Pharmacology News and Research

Latest Pharmacology News and Research

Obesity disrupts ILC2 metabolism through increased fatty acid uptake

A group of innate immune cells, known as group 2 lymphoid cells (ILC2), are essential for maintaining a stable metabolism in adipose tissue. Obesity significantly impairs the number and function of ILC2 cells, leading to the progression of metabolism-related inflammation.

23 Sep 2026

Screening approved medicines reveals potential treatments for preterm labor

Shajila Siricilla, PhD, Assistant Professor of Pediatrics, and Jennifer Herington, PhD, Associate Professor of Pediatrics, led a team that systematically screened 1,191 FDA-approved drugs and found that several candidates met criteria supporting further evaluation as potential treatments for preterm labor.

23 Sep 2026

Early childhood BMI trajectories predict later cardiometabolic health risks

Childhood obesity predicts later cardiometabolic disease, but single-time weight measures may miss dynamic growth information.

23 Sep 2026

Waist-to-height ratio reliably detects chronic liver disease risk in children

Metabolic dysfunction-associated steatotic liver disease (MASLD) is now the most common chronic liver disease in children and adolescents, closely mirroring the global rise in childhood obesity.

22 Sep 2026

Researchers create virtual cells to accelerate drug discovery efforts

Mitochondria - tiny structures that convert nutrients into energy - are often depicted as discrete kidney bean-shaped objects.

18 Sep 2026

Eight-weekly HIV injections prove more effective than daily tablets for young people

Young people living with HIV manage their condition better when their antiretroviral therapy is given by injections every eight weeks, rather than in the form of daily tablets, according to the results of a trial in Africa led by UCL (University College London) researchers.

17 Sep 2026

Shatavari may affect more than hormones, and the gut could help explain why

A review in Nutrients examined how bioactive compounds in Asparagus racemosus (Shatavari) may influence cognitive health through the microbiota-gut-brain axis, estrogen-related signaling, neuroinflammation, oxidative stress, and neurotransmitter regulation. Evidence from computational, cellular, animal, and limited human studies suggests several plausible biological pathways, but key questions remain about bioavailability, brain exposure, dosing, and clinical efficacy.

16 Sep 2026

Targeted antibody therapy provides long-lasting relief from neuropathic pain

Pain is a natural protective mechanism that alerts the body to actual or potential injury. But when nerves themselves are damaged, they can generate abnormal pain signals even in the absence of a new injury.

16 Sep 2026

Common medications trigger potentially harmful prescribing cascades in older adults

A new Ontario-wide study reveals that common medications, from statins to iron supplements, are quietly setting off prescribing cascades that leave older adults unknowingly taking drugs to treat side effects of other drugs.

10 Sep 2026

GLP-1 treatment linked to 40% fewer asthma attacks

The diabetes and weight loss injection semaglutide can reduce asthma attacks by up to 40 per cent according to research presented at the European Respiratory Society (ERS) Congress in Barcelona, Spain.

7 Sep 2026

Younger and older brains respond differently to traumatic injury

Conventional wisdom holds that younger brains are better equipped to recover from injury. Their greater flexibility allows them to adapt, rebuild connections and compensate for damage in ways older brains often cannot.

4 Sep 2026

Targeting KV7 proteins could help delay preterm labor

Scientists have found that targeting a particular group of proteins in the uterus muscle (myometrium) can suppress human uterine contractions in laboratory studies and delay preterm birth in a preclinical model.

3 Sep 2026

Plyo-HIIT program targets healthier body composition in children

Traditional weight-loss strategies for children, from calorie restriction to general aerobic exercise, often carry an unwanted side effect: they cut fat, but they also erode muscle mass.

28 Aug 2026

Updated consensus offers new roadmap for childhood bedwetting care

Nocturnal enuresis (NE) in school-age children is more than a nighttime inconvenience: when persistent, it can affect self-esteem, sleep, family life and social functioning.

28 Aug 2026

CAR T-cell therapy successfully reverses severe rheumatoid arthritis

Immunotherapies such as CAR T-cell therapy are used primarily to treat cancer. In the future, these patient-specific therapies, manufactured from patients' own immune cells, could also help cure autoimmune diseases.

27 Aug 2026

UofL receives new federal funding to advance metabolic health research

Chronic health conditions such as diabetes, obesity, heart disease and metabolic liver disease have sharply increased in recent decades and are among the most urgent health challenges facing our society.

27 Aug 2026

Scientists discover how neutrophils travel to infection sites without damaging healthy tissue

UMass Chan Medical School scientist Beth McCormick, PhD, and her team collaborated with researchers at the University of Bath to discover how neutrophils, the body's most abundant type of white blood cells, travel to infection sites without damaging healthy tissue.

25 Aug 2026