launces new GS GType HLA Primer Sets for HLA genotyping

DSP, Intercept enter license agreement for OCA

SHMT1 gene and folate deficiency increase risk for colon cancer

Intercept initiates OCA FLINT trial in patients with nonalcoholic steatohepatitis

Metabolic Solutions initiates MSDC-0602 Phase 2a trial in patients with type 2 diabetes

Researchers find patients with Alzheimer's have lower glucose utilization in brain

SRI International, CDD receive NIAID grant to develop TB information repository

A.P. Pharma fourth quarter revenue decreases to $1.6 million

Researchers identify enzyme biomarker that can diagnose early colon cancer

Study demonstrates bisphenol A effect on animal embryonic development

New discovery on fat metabolism in worms can lead to novel obesity treatment

Columbia University, Sanofi-aventis collaborate to develop innovative diabetes medicines

Young adults with religious involvement more likely to become obese in middle-age

Scientists discover hormone pathway that can lead to new diabetes treatment

Restricting sodium consumption important in lowering blood pressure among sedentary people

Low ghrelin levels in obese women may affect reproduction in female progeny

American Heart Association: 81.8% of obese women underestimate their weight

PFC exposure can lead to early menopause in women

Xenon founder receives Canada Wightman Award for leadership in medical science

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut