Ovarian Cancer

Commonly known as the "silent killer," ovarian cancer leads to approximately 15,000 deaths each year in the United States, according to the American Cancer Society. Approximately 20,000 new cases are diagnosed each year, with the majority in patients diagnosed with late stage disease where the cancer has spread beyond the ovary. The prognosis is poor in these patients, leading to the high mortality from this disease. A diagnostic test is needed that can provide adequate predictive value to stratify patients with a pelvic mass into high risk of invasive ovarian cancer versus those with low risk, as well as a screening test for the diagnosis of early-stage ovarian cancer, which is essential for improving overall survival in patients. Ovarian cancer has up to a 90% cure rate following surgery and/or chemotherapy if detected in stage 1.
The Ovaries

The ovaries are a pair of organs in the female reproductive system. They are located in the pelvis, one on each side of the uterus. The uterus is the hollow, pear-shaped organ where a baby grows. Each ovary is about the size and shape of an almond. The ovaries produce eggs and female hormones. Hormones are chemicals that control the way certain cells or organs function.

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Overview

Feature Articles

Latest Ovarian Cancer News and Research

New molecular mechanism that regulates the sentinel cells of the immune system

New molecular mechanism that regulates the sentinel cells of the immune system

New approach shows promise as a treatment for chemo-resistant ovarian cancer

New approach shows promise as a treatment for chemo-resistant ovarian cancer

Experimental heart disease drug may treat chemo-resistant ovarian cancer

Experimental heart disease drug may treat chemo-resistant ovarian cancer

New type of immunotherapy shows promise for future treatment of ovarian cancer

New type of immunotherapy shows promise for future treatment of ovarian cancer

Study helps predict which ovarian cancer patients will not benefit from immune-PARP combo

Study helps predict which ovarian cancer patients will not benefit from immune-PARP combo

Study paves way for identifying ovarian cancer patients who will not benefit from combination therapy

Study paves way for identifying ovarian cancer patients who will not benefit from combination therapy

Trial of cancer drug OxaliTex promises lower toxicity and more robust action

Trial of cancer drug OxaliTex promises lower toxicity and more robust action

Family history elevates heart disease mortality risk in women who had premature removal of ovaries

Family history elevates heart disease mortality risk in women who had premature removal of ovaries

Inhibiting specific protein could make radiation therapy for colon cancer more effective

Inhibiting specific protein could make radiation therapy for colon cancer more effective

Targeted therapy may increase overall survival in patients with pancreatic cancer

Targeted therapy may increase overall survival in patients with pancreatic cancer

New methods to decipher how natural substances affect the body’s hormone balance

New methods to decipher how natural substances affect the body’s hormone balance

Scientists discover novel molecular pathway involved in immunotherapy response

Scientists discover novel molecular pathway involved in immunotherapy response

Statins could reduce ovarian cancer risk, study suggests

Statins could reduce ovarian cancer risk, study suggests

Simple blood test measures the body's immune response to improve ovarian cancer diagnosis

Simple blood test measures the body's immune response to improve ovarian cancer diagnosis

Study provides a detailed molecular snapshot of endometrial cancer

Study provides a detailed molecular snapshot of endometrial cancer

Autophagy genes work against tumors in some ovarian cancers

Autophagy genes work against tumors in some ovarian cancers

Purdue-developed 'fluorescent markers' begin Phase 3 clinical trials

Purdue-developed 'fluorescent markers' begin Phase 3 clinical trials

UMass Amherst study aims to develop new test for BRCA-positive lactating moms

UMass Amherst study aims to develop new test for BRCA-positive lactating moms

Developing tests for genetic signs could lead to earlier cancer detection

Developing tests for genetic signs could lead to earlier cancer detection

Women’s Heart Fund announces launch of ‘Community Conversations with the CDI’

Women’s Heart Fund announces launch of ‘Community Conversations with the CDI’