Sepsis News and Research

Latest Sepsis News and Research

New understanding of vagus nerve's role in regulating inflammation

It used to be dogma that the brain was shut away from the actions of the immune system, shielded from the outside forces of nature.

24 Oct 2007

Sanofi Pasteur receives FDA approval of Menactra meningococcal vaccine for children

Sanofi Pasteur, the vaccines division of sanofi-aventis Group, announced today that the U.S. Food and Drug Administration (FDA) has granted licensure to expand the indication for its meningococcal conjugate vaccine, Menactra (Meningococcal [Groups A, C, Y and W-135] Polysaccharide Diphtheria Toxoid Conjugate Vaccine), to include children 2 years through 10 years of age.

22 Oct 2007

Study looks at sepsis and purpura in children

While survival rates for sepsis have increased over the past two decades, children under four and those in adolescence remain highly susceptible to the condition.

18 Oct 2007

Oral antibiotics effective to treat severe urinary tract infections

Although doctors routinely use IV antibiotics to cure patients with severe urinary tract infections (UTI), a new review from suggests that oral antibiotics work just as well - from treating acute symptoms to preventing long-term complications of UTI.

17 Oct 2007

Mortality rates 71 percent lower at top-rated hospitals

Patients have on average a 71 percent lower chance of dying at the nation's top-rated hospitals compared with the lowest-rated hospitals across 18 procedures and conditions analyzed in the tenth annual HealthGrades Hospital Quality in America Study, issued today by HealthGrades, the healthcare ratings company.

16 Oct 2007

Cause and clinical outcome of portal vein thrombosis

Among the 118 patients with portal vein thrombosis, noncirrhotic and nontumoral extrahepatic portal vein obstruction are young and present with well tolerated bleed.

15 Oct 2007

First high-res 3D structures of first mammalian GRP94 protein solved

Dr. Dan Gewirth, Hauptman-Woodward senior research scientist, has just solved the structure of the first mammalian GRP94 protein implicated in immune diseases such as sepsis, AIDS and certain cancers.

15 Oct 2007

Over 60's do well after liver transplantation

Patients who undergo liver transplantation at age 60 or above have 1-year and 5-year survival rates similar to those of younger patients and they experience fewer episodes of rejection.

3 Oct 2007

Potential new therapy for uveitis

An inflammatory eye condition that is one of the world's leading causes of blindness could be treated much more effectively and easily thanks to a new discovery here.

29 Sep 2007

Acute lung injury patients one-third less likely to die in 'closed' model ICUs

Patients with acute lung injury (ALI) are nearly one-third less likely to die if they are treated at ICUs that require board-certified critical care physicians to oversee patient care, as compared to patients treated at ICUs that allow any attending physician to oversee admission and case management.

29 Sep 2007

Care by a hospital-based general physician strongly associated with shorter length of hospital stay in patients

Patients at an academic medical center who are cared for by a hospital-based general physician may have a shorter length of hospital stay than those who are not, especially if the patients require close monitoring or complex discharge planning, according to a report in the September 24 issue of Archives of Internal Medicine.

25 Sep 2007

HSP 90 inhibitors may help ICU patients beat infections

HSP 90 inhibitors, which are finding favor in fighting cancer, may also help battle overwhelming infection in intensive care patients, researchers say.

28 Aug 2007

Study looks at large burns

Large burns can trigger cardiac problems and enhanced inflammatory and hypermetabolic responses in patients, a study in the online open access journal Critical Care suggests.

24 Aug 2007

Surgical options for severe intra-abdominal inflammation

Performing a repeat surgery for patients with peritonitis (severe intra-abdominal inflammation or infection) only when clinical improvement is lacking may have some advantages compared with having the repeat procedure routinely scheduled after the operation, according to a study in the August 22/29 issue of JAMA.

22 Aug 2007

Researchers discover how a protein modulates the inflammatory response in acute respiratory distress syndrome

Researchers at the University of Illinois at Chicago College of Medicine have discovered how a protein modulates the inflammatory response in sudden, life-threatening lung failure.

17 Aug 2007

Researchers discover how Bcl-3 protein stops inflammation

Researchers at the University of Pennsylvania School of Medicine recently identified how a regulatory protein called Bcl-3 helps to control the body's inflammation response to infection by interfering a critical biochemical process called ubiquitination.

12 Aug 2007