Sepsis

Sepsis is a life-threatening illness. Your body's response to a bacterial infection usually causes it. Your immune system goes into overdrive, overwhelming normal processes in your blood. The result is that small blood clots form, blocking blood flow to vital organs. This can lead to organ failure. Babies, old people and those with weakened immune systems are most likely to get sepsis. But even healthy people can become deathly ill from it.

Everything You Need To Know About Sepsis

Sepsis is a life-threatening systemic response to an infection. This article provides an overview of sepsis, including stages, diagnosis and treatment.

Sepsis: Identifying the Signs and Administering First Aid

Sepsis Complications and Prevention

Lactate Levels and Sepsis

How Antimicrobial Resistance Amplifies the Burden of Sepsis

Recovering from Sepsis

Diagnosis and Treatment of Sepsis in Newborns

Sepsis Pathophysiology

Sepsis History

Acute Respiratory Distress Syndrome (ARDS) and Sepsis

Sepsis at the Molecular Level

Causes and Symptoms of Sepsis in Newborns

See more featured articles »

Sepsis Epidemiology

Sepsis Prevention

Sepsis and Influenza

Sepsis Diagnosis

Sepsis and Pregnancy

The Development of a Sepsis Scoring System in a Murine Model

The Stages of Sepsis

Latest Sepsis News and Research

New urine test shows which UTI antibiotic works in under six hours

Researchers have developed a rapid direct-from-urine test that identifies which first-line antibiotic is likely to work for a urinary tract infection in an average of 5.85 hours, instead of the usual two to three days. In studies of 352 routine urine samples and 90 duplicate preservative-tested samples, the method showed high agreement with standard testing, suggesting it could speed treatment and support efforts to curb antimicrobial resistance.

30 Mar 2026

Inside the high-stakes corporate fight over feeding preterm babies

In 2013, a scientist at Abbott Laboratories saw study results with potentially big implications for the company's profits and the lives of some of the world's most fragile people: preterm infants.

30 Mar 2026

New AI system maps gene expression across the whole body

Understanding gene expression within the body has been a boon for 21st century biology and therapeutics, but most discoveries that use these technologies only focus on one organ or one small area of tissue.

27 Mar 2026

Machine learning model can predict 28-day mortality in sepsis patients

Sepsis is one of the most common and lethal syndromes encountered in intensive care units (ICUs), and acute respiratory failure (ARF) represents one of its most critical complications.

27 Mar 2026

Chlorhexidine reduces umbilical cord infections in newborns

A new Cochrane review finds that chlorhexidine likely cuts umbilical cord infection rates by about 29% in low- and middle-income countries, and may reduce newborn deaths.

25 Mar 2026

Inefficient referral pathways delay lifesaving care for millions of injured people

Many seriously injured patients in Global South countries are failing to reach medical care within the lifesaving 'golden hour' and ambulances are often associated with these delays.

23 Mar 2026

Digital decision support tool improves outcomes in colorectal surgery

Research published in The Lancet Gastroenterology & Hepatology provides robust evidence for the use of a digital visualization and decision support tool in colorectal (bowel) surgery.

23 Mar 2026

Pediatric sepsis contributes to significant hospital deaths in the United States

Nearly 1 in 5 pediatric hospital deaths in the United States involve sepsis, according to a new national study published March 22 in JAMA.

23 Mar 2026

New report provides the most detailed picture of preventable child deaths worldwide

An estimated 4.9 million children died before their fifth birthday in 2024, including 2.3 million newborns, according to new estimates released today.

18 Mar 2026

Protein targeted by cancer drugs may help the body fight influenza

A protein already targeted by FDA-approved cancer drugs may also help the body fight influenza, according to new research from The Jackson Laboratory (JAX).

18 Mar 2026

Study identifies risk factors for readmissions after shoulder replacement surgeries

Shoulder replacement is the third most common joint-replacement surgery in the U.S. and is likely to become more common as the population ages, according to Penn State researchers.

17 Mar 2026

Extended monitoring identifies many more severe pregnancy complication cases

Extending the monitoring period for severe pregnancy complications showed more than 40% of cases were missed using traditional delivery-focused monitoring, according to new research published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.251425 that extended monitoring from conception to 6 weeks postpartum.

16 Mar 2026

Improving the survival odds for emergency urology patients

One in ten emergency patients with visible blood in their urine die within three months of presenting at A&E, new research has found.

16 Mar 2026

High fat diets allow gut bacteria to enter the brain via the vagus nerve

With more than 100 million neurons in the digestive tract, the gut is commonly known as the "second brain" in numerous cultures, including ancient Greece, Japan, China and India, linking digestion with physical and mental well-being.

12 Mar 2026

The 0.05 EU/mg breakthrough: How Sino Biological ProPure™ is redefining the Ultra-Low Endotoxin standard

When we discuss bacterial infections, we often think of exotoxins—those soluble proteins actively secreted by bacteria—while overlooking endotoxins, which are more insidious but equally dangerous.

From Sino Biological Inc. 12 Mar 2026

Maternal antibodies protect newborns from severe E. coli infections, study finds

A multi-center study led by researchers at Cincinnati Children's sheds surprising new light on why some newborns become severely ill from Escherichia coli infection, but others do not.

11 Mar 2026

Single receptor PAR1 controls opposing responses in blood vessels

Researchers at the University of California San Diego have uncovered how a single protein triggers two opposite responses in blood vessels - one inflammatory and one protective.

10 Mar 2026

Low-cost interventions reduce neonatal sepsis from Klebsiella pneumoniae

A new study found that a multifaceted infection prevention and control intervention could at least temporarily thwart outbreaks of infections from the Klebsiella pneumoniae bacterium, a leading cause of neonatal sepsis and mortality in Africa and South Asia.

10 Mar 2026

Researchers identify TRIM13 protein as key driver of immune suppression in sepsis

Dendritic cells (DCs) are increasingly recognized as important contributors to sepsis-associated immune dysfunction.

4 Mar 2026

Gut microbiota-derived metabolite directly shapes immune responses in bacterial pneumonia

Sepsis and severe pneumonia are frequently accompanied by disruption of the gut microbiota, leading to immune dysfunction and increased susceptibility to secondary infections.

4 Mar 2026