Pharmacology News and Research

Latest Pharmacology News and Research

UH researcher aims to revolutionize treatment regimens for triple-negative breast cancer

A researcher at the University of Houston College of Pharmacy Drug Discovery Institute is working to revolutionize treatment regimens for triple-negative breast cancer (TNBC) by proving that nebivolol, an FDA-approved drug for high blood pressure, is effective in treating it.

31 Jan 2024

Female sex hormone estradiol makes women more susceptible to cocaine addiction

Previous studies focused on cocaine use have found that women are more likely than men to develop an addiction, try cocaine at a younger age, use larger amounts of the drug, and suffer from overdose.

30 Jan 2024

Using AI to break the opioid addiction cycle

When Ben Brown, research assistant professor of chemistry, thinks about the opioid epidemic, he views the problem on a molecular level.

19 Jan 2024

UNC scientists develop "smart" patch for precision drug delivery

University of North Carolina at Chapel Hill scientists created a new drug delivery system, called the Spatiotemporal On-Demand Patch (SOP), which can receive commands wirelessly from a smartphone or computer to schedule and trigger the release of drugs from individual microneedles.

18 Jan 2024

Understanding antimicrobial resistance in hospital-acquired pneumonia

New research has been published that identifies positive steps towards a better understanding of antimicrobial resistance (AMR), specifically in hospital-acquired pneumonia (HAP).

18 Jan 2024

Natural PLA2 inhibitor from marine fungus combats fatty liver disease by silencing lipotoxic pathways

This new article publication from Acta Pharmaceutica Sinica B, discusses the identification of a natural PLA2 inhibitor from the marine fungus Aspergillus sp. c1 for MAFLD treatment that suppressed lipotoxicity by inhibiting the IRE-1α/XBP-1s axis and JNK signaling.

16 Jan 2024

10 years of University of Kentucky's Healthy Hearts for Women takes aim at heart disease

The University of Kentucky will mark a decade of raising awareness and continuing its effort to warn women about the dangers of heart disease with the annual Healthy Hearts for Women Symposium.

12 Jan 2024

Research reveals the function of a little-understood junction between brain cells

New research from Oregon Health & Science University for the first time reveals the function of a little-understood junction between cells in the brain that could have important treatment implications for conditions ranging from multiple sclerosis to Alzheimer's disease, to a type of brain cancer known as glioma.

12 Jan 2024

FluidForm Bio achieves breakthrough in building human cardiac tissues with FRESH 3D bioprinting

FluidForm Bio, a leader in developing life-like human tissue to treat disease, shares recent advancements in building human cardiac tissues using FRESH™ 3D bioprinting.

From FluidForm Bio™ 11 Jan 2024

FluidForm Bio successfully demonstrates advancements in engineered heart tissues with FRESH™ 3D bioprinting

FluidForm Bio, a leader in developing life-like human tissue to treat disease, shares recent advancements in building human cardiac tissues using FRESH™ 3D bioprinting.

From FluidForm Bio™ 11 Jan 2024

IKAROS: Unlocking the secrets of the immune system's key player

In a scientific breakthrough that aids our understanding of the internal wiring of immune cells, researchers at Monash University in Australia have cracked the code behind IKAROS, an essential protein for immune cell development and protection against pathogens and cancer.

5 Jan 2024

Unmasking the persistent threats of long-COVID's pulmonary sequelae

A collaborative study led by Dr. Estefanía Nova-Lamperti of the Universidad de Concepción, Dr. Gonzalo Labarca of Harvard University, and Mauricio Hernández, of MELISA Institute, and which included the participation of researchers from leading academic institutions, sought to identify the sequelae associated with long-term pulmonary dysfunction (L-PDD) in patients with COVID-19.

4 Jan 2024

Researchers uncover variations in how IBD affects people of different races, sexes and places of birth

Researchers from Rutgers and other institutions have uncovered significant variations in how inflammatory bowel disease (IBD) affects people of different races, sexes and places of birth.

3 Jan 2024

Mount Sinai study provides a mechanistic explanation for variations in individual responses to drugs

Mount Sinai researchers have shown for the first time that a person's beliefs related to drugs can influence their own brain activity and behavioral responses in a way comparable to the dose-dependent effects of pharmacology.

3 Jan 2024

Yale scientists identify drug target that may alleviate joint degeneration in osteoarthritis

Yale researchers have identified a drug target that may alleviate joint degeneration associated with osteoarthritis, a debilitating condition that afflicts as many as 30 million people in the United States alone, which they report on Jan. 3 in the journal Nature.

3 Jan 2024

Calcium channel blockers reverse muscle weakness in animal model of myotonic dystrophy type 1

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these symptoms in animal models of the disease.

2 Jan 2024

Brain receptor discovery opens door to new therapies for addiction and mental health

Researchers at the Icahn School of Medicine at Mount Sinai have uncovered insights into the potential mechanism of action of the antipsychotic medication asenapine, a possible therapeutic target for substance use and neuropsychiatric disorders.

2 Jan 2024

St. Jude researchers crack the code of the β2-adrenergic receptor

Through an international collaboration, scientists at St. Jude Children's Research Hospital leveraged data science, pharmacology and structural information to conduct an atomic-level investigation into how each amino acid in the receptor that binds adrenaline contributes to receptor activity in the presence of this natural ligand.

22 Dec 2023

Novel adaptations and functions of human LINE-1 revealed by structural analysis and inhibition

Martin Taylor, MD, PhD, a physician investigator in the Department of Pathology at Massachusetts General Hospital and an instructor in Pathology at Harvard Medical School, is the lead corresponding author of a new study in Nature, Structural Analysis and Inhibition of Human LINE-1 ORF2 Protein Reveals Novel Adaptations and Functions.

19 Dec 2023

Scientists design non-hallucinogenic psychedelic treatments potentially accelerating research on mental health benefits

Researchers identified 5-hydroxytryptamine 2A (5-HT2A) receptor (5-HT2AR) signaling pathways associated with psychedelic potential.

19 Dec 2023

Pharmacology News and Research

Latest Pharmacology News and Research

UH researcher aims to revolutionize treatment regimens for triple-negative breast cancer

Female sex hormone estradiol makes women more susceptible to cocaine addiction

Using AI to break the opioid addiction cycle

UNC scientists develop "smart" patch for precision drug delivery

Understanding antimicrobial resistance in hospital-acquired pneumonia

Natural PLA2 inhibitor from marine fungus combats fatty liver disease by silencing lipotoxic pathways

10 years of University of Kentucky's Healthy Hearts for Women takes aim at heart disease

Research reveals the function of a little-understood junction between brain cells

FluidForm Bio achieves breakthrough in building human cardiac tissues with FRESH 3D bioprinting

FluidForm Bio successfully demonstrates advancements in engineered heart tissues with FRESH™ 3D bioprinting

IKAROS: Unlocking the secrets of the immune system's key player

Unmasking the persistent threats of long-COVID's pulmonary sequelae

Researchers uncover variations in how IBD affects people of different races, sexes and places of birth

Mount Sinai study provides a mechanistic explanation for variations in individual responses to drugs

Yale scientists identify drug target that may alleviate joint degeneration in osteoarthritis

Calcium channel blockers reverse muscle weakness in animal model of myotonic dystrophy type 1

Brain receptor discovery opens door to new therapies for addiction and mental health

St. Jude researchers crack the code of the β2-adrenergic receptor

Novel adaptations and functions of human LINE-1 revealed by structural analysis and inhibition

Scientists design non-hallucinogenic psychedelic treatments potentially accelerating research on mental health benefits

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Pharmacology News and Research

Latest Pharmacology News and Research

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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