Sepsis

Sepsis is a life-threatening illness. Your body's response to a bacterial infection usually causes it. Your immune system goes into overdrive, overwhelming normal processes in your blood. The result is that small blood clots form, blocking blood flow to vital organs. This can lead to organ failure. Babies, old people and those with weakened immune systems are most likely to get sepsis. But even healthy people can become deathly ill from it.

Everything You Need To Know About Sepsis

Sepsis is a life-threatening systemic response to an infection. This article provides an overview of sepsis, including stages, diagnosis and treatment.

Sepsis Diagnosis

Causes and Symptoms of Sepsis in Newborns

Diagnosis and Treatment of Sepsis in Newborns

Sepsis Prevention

Recovering from Sepsis

Sepsis Epidemiology

Sepsis Pathophysiology

Sepsis at the Molecular Level

Sepsis and Pregnancy

Sepsis: Identifying the Signs and Administering First Aid

Acute Respiratory Distress Syndrome (ARDS) and Sepsis

See more featured articles »

Sepsis Complications and Prevention

The Stages of Sepsis

How Antimicrobial Resistance Amplifies the Burden of Sepsis

Lactate Levels and Sepsis

Sepsis and Influenza

Sepsis History

The Development of a Sepsis Scoring System in a Murine Model

Latest Sepsis News and Research

Antimalarial drug shows in vitro activity against SARS-CoV-2 and flu viruses

Now, a new study published in the preprint server bioRxiv in July 2020 reports on the antiviral activity of two drugs found in an antimalarial drug currently in phase II trials in South Korea, called Pyramax.

30 Jul 2020

Higher levels of TGFBIp are correlated with severity of COVID-19 symptoms

A new study found raised levels of transforming growth factor beta-induced protein (TGFBIp) in blood sampled from roughly 100 people hospitalized for COVID-19, and further found that elevated levels of both the normal and acetylated forms of TGFBIp correlated with the severity of disease symptoms in these patients.

25 Jul 2020

Researcher receives Outstanding Investigator Award for groundbreaking microvascular and circulation research

Sarah Yuan, MD, PhD, professor and chair of the Department of Molecular Pharmacology and Physiology at the USF Health Morsani College of Medicine, has received a highly competitive National Heart, Lung, and Blood Institute (NHLBI) Outstanding Investigator Award to continue breaking new ground in microvascular and circulation research.

25 Jul 2020

Patients with frailty, older age and UTIs have higher risk of developing sepsis

Patients with frailty, older age and urinary tract infections are at greatest risk of developing sepsis following infection consultations in primary care, research has found.

24 Jul 2020

Study finds increasing rates of preventable hospitalizations among dementia patients

Older adults with dementia tend to be hospitalized more often than those without cognitive impairment.

24 Jul 2020

SphingoTec launches point-of-care test for bio-ADM, a biomarker for life threatening endothelial dysfunction

Diagnostics company SphingoTec GmbH today announced the launch of its IB10 sphingotest® bio-ADM®, a CE-IVD-marked point-of-care test to quantitatively determine blood levels of Bioactive Adrenomedullin. Blood levels of bio-ADM® reflect in real-time the functional status of the endothelium, the inner cell sheet of blood vessels.

24 Jul 2020

SphingoTec introduces a CE-IVD-marked point-of-care test to determine blood levels of bio-ADM

Diagnostics company SphingoTec GmbH today announced the launch of its IB10 sphingotest bio-ADM, a CE-IVD-marked point-of-care test to quantitatively determine blood levels of Bioactive Adrenomedullin (bio-ADM).

22 Jul 2020

Groundbreaking technology could enhance therapeutic efficiency of nanomedicines

Researchers from the Moscow Institute of Physics and Technology and their colleagues from Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry and Prokhorov General Physics Institute of the Russian Academy of Sciences have developed a breakthrough technology to resolve a key problem that has prevented the introduction of novel drugs into clinical practice for decades.

17 Jul 2020

Study shows immediate dialysis is no better than the conservative approach

In the largest international study of its kind, researchers at the University of Alberta and Toronto's St. Michael's Hospital found that an accelerated renal-replacement therapy strategy did not reduce mortality after three months, compared to a standard strategy for critically ill patients with acute kidney injury.

17 Jul 2020

CBD may help reduce cytokine storm and excessive lung inflammation in COVID-19

Cannabidiol, or CBD, may help reduce the cytokine storm and excessive lung inflammation that is killing many patients with COVID-19, researchers say.

16 Jul 2020

COVID-19 – researchers sum up the “Tsunami” of information

The severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) infection leading to COVID-19 is a raging pandemic across the world at present. It has infected 13 million and killed 571,000 individuals around the world as of today. The infection was first reported in Wuhan, Hubei Province of China in late December 2019.

13 Jul 2020

Clots, COVID-19 and survival

The novel coronavirus, now known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), that causes COVID-19 disease, was first reported in Wuhan, Hubei Province of China in late December 2019. Since then, it has infected a large population across the world with the current number of SARS-CoV-2 infections standing at over 13 million and COVID-19 disease having killed over 571,000 individuals.

13 Jul 2020

Bird poop may harbor abundant antibiotic resistance genes

Bird poop may pose more health risks than people realize, according to Rice University environmental engineers who study antibiotic resistance.

13 Jul 2020

Delirium linked to long-term cognitive decline

A new meta-analysis of 24 observational studies from researchers at Columbia University Vagelos College of Physicians and Surgeons found that delirium may cause significant long-term cognitive decline.

13 Jul 2020

No unique viral sequences found in pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2

In contrast to previous hypotheses, researchers from the University College London and Great Ormond Street Hospital for Children NHS Foundation Trust found no evidence of unique viral sequences from patients with pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS). Their study is published on the medRxiv* preprint server.

12 Jul 2020

Manifestations of COVID-19 in newborn babies

In a new study titled, “The clinical course of SARS-CoV-2 positive neonates,” Italian researchers led by Guiseppe De Bernado from Division of Pediatrics Neonatology and NICU, Ospedale Buon Consiglio Fatebenefratelli, Naples, explain the course of the infection among newborn babies.

9 Jul 2020

Highly effective and safe nanocrystal can fight against dangerous doses of radiation

Despite the wide application of radiation in diagnostics and treatments, there is still no magic material to protect people from radiation exposure.

6 Jul 2020

Oral hygiene and severity of COVID-19 – the connection

Their study titled, “Could there be a link between oral hygiene and the severity of SARS-CoV-2 infections?” was published in the latest issue of the journal British Dental Journal.

30 Jun 2020

Live attenuated vaccines may prevent lung inflammation and sepsis associated with COVID-19

A paper published by Paul Fidel, Jr., PhD, Professor and Director of the Center of Excellence in Oral and Craniofacial Biology and Associate Dean for Research at LSU Health New Orleans School of Dentistry, and Mairi Noverr, PhD, Professor of Microbiology & Immunology at Tulane University School of Medicine in New Orleans, suggests that live attenuated vaccines such as MMR (measles, mumps and rubella) may prevent the severe lung inflammation and sepsis associated with COVID-19 infection.

26 Jun 2020

Race, rurality play huge role in Georgia areas hardest hit by COVID-19

While counties in populous metropolitan Atlanta had the highest number of COVID-19 cases in the initial weeks following Georgia's first reported case, it was rural Southwest Georgia counties, with a higher number of black residents and lower number of ICU beds, experiencing the highest rates of infection and death per capita, investigators report.

25 Jun 2020