Ovarian Cancer

Commonly known as the "silent killer," ovarian cancer leads to approximately 15,000 deaths each year in the United States, according to the American Cancer Society. Approximately 20,000 new cases are diagnosed each year, with the majority in patients diagnosed with late stage disease where the cancer has spread beyond the ovary. The prognosis is poor in these patients, leading to the high mortality from this disease. A diagnostic test is needed that can provide adequate predictive value to stratify patients with a pelvic mass into high risk of invasive ovarian cancer versus those with low risk, as well as a screening test for the diagnosis of early-stage ovarian cancer, which is essential for improving overall survival in patients. Ovarian cancer has up to a 90% cure rate following surgery and/or chemotherapy if detected in stage 1.
The Ovaries

The ovaries are a pair of organs in the female reproductive system. They are located in the pelvis, one on each side of the uterus. The uterus is the hollow, pear-shaped organ where a baby grows. Each ovary is about the size and shape of an almond. The ovaries produce eggs and female hormones. Hormones are chemicals that control the way certain cells or organs function.

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Latest Ovarian Cancer News and Research

NCI gives 'exceptional' rating to Penn's Abramson Cancer Center

NCI gives 'exceptional' rating to Penn's Abramson Cancer Center

Chlamydiae need a lot of glutamine to multiply in human cells

Chlamydiae need a lot of glutamine to multiply in human cells

Avoiding care during the pandemic could mean life or death

Avoiding care during the pandemic could mean life or death

Exploiting 'synthetic lethality' to identify cancer targets

Exploiting 'synthetic lethality' to identify cancer targets

Population screening has potential to identify individuals at risk for inherited genetic conditions

Population screening has potential to identify individuals at risk for inherited genetic conditions

Study: L-Grb2 has therapeutic efficacy in preclinical models of ovarian and uterine cancer

Study: L-Grb2 has therapeutic efficacy in preclinical models of ovarian and uterine cancer

Novel drug could enable the immune system to attack ovarian cancer

Novel drug could enable the immune system to attack ovarian cancer

Blocking tumor-promoting protein could bolster immunotherapy's effectiveness, study suggests

Blocking tumor-promoting protein could bolster immunotherapy's effectiveness, study suggests

New test could guide and improve treatment options for women with deadly ovarian cancer

New test could guide and improve treatment options for women with deadly ovarian cancer

Accelerating the Diagnosis and Treatment of Cancer with Mass-Spectrometry Based Techniques

Accelerating the Diagnosis and Treatment of Cancer with Mass-Spectrometry Based Techniques

Study finds link between high levels of dietary AGEs and breast cancer risk

Study finds link between high levels of dietary AGEs and breast cancer risk

Study investigates potential of adoptive cell therapy in combination with checkpoint inhibitors

Study investigates potential of adoptive cell therapy in combination with checkpoint inhibitors

Key recommendations on genetic testing of men for prostate cancer

Key recommendations on genetic testing of men for prostate cancer

Better testing could lead to improved treatments for a specific type of ovarian cancer

Better testing could lead to improved treatments for a specific type of ovarian cancer

Study could make genetic testing more accessible to women

Study could make genetic testing more accessible to women

Study compares cediranib plus olaparib and standard of care therapy for platinum-sensitive ovarian cancer

Study compares cediranib plus olaparib and standard of care therapy for platinum-sensitive ovarian cancer

Adoptive T-cell therapy targeting MAGE-A4 achieves responses in patients with multiple solid tumors

Adoptive T-cell therapy targeting MAGE-A4 achieves responses in patients with multiple solid tumors

Targeted therapy pralsetinib shows high response rates in patients with RET fusion-positive cancers

Targeted therapy pralsetinib shows high response rates in patients with RET fusion-positive cancers

New test may help detect prostate cancer earlier and with greater accuracy

New test may help detect prostate cancer earlier and with greater accuracy

Researchers investigate the early development of ovarian cancer

Researchers investigate the early development of ovarian cancer