Sepsis

Sepsis is a life-threatening illness. Your body's response to a bacterial infection usually causes it. Your immune system goes into overdrive, overwhelming normal processes in your blood. The result is that small blood clots form, blocking blood flow to vital organs. This can lead to organ failure. Babies, old people and those with weakened immune systems are most likely to get sepsis. But even healthy people can become deathly ill from it.

Everything You Need To Know About Sepsis

Sepsis is a life-threatening systemic response to an infection. This article provides an overview of sepsis, including stages, diagnosis and treatment.

Sepsis Diagnosis

Recovering from Sepsis

The Stages of Sepsis

Diagnosis and Treatment of Sepsis in Newborns

Causes and Symptoms of Sepsis in Newborns

Lactate Levels and Sepsis

Sepsis: Identifying the Signs and Administering First Aid

Sepsis History

How Antimicrobial Resistance Amplifies the Burden of Sepsis

Sepsis and Pregnancy

Sepsis and Influenza

See more featured articles »

Sepsis Epidemiology

The Development of a Sepsis Scoring System in a Murine Model

Sepsis Pathophysiology

Acute Respiratory Distress Syndrome (ARDS) and Sepsis

Sepsis at the Molecular Level

Sepsis Prevention

Sepsis Complications and Prevention

Latest Sepsis News and Research

Cranberry juice may help stop antibiotic resistance in UTIs

Cranberry juice potentiates fosfomycin against UPEC, lowering resistance rates and modifying bacterial absorption pathways for improved antibiotic efficacy.

7 May 2026

KIF13B protects heart function during sepsis by regulating lipid metabolism

Sepsis, a life-threatening condition caused by dysregulated host response to infection, remains a major cause of global mortality.

5 May 2026

Advanced AI models outperform pediatricians in diagnosing rare diseases

Artificial intelligence (AI) is increasingly being explored as a tool to support clinical decision-making, yet its real-world performance in pediatric diagnosis remains unclear.

4 May 2026

How a common gut bacterium may protect health

Akkermansia muciniphila's impact on immunity and pregnancy outcomes underscores its promise as a probiotic, with implications for infectious disease treatment.

4 May 2026

Noninvasive brain monitoring reveals hidden oxygen deprivation in ICU patients

In neurological intensive care, it is quickly learned that the brain cannot wait. As the most sensitive organ in the human body, it can sustain irreversible damage after just a few minutes of severe hypoxia.

27 Apr 2026

Study finds different types of crystalloid fluids are equally effective for pediatric sepsis

A major study, led by researchers at Children's Hospital of Philadelphia, Nemours Children's Health, and Children's National Hospital and involving an extensive network of medical centers across the United States and abroad, found that different types of crystalloid fluid resuscitation were equally effective for staving off the most serious adverse kidney events after the treatment of pediatric patients with suspected septic shock.

25 Apr 2026

New fiber probe enables real-time monitoring of key biomarkers

A new fiber probe developed by researchers at The University of Texas at Austin delivers two major innovations in health monitoring to help both patients around the world and the clinicians who care for them.

22 Apr 2026

WHO-recommended antibiotics ineffective for many neonatal sepsis cases

A major multi-country study has found that WHO-recommended first-line antibiotics for neonatal sepsis are likely to be effective in only one quarter of infections in low- and middle-income countries (LMICs).

20 Apr 2026

Review identifies TREM-1 as key amplifier of inflammatory diseases

Published in Current Molecular Pharmacology, a comprehensive review by Eman R. Al Sawy and colleagues from Cairo University consolidates evidence on the triggering receptor expressed on myeloid cells-1 (TREM-1) as a central amplifier of inflammatory responses.

7 Apr 2026

Fecal microbiota transplant can improve survival in severe C. difficile infection

A new study from the University of Minnesota Medical School demonstrated that fecal microbiota transplantation (FMT) can rapidly reverse systemic inflammation and improve survival in patients with fulminant Clostridioides difficile (C. difficile) infection - a life-threatening condition characterized by a sepsis-like state.

6 Apr 2026

New urine test shows which UTI antibiotic works in under six hours

Researchers have developed a rapid direct-from-urine test that identifies which first-line antibiotic is likely to work for a urinary tract infection in an average of 5.85 hours, instead of the usual two to three days. In studies of 352 routine urine samples and 90 duplicate preservative-tested samples, the method showed high agreement with standard testing, suggesting it could speed treatment and support efforts to curb antimicrobial resistance.

30 Mar 2026