Metabolomics News and Research

Latest Metabolomics News and Research

Study reveals chromosome-level changes that relate to drug resistance in melanoma

Precision therapies targeting melanoma and other cancers have improved patient survival, but tumors often stop responding to drugs, and recent studies point to changes in DNA – both inside and outside chromosomes – as a driving factor in tumor genesis as well as in treatment resistance.

20 Dec 2021

Higher intake of plant-based foods could help reduce the risk of cognitive decline due to aging

A diet rich in plant products reduces the risk of cognitive impairment and dementia in the elderly. This is the result of a study by the Biomarkers and Nutritional Food Metabolomics Research Group of the Faculty of Pharmacy and Food Sciences of the University of Barcelona and the CIBER on Frailty and Healthy Aging.

9 Dec 2021

Study uncovers differences in one-carbon and energy metabolism between episodic, chronic depression

A study carried out in the University of Eastern Finland discovered differences in one-carbon and energy metabolism between episodic and chronic depression.

9 Dec 2021

Study uncovers new mechanism to explain how obesity jeopardizes the functions of skeletal muscle

A decline in metabolism and endurance of skeletal muscle is commonly observed in obese patients, but the underlying mechanism is not well-understood.

30 Nov 2021

Johns Hopkins receives $20 million grant to develop technologies for healthy aging

Johns Hopkins has received a $20 million grant from the National Institute on Aging that will spur the development of artificial intelligence devices (AI) to improve the health of older adults and help them live independently for longer — a relatively untapped use of this technology.

11 Nov 2021

Taking lessons in molecular therapeutics from earthworms to combat COVID

Scientists were interested in further investigating the defense mechanism of earthworms in an effort to discover therapeutic solutions against SARS-CoV-2.

27 Oct 2021

Polyphenol-rich diet improves the intestinal permeability in older adults

The increase of intestinal permeability is associated with factors such as ageing, food allergies and intolerances and unhealthy diets.

26 Oct 2021

UC Davis researchers publish the first atlas of metabolites in the mouse brain

The first atlas of metabolites in the mouse brain has been published by a team led by UC Davis researchers.

18 Oct 2021

Researchers identify new biomarker for severe COVID-19

During the pandemic, it has become increasingly evident that people with cardiovascular disease and obesity are at a much higher risk of developing very severe, even fatal COVID-19 disease.

8 Oct 2021

Metabolic and immune markers as tools for risk stratification and monitoring in COVID-19

In a new study posted to the medRxiv* server scientists from Weil Cornell University and Stony Brook University in New York attempted to identify the metabolic and immune markers associated with severe COVID-19 disease using high-throughput targeted nuclear magnetic resonance (NMR) spectroscopy and high-dimensional flow cytometry. This will facilitate risk stratification, monitoring, and therapeutic interventions in COVID-19 patients.

14 Sep 2021

Study finds accumulation of common therapeutic drugs by gut bacteria

Common medications can accumulate in gut bacteria, a new study has found, altering bacterial function and potentially reducing the effectiveness of the drug.

8 Sep 2021

Newly identified mechanism can accelerate the development of STING-activating drugs using imaging

A new study from scientists at the UCLA Jonsson Comprehensive Cancer Center found that emerging drugs that activate the protein STING, a well-established regulator of immune cell activation, substantially alter the activity of metabolic pathways responsible for generating the nucleotide building blocks for DNA.

7 Sep 2021

Research reveals a previously unknown role for a key transcription regulator linked to cancer

CTCF is a transcription factor that has been a research target due to its role in regulating a critical oncogene called MYC.

7 Sep 2021

Weill Cornell receives NIH support to advance TB research

Tuberculosis (TB) is one of the deadliest infectious diseases in history and one of the few that naturally infects only humans.

4 Sep 2021

New MOGONET outperforms existing supervised multi-omics integrative analysis approaches

Genomics, proteomics, metabolomics, transcriptomics -- rapid advances in high-throughput biomedical technologies has enabled the collection of data with unprecedented detail from the growing number of omics.

27 Aug 2021

Child with Bachmann-Bupp Syndrome successfully treated in just 16 months

Diagnosing a rare medical condition is difficult. Identifying a treatment for it can take years of trial and error. In a serendipitous intersection of research expertise, an ill patient in this case a child and innovative technology, Bachmann-Bupp Syndrome has gone from a list of symptoms to a successful treatment in just 16 months.

20 Jul 2021

Metabolomics: The Individual Metabolic Profile is the Key to Personalized Medicine

The study of these unique substances in each of us paves the way for a revolution in the treatment and prevention of diseases, allowing for early diagnosis and increasingly targeted pharmacological treatments.

From Bruker BioSpin - NMR, EPR and Imaging 14 Jul 2021

USF receives $69.9 Million NIH funding to continue study on type 1 diabetes

The National Institutes of Health has awarded the University of South Florida total expected funds of $69.9 million over the next four years to continue the follow-up of study participants in The Environmental Determinants of Diabetes in The Young (TEDDY) consortium.

13 Jul 2021

Untargeted metabolomics profiling can improve diagnosis of metabolic disorders in newborns

A team led by researchers at Baylor College of Medicine found that a screening method known as untargeted metabolomics profiling can improve the diagnostic rate for inborn errors of metabolism, a group of rare genetic conditions, by about seven-fold when compared to the traditional metabolic screening approach.

12 Jul 2021

Can saliva metabolomics predict COVID-19 severity?

New research suggests that saliva metabolomics may be able to help prognosticate disease severity in COVID-19 positive individuals.

9 Jul 2021