Pharmacology News and Research

Latest Pharmacology News and Research

New immunotherapeutic platform improves mRNA therapy efficacy against cancer

Therapeutic mRNAs offer great potential as a versatile and precise tool against cancer and other diseases.

9 Dec 2024

Engineered immune cells could transform treatment for autoimmune diseases

Immune cells that are designed to soothe could improve treatment for organ transplants, type 1 diabetes and other autoimmune conditions.

9 Dec 2024

New technology guides immune cells to fight brain cancer and multiple sclerosis

Researchers have found a way to program immune cells to attack glioblastoma and treat the inflammation of multiple sclerosis in mice.

6 Dec 2024

Study: Brain volume changes correlate with social behavior differences in psychiatric conditions

A study published in Molecular Psychiatry found that brain volume changes correlate with social behavior differences in psychiatric conditions such as autism spectrum disorder and schizophrenia.

6 Dec 2024

EZH2 inhibitors enhance effectiveness of cancer immunotherapies

An emerging class of anticancer drugs called EZH2 inhibitors may greatly enhance the potency of some cancer immunotherapies, according to a preclinical study led by Weill Cornell Medicine lymphoma researchers.

5 Dec 2024

Discovery of leptin-responsive neurons offers new hope for obesity treatment

Obesity affects a staggering 40 percent of adults and 20 percent of children in the United States. While some new popular therapies are helping to tackle the epidemic of obesity, there is still so much that researchers do not understand about the brain-body connection that regulates appetite.

5 Dec 2024

Study challenges long-standing understanding of axon structure

Biology textbooks may need a revision, say Johns Hopkins Medicine scientists, who present new evidence that an armlike structure of mammalian brain cells may be a different shape than scientists have assumed for more than a century.

2 Dec 2024

Study reveals effects of temporary blood flow loss on blood vessels in hypertensive rats

A study coordinated by Dr Francesc Jiménez-Altayó, researcher at the Institut de Neurociències of the UAB (INc-UAB) and at CIBERCV, shows that temporary lack of blood flow to the brain can lead to lasting changes in the small arteries of the abdomen in rats with high blood pressure.

28 Nov 2024

Revolutionary strategy offers hope for type 1 diabetes treatment

Regenerative medicine holds the extraordinary promise that future patients in need of new cells, tissues or organs will no longer have to rely on donors. Organ shortages and cell type mismatches will become past problems, replaced by safe, on-demand options for anyone who needs a transplant.

25 Nov 2024

Researchers discover key protein interaction driving skin cancer growth

LMU researchers have discovered how the interplay between a key protein and an endolysosomal ion channel promotes tumor development in skin cancer.

22 Nov 2024

New study unveils why glioblastoma becomes resistant to treatment

A new study from scientists at the UCLA Health Jonsson Comprehensive Cancer Center helps explain why glioblastoma, one of the most aggressive forms of brain cancer, becomes resistant to treatment, and introduces a new approach that paves the way for more personalized treatment strategies for patients with this deadly brain tumor.

22 Nov 2024

Vanderbilt receives $3.3 million grant to develop medications for preventing preterm birth

Vanderbilt University Medical Center is receiving $3.3 million over two years through the Advanced Research Projects Agency for Health's (ARPA-H) Sprint for Women's Health for its early-stage research efforts to develop medications designed to suppress premature uterine contractions during pregnancy.

15 Nov 2024

FasL inhibitor speeds recovery and reduces mortality in severe COVID-19 patients

A new clinical study shows that an inhibitor of Fas ligand (FasL), also called CD95 ligand (CD95L), led to a faster recovery of COVID-19 patients and reduced mortality.

14 Nov 2024

Scientists discover new breakthrough in weight loss and diabetes treatment

Scientists at the University of Copenhagen have discovered a new weight loss drug target that reduces appetite, increases energy expenditure, and improves insulin sensitivity without causing nausea or loss of muscle mass.

13 Nov 2024

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Professor Nancy Ip discusses her groundbreaking neuroscience research, focusing on neurotrophic factors and innovative Alzheimer's disease treatment approaches.

13 Nov 2024

Targeted degradation of Pin1 shows promise for pancreatic cancer treatment

In drug discovery, targeted protein degradation is a method that selectively eliminates disease-causing proteins.

11 Nov 2024

Research reveals how caterpillar fungus chemical may treat cancer

New research into a chemical produced by a caterpillar fungus that has shown promise as a possible cancer treatment has revealed how it interacts with genes to interrupt cell growth signals.

7 Nov 2024

Rice bioengineers uncover why IL-12 immunotherapy loses effectiveness

A team of Rice University bioengineers has developed a mathematical model that clarifies why interleukin-12 (IL-12) ⎯ a potent immune-boosting protein that holds promise for cancer treatment ⎯ loses effectiveness over time when used as an immunotherapeutic.

6 Nov 2024

New technology for visualizing AMPA receptors offers insights into psychiatric disorders

Even though psychiatric disorders such as schizophrenia, bipolar disorder, and autism spectrum disorder (ASD) are quite common, their diagnosis and treatment are challenging.

5 Nov 2024

Huntington’s disease symptoms reduced by new peptide-polymer therapy

Scientists at Northwestern and Case Western Reserve universities have developed the first polymer-based therapeutic for Huntington's disease, an incurable, debilitating illness that causes nerve cells to break down in the brain.

3 Nov 2024