Commonly known as the "silent killer," ovarian cancer leads to approximately 15,000 deaths each year in the United States, according to the American Cancer Society. Approximately 20,000 new cases are diagnosed each year, with the majority in patients diagnosed with late stage disease where the cancer has spread beyond the ovary. The prognosis is poor in these patients, leading to the high mortality from this disease. A diagnostic test is needed that can provide adequate predictive value to stratify patients with a pelvic mass into high risk of invasive ovarian cancer versus those with low risk, as well as a screening test for the diagnosis of early-stage ovarian cancer, which is essential for improving overall survival in patients. Ovarian cancer has up to a 90% cure rate following surgery and/or chemotherapy if detected in stage 1.
What are the Ovaries?
The ovaries are a pair of organs in the female reproductive system that produce eggs and female hormones.
Implantable devices that release insulin into the body hold promise as an alternative way to treat diabetes without insulin injections or cannula insertions. However, one obstacle that has prevented their use so far is that the immune system attacks them after implantation, forming a thick layer of scar tissue that blocks insulin release.
JMIR Publications recently published "Understanding the Information Needs of Patients With Ovarian Cancer Regarding Genetic Testing to Inform Intervention Design: Interview Study" in JMIR Cancer, which reported that experts in gynecological cancer care recommend that all patients with invasive or high-grade ovarian cancer (OC) undergo genetic testing.
Frequent aspirin use is linked with lower ovarian cancer risk in individuals with multiple risk factors, according to a new study published in the Journal of Clinical Oncology.
Two research teams at the University of Tennessee Health Science Center (UTHSC) have been awarded the 2022 UTHSC Collaborative Research Network (CORNET)-Functional Genomics Award. Each team will receive $50,000 to support their novel projects.
Using nanoparticles to deliver cancer drugs offers a way to hit tumors with large doses of drugs while avoiding the harmful side effects that often come with chemotherapy.
A research group led by scientists at the University of São Paulo (USP) in São Carlos, Brazil, has identified a number of bioactive compounds in a marine sponge collected on Fernando de Noronha, an archipelago about 400 km off the coast of Brazil's Northeast region.
Jeni Rae Peters would make promises to herself as she lay awake nights after being diagnosed with breast cancer two years ago.
A study of 11,000 cancer patients reveals 42 hereditary genes which predispose individuals to a higher number of mutations that correlate with a greater probability of developing cancer.
In their recent publication in Cell Reports, a team of scientists, led by Xiling Shen, Ph.D., Chief Scientific Officer at the Terasaki Institute for Biomedical Innovation (TIBI), has demonstrated the pivotal role of an enzyme, glucose-6-phosphate dehydrogenase (G6PD), in facilitating ovarian cancer (OC) growth and metastasis in the omentum, a curtain of fatty tissue found in the abdominal cavity.
The American Academy of Pediatrics recommends that mothers to continue breastfeeding for two years or beyond.
Due to the development of resistance to chemotherapy and recurring tumors, patients with ovarian cancer often have low survival rates.
Medicines used to prevent bone loss may help lower the risk of ovarian cancer according to research by The University of Queensland.
Researchers from the University of Sheffield and Stanford University in the US have discovered there are specific genetic signals in people who develop severe coronavirus infection.
A new clinical trial studying the effectiveness of a combination of immunotherapy treatments could be more effective for patients with ovarian cancer who are resistant to traditional interventions.
Inherited mutations in the BRCA1 gene can significantly increase a person's risk of breast and ovarian cancer-;but not every mutation in the gene is harmful.
A compound, developed by a team including scientists from The University of Texas Health Science Center at San Antonio, kills a range of hard-to-treat cancer types in petri dishes and animal models by targeting a previously unexploited vulnerability, a new study reports.
Ovarian cancer has one of the highest death rates of all cancers. One reason for this is that cancer turns the body's defenses against itself. However, new research from Nagoya University published in Matrix Biology suggests that vitamin D can effectively prevent one of the key pathways used by this cancer.
The accelerated advancement of cancer immunology and immunotherapy, a type of biological therapy that boosts the immune system's ability to recognize and kill cancer cells, has significantly improved the effectiveness of cancer treatment and patient outcomes.
A research team at the School of Biological Sciences, the University of Hong Kong, has revealed novel cellular and molecular interactions between cancer cells and tumor-associated macrophages that promote peritoneal metastasis of ovarian cancer.
Investing in and improving research, awareness and equity in women's heart health are critical for the health and well-being of women, according to a new Presidential Advisory from the American Heart Association, published today in the Association's flagship journal Circulation.