Osteoporosis News and Research

Latest Osteoporosis News and Research

Oral bisphosphonates linked to increased jaw necrosis

Researchers at the University Of Southern California, School Of Dentistry release results of clinical data that links oral bisphosphonates to increased jaw necrosis

1 Jan 2009

Quit smoking one week at a time

Even though millions of smokers will resolve to 'butt out' on January 1st, experts say many will be still be smoking on Valentine's Day. They have some tips to help quitters retain their resolve and strengthen their commitment to quitting which apply even to the likes of President-elect Barack Obama.

29 Dec 2008

Trial looks at high intensity focused ultrasound for locally recurrent prostate cancer

A Phase III clinical trial at New York University is investigating the safety and efficacy of High Intensity Focused Ultrasound (HIFU) for the treatment of locally recurrent prostate cancer following failed external beam radiation therapy (EBRT) using the Sonablate(R) 500.

22 Dec 2008

Discovery of gene mutation that appears to help prevent heart disease

Researchers at the University of Maryland School of Medicine in Baltimore have discovered a novel gene mutation among the Old Order Amish population that significantly reduces the level of triglycerides in the blood and appears to help prevent cardiovascular disease.

12 Dec 2008

Surge in older cancer survivors expected as baby boomers age

The United States could be faced with a national health care crisis in the coming decades as the country's baby boomer population ages and a growing number of older adults find themselves diagnosed with and living longer with cancer.

10 Dec 2008

Insufficient vitamin D causes weight gain and stunts growth in girls

Even in sun-drenched California, where scientists from the McGill University Health Centre (MUHC) and the University of Southern California conducted their study, vitamin D deficiency was found to cause higher body mass and shorter stature in girls at the peak of their growing spurt.

10 Dec 2008

Save money wih generics

Today, more than ever, consumers can opt for generic equivalents of brand-name medications at substantial cost savings.

10 Dec 2008

Better targeted, more cost-effective osteoporosis treatment could soon be a reality worldwide

A new method for determining more accurately at which point someone needs further diagnostic tests, or when immediate treatment is warranted, has been developed by The National Osteoporosis Guideline Group in the UK.

3 Dec 2008

Men who survive childhood leukemia have lower bone mineral density

Men who survived childhood leukemia treatment into adulthood were more likely to have low bone mineral density than other adults their age, putting them at risk of osteoporosis and bone fractures, according to a new study.

3 Dec 2008

Virtual colonoscopy has potential to screen for colorectal cancer and osteoporosis at same time

New research reveals that computed tomography (CT) colonography, also known as virtual colonoscopy, has the potential to screen for two diseases at once-colorectal cancer and osteoporosis, both of which commonly affect adults over age 50.

3 Dec 2008

Gut found to exert control over bone

When it comes to remodeling our bones-an ongoing process of break down and renewal that goes on throughout adulthood--researchers have new evidence that our guts play a surprisingly important role.

26 Nov 2008

MorphoSys and Galapagos enter alliance to co-develop novel therapeutic antibodies in bone and joint disease

MorphoSys AG and Galapagos NV announced today the launch of a long term co-development alliance aimed at discovering and developing antibody therapies based on novel modes of action in bone and joint disease, including rheumatoid arthritis, osteoporosis and osteoarthritis.

26 Nov 2008

Adiponectin is a metabolic link between obesity and bone mineral density

Researchers at the University of Toronto, Faculty of Medicine, Toronto, Canada, have discovered that adiponectin, a protein secreted from adipocytes, is a metabolic link that can explain, in part, the known positive relationship between obesity and both bone mineral density and reduced susceptibility to fractures.

25 Nov 2008

Non-pharmacologic interventions for the control of osteoporosis and obesity

The Department of Biomedical Engineering at Stony Brook University received a $1.8 million grant from the National Institutes of Health (NIH) to investigate the biologic and physical mechanisms of very low-magnitude mechanical signals and how they strengthen bone and muscle.

20 Nov 2008

Study identifies causes of bone loss in breast cancer survivors

Osteoporosis is a growing concern among breast cancer survivors and their doctors, because certain cancer drugs can cause bone loss.

19 Nov 2008

Computed tomography technology shows anorexia impairs adolescent bone development

Children and teenagers with even mild cases of anorexia exhibit abnormal bone structure, according to a new study appearing in the December issue of Radiology and presented at the annual meeting of the Radiological Society of North America (RSNA).

18 Nov 2008

Breakthrough reveals first ever complete structure of a nuclear hormone receptor on human DNA

For decades, scientists have been studying nuclear hormone receptors to gain a better understanding of how they turn genes on and off throughout the body and how they function as key drug targets for a number of diseases, such as diabetes, breast cancer, osteoporosis and high cholesterol. A new UVA Health System study, led by Fraydoon Rastinejad, Ph.D., professor of pharmacology and director of the UVA Center for Molecular Design and published in the October 29 issue of Nature, reveals the first ever complete structure of a nuclear hormone receptor on human DNA – a discovery that now clears a new path for scientists to design more effective drugs with fewer associated health risks. “Dr. Rastinejad’s findings fundamentally change the way people all over the world will study how nuclear hormone receptors work and introduces a new platform for designing better drugs,” says Jim Garrison, Ph.D., professor of pharmacology at UVA Health System. Nuclear hormone receptors, including the peroxisome proliferator-activated receptors (PPARs), are proteins that sit on the surface of cells and bind to specific hormones such as estrogen, progesterone and thyroid hormone. Once the receptor binds to its hormone and its DNA regulatory element, it can cause a number of alterations in the cell, switching genes on and off. These switches control the continual regulation of the metabolic system and reproductive tissues, as well as the development and differentiation of skin, bone and behavioral centers in the brain. “PPARs are widely studied because they regulate the genes that produce fat cells, glucose, insulin, lipids and metabolism,” says Dr. Rastinejad. “That’s what makes them such good drug targets for diseases like diabetes. We can design drugs more rationally to bind to the PPAR nuclear receptor complex to help regulate these functions in the body.” A number of diabetes drugs, called insulin sensitizers, have been developed based on that knowledge, but now that scientists have a clear view into how these receptors bind and what shape they take the door is wide open for the development of better drugs. "After 40 years of nuclear receptor research, we finally can view the first full and complete structure of a nuclear receptor, thanks to Dr. Rastinejad’s break-though achievement,” says Bert W. O’Malley, Ph.D., professor and chairman, Department of Molecular and Cellular Biology at Baylor College of Medicine who is widely considered a top expert in the field.

17 Nov 2008

Canadian women unaware of their vitamin D levels

A new survey, conducted by Ipsos Reid, reveals Canadian women are unaware of their vitamin D levels. According to the survey sponsored by Marc Sorenson, Ed.D, 97 per cent of the 516 Canadian women surveyed didn't know their vitamin D levels.

17 Nov 2008

Breast and prostate cancer treatment may result in bone loss

A new cross-Canada study has found that breast and prostate cancer treatment can foster bone loss.

16 Nov 2008

Osteoporosis drugs may prevent future bone growth

Patients who start and eventually stop regimens of a common class of osteoporosis drugs called bisphosphonates may be unable to benefit from parathyroid hormone (PTH), which can rebuild bone mass lost due to advanced stage osteoporosis. PTH has been proven to increase the volume and strength of the honeycomb-like bone infrastructure, the inner mesh that begins to diminish in old age.

13 Nov 2008

Osteoporosis News and Research

Latest Osteoporosis News and Research

Oral bisphosphonates linked to increased jaw necrosis

Quit smoking one week at a time

Trial looks at high intensity focused ultrasound for locally recurrent prostate cancer

Discovery of gene mutation that appears to help prevent heart disease

Surge in older cancer survivors expected as baby boomers age

Insufficient vitamin D causes weight gain and stunts growth in girls

Save money wih generics

Better targeted, more cost-effective osteoporosis treatment could soon be a reality worldwide

Men who survive childhood leukemia have lower bone mineral density

Virtual colonoscopy has potential to screen for colorectal cancer and osteoporosis at same time

Gut found to exert control over bone

MorphoSys and Galapagos enter alliance to co-develop novel therapeutic antibodies in bone and joint disease

Adiponectin is a metabolic link between obesity and bone mineral density

Non-pharmacologic interventions for the control of osteoporosis and obesity

Study identifies causes of bone loss in breast cancer survivors

Computed tomography technology shows anorexia impairs adolescent bone development

Breakthrough reveals first ever complete structure of a nuclear hormone receptor on human DNA

Canadian women unaware of their vitamin D levels

Breast and prostate cancer treatment may result in bone loss

Osteoporosis drugs may prevent future bone growth

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Osteoporosis News and Research

Latest Osteoporosis News and Research

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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