Neuroblastoma

Neuroblastoma is cancer that arises in immature nerve cells and affects mostly infants and children.

What is Neuroblastoma?

Neuroblastoma is a rare childhood cancer that develops from immature nerve cells called neuroblasts.

Latest Neuroblastoma News and Research

Phase 3 studies for rectal, brain, and kidney cancers to be presented by Dana-Farber researchers at ASCO 2023

Several phase 3 studies conducted by researchers from Dana-Farber Cancer Institute show promising results for patients with rectal, brain, and kidney cancers. The results of these studies, along with dozens of others led by Dana-Farber researchers, will be presented at the 2023 Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago.

26 May 2023

UQ neuroscientists uncover how vitamin D deficiency affects developing neurons in schizophrenia

Neuroscientists at The University of Queensland have uncovered how vitamin D deficiency affects developing neurons in schizophrenia, using new technology.

25 May 2023

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Researchers at Baylor College of Medicine/Texas Children's Cancer Center and collaborating institutions report interim results from a first-in-human phase 1 clinical trial evaluating the safety, antitumor activity and immunological characteristics of a genetically engineered natural killer T (NKT) cell immunotherapy for neuroblastoma, a childhood tumor that most commonly arises in the adrenal gland.

15 May 2023

Parkinson's linked to higher levels of pheomelanin in brain: Could it be a biomarker or treatment target?

Researchers discover that the substantia nigra of individuals with Parkinson’s disease had a higher concentration of pheomelanin.

6 Apr 2023

Clinical trial may change the paradigm of care for patients with ALK-driven high-risk neuroblastoma

In a significant step for the treatment of neuroblastoma, an international group of researchers led by Children's Hospital of Philadelphia (CHOP), Winship Cancer Institute of Emory University and the New Approaches to Neuroblastoma Therapy (NANT) Consortium has shown that the targeted therapy lorlatinib is safe and effective in treating high-risk neuroblastoma.

4 Apr 2023

New technique lights up cancerous tumors during surgery

A new technique that combines highly detailed, real-time images of inside the body with a type of infrared light has, for the first time, been used during surgery to differentiate between cancerous tumors and healthy tissue.

20 Mar 2023

First small molecules designed to stimulate immune cells against neuroblastoma

An MUSC Hollings Cancer Center research team has created what team members believe to be among the first small molecules designed to stimulate immune cells to fight cancer.

28 Feb 2023

NQO2 gene as a novel potential target in Parkinson’s disease

A new study under review at the journal Scientific Reports and currently available on the Research Square* preprint server aimed to analyze the toxic effects of 6OHDA along with a related role of NQO2 in murine and human astrocytes.

23 Feb 2023

A possible link between aggregation of SARS-CoV-2 proteins and protein misfolding diseases

A new study in the journal Nature Communications aimed to analyze the aggregation propensity in the proteins of both SARS-CoV-2 and SARS-CoV.

21 Feb 2023

What is the association between acute lymphoblastic leukemia and congenital cytomegalovirus infection?

Researchers evaluated the relationship between congenital cytomegalovirus (cCMV) infection and acute lymphoblastic leukemia (ALL).

11 Jan 2023

Study shows positive effect of concentrating surgery for children with neuroblastoma

Neuroblastoma is a tumor of the sympathetic nervous system that occurs mainly in young children. Every year, 25 children in the Netherlands receive this diagnosis. Surgery to remove the tumor tissue forms an important part of the treatment plan.

19 Dec 2022

Duke researchers find human DNA sequence divergence after split from common ancestor of chimpanzees

A team of Duke researchers has identified a group of human DNA sequences driving changes in brain development, digestion and immunity that seem to have evolved rapidly after our family line split from that of the chimpanzees, but before we split with the Neanderthals.

24 Nov 2022

Lund researchers identify the reason behind chemoresistance in neuroblastoma

Researchers at Lund University in Sweden have identified one of the reasons why the childhood cancer neuroblastoma becomes resistant to chemotherapy.

11 Nov 2022

Researchers propose origin-of-life molecule as therapeutic target for tailored cancer therapies

RNA, the molecule that gave rise to life, has been shown to be essential for repairing human genetic material and preventing mutations that might lead to developing cancer.

28 Oct 2022

Salk's three collaborative projects win 2022 Curebound Discovery Grant

The Salk Institute's American Cancer Society Professor Tony Hunter, Professor Reuben Shaw, and Assistant Professor Graham McVicker are among 12 inaugural 2022 Discovery Grant winners.

19 Oct 2022

Unc5-GPC3 complex modulates the migration of neurons and brain-derived cancer cells

During brain development, neurons have to migrate long distances through complex environments until they reach their final destination.

18 Oct 2022

New combination therapy shows potential to improve survival in children with neuroblastoma

Children who suffer a relapse of the aggressive cancer known as neuroblastoma have small chances of survival.

22 Aug 2022

New strategies to enhance the survival of children with neuroblastoma

Neuroblastoma, a childhood cancer that develops from neural cells on the adrenal glands, accounts for 15% of childhood cancer deaths. Almost half of children with high-risk neuroblastoma harbor extra copies of the gene MYCN (MYCN amplified), the primary driver of neuroblastoma and its resistance to therapy.

18 Aug 2022

Research identifies unique vulnerabilities in ALT cancers that can serve as novel therapeutic targets

In a study recently published in Cancer Research, a journal of the American Association for Cancer Research, a team of researchers led by C. Patrick Reynolds, M.D., Ph.D., director for the Texas Tech University Health Sciences Center School of Medicine Cancer Center, sought to expand upon his lab's previous research that showed ALT tumors identified by a biomarker known as C-circles share a common biology that confers vulnerabilities to be exploited for cancer therapy.

10 Aug 2022

CHOP helps launch new computational platform to harmonize pediatric cancer data

Children's Hospital of Philadelphia has helped launch a new computational platform that will harmonize pediatric cancer data, allowing researchers, pharmaceutical companies, and advocacy groups to accelerate the pace of drug development for pediatric cancer.

4 Aug 2022

Neuroblastoma

Overview

Neuroblastoma Classification

Neuroblastoma Diagnosis

Neuroblastoma Screening

Feature Articles

Neuroblastoma Treatment

Neuroblastoma Prognosis

Neuroblastoma History

Neuroblastoma Research

Neuroblastoma Symptoms

Latest Neuroblastoma News and Research

Phase 3 studies for rectal, brain, and kidney cancers to be presented by Dana-Farber researchers at ASCO 2023

UQ neuroscientists uncover how vitamin D deficiency affects developing neurons in schizophrenia

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Parkinson's linked to higher levels of pheomelanin in brain: Could it be a biomarker or treatment target?

Clinical trial may change the paradigm of care for patients with ALK-driven high-risk neuroblastoma

New technique lights up cancerous tumors during surgery

First small molecules designed to stimulate immune cells against neuroblastoma

NQO2 gene as a novel potential target in Parkinson’s disease

A possible link between aggregation of SARS-CoV-2 proteins and protein misfolding diseases

What is the association between acute lymphoblastic leukemia and congenital cytomegalovirus infection?

Study shows positive effect of concentrating surgery for children with neuroblastoma

Duke researchers find human DNA sequence divergence after split from common ancestor of chimpanzees

Lund researchers identify the reason behind chemoresistance in neuroblastoma

Researchers propose origin-of-life molecule as therapeutic target for tailored cancer therapies

Salk's three collaborative projects win 2022 Curebound Discovery Grant

Unc5-GPC3 complex modulates the migration of neurons and brain-derived cancer cells

New combination therapy shows potential to improve survival in children with neuroblastoma

New strategies to enhance the survival of children with neuroblastoma

Research identifies unique vulnerabilities in ALT cancers that can serve as novel therapeutic targets

CHOP helps launch new computational platform to harmonize pediatric cancer data

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

Neuroblastoma

Overview

Feature Articles

Neuroblastoma Treatment

Neuroblastoma Prognosis

Neuroblastoma History

Neuroblastoma Research

Neuroblastoma Symptoms

Latest Neuroblastoma News and Research

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

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