Neuroblastoma News and Research

Latest Neuroblastoma News and Research

Physician-researcher to lead pediatric Dream Team to create new treatments for childhood cancers

A physician-researcher from The Children's Hospital of Philadelphia will lead the first-ever pediatric "Dream Team" solely focused on creating new treatments for the most challenging childhood cancers.

8 Apr 2013

Scientists develop new cancer immunotherapy treatment for children with high-risk solid tumors

Recently, research using adoptive T-cell immunotherapy in blood cancers have shown success, most notably in the case of a seven-year-old girl whose leukemia went into remission using altered T-cells and a disabled HIV virus.

4 Apr 2013

Three institutions partner to create research breakthroughs in children's health

Virginia Tech, Children's National Medical Center, and the George Washington University have partnered in a unique program to create research breakthroughs in children's health.

4 Apr 2013

CHOP expert to receive Pediatric Oncology Award from ASCO

The American Society of Clinical Oncology today announced it will confer one of its highest awards on pediatric oncologist Garrett M. Brodeur, M.D., of the Cancer Center at The Children's Hospital of Philadelphia.

16 Mar 2013

Pediatric cancer charities collaborate to create new treatments for children with neuroblastoma

Solving Kids' Cancer, along with U.K.-based charities Neuroblastoma Alliance UK, J-A-C-K, and other European organizations have aligned forces to improve access to promising clinical trials for children with high-risk neuroblastoma in North America, the U.K. and Europe.

5 Mar 2013

UHCC researchers identify role of RSK2 protein in cancer cell migration

Researchers at the University of Hawai'i Cancer Center have uncovered a novel mechanism that may lead to more selective ways to stop cancer cells from spreading. Associate Professor Joe W. Ramos PhD, a cancer biologist at the UH Cancer Center and his team have identified the role of the protein RSK2 in cancer cell migration, part of the process of cancer metastasis.

27 Feb 2013

Researchers determine that neuroblastoma is sensitive to BET bromodomain inhibitors

Neuroblastoma, the most common malignant tumor of early childhood, is frequently associated with the presence of MYCN amplification, a genetic biomarker associated with poor prognosis. Researchers have determined that tumors containing MYCN amplification are sensitive to a new class of drugs, BET bromodomain inhibitors.

22 Feb 2013

Glimmer of hope for imatinib-resistant GIST

The monoclonal antibody SR1 can significantly inhibit gastrointestinal stromal tumor cell growth, report researchers in the Proceedings of the National Academy of Sciences.

7 Feb 2013

Genome sequencing data gives important clues on cancer

Genome sequencing data once regarded as junk is now being used to gain important clues to help understand disease.

25 Jan 2013

Study refocuses on how neuroblastoma tumors evolve in response to medicine and other factors

An extensive genomic study of the childhood cancer neuroblastoma reinforces the challenges in treating the most aggressive forms of this disease. Contrary to expectations, the scientists found relatively few recurrent gene mutations—mutations that would suggest new targets for neuroblastoma treatment. Instead, say the researchers, they have now refocused on how neuroblastoma tumors evolve in response to medicine and other factors.

21 Jan 2013

Cancer researchers solve mystery of how Chd5 protein exerts its beneficial effects

A team of cancer researchers at Cold Spring Harbor Laboratory (CSHL) has solved the mystery of how one of the most powerful of the body's natural tumor-suppressing proteins, called Chd5, exerts its beneficial effects.

11 Jan 2013

Mutations signaling poor neuroblastoma prognosis identified

Children with neuroblastoma who have mutations in the ARID1A and ARID1B genes in their tumors have a poor prognosis compared with those without these alterations, show study findings.

4 Dec 2012

Children with changes in bully genes have poor survival

In a genome sequencing study of 74 neuroblastoma tumors in children, scientists at the Johns Hopkins Kimmel Cancer Center and the Children's Hospital of Philadelphia (CHOP) found that patients with changes in two genes, ARID1A and ARID1B, survive only a quarter as long as patients without the changes. The discovery could eventually lead to early identification of patients with aggressive neuroblastomas who may need additional treatments.

3 Dec 2012

UNSW-developed nanoparticle could improve effectiveness of chemotherapy for neuroblastoma

In a world-first, researchers from the Australian Centre for Nanomedicine at the University of New South Wales (UNSW) in Sydney have developed a nanoparticle that could improve the effectiveness of chemotherapy for neuroblastoma by a factor of five.

21 Nov 2012

New gene delivery vehicle opens route to the heart of cells in solid tumors

There are plenty of effective anticancer agents around. The problem is that, very often, they cannot gain access to all the cells in solid tumors. A new gene delivery vehicle may provide a way of making tracks to the heart of the target.

15 Nov 2012

Virginia G. Piper, TESARO announce initiation of TSR-011 clinical trial for advanced cancer

TESARO, Inc. announced today that the first clinical trial of its proprietary Anaplastic Lymphoma Kinase (ALK) inhibitor, TSR-011, has commenced with the dosing of the first patient at the Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare, a partnership between Scottsdale Healthcare and the Translational Genomics Research Institute (TGen).

2 Nov 2012

DNA method leads to more effective treatment of neuroblastoma in children

After leukaemia and brain tumours, neuroblastoma is the most common form of cancer to affect children. A thesis from the Sahlgrenska Academy, University of Gothenburg, Sweden, has studied a DNA method which is now used for all cases of neuroblastoma in Sweden, and which has led to more effective treatment at individual level.

15 Oct 2012

Whole-genome scan can help doctors choose best treatment option for children with neuroblastoma

A whole-genome scan to identify large-scale chromosomal damage can help doctors choose the best treatment option for children with neuroblastoma, one of the most common types of childhood cancer, finds an international collaboration jointly led by The Institute of Cancer Research, London.

15 Sep 2012

A mysterious form of cell death uncovers prime suspect for new cancer drug development

A mysterious form of cell death, coded in proteins and enzymes, led to a discovery by UNC researchers uncovering a prime suspect for new cancer drug development.

15 Sep 2012

Positive results from Santarus rifamycin SV MMX Phase III study on travelers' diarrhea

Santarus, Inc. today announced that its Phase III clinical study to evaluate the safety and efficacy of the investigational drug, rifamycin SV MMX, met the primary endpoint of reducing time to last unformed stool (TLUS) in patients with travelers' diarrhea.

12 Sep 2012

Neuroblastoma News and Research

Latest Neuroblastoma News and Research

Physician-researcher to lead pediatric Dream Team to create new treatments for childhood cancers

Scientists develop new cancer immunotherapy treatment for children with high-risk solid tumors

Three institutions partner to create research breakthroughs in children's health

CHOP expert to receive Pediatric Oncology Award from ASCO

Pediatric cancer charities collaborate to create new treatments for children with neuroblastoma

UHCC researchers identify role of RSK2 protein in cancer cell migration

Researchers determine that neuroblastoma is sensitive to BET bromodomain inhibitors

Glimmer of hope for imatinib-resistant GIST

Genome sequencing data gives important clues on cancer

Study refocuses on how neuroblastoma tumors evolve in response to medicine and other factors

Cancer researchers solve mystery of how Chd5 protein exerts its beneficial effects

Mutations signaling poor neuroblastoma prognosis identified

Children with changes in bully genes have poor survival

UNSW-developed nanoparticle could improve effectiveness of chemotherapy for neuroblastoma

New gene delivery vehicle opens route to the heart of cells in solid tumors

Virginia G. Piper, TESARO announce initiation of TSR-011 clinical trial for advanced cancer

DNA method leads to more effective treatment of neuroblastoma in children

Whole-genome scan can help doctors choose best treatment option for children with neuroblastoma

A mysterious form of cell death uncovers prime suspect for new cancer drug development

Positive results from Santarus rifamycin SV MMX Phase III study on travelers' diarrhea

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Neuroblastoma News and Research

Latest Neuroblastoma News and Research

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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