Metabolism News and Research

Latest Metabolism News and Research

The interplay between immunity, the nervous system, and microbiota

Researchers review the influence of the gut microbiota on neural and immune network

15 Aug 2023

Epigenetic manipulation may improve breast cancer treatment responses

Researchers explore the possibility of increasing TROP2 ADC activity by enhancing the expression of TROP2 on cancer cells.

15 Aug 2023

Newly discovered protein kinase shows promise for establishing future obesity and diabetes treatments

Researchers used genetically modified animal models to investigate the role of the newly discovered Traf2- and NCK-interacting protein kinase (TNIK) in obesity and metabolic dysfunction.

15 Aug 2023

The impact of oat consumption on the gut microbiota

The relationship between the gut microbiome and oat consumption.

15 Aug 2023

Genetic determinants of retinol circulation and their impact on health

The genetic architecture of circulating retinol.

15 Aug 2023

Can fasting benefit individuals with diabetes?

Fasting and its effect on diabetes.

15 Aug 2023

A computational model identifies metabolites associated with Parkinson's disease

Researchers identify significant metabolites involved in the development and progression of Parkinson’s disease.

15 Aug 2023

Pairing top-down and bottom-up approaches to gain insights into the origin of life

Despite decades of progress, the origin of life remains one of the great unsolved problems in science.

14 Aug 2023

Do sugar-sweetened carbonated beverages increase depression risks?

Researchers employed a longitudinal analysis of data to investigate the association between the consumption of sugar-sweetened carbonated beverages and the risk of depression.

14 Aug 2023

Unveiling α1-AR secrets: breakthrough structures and targeted drug design

Researchers explored the structural basis of agonist specificity of α1A-adrenergic receptors (α1-ARs).

14 Aug 2023

Researchers design one-step procedure for improving effective of adoptive cell immunotherapy against solid tumors

Researchers developed a one-step method to engineer multifunctional M1 phenotype macrophages.

14 Aug 2023

Study reveals the health and dietary benefits of consuming cardamom

A new study by Texas A&M AgriLife revealed a range of health and dietary benefits of consuming cardamom, including increased appetite, fat loss and inflammation reduction, making the spice a "superfood."

13 Aug 2023

Glucokinase activators induce hepatic lipid accumulation in mice with high-fat diet

The researchers demonstrated that glucokinase activation was effective in lowering blood glucose in mice with high-fat diet-induced obesity, while it potentially raised the risk of increasing hepatic lipid accumulation that triggered the PERK-UPR pathway.

11 Aug 2023

CRISPR/sgRNA-SAM therapy: a potential breakthrough for Parkinson's disease?

Researchers utilize the CRISPR-Cas9 system to induce the synthesis of dopamine (DA) in the brains of a rat model for Parkinson’s disease.

11 Aug 2023

Personalized exercise testing may be more effective for fat loss

The best heart rate for burning fat differs for each individual and often does not align with the "fat burning zone" on commercial exercise machines, Icahn School of Medicine at Mount Sinai researchers report.

11 Aug 2023

A drug for heart conditions improves efficacy of melanoma therapies

A collaborative study undertaken by the Navarrabiomed Biomedical Research Center (Pamplona, Navarre), the Institute of Neurosciences CSIC-UMH (Sant Joan d'Alacant, Valencian Community) and IRB Barcelona (Barcelona, Catalonia) shows that the administration of ranolazine, a drug currently used to treat heart conditions, improves the efficacy of current therapies for melanoma, in mouse models of this disease.

10 Aug 2023