Ovarian Cancer News and Research

Latest Ovarian Cancer News and Research

Adverse early life experiences and abuse may lead women to unnecessary, harmful surgeries

Mayo Clinic researchers report that women who suffered adverse childhood experiences or abuse as an adult are 62 percent more likely to have their ovaries removed before age 46.

7 Jun 2017

Positive results for AstraZeneca’s PARP inhibitor Lynparza in advanced breast cancer

A new study has shown that AstraZeneca's Lynparza (olaparib) can significantly slow the progress of breast cancer that is caused partially due to mutations of the culprit gene called BRCA. BRCA gene mutations are responsible for around 3% of all breast cancers. These cases of the disease that have a basis in the gene are notoriously difficult to treat and women who are tested positive for this gene may even opt for removal of their breasts before even the cancer strikes. Noted actress Angelina Jolie went for a similar prophylactic mastectomy.

5 Jun 2017

Senators’ dueling web shoutouts echo nation’s partisan divide on Obamacare

Politically, Sens. Rob Portman (R-Ohio) and Mark Warner (D-Va.) are not all that far apart. Both are moderates who rejected proposed cuts in Medicaid funds. And yet, in the highly polarized atmosphere of Washington, D.C., they find themselves rallying constituents along diametrically opposed positions.

1 Jun 2017

Open-access BRCA testing for inherited breast cancer enables identification of missed carriers

Ashkenazi Jewish women are known to have a predisposition to the inherited breast cancers BRCA1 and BRCA2, but currently genetic testing in this group is limited to women affected by breast and ovarian cancers and those who are unaffected but have a family history of the disease.

27 May 2017

Combined use of two existing drugs appears to slow cancer's tendency to spread, study shows

A team led by Johns Hopkins researchers has discovered a biochemical signaling process that causes densely packed cancer cells to break away from a tumor and spread the disease elsewhere in the body.

26 May 2017

New study offers insight into how to improve chemotherapy strategies for ovarian cancer

Most women diagnosed with ovarian cancer undergo surgery to remove as many of the tumors as possible. However, it is usually impossible to eliminate all of the cancer cells because they have spread throughout the abdomen. Surgery is therefore followed by 18 weeks of chemotherapy.

24 May 2017

Researchers identify DNA repair deficiency in many types of solid tumors

A new investigation of more than 48,000 stored tumor samples finds evidence of a key deficiency in a repair mechanism designed to keep DNA from being mutated and causing cancer.

18 May 2017

Prototype drug prevents lung cancer tumors in mice by using novel mechanism

Lung cancer tumors were prevented in mice by a novel small molecule that directly activates a tumor suppressor protein.

16 May 2017

Mayo Clinic research advances understanding of DNA repair mechanisms

We humans like to think our DNA is well-protected in the nucleus of each cell. But it's a hard life for the hard-working genetic code.

12 May 2017

Scientists identify unusual mutations in endometriosis using gene sequencing tools

Using gene sequencing tools, scientists from Johns Hopkins Medicine and the University of British Columbia have found a set of genetic mutations in samples from 24 women with benign endometriosis, a painful disorder marked by the growth of uterine tissue outside of the womb.

11 May 2017

Study finds worse survival rates for heart failure despite advances in treatment

A new analysis finds that, despite advances in care, men and women with a diagnosis of heart failure continue to have worse survival rates than patients with certain common cancers.

4 May 2017

Myriad and Clovis ink deal on FDA-approved BRACAnalysis CDx test to identify patients with germline BRCA mutations for rucaparib treatment

Myriad Genetics, Inc. and Clovis Oncology, Inc. have announced a companion diagnostic collaboration to support a post-marketing regulatory commitment related to Clovis’ PARP inhibitor, Rubraca. Financial terms of the deal were not disclosed.

3 May 2017

NUS researchers develop novel dual-mode contrast agent for better liver cancer imaging

Scientists from the National University of Singapore have developed a novel nanodiamond-based contrast agent - a chemical "dye" used to enhance the visibility of internal body structures in magnetic resonance imaging - that improves visualization of liver cancer tumors

2 May 2017

Combination therapy may be effective option for treating some women with ovarian cancer

Researchers have been trying to understand why up to 85 percent of women experience recurrence of high-grade serous ovarian cancer -- the most common subtype of ovarian cancer -- after standard treatment with the chemotherapy drug carboplatin.

2 May 2017

Study identifies expression of tumor antigen as marker for aggressive ovarian cancer

Patients who expressed the tumor antigen NY-ESO-1 had more aggressive cancers and were more likely to die early from their disease, according to a large study conducted by Roswell Park Cancer Institute researchers and published online ahead of print in the journal Gynecologic Oncology.

26 Apr 2017

Second cancers are far deadlier in younger people than older adults

Second cancers in children and adolescents and young adults are far deadlier than they are in older adults and may partially account for the relatively poor outcomes of cancer patients ages 15-39 overall, a new study by UC Davis researchers has found.

20 Apr 2017

Ovarian Cancer News and Research

Latest Ovarian Cancer News and Research

Adverse early life experiences and abuse may lead women to unnecessary, harmful surgeries

Positive results for AstraZeneca’s PARP inhibitor Lynparza in advanced breast cancer

Senators’ dueling web shoutouts echo nation’s partisan divide on Obamacare

Open-access BRCA testing for inherited breast cancer enables identification of missed carriers

Combined use of two existing drugs appears to slow cancer's tendency to spread, study shows

New study offers insight into how to improve chemotherapy strategies for ovarian cancer

Researchers identify DNA repair deficiency in many types of solid tumors

Prototype drug prevents lung cancer tumors in mice by using novel mechanism

Mayo Clinic research advances understanding of DNA repair mechanisms

Scientists identify unusual mutations in endometriosis using gene sequencing tools

Study finds worse survival rates for heart failure despite advances in treatment

Myriad and Clovis ink deal on FDA-approved BRACAnalysis CDx test to identify patients with germline BRCA mutations for rucaparib treatment

NUS researchers develop novel dual-mode contrast agent for better liver cancer imaging

Combination therapy may be effective option for treating some women with ovarian cancer

Study identifies expression of tumor antigen as marker for aggressive ovarian cancer

Second cancers are far deadlier in younger people than older adults

Researcher aims to eliminate chemotherapy-resistant ovarian tumors using virus treatment

NCCN Radiation Therapy Compendium adds nine new clinical practice guidelines in oncology

Hypertension linked to better outcomes for subset of ovarian cancer patients

Research finds diagnostic tests to be less accurate for children with impaired kidney function

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

Ovarian Cancer News and Research

Latest Ovarian Cancer News and Research

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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