Seizure

An epileptic seizure, occasionally referred to as a fit, is defined as a transient symptom of "abnormal excessive or synchronous neuronal activity in the brain".

What is a Seizure?

Seizures are caused by abnormal electrical activity in the brain. In the healthy brain, electrical and chemical signals are fired between nerves called neurons to drive the brain's ability to think, feel and send instructions to parts of the body, such as the muscles. Seizures occur when this electrical system in the brain malfunctions.

Epileptic Seizure Management

Epileptic Seizure Symptoms

Epileptic Seizure Diagnosis

Epileptic Seizure Causes

Latest Seizure News and Research

Early diagnosis and treatment help teenager overcome rare epilepsy

Christopher Sepúlveda was just 2 years old when his parents noticed something was wrong. Christopher began experiencing involuntary movements of his mouth and eyes, and episodes when he would freeze and not move for nearly two minutes- something their pediatrician at the time said could be a tic disorder.

6 Nov 2026

Targeting brain protein may help treat MEF2C-related neurological disorders

A particular signaling protein in the brain could be a therapeutic target for neurological disorders arising from the deletion of the autism-linked gene MEF2C, University of Illinois Urbana-Champaign researchers found in a new mouse study.

4 Nov 2026

Mount Sinai receives NIH grant to study advanced MRI methods for locating seizures

Researchers at the Icahn School of Medicine at Mount Sinai have received more than $3 million from the National Institutes of Health (NIH) for a five-year study of advanced magnetic resonance imaging (MRI) methods that may help locate seizure-causing brain regions in people with drug-resistant epilepsy.

2 Nov 2026

Ketones may change sleep patterns, but not always for the better

Researchers reviewed animal and human studies and found that ketone bodies may affect sleep stages through energy metabolism and cellular signaling, with the clearest direct evidence involving acetoacetate in mice. They reported mixed human findings and called for controlled studies to separate ketone-specific effects from changes linked to diet, disease, circadian timing, and physiological stress.

28 Oct 2026

Review highlights essential neurological considerations for gender dysphoria care

Gender dysphoria involves distress caused by a mismatch between a person's gender identity and sex assigned at birth.

28 Oct 2026

LINAC-based radiosurgery effectively reduces seizures but causes significant side effects

Drug-resistant epilepsy types, such as mesial temporal lobe epilepsy (MTLE), are surgically managed through anterior temporal lobectomy (ATL).

27 Oct 2026

Accelerated TMS cuts depression treatment time from six weeks to three

Transcranial magnetic stimulation (TMS) has proved to be a very effective non-invasive treatment for people with severe depression who have not had success with medication. But traditional TMS has one significant drawback: time.

21 Oct 2026

Study links abnormal immature astroglia to lower fluid intelligence in older epilepsy patients

A new USC-led study links abnormal immature astroglia, star-shaped cells that support brain function, to lower fluid intelligence, or the ability to solve new problems, in older adults with epilepsy.

20 Oct 2026

Hybrid AI architecture improves seizure prediction using EEG signals

Epilepsy affects about 50 million people worldwide and can seriously affect patients' quality of life. Electroencephalography (EEG), which records the brain's electrical activity in real time, plays an important role in epilepsy diagnosis and monitoring.

13 Oct 2026

AI helps neurologists distinguish epilepsy from functional seizures

Researchers developed EpiScreen, an AI system that distinguished epilepsy from psychogenic non-epileptic seizures using clinical notes from 13,633 patient records across two institutions. AI assistance improved neurologists’ classification accuracy in a retrospective assessment of 300 cases, but prospective studies must establish its performance and benefits in routine clinical care.

12 Oct 2026

Study finds both the liver and brain drive distinct symptoms of rare genetic epilepsy

A recent study from Johns Hopkins Medicine reveals that both the liver and brain contribute pathways to differing symptoms of the same rare inherited disorder.

9 Oct 2026

Declining benzodiazepine use reflects more cautious medical prescribing practices

The number of benzodiazepine prescriptions like Xanax and Valium dispensed in the United States decreased over the past 10 years, potentially suggesting that doctors have become more cautious when prescribing these sedatives, according to Rutgers Health researchers.

30 Sep 2026

Genomics and AI identify a candidate gene behind rare neurodevelopmental disorder

Researchers at Baylor College of Medicine, the Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital, the Texome Project and collaborating institutions have identified variants in gene BRSK1 as a likely diagnosis for individuals with a rare and complex neurodevelopmental disorder who until now had not received an explanation for their condition.

28 Sep 2026

Brain organoids reveal new clues for childhood epilepsy treatments

Tiny, year-old human brain organoids that mimic the brain of a newborn are providing new clues to potential treatments for a leading genetic cause of childhood epilepsy that typically manifests as the brain matures shortly after birth.

23 Sep 2026

Sex-specific biological clocks reveal how aging differs across the body in women and men

Researchers developed 38 sex-specific biological aging clocks across 15 organ systems, finding differences between females and males in genetic architecture, molecular signatures, disease associations, and mortality patterns. Brain aging clocks were linked to progression from mild cognitive impairment to Alzheimer’s disease in both sexes and to sex-dependent cognitive trajectories among solanezumab-treated A4 participants, while the authors stressed that sex-pooled and sex-interaction models remain complementary approaches.

17 Sep 2026

Existing anti-seizure drug slows the growth of diffuse midline gliomas

An existing anti-seizure drug slows the growth of a devastating group of childhood cancers, new Stanford Medicine-led research has shown.

17 Sep 2026

Military blast exposure associated with long-term health conditions

Exposure to high-level blasts from incoming explosive devices or land mines among military veterans is associated with an increased risk of several conditions such as seizures, neuropathy and stroke years later, according to a study published September 16, 2026, in Neurology, the medical journal of the American Academy of Neurology.

16 Sep 2026

EpilepsyGTx and Viralgen collaborate to advance AAV gene therapy program for epilepsy ahead of first-in-human trial

EpilepsyGTx, a biotechnology company developing gene therapies for refractory epilepsy, and Viralgen, a leading contract development and manufacturing organization (CDMO) specializing in recombinant adeno-associated virus (AAV) gene therapies, today announced a partnership to support production of EpilepsyGTx's lead investigational gene therapy program targeting patients with focal refractory epilepsy (FRE), EPY201, ahead of first-in-human clinical trials.

From EpilepsyGTx 9 Sep 2026

Younger and older brains respond differently to traumatic injury

Conventional wisdom holds that younger brains are better equipped to recover from injury. Their greater flexibility allows them to adapt, rebuild connections and compensate for damage in ways older brains often cannot.

4 Sep 2026

Genetic marker links popular seizure drug to life-threatening reaction

A genetic marker already used to flag risk of a life-threatening reaction to the antibiotic vancomycin also identifies patients at risk of that reaction to lamotrigine - and it is missing from the gene panels clinicians order before prescribing the drug, Vanderbilt Health-led researchers report Sept. 2 in JAMA Network Open.

2 Sep 2026

Seizure

Overview

Epileptic Seizure Management

Epileptic Seizure Symptoms

Epileptic Seizure Diagnosis

Feature Articles

Epileptic Seizure Causes

Latest Seizure News and Research

Early diagnosis and treatment help teenager overcome rare epilepsy

Targeting brain protein may help treat MEF2C-related neurological disorders

Mount Sinai receives NIH grant to study advanced MRI methods for locating seizures

Ketones may change sleep patterns, but not always for the better

Review highlights essential neurological considerations for gender dysphoria care

LINAC-based radiosurgery effectively reduces seizures but causes significant side effects

Accelerated TMS cuts depression treatment time from six weeks to three

Study links abnormal immature astroglia to lower fluid intelligence in older epilepsy patients

Hybrid AI architecture improves seizure prediction using EEG signals

AI helps neurologists distinguish epilepsy from functional seizures

Study finds both the liver and brain drive distinct symptoms of rare genetic epilepsy

Declining benzodiazepine use reflects more cautious medical prescribing practices

Genomics and AI identify a candidate gene behind rare neurodevelopmental disorder

Brain organoids reveal new clues for childhood epilepsy treatments

Sex-specific biological clocks reveal how aging differs across the body in women and men

Existing anti-seizure drug slows the growth of diffuse midline gliomas

Military blast exposure associated with long-term health conditions

EpilepsyGTx and Viralgen collaborate to advance AAV gene therapy program for epilepsy ahead of first-in-human trial

Younger and older brains respond differently to traumatic injury

Genetic marker links popular seizure drug to life-threatening reaction

Everything you need to know about epilepsy eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

Seizure

Overview

Feature Articles

Epileptic Seizure Causes

Latest Seizure News and Research

Everything you need to know about epilepsy eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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