Sepsis

Sepsis is a life-threatening illness. Your body's response to a bacterial infection usually causes it. Your immune system goes into overdrive, overwhelming normal processes in your blood. The result is that small blood clots form, blocking blood flow to vital organs. This can lead to organ failure. Babies, old people and those with weakened immune systems are most likely to get sepsis. But even healthy people can become deathly ill from it.

Everything You Need To Know About Sepsis

Sepsis is a life-threatening systemic response to an infection. This article provides an overview of sepsis, including stages, diagnosis and treatment.

Sepsis Prevention

Causes and Symptoms of Sepsis in Newborns

Sepsis and Influenza

Lactate Levels and Sepsis

Acute Respiratory Distress Syndrome (ARDS) and Sepsis

The Development of a Sepsis Scoring System in a Murine Model

Sepsis Complications and Prevention

Sepsis: Identifying the Signs and Administering First Aid

Sepsis Pathophysiology

Sepsis and Pregnancy

Sepsis Epidemiology

See more featured articles »

Sepsis History

How Antimicrobial Resistance Amplifies the Burden of Sepsis

Recovering from Sepsis

Sepsis Diagnosis

Diagnosis and Treatment of Sepsis in Newborns

The Stages of Sepsis

Sepsis at the Molecular Level

Latest Sepsis News and Research

Judge in nursing home bankruptcy case gives families fresh hope of compensation for injuries, deaths

A bankruptcy judge blocked an attempt by a nursing home chain's primary investor to shield himself from settlement payments and liability in lawsuits alleging hundreds of patient injuries and deaths, encouraging those pursuing millions in damages.

19 Dec 2025

Researchers develop AI-powered method for faster lung infection diagnosis

Lung infections like pneumonia are among the world's top killers - but diagnosing them is notoriously hard.

16 Dec 2025

GDF3 protein sustains harmful inflammation in aging immune cells

As people age, their bodies develop a dysfunctional immune system, which can leave older adults more susceptible to conditions like sepsis.

15 Dec 2025

Novel diagnostic approach enables detection of antibiotic resistance and pathogenicity in Klebsiella strains

Antibiotic resistance is one of the most pressing—and quietly advancing—challenges facing modern medicine. Among the most dangerous bacterial pathogens driving this crisis is Klebsiella pneumoniae, a microorganism capable of causing severe infections while evading both antibiotics and the human immune system.

15 Dec 2025

How delays and bankruptcy let a nursing home chain avoid paying settlements for injuries and deaths

Nancy Hunt arrived at an emergency room from a Genesis HealthCare nursing home in Pennsylvania in such dreadful shape, including maggots infesting her gangrened foot, that the hospital called an elder abuse hotline and then the police, her son alleged in a lawsuit.

9 Dec 2025

High BMI and poor physical fitness in adolescence linked to severe bacterial infections in adulthood

High BMI and poor physical fitness during later adolescence increase the risk of both contracting and dying from sepsis and other severe bacterial infections in adulthood, according to a study from the University of Gothenburg.

9 Dec 2025

Targeted approach of immunotherapy improves sepsis outcomes

Immunotherapy for sepsis is effective when doctors tailor the treatment precisely to the patient's immune system condition.

8 Dec 2025

Researchers discover a surprising ally in the fight against insulin resistance and type 2 diabetes

An international research team led by Professor Marc-Emmanuel Dumas at Imperial College London & CNRS together with Prof. Patrice Cani (Imperial & University of Louvain, UCLouvain), Dr. Dominique Gauguier (Imperial & INSERM, Paris) and Prof. Peter Liu (University of Ottawa Heart Institute) has uncovered a surprising ally in the fight against insulin resistance and type 2 diabetes: a microbial metabolite called trimethylamine (TMA).

8 Dec 2025

Microbial warning signs that predict death risk in severe pneumonia

Researchers examine the gut and lung microbiota of severe community-acquired pneumonia patients.

3 Dec 2025

RFK Jr. wants to delay the hepatitis B vaccine. Here’s what parents need to know.

Working out of a tribal-owned hospital in Anchorage, Alaska, liver specialist Brian McMahon has spent decades treating the long shadow of hepatitis B. Before a vaccine became available in the 1980s, he saw the virus claim young lives in western Alaskan communities with stunning speed.

2 Dec 2025

New study links inherited mitochondrial DNA mutation to disrupted immune balance

Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death.

26 Nov 2025

Infection-related hospital stays linked to higher risk of developing dementia

A new research paper was published in Volume 17, Issue 10 of Aging-US on October 13, 2025, titled "Hospitalization with infections and risk of Dementia: a systematic review and meta-analysis."

25 Nov 2025

Lung to gut movement of hospital-acquired bacterium raises the risk of sepsis

A hospital-acquired bacterium that causes serious infections can move from the lungs to the gut inside the same patient, raising the risk of life-threatening sepsis, new research reveals.

25 Nov 2025

Simple hospital program reduces severe maternal infections by 32%

The APT-Sepsis program significantly reduced infection-related outcomes in maternal care, demonstrating the impact of coordinated interventions in hospitals.

24 Nov 2025

C-reactive protein shows stronger accuracy for early-onset sepsis in preterm newborns

Neonatal EOS, a severe bloodstream infection that strikes within the first three days of life, is a major cause of infant illness and death worldwide.

20 Nov 2025

Structured infection prevention program can save mothers’ lives in low-resource settings

A landmark multi-country clinical trial has shown that a structured, sustainable approach to infection prevention and treatment can save women's lives, cutting severe maternal infections and deaths by about one-third (32%) compared to usual care.

19 Nov 2025

Researchers develop new method to combat antibiotic-resistant bacteria using bacteriophages

Antibiotic resistance is one of the most pressing challenges to global public health as harmful microbes evolve to evade these medications.

19 Nov 2025

Study uncovers how tumors exploit a molecular signal to exhaust T cells

A new study has discovered a molecular signal that tumors exploit to exhaust the T cells meant to destroy them-and how silencing that signal could revive the body's immunity.

17 Nov 2025

Scientists invent new method for manufacturing platelet-producing cells from stem cells

Platelets are small, disc-shaped cell fragments in the blood that are essential to stop bleeding and to initiate blood clotting after injury.

13 Nov 2025

Potential breakthrough in treating acute kidney injury with ceramide-targeting drugs

Serious damage to short-term kidney function-known as acute kidney injury, or AKI-can be fatal and also increase the risk of irreversible chronic kidney disease. It can be triggered by stressors ranging from sepsis to heart surgery, and it affects more than half of ICU patients.

12 Nov 2025