Schizophrenia News and Research

Latest Schizophrenia News and Research

How memory deals with a change in plans

You're about to leave work at the end of the day when your cell phone rings: it's your spouse, asking that you pick up a gallon of milk on the way home. Before you head out the door, though, your spouse calls again and asks you to stop by the hardware store too. Based on your knowledge of the area and rush-hour traffic, you decide to get the milk first and the toilet plunger second. But whoops! The phone rings again. This time, it's your boss, asking you to work late. That means another change of plans.

25 Aug 2008

New sleep lab to benefit shift-workers

Two specialist laboratories opening night at the University of Sydney will shed light on the impact of sleep and circadian disruption in medical disorders and shift-workers, and the neurobiological mechanisms underlying substance abuse and depression.

21 Aug 2008

Molecular switch provides insights into a form of altered brain activity occurring in schizophrenia

People with schizophrenia have an alteration in a pattern of brain electrical activity associated with learning and memory. Now, researchers from the National Institutes of Health and Sweden's Karolinska Institute have identified in mouse brain tissue a molecular switch that, when thrown, increases the strength of this electrical pattern. The researchers found that adding the brain chemical Neuregulin-1 to the brain tissue boosted the electrical signals that the tissue generated.

13 Aug 2008

Dopamine and Parkinson's

Parkinson's disease and drug addiction are polar opposite diseases, but both depend upon dopamine in the brain. Parkinson's patients don't have enough of it; drug addicts get too much of it. Although the importance of dopamine in these disorders has been well known, the way it works has been a mystery.

10 Aug 2008

Oestrogen - a beneficial addition to treatment of schizophrenia in women

Australian scientists have found that women suffering from schizophrenia were less likely to suffer hallucinations or delusions, when the hormone oestrogen was added to their treatment.

4 Aug 2008

Human brains pay a price for being big

Metabolic changes responsible for the evolution of our unique cognitive abilities indicate that the brain may have been pushed to the limit of its capabilities. Research published today in BioMed Central's open access journal Genome Biology adds weight to the theory that schizophrenia is a costly by-product of human brain evolution.

4 Aug 2008

Researchers examine link between prenatal vitamin D levels and schizophrenia

Researchers from UQ's Queensland Brain Institute are set to conduct a world-first trial into the link between prenatal vitamin D levels and schizophrenia prevalence.

3 Aug 2008

Improving the prognosis for schizophrenic disorders

Throughout the world, scientists are attempting to recognize and treat schizophrenic disorders at an earlier stage. It is hoped that this will improve the prognosis, which has often been unfavorable.

31 Jul 2008

Unusual chromosomal changes increase the risk of schizophrenia

People with schizophrenia have an increased number of unusual chromosomal changes, particularly structural changes that have the potential to alter the function of the genes. These results were published today in the scientific journal Nature.

31 Jul 2008

Genetic clues to schizophrenia uncovered

New research has found genetic flaws which scientists say are about 15 percent more frequent in people with schizophrenia.

30 Jul 2008

How anti-depressants and cocaine interact with brain

In a first, scientists from Weill Cornell Medical College and Columbia University Medical Center have described the specifics of how brain cells process antidepressant drugs, cocaine and amphetamines. These novel findings could prove useful in the development of more targeted medication therapies for a host of psychiatric diseases, most notably in the area of addiction.

28 Jul 2008

Study shows promising results in deep brain stimulation for treatment-resistant depression

New data from a study of patients with treatment-resistant depression who underwent deep brain stimulation (DBS) in the subcallosal cingulate region (SCG or Cg25) of the brain shows that this intervention is generally safe and provides significant improvement in patients as early as one month after treatment. The patients also experienced continued and sustained improvement over time.

21 Jul 2008

Using genetics to improve traditional psychiatric diagnoses

Psychiatry has begun the laborious effort of preparing the DSM-V, the new iteration of its diagnostic manual. In so doing, it once again wrestles with the task set by Carl Linnaeus, to "cleave nature at its joints." However, these "joints," the boundaries between psychiatric disorders, such as that between bipolar disorder and schizophrenia, are far from clear. Prior versions of DSM followed the path outlined by Emil Kraeplin in separating these disorders into distinct categories. Yet, we now know that symptoms of bipolar disorder may be seen in patients with schizophrenia and the reverse is true, as well.

17 Jul 2008

Shared gene expression alterations in schizophrenia and bipolar disorder

Both schizophrenia and bipolar disorder can be disabling conditions, and both present clinically with significant mood and psychotic symptoms. These two illnesses also share genetic variants that might be involved in the predisposition to both disorders.

17 Jul 2008

Incorrectly cleaved protein leads to schizophrenia

Schizophrenia is a disease that strikes an average of 4,000 Belgians every year. The causes of this psychiatric disorder are not yet clear.

14 Jul 2008

Stem cells help keep the brain healthy and active

For some years, scientists have been speculating over why stem cells exist in the brain, as brain regeneration is limited. A German team of neuroscientists believe these stem cells help keep the brain healthy and active.

13 Jul 2008

An analysis of food's affect on the brain

In addition to helping protect us from heart disease and cancer, a balanced diet and regular exercise can also protect the brain and ward off mental disorders.

9 Jul 2008

The good and bad side of dopamine

The chemical dopamine induces both desire and dread, according to new animal research in the July 9 issue of The Journal of Neuroscience. Although dopamine is well known to motivate animals and people to seek positive rewards, the study indicates that it also can promote negative feelings like fear.

9 Jul 2008

Genetic change in dopamine transporter supports a role for dopamine signaling in ADHD

A genetic change in the dopamine transporter - one of the brain's dopamine-handling proteins - makes it behave as if amphetamine is present and "run backward," Vanderbilt University Medical Center investigators report this week in The Journal of Neuroscience.

9 Jul 2008

Protein found in immune cells may be a reliable marker for schizophrenia risk

Schizophrenia is a severe and complex psychiatric illness that affects about 1% of the population. Diagnosis currently relies on subjective clinical interviews and the assessment of ambiguous symptoms, which frequently leads to delayed diagnosis and treatment. As such, biomarkers that would indicate schizophrenia risk or onset would be extremely useful.

8 Jul 2008