Pharmacology News and Research

Latest Pharmacology News and Research

Pharmacogenomic testing could help reduce adverse drug reactions in the UK

A new study from Queen Mary University of London found that 9% of all reported adverse drug reactions (ADRs) reported to the UK medicines regulator are associated with medications where side effect risk is partly dependent on patient's genes.

27 Mar 2025

Study uncovers protective mechanism of BRCA2 in cancer treatment

Mutations in BRCA2 — a gene known to repair damaged DNA and suppress tumor formation — can predict an individuals' predisposition to develop breast cancer, ovarian, prostate, pancreatic, and other epithelial tumors.

26 Mar 2025

Breakthrough DNA delivery system could revolutionize chronic disease treatment

A breakthrough in safely delivering therapeutic DNA to cells could transform treatment for millions suffering from common chronic diseases like heart disease, diabetes, and cancer.

25 Mar 2025

Anti-inflammatory drugs may reduce metabolic disease risk by inhibiting the sweet taste receptor

Past studies have shown that the human sweet taste receptor conveys sweet perception in the mouth and may help regulate glucose metabolism throughout the body.

25 Mar 2025

Cryptotanshinone could be a promising therapeutic option for Kawasaki disease

Announcing a new publication for Acta Materia Medica journal. Kawasaki disease (KD) is a form of vasculitis that affects primarily children and can lead to severe cardiovascular complications.

25 Mar 2025

Blood test shows high accuracy in detecting Alzheimer's in Asian populations

A study in Alzheimer's & Dementia, a leading journal in dementia research, has demonstrated the high accuracy of plasma p-tau217 as a blood-based biomarker for detecting abnormal brain beta-amyloid (Aβ) pathology, a hallmark of Alzheimer's disease (AD).

25 Mar 2025

Fatty acids in the blood may predict risk of developing schizophrenia from cannabis use

The UPV/EHU study, recently published in the journal Scientific Reports, has analyzed and compared the fatty acids in the blood of individuals with schizophrenia, of those with cannabis use disorder and of those with both diagnoses, with the aim of shedding light on new biomarkers and improving the understanding of the biological relationship between the two disorders.

21 Mar 2025

A versatile toolbox sets gold standard for characterizing IRES activity in cells

Only recently has the ribosome - one of the oldest molecular machines in evolutionary terms - been recognized as an active regulator of gene expression at the level of protein biosynthesis.

20 Mar 2025

Coalition of experts reaffirms vaccines as essential for public health

In response to growing concerns over vaccine misinformation, declining public trust in science, and recent outbreaks of preventable diseases, a coalition of 34 scientific and medical organizations, led by the American Association of Immunologists (AAI) and the American College of Physicians (ACP), has issued a unified statement emphasizing the critical role of vaccinations in public health.

18 Mar 2025

Tunneling Nanotube-Like Structures found to play a critical role in heart formation

From his lab at the University of Houston College of Pharmacy Drug Discovery Institute, Mingfu Wu, associate professor, is offering new hope for treating heart disease by sharing his insights into the fundamental process of how the heart is formed in utero.

17 Mar 2025

New insights into ADAR1 mechanisms could revolutionize autoimmune and cancer therapies

A research team led by Rice University's Yang Gao has uncovered new insights into the molecular mechanisms of ADAR1, a protein that regulates ribonucleic acid (RNA) induced immune responses.

17 Mar 2025

Experts release new guidelines on JAK inhibitors for chronic inflammatory diseases

Janus kinase inhibitors (JAKis) are an important treatment option for people with chronic inflammatory diseases such as rheumatoid arthritis, psoriasis, Crohn's disease or ulcerative colitis.

17 Mar 2025

Scientist whose work led FDA to ban food dye says agency overstated risk

When the FDA announced in January, before President Joe Biden's term ended, that it would ban a dye called red dye No. 3 in food and ingested drugs, the federal agency cited just one 1987 study on rats to support its action.

17 Mar 2025

Nanogels can improve antibiotic delivery for urinary tract infections

Researchers from the University of Colorado Anschutz Medical Campus studied a new method to deliver antibiotics, specifically gentamicin, directly into the bladder tissue to better treat UTIs.

12 Mar 2025

Breakthrough drug combination targets KRAS mutation in lung cancer

A breakthrough in lung cancer treatment may be on the horizon. Scientists at VCU Massey Comprehensive Cancer Center have uncovered a powerful combination therapy leveraging sotorasib-an FDA-approved drug in the market-and an experimental drug called FGTI-2734, which could make precision medicine more effective for patients with a highly resistant form of lung cancer.

10 Mar 2025

Diabetes changes the biology of breast cancer, study shows

More than 120 million Americans suffer from diabetes or pre-diabetes. Triple-negative breast cancer (TNBC) is the most aggressive form of breast cancer, and TNBC patients with obesity-driven diabetes often have worse outcomes.

6 Mar 2025

Melatonin protects skeletal muscle from damage caused by "diabesity"

An international study led by the University of Granada (UGR) has revealed that melatonin, known for its ability to regulate the sleep/wake cycle, can restore the composition of muscle fibers and protect skeletal muscle from damage caused by obesity and type 2 diabetes, known as "diabesity".

5 Mar 2025

New three-organ system offers an animal-free alternative for pharmacokinetics research

Innovative organ-on-chip specialist Dynamic42 and ESQlabs, experts in digital life sciences solutions, have successfully developed a three-organ system, in close collaboration with Consumer Health Division of Bayer, and the Placenta Lab at Jena University Hospital.

2 Mar 2025

Scientists develop fenugreek-based nanoparticles to enhance diabetes drug effectiveness

Researchers explored L-arginine-loaded lipid nanoparticles from fenugreek seed oil, finding they enhance drug stability and bioavailability, showing promise for diabetes treatment.

2 Mar 2025

New study identifies brain circuit key to reducing cocaine-seeking behavior

Imagine a future where the grip of cocaine use disorder can be loosened, where cravings fade, and the risk of relapse diminishes.

27 Feb 2025

Pharmacology News and Research

Latest Pharmacology News and Research

Pharmacogenomic testing could help reduce adverse drug reactions in the UK

Study uncovers protective mechanism of BRCA2 in cancer treatment

Breakthrough DNA delivery system could revolutionize chronic disease treatment

Anti-inflammatory drugs may reduce metabolic disease risk by inhibiting the sweet taste receptor

Cryptotanshinone could be a promising therapeutic option for Kawasaki disease

Blood test shows high accuracy in detecting Alzheimer's in Asian populations

Fatty acids in the blood may predict risk of developing schizophrenia from cannabis use

A versatile toolbox sets gold standard for characterizing IRES activity in cells

Coalition of experts reaffirms vaccines as essential for public health

Tunneling Nanotube-Like Structures found to play a critical role in heart formation

New insights into ADAR1 mechanisms could revolutionize autoimmune and cancer therapies

Experts release new guidelines on JAK inhibitors for chronic inflammatory diseases

Scientist whose work led FDA to ban food dye says agency overstated risk

Nanogels can improve antibiotic delivery for urinary tract infections

Breakthrough drug combination targets KRAS mutation in lung cancer

Diabetes changes the biology of breast cancer, study shows

Melatonin protects skeletal muscle from damage caused by "diabesity"

New three-organ system offers an animal-free alternative for pharmacokinetics research

Scientists develop fenugreek-based nanoparticles to enhance diabetes drug effectiveness

New study identifies brain circuit key to reducing cocaine-seeking behavior

Pittcon Highlights: Pharmaceutical & Biologic eBook

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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