Pharmacology

Pharmacology is the study of how chemical substances interact with living systems. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties, interactions, toxicology, therapy, and medical applications and antipathogenic capabilities.

Pharmacology

Pharmacology is the study of the action of drugs on a biologic system. It incorporates components of medicine and biology, and how they interact with each other.

What is in Silico?

What is Drug Absorption?

Drug Distribution

Drug Excretion / Elimination

Drug Metabolism

Pharmacokinetics

What is Psychopharmacology?

Psychopharmacology and Neuropsychopharmacology Research

What is Pharmacoepidemiology?

What is Neuropharmacology?

Metabolomics in Pharmacology

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Importance of Allostery in Pharmacology

Importance of Pharmacology in Dentistry

Pharmacist Career

What is Quantitative Systems Pharmacology (QSP) Modeling?

Latest Pharmacology News and Research

Living human breast milk cells offer insight into breast cancer development

Researchers have explored the cellular changes that occur in human mammary tissue in lactating and non-lactating women, offering insight into the relationship between pregnancy, lactation, and breast cancer.

28 Jan 2022

Desipramine and L-cycloserine together reduce ceramide levels in the retina and enhance vision

Researchers from the University of California, Irvine have discovered that the absence of Adiponectin receptor 1 protein (AdipoR1), one of the principal enzymes regulating ceramide homeostasis in the retina, leads to an accumulation of ceramides in the retina, resulting in progressive photoreceptor cell death and ultimately vision loss.

28 Jan 2022

Unhealthy vaginal microbiome in mothers may contribute to infant deaths and altered development

A new study in mice from University of Maryland School of Medicine researchers showed that an unhealthy vaginal microbiome in pregnant mothers in combination with an unhealthy diet contributed to increased pup deaths and altered development in the surviving babies.

27 Jan 2022

UofL professor wins $6.7 million grant to investigate how metals cause lung cancer

For nearly three decades, John Pierce Wise Sr. has investigated the connection between exposure to metals and cancer, working both in the lab and in the field, reporting significant discoveries about the effects of metals on chromosomes in lung cancer and how those effects differ in humans and in whales.

27 Jan 2022

The doctor didn’t show up, but the hospital ER still charged $1,012

Dhaval Bhatt had been warned about hospital emergency rooms. "People always told me to avoid the ER in America unless you are really dying," said Bhatt, an immigrant from India who got a Ph.D. in pharmacology in the U.S. and is now a research scientist at Washington University in St. Louis.

24 Jan 2022

Nano-bubbles containing ACE2 protein can block infection from broad strains of SARS-CoV-2

Scientists at Northwestern Medicine and The University of Texas MD Anderson Cancer Center have identified natural nano-bubbles containing the ACE2 protein (evACE2) in the blood of COVID-19 patients and discovered these nano-sized particles can block infection from broad strains of SARS-CoV-2 virus in preclinical studies.

21 Jan 2022

New study to help understand the effect of cancer medicine

When the muscles become acidic after doing too many press-ups, squats or cycling to work, it is because of lactic acid.

21 Jan 2022

Natural extracellular vesicles containing ACE2 protein could fight new SARS-CoV-2 variants

Scientists at The University of Texas MD Anderson Cancer Center and Northwestern Medicine have identified natural extracellular vesicles containing the ACE2 protein (evACE2) in the blood of COVID-19 patients that can block infection from broad strains of SARS-CoV-2 virus in preclinical studies. The study was published today in Nature Communications.

20 Jan 2022

‘Decoy’ protein mitigates lung damage, death induced by aggressive SARS-CoV-2 variants

A drug treatment that acts as a decoy against SARS-CoV-2 was highly effective at preventing death and lung damage in humanized animal models of severe COVID-19 disease, according to a Nature Chemical Biology study from researchers at the University of Illinois Chicago.

19 Jan 2022

COPD: Ion channels in immune cells could potentially be targets for new therapies

Chronic obstructive pulmonary disease – COPD for short – is one of the most common diseases of the lung. It affects almost 300 million people worldwide, of which about three million die every year.

17 Jan 2022

Genome editing in vascular endothelial cells made possible with a powerful new delivery system

Northwestern Medicine scientists developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to endothelial cells, which line blood vessel walls.

16 Jan 2022

UC researchers to examine how stress hormones affect cell degeneration in Parkinson's patients

Stress can have a negative effect on anyone's health but presents particular challenges for people with Parkinson's disease.

13 Jan 2022

Cannabinoids may prevent infection with SARS-CoV-2, including variants

A new study published in the Journal of Natural Products of the American Chemical Society and American Society of Pharmacognosy has shown that isolated cannabinoids or those in hemp extracts have the potential to prevent and treat the infection with the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) – primarily by blocking viral cell entry.

13 Jan 2022

UCLA study provides new insights into molecular 'crosstalk' in pancreas cancer cells

Research led by scientists at the Jonsson Comprehensive Cancer Center (JCCC) at UCLA provides new insights into molecular "crosstalk" in pancreas cancer cells, identifying vulnerabilities that could provide a target for therapeutic drugs already being studied in several cancers.

12 Jan 2022

New technique could allow more diseases to be safely treated by nanomedicine

Researchers at Penn Medicine have discovered a new, more effective method of preventing the body's own proteins from treating nanomedicines like foreign invaders, by covering the nanoparticles with a coating to suppress the immune response that dampens the therapy's effectiveness.

11 Jan 2022

Novel mechanism linking intercellular adhesion molecule with genetic skin diseases discovered

Northwestern Medicine investigators have discovered a novel mechanism linking an intercellular adhesion molecule with genetic inflammatory skin diseases, according to findings published in the Journal of Clinical Investigation.

11 Jan 2022

New neural circuits regulating spatial learning, memory in the brain's hippocampal formation discovered

A research team led by University of California, Irvine has discovered new neural circuits that regulate spatial learning and memory in the brain's hippocampal formation.

10 Jan 2022

New appropriate use criteria for prostate-specific membrane antigen PET imaging published

The Society of Nuclear Medicine and Molecular Imaging and peer medical groups have issued appropriate use criteria (AUC) for prostate-specific membrane antigen (PSMA) PET imaging.

7 Jan 2022

World renowned medical oncologist joins Henry Ford Cancer Institute

Internationally renowned medical oncologist Philip A. Philip, M.D., Ph.D., has joined Henry Ford Cancer Institute as director of Gastrointestinal Oncology and Neuroendocrine Oncology, medical director of Research and Clinical Care Integration, and co-leader of the Henry Ford Pancreatic Cancer Center.

6 Jan 2022