Seizure News and Research

Latest Seizure News and Research

Fetal exposure to valproate impairs IQ till age six

Researchers in the U.S. and U.K. are conducting an ongoing investigation of the cognitive effect of fetal exposure across four commonly used antiepileptic drugs (AEDs) as part of an NIH-funded Neurodevelopmental Effects of Antiepileptic Drugs (NEAD) Study. An early NEAD analysis found that fetal exposure to valproate impairs IQ at age three.

6 Dec 2011

Converting patients to lamotrigine extended-release for epilepsy treatment found effective and safe

Epilepsy drug-switching study shows that using more ethical control groups could be the way forward for testing both drug efficacy and safety

5 Dec 2011

Scientists discover new candidate gene for Dravet syndrome

Dravet syndrome is a severe genetic epilepsy that appears early in life. About 75 percent of cases can be attributed to mutations in the SCN1A gene encoding the sodium channel NaV1.1. The remaining patients with this syndrome are without a definitive molecular genetic diagnosis. Research presented today at the American Epilepsy Society's 65th Annual Meeting has found a non-SCN1A candidate gene and suggests that Dravet syndrome may be caused by any one of a number of yet unidentified genes.

5 Dec 2011

Epilepsy patients can benefit from gamma knife radiosurgery

Neurosurgeons continue to explore minimally invasive surgery with gamma radiation (gamma knife surgery / GKS) in the treatment of brain lesions causing seizures and epilepsy. Studies of the procedure are showing it to be an effective alternative to invasive microsurgery for hypothalamic hamartomas and other lesions that lie deep within the brain.

5 Dec 2011

Study: 3D-TV may cause seizures in children and adolescents

Certain visual patterns and flashing images can provoke seizures in susceptible individuals, particularly among children and adolescents. Some media reports on the recent introduction of 3D-television sets suggest that this new technology may cause seizures in some viewers.

5 Dec 2011

Potential medical and social barriers to resective epilepsy surgery in patients after initial evaluation

Epilepsy surgery is safe, effective and often curative in selected candidates. Although candidates for epilepsy surgery in the United States are estimated between 100,000 and 200,000, fewer than 5,000 such surgeries are conducted each year. The cause of this disparity is multi-factorial, including an unexplained low level of referrals by physicians and choices made by patients themselves.

5 Dec 2011

Hypothalamus may be involved in generating laughter

Anecdotal evidence suggests that the hypothalamus, a structure lying deep within the brain may be involved in generating laughter. Gelastic epilepsy, a rare condition characterized by laughing seizures, is commonly the result of a congenital brain lesion within the hypothalamus.

5 Dec 2011

U-M scientists generate Dravet-derived neurons

Scientists investigating the fundamental cause of Dravet syndrome, a severe childhood epilepsy, have reprogrammed fibroblasts, a type of skin cell, from Dravet patients and generated patient-specific neurons.

5 Dec 2011

Bromide shows promise against SCN1A-associated Dravet syndrome with intractable seizures

In the mid-nineteenth century Charles Locock, physician to Queen Victoria, introduced bromide as the first effective treatment for epilepsy. The drug was little used in treating the disorder until 1868, however, when its efficacy against seizures was first demonstrated in a clinical trial. Bromide was the sole anticonvulsant available until 1912 and the introduction of phenobarbital.

5 Dec 2011

Post-baseline vision data from Lundbeck's Sabril patient registry presented at AES meeting

Post-baseline vision data from Lundbeck's Sabril patient registry is available for the first time today as a late-breaking poster presentation at the annual meeting of the American Epilepsy Society.

5 Dec 2011

Two-thirds of women with catamenial epilepsy have diagnosis of partial epilepsy, study finds

In women of childbearing age with epilepsy, seizure exacerbation may occur either at the time of menstruation or ovulation. Investigators in a specialized epilepsy center have analyzed the data on a group of patients with seizures associated with their menstrual cycles (catamenial seizures) for type of epilepsy, seizure frequency, response to medication, neuroimaging findings, and seizures during pregnancy.

3 Dec 2011

Progesterone can benefit women with catamenial seizures: Study

Seizures in women of childbearing age commonly show patterns of exacerbation that involve hormones as a factor. Investigators today reported the favorable outcome of a multicenter randomized, double-blinded, placebo-controlled phase III clinical trial of progesterone therapy in reducing these perimenstrually exacerbated (catamenial) seizures.

3 Dec 2011

Al-Shabab bans U.N., other aid agencies from working in Somalia; U.N. SG condemns actions

"Al-Shabab rebels banned some U.N. and international aid agencies from working in Somalia on Monday and began seizing and looting some of their offices in southern and central areas of the country, the Islamist group and aid sources said," Reuters reports.

30 Nov 2011

Seizure drug slows spread of uveal melanoma

A drug commonly used to treat seizures appears to make eye tumors less likely to grow if they spread to other parts of the body, according to researchers at Washington University School of Medicine in St. Louis.

29 Nov 2011

FDA takes legal action against dietary supplement manufacturer in Pennsylvania

The FDA today took legal action against a dietary supplement maker and owner for substituting ingredients and products without noting the changes on the final product labels. The permanent injunction, filed on behalf of the FDA by the U.S. Department of Justice, would stop the defendants from making and distributing more than 400 products for being in violation of the Federal Food, Drug, and Cosmetic Act.

24 Nov 2011

Abnormal levels of caffeine in water indicate human contamination

Researchers led by Prof. S-bastien Sauv- of the University of Montreal's Department of Chemistry have discovered that traces of caffeine are a useful indicator of the contamination of our water by sewers.

23 Nov 2011

FDA Commissioner revokes approval of Genentech's Avastin for treatment of mBC

Genentech, a member of the Roche Group, announced today that the FDA Commissioner is revoking the approval of Avastin (bevacizumab) for the treatment of mBC in the United States.

18 Nov 2011

Penn-led team develops microelectronic device to map brain activity

A team of researchers co-led by the University of Pennsylvania has developed and tested a new high-resolution, ultra-thin device capable of recording brain activity from the cortical surface without having to use penetrating electrodes.

14 Nov 2011

Flexible brain implant could treat epileptic seizures

Researchers funded by the National Institutes of Health have developed a flexible brain implant that could one day be used to treat epileptic seizures. In animal studies, the researchers used the device - a type of electrode array that conforms to the brain's surface - to take an unprecedented look at the brain activity underlying seizures.

14 Nov 2011

NYU Langone professor offers guidance on risk factors, interventions for SUDEP

Over time, epileptic seizures can lead to major health issues, including significant cognitive decline and even death, warns Orrin Devinsky, MD, professor, Departments of Neurology, Neurosurgery and Psychiatry at NYU Langone Medical Center.

11 Nov 2011

Seizure News and Research

Latest Seizure News and Research

Fetal exposure to valproate impairs IQ till age six

Converting patients to lamotrigine extended-release for epilepsy treatment found effective and safe

Scientists discover new candidate gene for Dravet syndrome

Epilepsy patients can benefit from gamma knife radiosurgery

Study: 3D-TV may cause seizures in children and adolescents

Potential medical and social barriers to resective epilepsy surgery in patients after initial evaluation

Hypothalamus may be involved in generating laughter

U-M scientists generate Dravet-derived neurons

Bromide shows promise against SCN1A-associated Dravet syndrome with intractable seizures

Post-baseline vision data from Lundbeck's Sabril patient registry presented at AES meeting

Two-thirds of women with catamenial epilepsy have diagnosis of partial epilepsy, study finds

Progesterone can benefit women with catamenial seizures: Study

Al-Shabab bans U.N., other aid agencies from working in Somalia; U.N. SG condemns actions

Seizure drug slows spread of uveal melanoma

FDA takes legal action against dietary supplement manufacturer in Pennsylvania

Abnormal levels of caffeine in water indicate human contamination

FDA Commissioner revokes approval of Genentech's Avastin for treatment of mBC

Penn-led team develops microelectronic device to map brain activity

Flexible brain implant could treat epileptic seizures

NYU Langone professor offers guidance on risk factors, interventions for SUDEP

Everything you need to know about epilepsy eBook

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

Seizure News and Research

Latest Seizure News and Research

Everything you need to know about epilepsy eBook

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

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