Ovarian Cancer

Commonly known as the "silent killer," ovarian cancer leads to approximately 15,000 deaths each year in the United States, according to the American Cancer Society. Approximately 20,000 new cases are diagnosed each year, with the majority in patients diagnosed with late stage disease where the cancer has spread beyond the ovary. The prognosis is poor in these patients, leading to the high mortality from this disease. A diagnostic test is needed that can provide adequate predictive value to stratify patients with a pelvic mass into high risk of invasive ovarian cancer versus those with low risk, as well as a screening test for the diagnosis of early-stage ovarian cancer, which is essential for improving overall survival in patients. Ovarian cancer has up to a 90% cure rate following surgery and/or chemotherapy if detected in stage 1.

What are the Ovaries?

The ovaries are a pair of organs in the female reproductive system that produce eggs and female hormones.

Oophorectomy for Ovarian Cancer

Who Gets Ovarian Cancer?

Ovarian Cancer Symptoms

Ovarian Cancer Treatment

Ovarian Cancer Diagnosis, Prevention

Ovarian Cancer and Genetics

Ovarian Cancer

Latest Ovarian Cancer News and Research

Study reveals CAR T approach for hard-to-treat solid tumors

Chimeric antigen receptor T-cell therapy - CAR T for short - has been a major advance in treating blood cancers like leukemia and lymphoma.

30 Mar 2026

Study links diagnostic timing to ovarian cancer survival outcomes

The study "Diagnostic Timing and Ovarian Cancer Survival in North Carolina" has been published in the latest issue of JAMA Network Open. Led by a team of UNC-Chapel Hill researchers, this study explored the relationship between survival and how quickly patients are diagnosed with ovarian cancer.

27 Mar 2026

Blood pressure drug boosts effectiveness of cancer therapy

In a new Dartmouth Cancer Center (DCC) study led by clinical researcher Tyler J. Curiel, MD, MPH, FACP, investigators found that the FDA-approved blood pressure drug telmisartan can significantly enhance the cancer-killing activity of the targeted therapy olaparib, potentially expanding its use to many more patients.

25 Mar 2026

Systematic review identifies stress-induced biological triggers in oncology

Stress is a constant companion in the oncologist's office. It appears at the time of diagnosis, increases with each stage of treatment, and often does not resolve even after therapy formally ends. It accompanies therapeutic decisions, waiting for test results, fear of recurrence, and changes in daily functioning. Studies show that chronic stress can trigger biological processes that promote disease progression and weaken the body's defenses.

25 Mar 2026

New approach helps immune cells find and attack solid tumors

A technique that transforms immune cells into cancer-seeking bloodhounds may overcome a roadblock that has hampered immunotherapy for solid tumors, according to a new study by Stanford Medicine researchers.

24 Mar 2026

Why are men missing cancer tests despite higher positive rates?

A study highlights a gap in cancer prevention, showing men undergo genetic testing less often yet are more likely to carry high-risk cancer variants.

18 Mar 2026

Lysosomal storage of drugs may influence cancer treatment outcomes

One of oncology's biggest challenges is that the same treatment can work well for some patients but fail completely in others.

17 Mar 2026

Fertility treatments linked to small increases in some cancers

Findings indicate small increases in certain cancers linked to assisted reproduction, though overall cancer incidence aligns with the general female population.

13 Mar 2026

New strategy boosts immunotherapy against aggressive ovarian cancer

Cells in our immune system are best known for providing security against external invaders such as bacteria and viruses. These immune cells also guard against internal threats, including cancerous tumors.

5 Mar 2026

Armored CAR T cells overcome tumor defenses in solid cancers

UCLA scientists have developed a next-generation CAR-T cell therapy that can overcome the immunosuppressive tumor microenvironment, a protective shield that tumors use to weaken immune cells, block their attack and fuel tumor growth.

4 Mar 2026

Detecting the "scent" of ovarian cancer with AI

Using machine learning, an electronic nose can "smell" early signs of ovarian cancer in the blood. The method is precise and, according to the LiU researchers behind the study, it could eventually be used to find many different cancers. The study is published in the scientific journal Advanced intelligent systems.

23 Feb 2026

Hormone replacement therapy shows no rise in overall mortality

Menopausal hormone therapy (commonly known as hormone replacement therapy or HRT) is not associated with an increased risk of death, finds a Danish study of over 800,000 women published by The BMJ today.

18 Feb 2026

OVACell project pioneers viral target immunotherapy for ovarian cancer

A small team at OVACell is fighting ovarian cancer with hidden viral sequences and advanced immunotherapies.

16 Feb 2026

New strategy may improve ovarian cancer treatment outcomes

A new study published by Mayo Clinic researchers suggests that ovarian cancer cells quickly activate a survival response after PARP inhibitor treatment, and blocking this early response may make this class of drugs work better.

12 Feb 2026

MHC class II marks stronger immune response and longer survival in ovarian cancer

A new study sheds light on why some patients with the most aggressive form of ovarian cancer respond better to treatment than others.

10 Feb 2026

Mesothelial cells enable rapid invasion and spread of ovarian cancer

Ovarian cancer kills more women than any other gynecological cancer. Most patients receive their diagnosis only after the disease spreads throughout the abdomen.

7 Feb 2026

New prevention strategy can reduce deadly ovarian cancer risk by nearly 80%

A prevention strategy developed by Canadian researchers can reduce the risk of the most common and deadly form of ovarian cancer by nearly 80 per cent, according to a new study published today in JAMA Network Open by researchers at the University of British Columbia (UBC).

2 Feb 2026

Lifetime heavy drinking sharply raises colorectal cancer risk, major US study finds

Lifetime alcohol intake, not just recent drinking, is associated with colorectal cancer risk in older adults followed in the PLCO Cancer Screening Trial. Heavy and consistent long-term drinking was linked to higher colorectal cancer risk, while alcohol cessation was associated with lower odds of early, nonadvanced adenomas.

28 Jan 2026

Lifetime alcohol consumption associated with higher risk of colorectal cancer

Studies have demonstrated a link between alcohol consumption and an elevated risk of colorectal cancer. New research now reveals that higher lifetime alcohol consumption is also associated with a higher risk,

26 Jan 2026

Trojan horse immunotherapy opens tumors to immune system attack

Scientists at the Icahn School of Medicine at Mount Sinai have developed an experimental immunotherapy that takes an unconventional approach to metastatic cancer: instead of going after cancer cells directly, it targets the cells that protect them.

22 Jan 2026