Pharmacology

Pharmacology is the study of how chemical substances interact with living systems. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties, interactions, toxicology, therapy, and medical applications and antipathogenic capabilities.

Pharmacology

Pharmacology is the study of the action of drugs on a biologic system. It incorporates components of medicine and biology, and how they interact with each other.

What is in Silico?

What is Drug Absorption?

Drug Distribution

Drug Excretion / Elimination

Drug Metabolism

Pharmacokinetics

What is Psychopharmacology?

Psychopharmacology and Neuropsychopharmacology Research

What is Pharmacoepidemiology?

What is Neuropharmacology?

Metabolomics in Pharmacology

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Importance of Allostery in Pharmacology

Importance of Pharmacology in Dentistry

Pharmacist Career

What is Quantitative Systems Pharmacology (QSP) Modeling?

What is a Dose-Response Curve?

Latest Pharmacology News and Research

Neuroscientists discover a key piece of the placebo effect puzzle

The placebo effect is very real. This we've known for decades, as seen in real-life observations and the best double-blinded randomized clinical trials researchers have devised for many diseases and conditions, especially pain.

24 Jul 2024

Metrion Biosciences appoints Dr Chris Mathes as Chief Commercial Officer

Metrion Biosciences Ltd (“Metrion”), the specialist preclinical contract research organization (CRO) and a leader in ion channel screening, today announced the appointment of Dr Chris Mathes, MBA, as Chief Commercial Officer (CCO). Chris will work alongside the Company’s expert leadership team to drive commercial strategy and lead global business development and marketing activities.

24 Jul 2024

New study sheds light on irregular heartbeat risk

Two new, basic animal research studies shed light on alcohol consumption and the heart. The first study may help explain why binge drinking sometimes causes an irregular heartbeat and a possible way to prevent it. The second study investigated why alcohol may have a negative impact on heart function in women taking estrogen replacement therapy.

23 Jul 2024

Combination therapy incorporating three existing drugs shows potential for treating retinal degenerations

Drug repurposing shows promise in the treatment of retinal degenerations, according to a new study by an international team of researchers, published in Nature Communications.

22 Jul 2024

Unexpected T-cell reactions to adenoviral COVID-19 vaccines discovered

Researchers from the University of Liverpool's Centre for Drug Safety Science have identified unpredicted T-cell immune responses to the adenoviral (Oxford/AstraZeneca and Janssen) COVID-19 vaccines, but not to the mRNA vaccines.

19 Jul 2024

Ginseng genome unlocks secrets of medicinal benefits

A landmark study has successfully decoded the complete ginseng genome, unveiling the genetic mechanisms that govern saponin biosynthesis. This detailed genetic map illuminates the evolutionary and metabolic pathways of Panax ginseng, a staple in traditional medicine. This pivotal discovery promises to drive forward breeding initiatives and augment the plant's medicinal qualities, unlocking new possibilities for therapeutic applications.

19 Jul 2024

New drugs show promise in shrinking breast cancer brain metastases

Researchers from Drexel's College of Medicine have identified new drugs that show early success in shrinking breast cancer tumors that have metastasized in the brain.

18 Jul 2024

Study identifies a new way to make opioids safer

Researchers at the University of Arizona Health Sciences identified a new way to make opioids safer, increasing the pain-relieving properties of opioids while decreasing unwanted side effects through the spinal inhibition of a Heat shock protein 90 isoform.

17 Jul 2024

Early adult weight gain linked to poor heart health in later life, study finds

People who gain excess weight from their 20s onwards have less healthy hearts by the time they are in their 60s, according to research published in the European Heart Journal today (Wednesday).

16 Jul 2024

Researchers reveal unique characteristics of previously unexplored protein FAM110A

An international research collaboration, led by Prof. Dr. Robert Grosse (Centre for Integrative Biological Signalling Studies and Institute of Clinical and Experimental Pharmacology and Toxicology, University of Freiburg), Dr. Libor Macurek (Institute of Molecular Genetics, Czech Academy of Sciences, Prague) and Dr. Zdenek Lansky (Institute of Biotechnology, Czech Academy of Sciences, Prague) has uncovered a new mechanism of the crosstalk between microtubules and actin cytoskeleton during cell division and revealed unique characteristics of the previously unexplored protein FAM110A.

16 Jul 2024

Scientists solve long-standing puzzle about how breastfeeding women's bones remain strong

Researchers at UCSF and UC Davis solved a long-standing puzzle on how the bones of breastfeeding women stay strong even as they lose calcium to milk.

11 Jul 2024

Existing drug shows promise for treating common liver disease

The University of Barcelona has led a study that suggests using the drug known as pemafibrate to treat liver disease associated with metabolic disorders, the most common liver pathology in the world, which affects one in four people. The drug has long been marketed in Japan for another use: improving blood lipid levels in patients with hyperlipidaemia, a common condition in diabetics. Now, however, it could help address this serious liver disease, which still has no specific treatment.

11 Jul 2024

Repurposing pemafibrate to treat liver disease associated with metabolic disorders

10 Jul 2024

Plant-derived substance shows promise against pulmonary hypertension

A substance derived from the plant Ardisia crenata works in a different way than existing drugs. And in doing so, it is highly effective.

8 Jul 2024

Researchers identify potential drugs that make naloxone more potent and longer lasting

The ongoing opioid epidemic in the U.S. kills tens of thousands of people every year. Naloxone, sold under the brand name Narcan, has saved countless lives by reversing opioid overdoses.

3 Jul 2024

New insights into brain energy metabolism may lead to neurodegenerative disease therapies

A key mechanism which detects when the brain needs an additional energy boost to support its activity has been identified in a study in mice and cells led by UCL scientists.

3 Jul 2024

Study finds promising new target for the treatment of Alzheimer's disease

A class of proteins that regulates cell repair and enhances cell growth-signaling systems could be a promising new target for the treatment of Alzheimer's and other neurodegenerative diseases, according to a new study led by researchers at Penn State.

2 Jul 2024

Implementing patient-centered palliative care may help improve quality of life for people with heart disease

Implementing patient-centered palliative care therapies, including prescribing, adjusting or discontinuing medications as needed, may help control symptoms and improve quality of life for people with heart disease, according to "Palliative Pharmacotherapy for Cardiovascular Disease," a new scientific statement from the American Heart Association, published today in the Association's journal, Circulation: Cardiovascular Quality and Outcomes.

1 Jul 2024

MPA-CF3: A marine-derived compound disrupting COPZ1 to combat EV-A71

This study is spearheaded by researcher Wu Zhong (National Engineering Research Center for the Emergence Drugs, Beijing Institute of Pharmacology and Toxicology, Beijing) and Prof. Yong Qin (West China School of Pharmacy, Sichuan University).

26 Jun 2024

Plant-based meat substitutes show promise for heart health

Even though there is substantial variability in the contents and nutritional profiles of plant-based meat alternatives (PBMAs), the nutritional profiles tend to reflect a heart-healthy dietary pattern.

26 Jun 2024