Prostate Cancer

Prostate cancer is the most common non-skin cancer in the United States and the third most common cancer worldwide. More than 1 million men in the United States have prostate cancer and it is the second leading cause of cancer death amongst men after lung cancer. In 2009, an estimated 192,280 new cases are expected to be diagnosed and approximately 27,360 men are expected to die from the disease. Castration-resistant prostate cancer (CRPC) is defined as prostate cancer that continues to grow despite all standard-of-care hormonal (anti-androgen) therapies. Patients with castration-resistant (also known as hormone-refractory) prostate cancer have few treatment options and a poor prognosis.

Prostate Cancer

Prostate cancer is one of the most common cancers in men, with more than 40,000 new cases diagnosed every year in the UK. This is usually a slow growing cancer and most men do not notice the symptoms until the cancer has become large enough to press against the urethra and interfere with urination.

The Prostate

Prostate Cancer Risk Factors

Prostate Cancer Screening

Prostate Cancer Symptoms

Prostate cancer complications

Prostate Cancer Diagnosis

Prostate Cancer Staging

Prostate Cancer Treatment

Radiation therapy for prostate cancer

Life after prostate cancer treatment

Prostate cancer prevention

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Survival rates of prostate cancer

Precancerous conditions of the prostate

Prostate Cancer Questions

Prostate Cancer Epidemiology

Prostate Cancer Research

Prostate Cancer Partin Tables

Prostate Cancer and Genetics

Prostate Cancer and Diet

Rectal Examination for Prostate Cancer

Cryosurgery for prostate cancer

Hormonal therapy for prostate cancer

Prostate cancer alternative and complementary therapies

Palliative treatment and end of life care for prostate cancer

Vasectomy and prostate cancer: Myth or reality?

The International Prostate Symptoms Score (IPSS)

Types of PSA Test

What is the PSA Test?

Prostate Biopsy

PSA Test in Men Who Have Been Treated for Prostate Cancer

PSA False Positive and False Negative Results

Differentiating between prostate cancer and prostate enlargement

Choosing the best treatment of prostate cancer - by stage

What is the PCA3 Test?

What is the Gleason Score?

What is Prostatectomy?

What is Prostatitis?

Causes of prostatitis

Prostatitis symptoms

Diagnosis of prostatitis

Treatment of prostatitis

What is TURP?

What is medical castration?

What is benign prostatic hyperplasia?

Diagnosis of Benign Prostatic Hyperplasia (BPH)

Symptoms of Benign Prostatic Hyperplasia (BHP)

Causes of benign prostatic hyperplasia

Treatment of Benign Prostatic Hyperplasia (BHP)

Should MRI be Used to Diagnose Prostate Cancer?

Prostate Cancer and Exercise

Prostate Cancer Epidemiology Worldwide

Prostate Cancer Cell Dormancy and Activation

Single Nucleotide Polymorphisms and Prostate Cancer

Gallium Ga 68-labeled PSMA-11 PET/CT Imaging for Prostate Cancer

Can Curcumin Prevent or Treat Prostate Cancer?

Brachytherapy for Prostate Cancer

Latest Prostate Cancer News and Research

Simple process could enhance personalization of cancer therapy

Researchers have developed a simplified process that could enhance personalization of cancer therapy based on a single nuclear medicine scan.

12 Aug 2020

Darolutamide shows indication of considerable added benefit in prostate cancer

Up to now, adult men with non-metastatic castration-resistant prostate cancer (nmCRPC) at high risk of developing metastatic disease usually continued their conventional androgen deprivation therapy (ADT) while the cancer was observed for the occurrence of metastases (so-called watchful waiting).

3 Aug 2020

New method to detect rare circulating tumor cells in blood samples

Metastasis - the development of tumor growth at a secondary site - is responsible for the majority of cancer-related deaths. It occurs when the primary tumor site sheds cancerous cells which are then circulated through the body via blood vessels or lymph nodes.

3 Aug 2020

New blood test can detect prostate cancer and confirm the stage of the disease

A new blood test developed by scientists and clinicians is able to detect the presence of prostate cancer and confirm how advanced it is.

30 Jul 2020

Combination of certain drugs can do more harm than good, shows study

A team of researchers at the Norwegian University of Science and Technology (NTNU) investigating how a certain type of drugs can kill cells has discovered that these drugs can do more harm than good when used in combination with other cancer treatments.

29 Jul 2020

Study shows moderate exercise reduces side effects of prostate cancer treatment

New research published this weekinExperimental Physiologyfound that in prostate cancer survivors,a moderate bout of exercise kept the cell count of certain type of immune cells at a normal level, suggesting the exercise is safe for prostate cancer survivors.

29 Jul 2020

Cancer-related care has decreased since the start of COVID-19

Research from the Sidney Kimmel Cancer Center - Jefferson Health (SKCC) found significant decreases nationwide in the number of patients being seen for cancer-related care as the COVID-19 pandemic progressed during the few first months of 2020.

28 Jul 2020

Exploiting 'synthetic lethality' to identify cancer targets

With advances in genome sequencing, cancer treatments have increasingly sought to leverage the idea of "synthetic lethality," exploiting cancer-specific genetic defects to identify targets that are uniquely essential to the survival of cancer cells.

28 Jul 2020

Researchers find link between healthy diet and lower risk of prostate cancer

The Canadian Cancer Society estimates that more than 23,000 Canadians will be diagnosed with prostate cancer in 2020. Among other risk factors, more and more studies point to diet as a major factor in the development of prostate cancer, as it is for cardiovascular disease, diabetes, and obesity.

27 Jul 2020

New model may explain why certain cancer cells are resistant to therapy

Cancer's knack for developing resistance to chemotherapy has long been a major obstacle to achieving lasting remissions or cures.

24 Jul 2020

Gene signature explains why 18F-FDG imaging performs better for PSMA-suppressed prostate cancer patients

Scientists have uncovered the genomic signature to explain why 18F-FDG imaging performs better than PSMA-targeted imaging for prostate cancer patients with low or no expression of the prostate-specific membrane antigen (PSMA).

23 Jul 2020

Prostate tumors reactivate dormant molecular program during metastatic progression

When prostate cancer progresses to a more-dangerous metastatic state, it does so by resurrecting dormant molecular mechanisms that had guided the fetal development of the prostate gland but had been subsequently switched off, say scientists from Dana-Farber Cancer Institute.

20 Jul 2020

How to decide whether or not to start treatment for prostate cancer?

You have been diagnosed with prostate cancer and your doctor gives you the option of not being treated, but of remaining under observation: is there any objective way you can decide to be treated or not treated? What should you do?

19 Jul 2020

Study provides new insights into genetic susceptibility of COVID-19

A new Cleveland Clinic study has identified genetic factors that may influence susceptibility to COVID-19. Published today in BMC Medicine, the study findings could guide personalized treatment for COVID-19.

15 Jul 2020

New trial investigates if prostate cancer drug can be used to treat COVID-19

In a new trial, Swedish researchers will investigate if a medicine normally used to treat prostate cancer can also be used to treat COVID-19 in patients.

15 Jul 2020

PSMA PET/CT has high impact in the detection, management of recurrent prostate cancer

New research confirms the high impact of PSMA PET/CT in the detection and management of recurrent disease in prostate cancer patients.

13 Jul 2020

New theranostic agents show efficacy for precision diagnosis, treatment of prostate cancer

Researchers have developed a new pair of agents that show exceptional effectiveness for precision diagnosis and treatment of prostate cancer in preclinical studies.

13 Jul 2020

Newly identified gene variants in Black Americans could lead to precision prostate cancer therapies

Black men in the United States are known to suffer disproportionately from prostate cancer, but few studies have investigated whether genetic differences in prostate tumors could have anything to do with these health disparities.

11 Jul 2020

New silicone rubber face mask can be easily sterilized and worn many times

Researchers at MIT and Brigham and Women's Hospital have designed a new face mask that they believe could stop viral particles as effectively as N95 masks.

9 Jul 2020

Brigham experts develop reusable N95 mask alternative

With N95 masks in short supply, a team of bioengineers and clinical experts from Brigham and Women's Hospital and the Massachusetts Institute of Technology has been developing a new, sustainable solution for health care workers to provide protection during the pandemic.

8 Jul 2020