Metabolomics News and Research

Latest Metabolomics News and Research

Newly discovered protein kinase shows promise for establishing future obesity and diabetes treatments

Researchers used genetically modified animal models to investigate the role of the newly discovered Traf2- and NCK-interacting protein kinase (TNIK) in obesity and metabolic dysfunction.

15 Aug 2023

The mechanisms of triptan using metabolomics and transcriptomics in spontaneous migraine attacks

Researchers discuss the mechanisms of triptans for the treatment of spontaneous migraine attacks by using transcriptomics and metabolomics.

3 Aug 2023

Study highlights metabolite targets for depression prevention that are easily modifiable through diet interventions

Researchers used a UHPLC and mass spectrometry-based Metabolon platform to identify and characterize circulating metabolites associated with depression.

1 Aug 2023

Researchers seek to understand the Achilles' heel of insulin pump technology

Since the insulin pump started widespread use in the early 1980s, it's become the option of choice for type 1 diabetes patients to manage their glucose levels in a way that doesn't require testing their blood sugar and injecting insulin multiple times daily.

27 Jul 2023

Lab-on-a-chip technologies offer new ways to assess stored red blood cells

Ziya Isiksacan, PhD, a research fellow in the Center for Engineering in Medicine and Surgery (CEMS) is the lead author, and Osman Berk Usta, PhD, an investigator in the CEMS at Massachusetts General Hospital and an associate professor of Surgery at Harvard Medical School, is the senior author of a new study published in PNAS, Assessment of Stored Red Blood Cells Through Lab-on-a-Chip Technologies for Precision Transfusion Medicine.

26 Jul 2023

Mediterranean diet may improve response to physical exercise in hospitalized older adults

Hospitalized older people who do not follow a Mediterranean diet could benefit from a physical exercise program to prevent hospitalization-associated disability, that is, loss of skills in daily-life activities.

26 Jul 2023

Meta-analysis confirms 17 key metabolites as strong predictors of gout

Researchers summarized the use of metabolomics to detect metabolites in gout patients.

18 Jul 2023

New study links perfluoroalkyl substance exposure to childhood asthma phenotypes

Study evaluated the effects of exposure to perfluoroalkyl substances on asthma phenotypes.

13 Jul 2023

Elucidating the role of the gut-brain-axis in autism

The study investigates the relationship between the gut and the brain in autism spectrum disorder (ASD), identifying microbial profiles and metabolic products associated with ASD phenotypes, dietary patterns, and inflammation. The findings provide insights into the role of the gut-brain axis in ASD and its potential impact on understanding and managing the disorder.

28 Jun 2023

Novel technology helps analyze tumor growth in another dimension

Tumors are composed of rapidly multiplying cancer cells. Understanding which biochemical processes fuel their relentless growth can provide hints at therapeutic targets.

2 Jun 2023

Study sheds light on metabolic enzymes and processes essential for DNA damage repair

In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research.

1 Jun 2023

Multi-ethnic genome study unlocks new genetic links to health conditions

Research explores the genetic architecture of circulating metabolites, uncovering novel variant-metabolite associations and validating previous findings. It provides insights into the genetic contribution to metabolite levels and potential implications for human disease.

31 May 2023

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to this year's recipient of the Pittsburgh Analytical Chemistry Award, Neil Kelleher, about his work in top-down proteinomics.

From Pittcon 26 May 2023

Mays Cancer Center conducts clinical trial combining two drugs in patients with recurrent, high-grade glioblastoma

The Mays Cancer Center at The University of Texas Health Science Center at San Antonio recently conducted a clinical trial combining two drugs in patients with recurrent, high-grade glioblastoma (GBM).

24 May 2023

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Research unveils the significance of uridine as a metabolic fuel in pancreatic ductal adenocarcinoma (PDA) cells under glucose-deprived conditions. Uridine utilization, mediated by uridine phosphorylase 1 (UPP1), supports redox balance, survival, and proliferation in PDA, highlighting its potential as a novel therapeutic target in the treatment of this resistant cancer.

23 May 2023

Metabolomics News and Research

Latest Metabolomics News and Research

Newly discovered protein kinase shows promise for establishing future obesity and diabetes treatments

The mechanisms of triptan using metabolomics and transcriptomics in spontaneous migraine attacks

Study highlights metabolite targets for depression prevention that are easily modifiable through diet interventions

Researchers seek to understand the Achilles' heel of insulin pump technology

Lab-on-a-chip technologies offer new ways to assess stored red blood cells

Mediterranean diet may improve response to physical exercise in hospitalized older adults

Meta-analysis confirms 17 key metabolites as strong predictors of gout

New study links perfluoroalkyl substance exposure to childhood asthma phenotypes

Elucidating the role of the gut-brain-axis in autism

Novel technology helps analyze tumor growth in another dimension

Study sheds light on metabolic enzymes and processes essential for DNA damage repair

Multi-ethnic genome study unlocks new genetic links to health conditions

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

Mays Cancer Center conducts clinical trial combining two drugs in patients with recurrent, high-grade glioblastoma

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Novel ingestible device enables non-invasive profiling of the gut microbiome, proteome, and metabolome

A machine-learning approach for the early diagnosis of Parkinson's disease

Specially designed capsule gives a fuller picture of normal digestion in healthy people

New AI tool shows early promise in detecting Parkinson's disease years before symptom onset

Cannabis product authenticity: a metabolomic big data approach

Omics eBook

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy