Osteoporosis

Osteoporosis is a progressive metabolic bone disease that causes a decrease in bone density and gives rise to weak, fragile bones that are prone to fracture. Most commonly, these fractures occur in the spine, wrist and hips when a person falls or bumps into something. If such an event triggers a visit to the doctor, a test of the bone mineral density called a DEXA scan may be performed and reveal osteoporosis.

The term osteoporosis refers to the porous (spongy) state of bone that eventually manifests as the bone’s ability to replenish itself declines over time. When individuals reach the age of around 40, the rate of bone breakdown starts to exceed the rate at which it is replaced, creating increasingly larger holes in the bone that make it less dense and more prone to fracture.

Some of the risk factors for osteoporosis such as gender, age and family history for the condition cannot be changed. However, factors such as diet and activity level can be improved to increase bone strength and individuals are advised to exercise regularly, eat a diet rich in vitamin D and calcium, and quit any smoking or drinking habits.

Osteoporosis is currently thought to be affecting more than 200 million people worldwide but is most common among older, post-menopausal women who have reduced levels of estrogen, an important contributor to bone health.
Bone Disease

Bone disease is a condition that damages the skeleton and makes bones weak and prone to fractures. Weak bones are not a natural part of aging. While strong bones begin in childhood, people of all ages can improve their bone health.

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Latest Osteoporosis News and Research

Study: Menopause symptoms are worse for women with premature ovarian insufficiency

Study: Menopause symptoms are worse for women with premature ovarian insufficiency

IOF and IFCC review describes the current status of assays for reference bone turnover markers

IOF and IFCC review describes the current status of assays for reference bone turnover markers

New taxonomic classification of non-skeletal rare congenital disorders with impact on bone physiology

New taxonomic classification of non-skeletal rare congenital disorders with impact on bone physiology

Inherited or transmitted gut microbes affect skeletal development in animals

Inherited or transmitted gut microbes affect skeletal development in animals

Incidence of osteoporotic hip fractures expected to escalate in some Eurasian countries

Incidence of osteoporotic hip fractures expected to escalate in some Eurasian countries

Researchers study the behavior of regulatory T cells to understand periodontal disease

Researchers study the behavior of regulatory T cells to understand periodontal disease

Researchers discover many genetic markers related to bone mineral accrual

Researchers discover many genetic markers related to bone mineral accrual

Novel drug may help treat osteoporosis, shows study

Novel drug may help treat osteoporosis, shows study

Researchers use massive sequencing methods to identify rare genetic bone disorder

Researchers use massive sequencing methods to identify rare genetic bone disorder

Researchers use precision medicine strategy to identify a new genetic skeletal disorder

Researchers use precision medicine strategy to identify a new genetic skeletal disorder

Osteoporosis drug also promotes infiltration of immune cells in breast tumors

Osteoporosis drug also promotes infiltration of immune cells in breast tumors

UC biophysicist develops useful instruments that can advance diagnosis, treatment of debilitating conditions

UC biophysicist develops useful instruments that can advance diagnosis, treatment of debilitating conditions

Study shows how minerals come together at molecular level to form bones, hard tissues

Study shows how minerals come together at molecular level to form bones, hard tissues

Obesity linked with risk of early hip fracture in postmenopausal women

Obesity linked with risk of early hip fracture in postmenopausal women

Researchers reveal link between gut bacteria and vitamin D levels

Researchers reveal link between gut bacteria and vitamin D levels

Health risks of prolonged sitting are reduced by exceeding weekly activity goals

Health risks of prolonged sitting are reduced by exceeding weekly activity goals

Researchers discover potential cellular target for eliminating bone breakdown in osteoporosis

Researchers discover potential cellular target for eliminating bone breakdown in osteoporosis

Experts publish Consensus Statement on management of osteoporosis in patients with CKD G4–G5D

Experts publish Consensus Statement on management of osteoporosis in patients with CKD G4–G5D

Osteoporosis drug increases bone mineral density in the hip and lumbar spine

Osteoporosis drug increases bone mineral density in the hip and lumbar spine

Older men are underdiagnosed and undertreated for osteoporosis

Older men are underdiagnosed and undertreated for osteoporosis