Pharmacology News and Research

Latest Pharmacology News and Research

New combination therapy holds promise for treating HER2-positive breast cancer

Resistance to therapy is a major problem in the cancer field. Even when a treatment initially works, the tumors often find ways around the therapy.

10 Apr 2015

Stem cell disease model reveals how tumor suppressor may drive bone cancer

Using induced pluripotent stem cells (iPSCs), a team led by Mount Sinai researchers has gained new insight into genetic changes that may turn a well known anti-cancer signaling gene into a driver of risk for bone cancers, where the survival rate has not improved in 40 years despite treatment advances.

10 Apr 2015

Researchers use new gene editing tool to cut HIV DNA

The virus that causes AIDS is an efficient and crafty retrovirus. Once HIV inserts its DNA into the genome of its host cells, it has a long incubation period, and can remain dormant and hidden for years.

10 Apr 2015

Simple dietary intervention can help reduce weight gain

A University of Calgary study has found that rats fed a fibre supplement while on a high fat and high sugar diet show a much lower weight gain than those who did not eat the fibre. A team of researchers from the university's Cumming School of Medicine and the Faculty of Kinesiology says the study helps scientists better understand the mechanisms of weight control and energy balance.

9 Apr 2015

PAREXEL announces three new academic programs to develop global biopharmaceutical workforce

PAREXEL International Corporation, a leading global biopharmaceutical services provider, today announced three new academic programs at the PAREXEL Academy.

From Parexel 8 Apr 2015

Combination of signaling molecules can inhibit growth of breast cancer cells

Researchers at UT Southwestern Medical Center have uncovered how the body's inflammatory response can alter how estrogen promotes the growth of breast cancer cells.

6 Apr 2015

New biodegradable membrane reduces wound healing time by 50%

Treatments to regenerate skin from burns become tedious and long lasting; however, Mexican researchers developed a biodegradable membrane that allows to transfer skin cells (keratinocytes) to burn wounds, when placed on the wound. The method reduces healing time by 50 percent.

3 Apr 2015

AMRI plans to close its API manufacturing facility in Holywell, U.K.

AMRI announced today that it has decided to close its Holywell, U.K. facility following a consultation process with employee representatives.

3 Apr 2015

Study: APOSEC protein concentrate reduces severity of damage after spinal cord injuries

In tests conducted on animals, the APOSEC protein concentrate extracted from white blood cells has reduced the severity of damage after an accident involving spinal cord injuries when the agent was injected in the abdominal cavity 40 minutes after the acute lesion. As a result, severe consequential paralyses can be prevented.

2 Apr 2015

VSV-based vaccine yields promising results for rapid development of effective Ebola vaccine

A live vaccine based on the "Vesicular Stomatitis Virus" (VSV) has yielded highly promising results for the rapid development of an effective vaccine against the Ebola virus. This vaccine would only need to be injected once for long-lasting immunoprotection.

2 Apr 2015

Penn Med's BLINKER Team named one of 16 finalists in NIH 'Follow that Cell Challenge'

James Eberwine, PhD, the Elmer Holmes Bobst Professor of Systems Pharmacology and Experimental Therapeutics, at the Perelman School of Medicine at the University of Pennsylvania, was named one of 16 finalists in the first phase of the Follow that Cell Challenge funded by the National Institutes of Health. The competition was run by crowdsourcing company Innocentive and 687 designated "solvers" entered initially.

2 Apr 2015

Purdue researchers identify new class of chemical insecticides to control mosquitoes

Purdue researchers have identified a new class of chemical insecticides that could provide a safer, more selective means of controlling mosquitoes that transmit key infectious diseases such as dengue, yellow fever and elephantiasis.

2 Apr 2015

Selvita commences IND-enabling studies for its first oncology drug candidate

Selvita, the largest drug discovery company in Central and Eastern Europe, announced today that it is commencing IND-enabling studies for SEL24 project, the company’s first oncology drug candidate.

1 Apr 2015

Study suggests possible role for caffeine in AD treatment

The proposed link between caffeine and reductions in the beta amyloid plaque accumulation characteristic of Alzheimer's disease (AD) suggest a possible role for caffeine in AD treatment. The latest evidence linking beta amyloid protein to Alzheimer's disease and exploring the relationship between caffeine and beta amyloid are featured in a review article in Journal of Caffeine Research: The International Multidisciplinary Journal of Caffeine Science, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

31 Mar 2015

PAREXEL introduces new version of Regulatory Information Management platform

PAREXEL International Corporation, a leading global biopharmaceutical services provider, today introduced the latest version of its Regulatory Information Management (RIM) platform: LIQUENT InSight 6.0.

From Parexel 31 Mar 2015

Researchers create 3D skin maps to detect molecular, microbial variations across the body

Researchers at the University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences used information collected from hundreds of skin swabs to produce three-dimensional maps of molecular and microbial variations across the body.

31 Mar 2015

Effective therapy enables immune system recovery in majority of children

Most children with HIV who have low levels of a key immune cell eventually recover levels of this cell after they begin treatment, according to a new study conducted by researchers at UCLA and other institutions in the U.S. and Brazil.

30 Mar 2015

Genes crucial for vision multiplied in early stages of vertebrate evolution

A new study from SciLifeLab at Uppsala University published in PLOS ONE shows that genes crucial for vision were multiplied in the early stages of vertebrate evolution and acquired distinct functions leading to the sophisticated mechanisms of vertebrate eyes.

30 Mar 2015

Transition announces positive results from ELND005 AME and renal clearance studies

Transition Therapeutics Inc. today announced results from two phase 1 clinical studies of neuropsychiatric drug candidate ELND005. These studies, an absorption-metabolism-excretion ("AME") study and a renal clearance study, are specialized clinical pharmacology trials that are required by the United States Food and Drug Administration for the approval of most drugs in development.

26 Mar 2015

USF scientists identify potential compounds to improve cardiovascular system, small vessel disease

University of South Florida scientists have identified a group of compounds with the potential for beneficial effects on the cardiovascular system and small vessel disease while researching grape seed extracts discovered at USF.

26 Mar 2015