Metabolism News and Research

Latest Metabolism News and Research

Leucine deficient diet has antidepressant effects on chronic restraint stress-induced depression-like behaviors

Depression is a leading cause of disability around the world and contributes greatly to the global burden of disease.

6 Jun 2023

Umbrella review assesses the association between artificially sweetened beverages and health outcomes

A recent umbrella review evaluated the associations between ASBs and health outcomes.

6 Jun 2023

How does tirzepatide stimulate insulin secretion?

Tirzepatide, a drug approved for diabetes and on the fast track for approval as a weight loss therapy, works through a unique ability to activate two different mechanisms the body uses to control insulin secretion and energy balance, Duke Health researchers report.

6 Jun 2023

How lipid metabolites in the gut aid in regulatory T-cell differentiation

Researchers describe the Treg-cell-inducing activity of lipid extracts from the feces of specific-pathogen-free mice.

6 Jun 2023

Protecting the heart during menopausal transition may help protect brain health

The research, published in the journal Alzheimer's & Dementia, is further evidence that the menopause transition is a particularly important time for women and their doctors to pay attention to heart health, in turn protecting their brain health.

5 Jun 2023

Cure Mito Foundation releases the first-of-its-kind online resource about Leigh syndrome

The Cure Mito Foundation, a parent-led organization dedicated to advancing research and treatments for Leigh syndrome, has launched the first-of-its-kind online resource about Leigh syndrome, the most common type of pediatric mitochondrial disease.

5 Jun 2023

Freiburg researchers gain new insights into metabolic processes in the kidney

Researchers at the Faculty of Medicine at the University of Freiburg have gained significant new insights into metabolic processes in the kidney.

5 Jun 2023

Study offers the most comprehensive archive of cellular, molecular features involved in psoriatic disease

Beneath and beyond the reddish, flaky lesions that form in the skin of those with psoriasis, mild and severe forms of the disease can be told apart by the activity of key cells and signaling pathways, a new study shows.

2 Jun 2023

Sleep-disordered breathing in cognitively unimpaired amyloid-positive individuals may exacerbate neurodegeneration in medial temporal lobe subregions

A new study investigated the link between SDB severity and the volume of medial temporal lobe (MTL) substructures. In addition, it also evaluated the association between SDB and MTL subregions volumes with episodic memory performance.

2 Jun 2023

Juicy findings: Chinese consumers embrace fruit peel delights, scientists examine nutritional value and pesticide concerns

Research explores the consumption of fruit peels by Chinese consumers, highlighting their nutritional value and pesticide residues. It provides insights into methods of pesticide detection and removal, as well as the physiological benefits of fruit peels, aiming to guide informed consumption and contribute to further research in this area.

1 Jun 2023

RNA regulatory mechanism could be targeted to slow AD progression mediated by stress granules

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 10, entitled, "Stress granules sequester Alzheimer's disease-associated gene transcripts and regulate disease-related neuronal proteostasis."

1 Jun 2023

Study suggests licorice-derived liquiritigenin has breast cancer prevention potential for high-risk postmenopausal women

Researchers evaluated the potential of three licorice (Glycyrrhiza) species, i.e., G. glabra (GG), G. uralensis (GU), and G. infata (GI), and hops (Humulus lupulus), and their main bioactive polyphenols, to prevent breast malignancy.

1 Jun 2023

Peptidomimetic antibiotics may be effective against resistant bacteria

Health professionals are in urgent need of new antibiotics to tackle resistant bacteria. Researchers at the University of Zurich and the company Spexis have now modified the chemical structure of naturally occurring peptides to develop antimicrobial molecules that bind to novel targets in the bacteria's metabolism.

1 Jun 2023

Study sheds light on metabolic enzymes and processes essential for DNA damage repair

In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research.

1 Jun 2023

Multi-ethnic genome study unlocks new genetic links to health conditions

Research explores the genetic architecture of circulating metabolites, uncovering novel variant-metabolite associations and validating previous findings. It provides insights into the genetic contribution to metabolite levels and potential implications for human disease.

31 May 2023

Unique combination of intestinal bacteria in Japanese centenarians may be the key to long life

We are pursuing the dream of eternal life. We fast to stay healthy. And each year, we spend billions of kroner on treatment to make sure we stay alive. But some people turn 100 years old all by themselves. Why is that?

31 May 2023

A simple tweak to first meal of the day may benefit people with Type 2 diabetes

An international team, led by UBC Okanagan researchers, suggests a simple tweak to the first meal of the day might help people living with Type 2 diabetes (T2D) better control their blood sugar levels.

31 May 2023

Babies experiencing hypoxia due to sleep apnea tend to develop hypertension in adulthood

Newborn babies who experience low levels of oxygen in their body tissues (hypoxia) due to sleep apnea, for example, tend to develop respiratory problems and hypertension (high blood pressure) in adulthood, and these problems may persist for the rest of their lives.

31 May 2023

Moderate-protein diet improves metabolic health in both young and middle-aged mice

Consuming nutritious food can improve metabolic health and delay aging. But what are the appropriate quantities of dietary macronutrients that can help achieve this? To answer this, researchers from Japan fed isocaloric diets with varying amounts of protein to young and middle-aged male mice.

31 May 2023

Environmental enrichment may reduce early accumulation of amyloid plaques in Alzheimer's mouse model

About two-thirds of the risk for Alzheimer's disease (AD) is thought to arise from genetic influences, but about a third could be influenced by environment and lifestyle, opening the door for behavioral interventions that could delay or prevent pathophysiological changes that occur with AD.

31 May 2023

Metabolism News and Research

Latest Metabolism News and Research

Leucine deficient diet has antidepressant effects on chronic restraint stress-induced depression-like behaviors

Umbrella review assesses the association between artificially sweetened beverages and health outcomes

How does tirzepatide stimulate insulin secretion?

How lipid metabolites in the gut aid in regulatory T-cell differentiation

Protecting the heart during menopausal transition may help protect brain health

Cure Mito Foundation releases the first-of-its-kind online resource about Leigh syndrome

Freiburg researchers gain new insights into metabolic processes in the kidney

Study offers the most comprehensive archive of cellular, molecular features involved in psoriatic disease

Sleep-disordered breathing in cognitively unimpaired amyloid-positive individuals may exacerbate neurodegeneration in medial temporal lobe subregions

Juicy findings: Chinese consumers embrace fruit peel delights, scientists examine nutritional value and pesticide concerns

RNA regulatory mechanism could be targeted to slow AD progression mediated by stress granules

Study suggests licorice-derived liquiritigenin has breast cancer prevention potential for high-risk postmenopausal women

Peptidomimetic antibiotics may be effective against resistant bacteria

Study sheds light on metabolic enzymes and processes essential for DNA damage repair

Multi-ethnic genome study unlocks new genetic links to health conditions

Unique combination of intestinal bacteria in Japanese centenarians may be the key to long life

A simple tweak to first meal of the day may benefit people with Type 2 diabetes

Babies experiencing hypoxia due to sleep apnea tend to develop hypertension in adulthood

Moderate-protein diet improves metabolic health in both young and middle-aged mice

Environmental enrichment may reduce early accumulation of amyloid plaques in Alzheimer's mouse model

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering