Pharmacology News and Research

Latest Pharmacology News and Research

Analysis reveals limited evidence on use of cannabis products in children with cancer

A recent analysis of all relevant published studies reveals a lack of evidence to determine the dosing, safety, and efficacy of medical marijuana or cannabis-containing products for managing symptoms experienced by children with cancer.

29 Aug 2023

Cholesterol loss in inner ear linked to age-related hearing loss

Researchers led by María Eugenia Gomez-Casati, the Institute of Pharmacology, School of Medicine, University of Buenos Aires-CONICET; Mauricio Martin, the Institute of Medical Research Mercedes; and Martín Ferreyra, (INIMEC-CONICET-UNC), National University of Córdoba in Argentina report that age-related hearing loss is associated with a decrease of cholesterol in the inner ear.

24 Aug 2023

Neglected brain region could play a critical role in drug relapse

Researchers from Indiana University School of Medicine have discovered a neglected brain region that could play a critical role in how likely a person with drug use disorders is to relapse, even after a long withdrawal period.

24 Aug 2023

Strengthening prison reentry programs can help reduce opioid overdose deaths in the U.S.

With opioid overdose deaths surging in the United States, many communities are in desperate need of solutions to bring down the body count. Among the most promising is strengthening prison reentry programs for highest-risk users, a Rutgers-led study has found.

21 Aug 2023

NIH supports research to understand the genome-metal interactions in nonalcoholic fatty liver disease

Wanqing Liu, Ph.D., professor of pharmaceutical sciences in the Wayne State University Eugene Applebaum College of Pharmacy and Health Sciences and of pharmacology in Wayne State's School of Medicine, received a $3 million, five-year award from the National Institute of Environmental Health Sciences of the National Institutes of Health.

21 Aug 2023

Lorazepam linked to shorter progression-free survival in pancreatic cancer patients

Patients with pancreatic cancer who took the benzodiazepine lorazepam (Ativan), commonly prescribed to treat anxiety during cancer treatment, had a shorter progression-free survival than patients who did not, according to results published in Clinical Cancer Research, a journal of the American Association for Cancer Research (AACR).

17 Aug 2023

Scientist receives $6.8M grant to study how environmental chemicals increase CVD risk

Exposure to environmental chemicals, including those in common plastic products, has been linked with an increased risk of cardiovascular disease, or CVD, the leading cause of death worldwide. According to the World Health Organization, 17.9 million people died from CVDs in 2019.

16 Aug 2023

Scientists capture first images of ribosome-modifying enzymes in action

Bacteria draw from an arsenal of weapons to combat the drugs intended to kill them. Among the most prevalent of these weapons are ribosome-modifying enzymes.

14 Aug 2023

Scientists uncover new molecular targets for cardiovascular regulation

Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States and a leading research center for diabetes and other life-threatening illnesses, have uncovered new molecular targets on a cell receptor that play a major role in cardiovascular regulation.

14 Aug 2023

Illustrating the safety of a new drug treatment designed for spinal cord injury

New orally available drug for spinal cord injury found to be safe and tolerable in healthy participants.

11 Aug 2023

Tiny particles made from red blood cells may treat atherosclerosis and other diseases

Atherosclerosis is a disease in which fat, cholesterol, and other substances build up inside artery walls. This can lead to plaque formation, which can block arteries and cause heart attacks and strokes.

10 Aug 2023

Experimental drug can reduce symptoms of inflammatory bowel disease in pre-clinical models

A new study of mice and lab-grown human colon "organoids" indicates that an experimental drug developed by Johns Hopkins Medicine researchers can substantially reduce symptoms of inflammatory bowel disease (IBD) in pre-clinical models.

10 Aug 2023

Gut microbiome changes have significant effects on cocaine use and cravings

According to the 2021 National Survey on Drug Use and Health, 4.8 million people (ages 12 and up) reported using cocaine within the previous 12 months, and 24,486 people died from an overdose involving cocaine.

3 Aug 2023

Insilico Medicine's new AI tool shows promise in predicting clinical trial outcomes

Insilico Medicine ("Insilico"), a clinical-stage end-to-end generative artificial intelligence (AI) drug discovery company, has demonstrated that it can predict the outcome of Phase II to Phase III clinical trial success using its proprietary transformer-based AI clinical trial prediction tool called inClinico with a high degree of accuracy.

3 Aug 2023

Study reveals two key mechanisms underlying high risks from lung infections in Down syndrome

Individuals with Down syndrome, the genetic condition caused by triplication of human chromosome 21, also known as trisomy 21, display a very high risk of hospitalization and mortality after developing lung infections.

2 Aug 2023

Phase 1 clinical trial underway to test City of Hope-developed cancer treatment

Researchers at City of Hope, one of the largest cancer research and treatment organizations in the United States, today published a new study explaining how they took a protein once thought to be too challenging for targeted therapy, proliferating cell nuclear antigen (PCNA), and developed a targeted chemotherapy that appears to annihilate all solid tumors in preclinical research.

1 Aug 2023

Inflammaging: The hidden cause of aging and age-related conditions

University of Virginia School of Medicine researchers have discovered a key driver of chronic inflammation that accelerates aging.

28 Jul 2023

Scientists unravel step-by-step activation process of protein with deep evolutionary history

Scientists have unraveled the step-by-step activation process of a protein with a deep evolutionary history in all domains of life, opening the door to harnessing its functions for use as a biotechnology tool.

26 Jul 2023

MD Anderson and Nexo Therapeutics partner to advance new cancer therapies against previously undruggable targets

The University of Texas MD Anderson Cancer Center and Nexo Therapeutics today announced a multi-year strategic collaboration that aligns the innovative technology and capabilities of each organization at the earliest stages of drug discovery and development to rapidly advance impactful new cancer therapies against previously undruggable targets.

26 Jul 2023

A novel pharmacology modeling approach to monitor acute lymphoblastic leukemia treatment

This research paper published in Scientific Reports developed pharmacokinetic (PK) pharmacodynamic (PD) models of maintenance therapy for childhood acute lymphoblastic leukemia (ALL).

26 Jul 2023

Pharmacology News and Research

Latest Pharmacology News and Research

Analysis reveals limited evidence on use of cannabis products in children with cancer

Cholesterol loss in inner ear linked to age-related hearing loss

Neglected brain region could play a critical role in drug relapse

Strengthening prison reentry programs can help reduce opioid overdose deaths in the U.S.

NIH supports research to understand the genome-metal interactions in nonalcoholic fatty liver disease

Lorazepam linked to shorter progression-free survival in pancreatic cancer patients

Scientist receives $6.8M grant to study how environmental chemicals increase CVD risk

Scientists capture first images of ribosome-modifying enzymes in action

Scientists uncover new molecular targets for cardiovascular regulation

Illustrating the safety of a new drug treatment designed for spinal cord injury

Tiny particles made from red blood cells may treat atherosclerosis and other diseases

Experimental drug can reduce symptoms of inflammatory bowel disease in pre-clinical models

Gut microbiome changes have significant effects on cocaine use and cravings

Insilico Medicine's new AI tool shows promise in predicting clinical trial outcomes

Study reveals two key mechanisms underlying high risks from lung infections in Down syndrome

Phase 1 clinical trial underway to test City of Hope-developed cancer treatment

Inflammaging: The hidden cause of aging and age-related conditions

Scientists unravel step-by-step activation process of protein with deep evolutionary history

MD Anderson and Nexo Therapeutics partner to advance new cancer therapies against previously undruggable targets

A novel pharmacology modeling approach to monitor acute lymphoblastic leukemia treatment

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

Natural products: the next frontier in drug discovery

Pharmacology News and Research

Latest Pharmacology News and Research

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

Natural products: the next frontier in drug discovery

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