Pharmacology News and Research

Latest Pharmacology News and Research

Lactate and lactylation play multifaceted roles in pancreatic ductal adenocarcinoma

A comprehensive review recently published in Current Molecular Pharmacology illuminates the pivotal, multifaceted roles of lactate and its downstream protein modification, lactylation, in pancreatic ductal adenocarcinoma (PDAC).

25 Jun 2026

Study uncovers mechanism driving metastasis in aggressive gastric cancer

A study recently published in Current Molecular Pharmacology has uncovered a novel mechanism by which the long non‑coding RNA PVT1 and the translation initiation factor EIF4A1 cooperate to drive gastric cancer metastasis.

25 Jun 2026

Natural bioactive compounds target miR-29a molecule to prevent cancer development

A study published in Current Molecular Pharmacology provides a comprehensive analysis of microRNA-29a (miR-29a) as a pivotal regulator in cancer development, and examines how natural bioactive compounds may offer a promising strategy for cancer prevention by modulating its expression.

25 Jun 2026

Study identifies fPRDM16 as target for age-related pulmonary fibrosis

A study published recently in Current Molecular Pharmacology has uncovered a key mechanism linking aging to persistent pulmonary fibrosis, identifying the transcriptional regulator fPRDM16 as a potential therapeutic target.

25 Jun 2026

New review highlights TREM-1 receptor as target for inflammatory diseases

A comprehensive review recently published in Current Molecular Pharmacology consolidates the growing evidence surrounding the Triggering Receptor Expressed on Myeloid Cells-1 (TREM-1) as a central amplifier of innate immune responses and a promising therapeutic target for a range of inflammatory diseases.

25 Jun 2026

Targeted investments can significantly reduce newborn deaths by 2040

A global analysis spanning 194 countries reveals a mixed picture for newborn survival: deaths caused by birth asphyxia, trauma, and prematurity have declined markedly since 2000, yet progress is slowing in many low- and middle-income countries, particularly across sub-Saharan Africa.

25 Jun 2026

Study uncovers sex-specific immune pathway driving glioblastoma growth

Researchers have identified a critical biological difference in how glioblastoma develops in male and female laboratory models, pinpointing an immune pathway that fuels tumor growth only in females.

23 Jun 2026

Early screen time may impact subsequent academic performance and working memory

The World Health Organization (WHO) and the American Academy of Pediatrics recommend no screen time before 18-24 months and less than one hour per day for children ages 2 to 5.

22 Jun 2026

Sugary chewing gum may temporarily enhance beetroot's blood pressure benefits

For the first time, researchers at King's College London have discovered a link between chewing sugary gum after consuming vegetables high in nitrate, such as beetroot, spinach and kale, on lowering blood pressure.

18 Jun 2026

Single-dose gene therapy extends healthy lifespan in older mice

A research team from the Universitat Autònoma de Barcelona (UAB) has shown that a one-time administration of a gene therapy expressing the metabolic factor FGF21 can prolong health span in old mice.

15 Jun 2026

Saliva biomarkers can directly detect acute sleep deprivation

A research team at the University of Zurich (UZH) has discovered biomarkers of sleep loss in saliva. Acute sleep deprivation can be detected using just a single saliva sample.

12 Jun 2026

Realistic cellular conditions revive previously dismissed drug candidates

A drug once dismissed as ineffective suddenly worked - when scientists tested it under more realistic conditions that mimic the human body.

9 Jun 2026

New geroscience initiative aims to accelerate anti‑aging therapies

Albert Einstein College of Medicine has launched the Batia and Idan Ofer program for Validation of Interventions Targeting Aging and Longevity (BIO-VITAL), a new initiative designed to help biotechnology and pharmaceutical companies advance therapies that target the biology of aging.

9 Jun 2026

Father's alcohol use before conception impacts offspring development

A growing body of research suggests that a father's health before conception may play a larger role in child development than previously understood - and researchers are working to understand how a father's drinking before conception may affect offspring health and development.

8 Jun 2026

Researchers develop compound 10 to slow Alzheimer's disease progression

Researchers from ETH Zurich have developed an active ingredient that slows down the progression of typical Alzheimer’s symptoms in mice. This new substance protects nerve cells and could in future alleviate the suffering of Alzheimer’s patients. The active ingredient also shows anti-aging effects.

8 Jun 2026

Air pollution below EPA thresholds still poses heart health risks

Air pollution does not have to exceed federal limits to potentially harm human health, according to a new review published in Environmental Pollution.

3 Jun 2026

Study shows how TAF1 regulates ferroptosis in cancer cells

Ferroptosis has become a promising area in cancer research because it may provide a way to target tumor cells that evade other better-known forms of programmed cell death, such as apoptosis and necroptosis.

3 Jun 2026

Acupuncture improves muscle function recovery in stroke patients

Paralysis on one side of the body is common after stroke. A new study in CNS Neuroscience & Therapeutics demonstrates that acupuncture can significantly improve muscle function recovery in patients who experienced a stroke, with this recovery correlating to increases in grey matter volume in certain regions of the brain related to cognitive-motor integration.

3 Jun 2026

New platform identifies barriers to therapeutic antibody delivery in solid tumors

Eben Rosenthal, MD, the Barry and Amy Baker Professor and Chair of the Department of Otolaryngology-Head and Neck Surgery at Vanderbilt Health, is the senior author of the paper. Rosenthal and co-author Guolan Lu, PhD, of Stanford University School of Medicine, developed single-cell spatial pharmacobiology (SSP), an experimental and analytical platform that allows visualization of drug-tumor interactions in human solid tumors.

3 Jun 2026

Post-discharge oral antibiotics show no benefit for pediatric appendicitis

Acute appendicitis is one of the most common surgical emergencies among children, and complicated acute appendicitis (CAA), including perforated or gangrenous disease, carries a higher risk of infection and longer hospitalization.

1 Jun 2026