Metabolism News and Research

Latest Metabolism News and Research

Imaging PR status may help identify tumor response to endocrine therapy

Research published in the July issue of The Journal of Nuclear Medicine shows imaging progesterone receptor (PR) status also may be able to identify responders and nonresponders to endocrine therapy at an early stage.

3 Jul 2012

Researchers show how aggressive form of multiple myeloma resists chemotherapy

Researchers at Washington University School of Medicine in St. Louis have shown how an aggressive form of multiple myeloma resists chemotherapy.

3 Jul 2012

Vitamin D–calcium combo reduces mortality in elderly

The results of a meta-analysis of individual patient data show that vitamin D supplementation with calcium reduces mortality rates in the elderly.

2 Jul 2012

FDA approves Roche's new HIV viral load test

Roche announced today that a new HIV viral load test has been approved by the United States Food and Drug Administration (FDA) and will be commercially available in the US later this year.

2 Jul 2012

Transcranial direct current stimulation can enhance outcome of swallowing therapy for post-stroke dysphagia

After stroke, patients often suffer from dysphagia, a swallowing disorder that results in greater healthcare costs and higher rates of complications such as dehydration, malnutrition, and pneumonia.

2 Jul 2012

Janssen seeks accelerated FDA approval for bedaquiline to treat MDR-TB

Janssen Research & Development, LLC today announced it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) seeking accelerated approval for the use of the investigational drug bedaquiline (TMC207) as an oral treatment, to be used as part of combination therapy for pulmonary, multi-drug resistant tuberculosis (MDR-TB) in adults.

2 Jul 2012

Textile cooling pads to prevent neurological damage after successful resuscitation

Textile cooling pads are to be used in future to prevent neurological damage after successful resuscitation. The system developed by scientists from the Hohenstein Institute in Bönnigheim requires no electric power, making it ideal especially for first aid in case of cardiac arrest.

30 Jun 2012

Bees help understand connection between taste perception and metabolic syndromes

Scientists at Arizona State University have discovered that honey bees may teach us about basic connections between taste perception and metabolic disorders in humans. By experimenting with honey bee genetics, researchers have identified connections between sugar sensitivity, diabetic physiology and carbohydrate metabolism. Bees and humans may partially share these connections.

30 Jun 2012

$Epilepsy patients unaware of fracture risk$

Epilepsy patients unaware of fracture risk

Few patients with epilepsy are aware that taking anti-epileptic drugs puts them at increased risk for falls and fractures, report researchers.

29 Jun 2012

RUB biologists deliberately transform spinal cord stem cells into immature nerve cells

RUB biologists have deliberately transformed stem cells from the spinal cord of mice into immature nerve cells. This was achieved by changing the cellular environment, known as the extracellular matrix, using the substance sodium chlorate.

29 Jun 2012

Study reveals technique that allows scientists to watch lipid metabolism in live zebrafish

In mammals, most lipids are absorbed into the body via the small intestine. The complexity of the cells and fluids that inhabit this organ make it very difficult to study in a laboratory setting. New research from Carnegie's Steven Farber, James Walters and Jennifer Anderson reveals a technique that allows scientists to watch lipid metabolism in live zebrafish. This method enabled them to describe new aspects of lipid absorption that could have broad applications for human health.

29 Jun 2012

Study explains why memory improves on a high-DHA diet

We've all heard that eating fish is good for our brains and memory. But what is it about DHA, an omega-3 fatty acid found in fish, that makes our memory sharper? Medical researchers at the University of Alberta discovered a possible explanation and just published their findings in the peer-reviewed journal Applied Physiology, Nutrition, and Metabolism.

29 Jun 2012

New drug for Type 2 diabetes results in less hypoglycaemia, less weight gain and perhaps less cardiovascular risk for patients

A new drug could offer significant advantages over existing treatments for Type 2 diabetes patients who don’t respond to metformin, the most commonly prescribed initial drug treatment for the disease. The new drug, linagliptin, results in significantly less weight gain than the most common second-line treatments currently used, and may even carry a smaller risk of cardiovascular events such as heart attack and stroke, according to an Article published Online First in The Lancet.

29 Jun 2012

Millennium introduces novel pharmacogenetic testing

Millennium Laboratories, the leading research-based clinical diagnostic company dedicated to improving the lives of people suffering from pain, announced today the introduction of Millennium Pharmacogenetic Testing.

29 Jun 2012

Data from Infinity’s IPI-145 pre-clinical study on inflammatory diseases

Infinity Pharmaceuticals, Inc. today reported preclinical data for IPI-145, the company's oral inhibitor of phosphoinositide-3-kinase (PI3K)-delta and PI3K-gamma. The data demonstrate potent PI3K-delta and -gamma inhibition in biochemical, cellular and whole blood assays and activity in multiple preclinical models of inflammatory disease, including rheumatoid arthritis and asthma.

28 Jun 2012

Study suggests adverse role for BclI polymorphism in obesity and insulin resistance

A large study in people at risk of diabetes has found a direct association between the presence of a small genetic alteration in a hormone receptor and increased body fat and insulin resistance. The results, to be presented Tuesday at The Endocrine Society's 94th Annual Meeting in Houston, suggest an adverse role for a previously described genetic variant, the BclI polymorphism.

28 Jun 2012

Health Canada approves AutoGenomics’ INFINITI PGx testing system

AutoGenomics, a leader in providing automated, molecular microarray testing solutions, announced today that they have received their first Health Canada Medical Device Class III approvals for their automated INFINITI Pharmacogenomic (PGx) testing system.

28 Jun 2012

$Chinese herbal preparation reduces fragility fractures$

Chinese herbal preparation reduces fragility fractures

Herbal Fufang – a multi-herbal preparation used in traditional Chinese medicine –increases bone mineral density and reduces fragility fractures in postmenopausal women, Chinese researchers report.

27 Jun 2012

Protein kinase A activated in the nucleus as well as the cytoplasm

Using a new tool allowing proteins in a living cell to be manipulated in real time, researchers at Johns Hopkins have stumbled across the answer to a longstanding debate about where and how a certain protein is turned on in the cell. Reporting in the February 2012 issue of Nature Chemical Biology, scientists show that protein kinase A is also activated in the nucleus rather than inside the cell’s body, a challenge to traditional beliefs.

27 Jun 2012

EU agenda focusses on lifesyle changes towards healthy diets and improved physical activity

A common Strategic Research Agenda of 22 countries in Europe focusses on lifesyle changes towards healthy diets and improved physical activity. Biomarker research, nutrigenomics, perzonalized food supplies and the prevention of chronic lifestyle related diseases are key-fields of the Joint Programming Inititative " A Healthy Diet for a Healthy Life."

27 Jun 2012

Metabolism News and Research

Latest Metabolism News and Research

Imaging PR status may help identify tumor response to endocrine therapy

Researchers show how aggressive form of multiple myeloma resists chemotherapy

Vitamin D–calcium combo reduces mortality in elderly

FDA approves Roche's new HIV viral load test

Transcranial direct current stimulation can enhance outcome of swallowing therapy for post-stroke dysphagia

Janssen seeks accelerated FDA approval for bedaquiline to treat MDR-TB

Textile cooling pads to prevent neurological damage after successful resuscitation

Bees help understand connection between taste perception and metabolic syndromes

Epilepsy patients unaware of fracture risk

RUB biologists deliberately transform spinal cord stem cells into immature nerve cells

Study reveals technique that allows scientists to watch lipid metabolism in live zebrafish

Study explains why memory improves on a high-DHA diet

New drug for Type 2 diabetes results in less hypoglycaemia, less weight gain and perhaps less cardiovascular risk for patients

Millennium introduces novel pharmacogenetic testing

Data from Infinity’s IPI-145 pre-clinical study on inflammatory diseases

Study suggests adverse role for BclI polymorphism in obesity and insulin resistance

Health Canada approves AutoGenomics’ INFINITI PGx testing system

Chinese herbal preparation reduces fragility fractures

Protein kinase A activated in the nucleus as well as the cytoplasm

EU agenda focusses on lifesyle changes towards healthy diets and improved physical activity

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy