Pneumonia News and Research

Latest Pneumonia News and Research

New scoring system can help clinicians better identify non-ICU patients at risk for GI bleeding

Critically ill patients in hospital intensive care units (ICUs) are routinely prescribed acid-suppressive medications to reduce their risk of developing stress ulcers and gastrointestinal bleeding, both of which can result from being in a stressful environment and from being intubated. Over the years, this routine practice has often been extended to patients outside the ICU, despite a lack of evidence that this population is at significant risk of these complications.

9 Jan 2013

Paratek receives FDA QIDP designation for omadacycline to treat ABSSSI, CABP

Paratek Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) has designated the Company's lead antibiotic candidate, omadacycline (formerly known as PTK 0796), as a Qualified Infectious Disease Product (QIDP) for both intravenous (IV) and oral formulations in the treatment of acute bacterial skin and skin structure infections (ABSSSI) and community-acquired bacterial pneumonia (CABP).

3 Jan 2013

No significant difference in patient outcomes with RBC transfusions using lower threshold levels

The level at which red blood cells are transfused, a common treatment in clinical practice, is often deliberated among physicians. Guidelines for blood transfusion levels were only recently issued in March 2012 diminishing some of the debate. Today, in a new section called JAMA Clinical Evidence Synopsis, the Journal of the American Medical Association (JAMA), published a summary of the systematic review of the 19 clinical trials that compare higher versus lower hemoglobin thresholds in red blood cell transfusion.

3 Jan 2013

New insights into devastating second impact syndrome

Physicians at Indiana University School of Medicine and the Northwest Radiology Network (Indianapolis, Indiana) report the case of a 17-year-old high school football player with second impact syndrome (SIS). A rare and devastating traumatic brain injury, SIS occurs when a person, most often a teenager, sustains a second head injury before recovery from an earlier head injury is complete.

2 Jan 2013

Antibiotics do not help lower-respiratory tract infections

The antibiotic amoxicillin fares no better at reducing symptoms in patients with lower-respiratory tract infections than a placebo drug, indicate data from a dozen European countries.

28 Dec 2012

Genome sequencing may help identify new targets to treat Pneumocystis pneumonia

Scientists have sequenced the genome of the fungus Pneumocystis jirovecii, an advancement that could help identify new targets for drugs to treat and prevent Pneumocystis pneumonia, a common and often deadly infection in immunocompromised patients.

26 Dec 2012

Cause of recurrent infections in MECP2 duplication syndrome identified

US study results show that the genetic abnormality underlying the pediatric condition methyl-CpG binding protein 2 duplication syndrome also causes immune dysfunction.

24 Dec 2012

Genetic innovations for pneumonia diagnosis in children

Polymerase chain reaction could help diagnose Mycoplasmia pneumonia infection in children, researchers say.

24 Dec 2012

Pneumococcal disease risk increased in mental health patients

Patients with severe mental illness are at increased risk for pneumococcal disease, results from a UK study suggest.

22 Dec 2012

Reviewing G-FINDER report findings

Nick Chapman, a policy analyst at Policy Cures, writes in a guest post on the Global Health Technologies Coalition's "Breakthroughs" blog about "the results of the latest G-FINDER survey on global funding of [research and development (R&D)] for neglected diseases."

21 Dec 2012

Antibiotic amoxicillin ineffective for treating cough according to European trial

The antibiotic amoxicillin, that doctors typically prescribe for common lower respiratory tract infections (LRTI) such as cough and bronchitis, is no more effective at relieving symptoms than the use of no medication, even in older patients. The findings from the largest randomised placebo controlled trial of antibiotics for acute uncomplicated LRTI to date are published Online First in The Lancet Infectious Diseases.

20 Dec 2012

Hospitals with good work environment have low readmission rates

New research from the University of Pennsylvania School of Nursing has found that Medicare patients treated in hospitals with a good work environment for nurses had up to ten percent lower odds of readmission than those treated in hospitals with a poor work environment.

20 Dec 2012

Small ceramic indoor cookstoves do not reduce pneumonia incidence among children, study shows

"Small ceramic indoor stoves, such as those sold by women in AIDS self-help groups in Africa, do save fuel and cut down on eye-irritating smoke, a new study has found -- but they do not save children from pneumonia," the New York Times reports.

19 Dec 2012

Strong unadjusted relationship between COPD, pneumonia and lung cancer

Chronic obstructive pulmonary disease (COPD) and lung cancer are two of the most important smoking-related diseases worldwide, with a huge combined mortality bur-den. Many consider the presence of COPD itself to be an independent risk factor for lung cancer. Others argue that smoking contributes to both COPD and lung cancer.

17 Dec 2012

Ibrutinib continues to show unprecedented results in patients with mantle cell lymphoma

An international study of ibrutinib in people with relapsed or refractory mantle cell lymphoma (MCL) continues to show unprecedented and durable results with few side effects.

15 Dec 2012

Cempra commences CEM-102 Phase 2 trial in prosthetic joint infections

Cempra, Inc., a clinical-stage pharmaceutical company focused on developing antibiotics to meet critical medical needs in the treatment of bacterial infectious diseases, today announced the initiation of its Phase 2 clinical trial of CEM-102 in patients with prosthetic joint infections (PJIs).

15 Dec 2012

Study suggests that existing HIV drug could be a potential therapy for Staph infections

A new study by NYU School of Medicine researchers suggests that an existing HIV drug called maraviroc could be a potential therapy for Staphylococcus aureus, a notorious and deadly pathogen linked to hundreds of thousands of hospitalizations each year.

15 Dec 2012

Meridian completes beta trials for two new illumigene molecular amplification tests

Meridian Bioscience, Inc. today announced that it has successfully completed beta trials for two new illumigene molecular amplification tests.

14 Dec 2012

Ceramic cookstoves may not reduce risk of pneumonia in young rural Kenyan children

Inexpensive, locally-produced ceramic cookstoves may produce less smoke than traditional indoor 3-stone firepits, but they don't significantly reduce indoor air pollution or the risk of pneumonia in young children, according to results from a small, year-long observational study by researchers working in rural Kenya.

13 Dec 2012

Interim results from Inspiration’s OBI-1 and IB1001 hemophilia clinical study

Inspiration Biopharmaceuticals, Inc. (Inspiration) announced interim clinical results for the company's two lead product candidates, an intravenous recombinant porcine FVIII (OBI-1) in the treatment of serious bleeds in acquired hemophilia A (AHA) and an intravenous recombinant FIX (IB1001) for the treatment and prevention of bleeding in children less than 12 years of age with hemophilia B.

13 Dec 2012

Pneumonia News and Research

Latest Pneumonia News and Research

New scoring system can help clinicians better identify non-ICU patients at risk for GI bleeding

Paratek receives FDA QIDP designation for omadacycline to treat ABSSSI, CABP

No significant difference in patient outcomes with RBC transfusions using lower threshold levels

New insights into devastating second impact syndrome

Antibiotics do not help lower-respiratory tract infections

Genome sequencing may help identify new targets to treat Pneumocystis pneumonia

Cause of recurrent infections in MECP2 duplication syndrome identified

Genetic innovations for pneumonia diagnosis in children

Pneumococcal disease risk increased in mental health patients

Reviewing G-FINDER report findings

Antibiotic amoxicillin ineffective for treating cough according to European trial

Hospitals with good work environment have low readmission rates

Small ceramic indoor cookstoves do not reduce pneumonia incidence among children, study shows

Strong unadjusted relationship between COPD, pneumonia and lung cancer

Ibrutinib continues to show unprecedented results in patients with mantle cell lymphoma

Cempra commences CEM-102 Phase 2 trial in prosthetic joint infections

Study suggests that existing HIV drug could be a potential therapy for Staph infections

Meridian completes beta trials for two new illumigene molecular amplification tests

Ceramic cookstoves may not reduce risk of pneumonia in young rural Kenyan children

Interim results from Inspiration’s OBI-1 and IB1001 hemophilia clinical study

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Evolving spectrophotometry for modern biopharma workflows

Pneumonia News and Research

Latest Pneumonia News and Research

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Evolving spectrophotometry for modern biopharma workflows

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