Prostate Cancer

Prostate cancer is the most common non-skin cancer in the United States and the third most common cancer worldwide. More than 1 million men in the United States have prostate cancer and it is the second leading cause of cancer death amongst men after lung cancer. In 2009, an estimated 192,280 new cases are expected to be diagnosed and approximately 27,360 men are expected to die from the disease. Castration-resistant prostate cancer (CRPC) is defined as prostate cancer that continues to grow despite all standard-of-care hormonal (anti-androgen) therapies. Patients with castration-resistant (also known as hormone-refractory) prostate cancer have few treatment options and a poor prognosis.

Prostate Cancer

Prostate cancer is one of the most common cancers in men, with more than 40,000 new cases diagnosed every year in the UK. This is usually a slow growing cancer and most men do not notice the symptoms until the cancer has become large enough to press against the urethra and interfere with urination.

Brachytherapy for Prostate Cancer

The Prostate

Prostatitis symptoms

What is the Gleason Score?

Choosing the best treatment of prostate cancer - by stage

Causes of benign prostatic hyperplasia

Recent Genetic Breakthroughs in Prostate Cancer Research

Can Curcumin Prevent or Treat Prostate Cancer?

What is Prostatectomy?

Single Nucleotide Polymorphisms and Prostate Cancer

Breakthroughs in Prostate Cancer Treatments

See more featured articles »

Radiation therapy for prostate cancer

What is Prostatitis?

Rectal Examination for Prostate Cancer

Gallium Ga 68-labeled PSMA-11 PET/CT Imaging for Prostate Cancer

Prostate cancer complications

Prostate Biopsy

What is benign prostatic hyperplasia?

The International Prostate Symptoms Score (IPSS)

Cryosurgery for prostate cancer

Prostate Cancer Risk Factors

What Should You Avoid Before a PSA Test?

PSA Test in Men Who Have Been Treated for Prostate Cancer

Prostate Cancer Questions

Should MRI be Used to Diagnose Prostate Cancer?

Prostate Cancer Epidemiology Worldwide

Precancerous conditions of the prostate

Hormonal therapy for prostate cancer

Prostate Cancer and Diet

What is the PCA3 Test?

Diagnosis of Benign Prostatic Hyperplasia (BPH)

What is medical castration?

What is TURP?

Prostate Cancer Diagnosis

Palliative treatment and end of life care for prostate cancer

Differentiating between prostate cancer and prostate enlargement

Prostate Cancer Partin Tables

Causes of prostatitis

Types of PSA Test

Life after prostate cancer treatment

Vasectomy and prostate cancer: Myth or reality?

What is the PSA Test?

Symptoms of Benign Prostatic Hyperplasia (BHP)

PSA False Positive and False Negative Results

Treatment of Benign Prostatic Hyperplasia (BHP)

Gold Nanoparticles Use in Prostate Cancer

Prostate Cancer Cell Dormancy and Activation

Prostate Cancer Treatment

Prostate Cancer Screening

Prostate cancer prevention

Treatment of prostatitis

Prostate Cancer and Exercise

Prostate Cancer Research

Survival rates of prostate cancer

Diagnosis of prostatitis

Prostate Cancer Epidemiology

Prostate Cancer Staging

Prostate Cancer and Genetics

Prostate cancer alternative and complementary therapies

Prostate Cancer Symptoms

Latest Prostate Cancer News and Research

Shorter hormone therapy may be enough for many men with prostate cancer

A study co-led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found that most of the benefits of androgen deprivation therapy (ADT) for prostate cancer occur within the first 9 to 12 months.

25 Nov 2025

Genetic signals reveal why erectile dysfunction develops and who is most at risk

This multi-ancestry genomic study identifies key genetic loci underlying erectile dysfunction and shows that ED risk is shaped by both cardiometabolic and substance use–related genetic pathways. Using EHR-linked data, the researchers uncover SIM1-related mechanisms, modest PRS performance, and bidirectional genetic links with obesity, diabetes, and addiction traits.

25 Nov 2025

Landmark prostate cancer screening trial launches in the UK

The first men have been invited to take part in Prostate Cancer UK's TRANSFORM trial, kicking off the biggest prostate cancer screening study in a generation.

22 Nov 2025

Evidence links severe gum disease to erectile dysfunction and broader men’s health risks

A healthy mouth is also key to a healthy body, as gum disease has been linked to non-communicable diseases such as diabetes, cardiovascular disease, rheumatoid arthritis and Alzheimer's.

20 Nov 2025

Study uncovers promising therapeutic strategies against neuroendocrine prostate cancer

A new study has uncovered promising therapeutic strategies against one of the deadliest forms of prostate cancer.

20 Nov 2025

Single-port robotic surgery transforms cancer care at NYU Langone Hospital—Long Island

After enduring seven prior abdominal surgeries, 64-year-old Joy Monetti from Islip was no stranger to painful procedures and lengthy recoveries.

17 Nov 2025

Age impacts systemic therapy outcomes in metastatic prostate cancer

Many things are evaluated when doctors are putting a treatment plan together for prostate cancer patients. A new study says one more factor should be considered – chronological age.

10 Nov 2025

UCLA team receives grant to establish new clinical cancer research center for veterans

Dr. Matthew Rettig and his research team have been awarded a Clinical Cancer Research Center grant from the U.S. Department of Veterans Affairs to establish a new clinical cancer research center that will expand access to precision oncology clinical trials and patient care for veterans across the Southwest United States.

10 Nov 2025

Study identifies thyroid hormone pathway as key player in prostate cancer development

A hormone produced in the thyroid gland can play a key role in the development of prostate cancer.

10 Nov 2025

USC-led study advances understanding of prostate cancer genetics in Black men

New prostate cancer research from an international team led by the Center for Genetic Epidemiology at the Keck School of Medicine of USC has yielded discoveries that could improve screening and treatment for patients of African ancestry.

5 Nov 2025

PTGES3 emerges as key regulator of androgen receptor in prostate cancer

A poorly characterized protein, historically thought to be a chaperone or enzyme, may actually be a key player in prostate cancer.

5 Nov 2025

Do GLP-1 drugs cause cancer? New review says no, may even protect

A comprehensive review in The Journal of Clinical Investigation finds no overall link between GLP-1 receptor agonists and increased cancer risk, countering early safety concerns. Instead, evidence suggests possible protective effects for certain cancers, supported by metabolic and immune-modulating mechanisms.

4 Nov 2025

How walnuts combat inflammation and oxidative stress in the body

This review in Food Science & Nutrition synthesizes evidence showing that walnuts (Juglans regia L.) exert potent antioxidant, anti-inflammatory, apoptosis-regulatory, and immunomodulatory effects through bioactive compounds influencing mitochondrial, cytokine, and redox pathways.

3 Nov 2025

Study confirms PSA screening improves survival and safety

After 23 years of follow-up, the European Randomized Study of Screening for Prostate Cancer (ERSPC) confirmed a 13% lower prostate cancer mortality with PSA testing and an improved harm–benefit ratio over time. Risk-based screening could sustain mortality gains while reducing overdiagnosis and unnecessary treatment.

30 Oct 2025

Breakthrough combo therapy lowers death risk in recurrent prostate cancer

Men whose prostate cancer returns after surgery or radiation therapy may now benefit from a new drug combination shown in clinical trials to cut the risk of death by more than 40%.

23 Oct 2025

Discovery offers a breakthrough approach to combat prostate tumor growth

Prostate cancer relies on genetic "switches", called enhancers, that can turn on tumor-promoting genes.

22 Oct 2025

Study provides a new approach for the treatment of prostate tumors

An international research team led by the Medical University of Vienna has demonstrated for the first time that thyroid hormone plays a key role in the development and progression of prostate cancer.

21 Oct 2025

New imaging technique boosts survival in prostate cancer patients

A multicenter study led by London Health Sciences Centre Research Institute (LHSCRI), Lawson Research Institute of St. Joseph's Health Care London (Lawson), and University Health Network (UHN) has found a novel imaging solution, called prostate-specific membrane antigen (PSMA) positron emission tomography (PET) scanning, can more effectively detect the recurrence of prostate cancer compared to standard imaging methods, and is associated with improved survival outcomes.

14 Oct 2025

Why brittle bones aren’t just a woman’s problem

Ronald Klein was biking around his neighborhood in North Wales, Pennsylvania, in 2006 and tried to jump a curb. "But I was going too slow — I didn't have enough momentum," he recalled.

14 Oct 2025

Blocking two enzymes weakens prostate tumors and boosts drug effectiveness

A major international study has uncovered a new vulnerability in prostate cancer cells that could help improve treatment for one of the most common cancers affecting men.

13 Oct 2025