Sepsis

Sepsis is a life-threatening illness. Your body's response to a bacterial infection usually causes it. Your immune system goes into overdrive, overwhelming normal processes in your blood. The result is that small blood clots form, blocking blood flow to vital organs. This can lead to organ failure. Babies, old people and those with weakened immune systems are most likely to get sepsis. But even healthy people can become deathly ill from it.

Everything You Need To Know About Sepsis

Sepsis is a life-threatening systemic response to an infection. This article provides an overview of sepsis, including stages, diagnosis and treatment.

Sepsis Complications and Prevention

The Stages of Sepsis

Sepsis Pathophysiology

Lactate Levels and Sepsis

Sepsis Prevention

How Antimicrobial Resistance Amplifies the Burden of Sepsis

Recovering from Sepsis

Sepsis Diagnosis

Causes and Symptoms of Sepsis in Newborns

Sepsis Epidemiology

Sepsis and Influenza

See more featured articles »

Sepsis History

Sepsis: Identifying the Signs and Administering First Aid

Sepsis and Pregnancy

Diagnosis and Treatment of Sepsis in Newborns

The Development of a Sepsis Scoring System in a Murine Model

Acute Respiratory Distress Syndrome (ARDS) and Sepsis

Sepsis at the Molecular Level

Latest Sepsis News and Research

E. coli in retail meat linked to thousands of urinary infections

Research reveals a significant link between E. coli in meat and urinary tract infections, particularly in vulnerable communities in Southern California.

28 Oct 2025

Leveraging the microbiome to promote healthy living and aging

From probiotic pills to skincare products to dedicated meal plans, the microbiome is all the rage in the health and wellness space.

21 Oct 2025

New AI system connects hidden clues in medical records to transform diagnosis

Doctors often must make critical decisions in minutes, relying on incomplete information. While electronic health records contain vast amounts of patient data, much of it remains difficult to interpret quickly-especially for patients with rare diseases or unusual symptoms.

15 Oct 2025

New wearable sensor tracks vitamin B6 levels in sweat

Vitamin B6, which is absorbed from a broad range of foods, helps bolster immune system function and neurotransmitters in the brain.

14 Oct 2025

Global antibiotic resistance reaches alarming levels in 2023

One in six laboratory-confirmed bacterial infections causing common infections in people worldwide in 2023 were resistant to antibiotic treatments, according to a new World Health Organization (WHO) report launched today.

14 Oct 2025

Study validates AI models for preemptive sepsis care in pediatrics

Sepsis, or infection causing life-threatening organ dysfunction, is a leading cause of death in children worldwide. In efforts to prevent this rare but critical condition, researchers developed and validated AI models that accurately identify children at high risk for sepsis within 48 hours, so that early preemptive care can be provided.

13 Oct 2025

Understanding the impact of chikungunya on children

Chikungunya is a vector-borne disease that affects both adults and children. While global efforts are ongoing to tackle chikungunya in adults, progress in addressing pediatric chikungunya remains inadequate.

10 Oct 2025

Decoding the signaling networks and metabolic dysregulation underlying sepsis

Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction.

10 Oct 2025

X-HiDE project advances toward earlier detection and precision treatment of inflammatory diseases

Facilitating earlier diagnosis and more precise treatment for patients with inflammatory diseases. This is the goal as the X-HiDE research project at örebro University in Sweden now enters its next phase, in collaboration with eleven companies and four other universities in Europe and the USA.

8 Oct 2025

State-of-the-art microchips help understand how sepsis and neurodegenerative diseases damage the brain

In lieu of animal experiments, researchers from the University of Rochester are using state-of-the-art microchips with human tissue to better understand how the brain operates under healthy conditions and is damaged through neurodegenerative diseases or conditions like sepsis.

7 Oct 2025

New immune system assessment tool could help guide critical care treatment

When a patient enters the emergency department in critical condition, doctors must quickly run through a crucial list of questions: Does the patient have an infection? If so, is it bacterial or viral? Do they require treatment? Can the patient recover at home safely or do they need to be hospitalized?

30 Sep 2025

Doctors with troubled pasts are performing cosmetic surgeries tied to crippling pain and injury

Not long after California surgeon Andrew S. Hsu landed a job with a cosmetic surgery chain in Georgia, several of his patients suffered disfiguring injuries, and even his new employer had doubts about his competence, court records allege.

30 Sep 2025

Can roselle help fight inflammation? New review suggests strong potential

A new review highlights the anti-inflammatory potential of Hibiscus sabdariffa (roselle), synthesizing evidence from 25 studies published between 2019 and 2024. Most findings are from preclinical models, but they point to promising roles in cardiovascular, metabolic, neuroprotective, and anticancer health.

28 Sep 2025

Infant mortality rate rises sharply when mothers experience pregnancy-associated death

A new study found that infant mortality rates in Massachusetts were 14 times higher among babies whose mother experienced a pregnancy-associated death than among babies whose mother survived pregnancy and postpartum.

26 Sep 2025

Frontline clinicians report trauma patterns in Gaza exceeding previous warzones

A British led study published by The BMJ today provides detailed data on the pattern and severity of traumatic injuries and medical conditions seen by international healthcare workers deployed to Gaza during the ongoing military invasion.

25 Sep 2025

Study reveals how a little-understood protein contributes to blood vessel leakage

A new study from the University of Oklahoma reveals how a little-understood protein, CD82, contributes to blood vessel leakage, a process that initiates inflammation but becomes dangerous when it occurs during severe inflammatory diseases such as sepsis, acute respiratory distress syndrome and COVID-19.

18 Sep 2025

Younger adults and men with type 2 diabetes face higher risk of sepsis

Living with type 2 diabetes (T2D) may double the risk of developing sepsis-with those aged younger than 60 years and men particularly susceptible, according to a long-term community-based study in Australia, being presented at this year's Annual Meeting of The European Association for the Study of Diabetes (EASD), Vienna (15-19 Sept).

16 Sep 2025

Targeting complement with an inhibitor may prevent preterm birth and protect the baby’s brain

A research team at the Medical University of South Carolina reports in Cells that the complement system, part of the body's natural immune defenses, is a key driver of inflammatory responses that contribute to fetal brain inflammation and preterm birth, the latter of which is the leading cause of complications and death in newborns.

4 Sep 2025

Penn State team develops wearable sensor to track health through minimal sweat

Available on-demand, in abundance and containing multiple biomarkers, sweat is an increasingly appealing medium for monitoring health, according to researchers at Penn State.

3 Sep 2025