Metabolism News and Research

Latest Metabolism News and Research

Combination of LIVALO and itraconazole drugs shows no adverse reactions

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2 Sep 2009

Strategy to enhance diabetes management across Canada

Research being driven by The University of Western Ontario that will enhance diabetes management across Canada recently received support from two of Canada's leading pharmaceutical companies in the form of a $500,000 contribution.

2 Sep 2009

The Kyoto Heart study shows positive effect of valsartan on cardiovascular outcome

The KYOTO HEART Study, which took place in Japan between January 2004 and January 2009, shows that the addition of valsartan to conventional antihypertensive treatment to improve blood pressure control is associated with an improved cardiovascular outcome in Japanese hypertensive patients at high risk of CVD events.

2 Sep 2009

Study reveals that valsartan prevents cardiovascular events in high-risk hypertensive Japanese patients

2 Sep 2009

Genes that regulate the energy consumption of cells have a different structure and expression in diabetics

Genes that regulate the energy consumption of cells have a different structure and expression in type II diabetics than they do in healthy people, according to a new study from the Swedish medical university Karolinska Institutet published in Cell Metabolism.

2 Sep 2009

Research reveals that dramatic maternal weight loss prevents obesity in their children

Adolescent and young children of obese mothers who underwent weight-loss surgery prior to pregnancy have been found to have a lower prevalence of obesity and significantly improved cardio-metabolic markers when compared to siblings born before the same obese mothers had weight-loss surgery. This new study has been accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

2 Sep 2009

Grant awarded to two researchers to study the role of GLP-1 in people at risk for or with diabetes

The American Diabetes Association Research Foundation has selected two scientists, University of Virginia Health System researcher Zhenqi Liu, MD, and Stanford University School of Medicine researcher Gerald Reaven, MD, to receive the American Diabetes Association-Novo Nordisk Clinical/Translational Research Award. This $1.2 million grant program supports efforts to study the effects of intestinal hormones, such as glucagon-like peptide-1 (GLP-1), on obesity and pre-diabetes, two risk factors for type 2 diabetes and cardiovascular disease.

2 Sep 2009

Scientists shed light on the relationship between hypertension and obesity

Some of the first information about how fat causes hypertension have been identified by researchers who say the findings should one day help identify which obese people - and maybe some thin ones too - are at risk for hypertension and which drugs would work best for them.

2 Sep 2009

Hexokinase 2 gene highly expressed in brain metastasis in breast cancer patients

Researchers at the National Cancer Institute have identified a gene that may play a role in breast cancer metastasis to the brain, according to a report in Molecular Cancer Research, a journal of the American Association for Cancer Research.

2 Sep 2009

Paper discussing the mechanism of the selective TGR5 agonist INT-777 published in Cell Metabolism

Bile acids are known to be key regulators of lipid, glucose and overall energy metabolism. Bile acid activation of the G protein-coupled receptor TGR5 has been shown to induce energy expenditure in muscle and brown fat, thereby conferring resistance to weight gain.

2 Sep 2009

High-density lipoprotein cholesterol concentrations increased in patients treated with LIVALO

New data presented today showed that in patients treated with LIVALO (pitavastatin), high-density lipoprotein cholesterol (HDL-C) concentrations increased, and nearly three-fourths of patients attained low-density lipoprotein cholesterol (LDL-C) targets, with results sustained over 52 weeks.

2 Sep 2009

Weight-loss surgery prior to pregnancy results in lower prevalence of obesity in children

1 Sep 2009

New study reveals that moderate aerobic exercise improves insulin sensitivity in obese adolescents

A moderate aerobic exercise program, without weight loss, can improve insulin sensitivity in both lean and obese sedentary adolescents, according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). Insulin is a hormone produced in the pancreas that permits glucose to enter cells to be used for energy or stored for future use by the body.

1 Sep 2009

NASDAQ Stock Market issues noncompliance letter to Encorium Group

Encorium Group, Inc. (Nasdaq: ENCO), a full service multinational clinical research organization (CRO) conducting studies in over 30 countries for many of the world's leading pharmaceutical and biotechnology companies, today announced that on August 25, 2009, it received a letter from The NASDAQ Stock Market notifying the Company that, based on its Form 10-Q for the period ended June 30, 2009, NASDAQ has determined that the Company's stockholders' equity does not comply with the minimum $2.5 million stockholders' equity requirement for continued listing on The NASDAQ Capital Market as required by NASDAQ Marketplace Rule 5550(b)(1).

1 Sep 2009

Study provides insights into genes that help maintain youthfulness of the skin

In the new print issue of Nature Genetics, scientists in Singapore and Germany report that mutations in the PYCR1 gene cause the rare genetic condition that results in premature skin aging and that is known as "wrinkly skin syndrome."

1 Sep 2009

FDA approves the usage of Valcyte for preventing CMV disease in pediatric patients

Roche announced today that the U.S. Food and Drug Administration (FDA) has approved Valcyte(R) (valganciclovir hydrochloride) for the prevention of cytomegalovirus (CMV) disease in pediatric kidney and heart transplant patients (4 months to 16 years of age) at high risk of developing CMV disease.

31 Aug 2009

Springer signs agreement with The Endocrine Society to co-publish a new journal

Springer, one of the leading publishers in the fields of science, technology and medicine, has signed an agreement with The Endocrine Society to co-publish a new journal, Hormones & Cancer, starting in January 2010.

28 Aug 2009

Fatostatin lowers the activity of genes associated with cholesterol synthesis

A small molecule earlier found to have both anti-fat and anti-cancer abilities works as a literal turnoff for fat-making genes, according to a new report in the August 28th issue of the journal Chemistry and Biology, a Cell Press journal.

27 Aug 2009

Rutgers University Professor receives $3.5 million MERIT Award from NIH

Rutgers University Professor Dipak Sarkar has received a $3.5 million MERIT Award from the National Institutes of Health (NIH) to continue researching the damaging effects of alcohol on the nervous systems of the unborn.

27 Aug 2009

Waters exhibits the SYNAPT G2 system at the 18th International Mass Spectrometry Conference in Europe

Waters Corporation (NYSE: WAT) today exhibited for the first time in Europe the Waters((R)) SYNAPT(TM) G2 a system offering scientists greater power, versatility and speed at the 18(th) International Mass Spectrometry Conference (IMSC). Rounding out its display of mass spectrometry (MS) and UltraPerformance Liquid Chromatography (UPLC((R)))/MS systems at IMSC will be Waters Xevo(TM) family of tandem quadrupole and time-of-flight mass spectrometers noted for their ease-of-use and versatility.

27 Aug 2009

Metabolism News and Research

Latest Metabolism News and Research

Combination of LIVALO and itraconazole drugs shows no adverse reactions

Strategy to enhance diabetes management across Canada

The Kyoto Heart study shows positive effect of valsartan on cardiovascular outcome

Study reveals that valsartan prevents cardiovascular events in high-risk hypertensive Japanese patients

Genes that regulate the energy consumption of cells have a different structure and expression in diabetics

Research reveals that dramatic maternal weight loss prevents obesity in their children

Grant awarded to two researchers to study the role of GLP-1 in people at risk for or with diabetes

Scientists shed light on the relationship between hypertension and obesity

Hexokinase 2 gene highly expressed in brain metastasis in breast cancer patients

Paper discussing the mechanism of the selective TGR5 agonist INT-777 published in Cell Metabolism

High-density lipoprotein cholesterol concentrations increased in patients treated with LIVALO

Weight-loss surgery prior to pregnancy results in lower prevalence of obesity in children

New study reveals that moderate aerobic exercise improves insulin sensitivity in obese adolescents

NASDAQ Stock Market issues noncompliance letter to Encorium Group

Study provides insights into genes that help maintain youthfulness of the skin

FDA approves the usage of Valcyte for preventing CMV disease in pediatric patients

Springer signs agreement with The Endocrine Society to co-publish a new journal

Fatostatin lowers the activity of genes associated with cholesterol synthesis

Rutgers University Professor receives $3.5 million MERIT Award from NIH

Waters exhibits the SYNAPT G2 system at the 18th International Mass Spectrometry Conference in Europe

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Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer