Polycystic Kidney Disease News and Research

Latest Polycystic Kidney Disease News and Research

Otsuka obtains regulatory approval in Japan for pharmacological treatment of ADPKD

Otsuka Pharmaceutical Co., Ltd. today announced it has become the first company in the world to obtain regulatory approval for a pharmacological treatment of autosomal dominant polycystic kidney disease (ADPKD). Samsca (generic name: tolvaptan) has been approved in Japan in 7.5-mg and 15-mg tablet forms for extended use for the additional indication of ADPKD. Also, the new dosage form of 30-mg Samsca tablets has received approval for the indication of ADPKD.

24 Mar 2014

Scientists discover that natural product in grapefruit can prevent kidney cysts

Scientists at Royal Holloway, University of London, have discovered that a natural product found in grapefruit can prevent kidney cysts from forming.

13 Mar 2014

Researchers discover protein required for growth of hair-like structures on cell surfaces

A team of researchers from Penn State University and the University of California has discovered a protein that is required for the growth of tiny, but critical, hair-like structures called cilia on cell surfaces.

28 Jan 2014

EMA accepts Otsuka's marketing authorisation application for tolvaptan for treatment of ADPKD

Otsuka Pharmaceutical Co., Ltd. announced today that the European Medicines Agency (EMA) has accepted the submission of a marketing authorisation application (MAA) for the potential approval of tolvaptan for the treatment of autosomal dominant polycystic kidney disease (ADPKD).

27 Dec 2013

Holiday reads: Squabbling families, the psychology of Santa, holiday stress and chocolate chip cookies

[T]his time of year the Internet is ripe with lists on how to avoid or mitigate family conflicts. At big gatherings, familiarity may not always breed contempt, but it sure can breed festering emotional wounds. Leonard Felder, a Los Angeles psychologist, has found that about three-quarters of us have at least one family member who annoys us. But why is it that the same minor jabs and annoying tics that are harmless coming from friends prompt epic screaming matches when uttered by relatives? ... Here are four theories as to why our families drive us nuts, and it would be nice of you to pay attention for once in your life (Olga Khazan, 12/23).

24 Dec 2013

Scientists at Salk Institute develop novel platform to study kidney diseases

Diseases affecting the kidneys represent a major and unsolved health issue worldwide. The kidneys rarely recover function once they are damaged by disease, highlighting the urgent need for better knowledge of kidney development and physiology.

19 Nov 2013

Researchers generate three-dimensional kidney structures from human stem cells

18 Nov 2013

3Sbio acquires patents for DJ5 to delay hereditary renal disease in ADPKD patients

3SBio Inc., a leading China-based biotechnology company focused on researching, developing, manufacturing and marketing biopharmaceutical products, announced the acquisition of patents for DJ5, a novel non-TZD PPARgamma agonist with potential to retard progressive renal failure in patients with autosomal dominant polycystic kidney disease ("ADPKD').

29 Oct 2013

Component of grape, citrus fruits block formation of kidney cysts

A new study published today in British Journal of Pharmacology has identified that a component of grapefruit and other citrus fruits, naringenin, successfully blocks the formation of kidney cysts.

3 Oct 2013

Research uncovers defective process in patients with autosomal dominant polycystic kidney disease

New research has uncovered a process that is defective in patients with autosomal dominant polycystic kidney disease, a common cause of kidney failure. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN), point to a new potential strategy for preventing and treating the disease.

6 Sep 2013

Discovery sheds new light on causes of debilitating diseases and birth defects

Danish researchers have just published findings that explain a previously unknown mechanism used by cells to communicate with one another. The research significantly contributes to understanding why some children are born with malformations and why children and adults may develop life-threatening diseases.

10 Jun 2013

New clinical algorithm to treat complex pediatric patients with ARPKD

A collaborative team of physician-scientists at the Medical College of Wisconsin and Children's Hospital of Wisconsin Research Institute has developed a new evidence-based, clinical algorithm to help physicians treat complex patients with autosomal recessive polycystic kidney disease.

29 Apr 2013

FDA accepts Otsuka Pharmaceutical's tolvaptan NDA for priority review

Otsuka Pharmaceutical Co., Ltd. announced today that the U.S. Food and Drug Administration has accepted for priority review the company's new drug application for the potential use of tolvaptan for the treatment of autosomal dominant polycystic kidney disease.

15 Apr 2013

Rensselaer professor awarded NIH grant to explore cellular function with links to diverse diseases

The interior of every cell within our bodies is crisscrossed with a network of molecular highways upon which nutrients, replacement parts, and other vital materials travel to their appropriate location.

20 Mar 2013

Researchers to develop new diagnostic tools and treatments for people with rare diseases

A multi-million Euro initiative is bringing together researchers from across the world to develop new diagnostic tools and new treatments for people with rare diseases and to connect research data in this area on a global scale.

25 Jan 2013

Tolvaptan improves kidney health in polycystic kidney disease

A vasopressin V2-receptor blocker slows the increase in total kidney volume and decline in kidney function in patients with autosomal dominant polycystic kidney disease, report US researchers.

12 Nov 2012

Study highlights potential treatment that reduces kidney growth

Autosomal-dominant polycystic kidney disease (ADPKD) is one of the most common genetic disorders, affecting one in every 1,000 people and responsible for up to ten percent of patients on dialysis worldwide. The disease is characterized by the development of cysts that lead to progressive kidney failure and necessitate dialysis or a kidney transplant in most patients aged around fifty. Moreover, the persistent cyst growth causes high blood pressure and painful complications.

5 Nov 2012

Tolvaptan shows promise in treating autosomal dominant polycystic kidney disease

A drug therapy shows promise for treating an inherited form of kidney disease called autosomal dominant polycystic kidney disease (ADPKD), Mayo Clinic researchers say.

3 Nov 2012

Gene therapy approach restores ability to smell in mouse model of congenital anosmia

Scientists funded by the National Institutes of Health have restored the ability to smell in a mouse model of a human genetic disorder that causes congenital anosmia-the inability to smell from birth. The approach uses gene therapy to regrow cilia, cell structures that are essential for olfactory function.

3 Sep 2012

Scientists restore sense of smell in mice through gene therapy

Scientists have restored the sense of smell in mice through gene therapy for the first time -- a hopeful sign for people who can't smell anything from birth or lose it due to disease.

3 Sep 2012

Polycystic Kidney Disease News and Research

Latest Polycystic Kidney Disease News and Research

Otsuka obtains regulatory approval in Japan for pharmacological treatment of ADPKD

Scientists discover that natural product in grapefruit can prevent kidney cysts

Researchers discover protein required for growth of hair-like structures on cell surfaces

EMA accepts Otsuka's marketing authorisation application for tolvaptan for treatment of ADPKD

Holiday reads: Squabbling families, the psychology of Santa, holiday stress and chocolate chip cookies

Scientists at Salk Institute develop novel platform to study kidney diseases

Researchers generate three-dimensional kidney structures from human stem cells

3Sbio acquires patents for DJ5 to delay hereditary renal disease in ADPKD patients

Component of grape, citrus fruits block formation of kidney cysts

Research uncovers defective process in patients with autosomal dominant polycystic kidney disease

Discovery sheds new light on causes of debilitating diseases and birth defects

New clinical algorithm to treat complex pediatric patients with ARPKD

FDA accepts Otsuka Pharmaceutical's tolvaptan NDA for priority review

Rensselaer professor awarded NIH grant to explore cellular function with links to diverse diseases

Researchers to develop new diagnostic tools and treatments for people with rare diseases

Tolvaptan improves kidney health in polycystic kidney disease

Study highlights potential treatment that reduces kidney growth

Tolvaptan shows promise in treating autosomal dominant polycystic kidney disease

Gene therapy approach restores ability to smell in mouse model of congenital anosmia

Scientists restore sense of smell in mice through gene therapy

Exploring the intersection of biology and proteomics

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Polycystic Kidney Disease News and Research

Latest Polycystic Kidney Disease News and Research

Exploring the intersection of biology and proteomics

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

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