Sepsis News and Research

Latest Sepsis News and Research

High fat diets allow gut bacteria to enter the brain via the vagus nerve

With more than 100 million neurons in the digestive tract, the gut is commonly known as the "second brain" in numerous cultures, including ancient Greece, Japan, China and India, linking digestion with physical and mental well-being.

12 Mar 2026

The 0.05 EU/mg breakthrough: How Sino Biological ProPure™ is redefining the Ultra-Low Endotoxin standard

When we discuss bacterial infections, we often think of exotoxins—those soluble proteins actively secreted by bacteria—while overlooking endotoxins, which are more insidious but equally dangerous.

From Sino Biological Inc. 12 Mar 2026

Maternal antibodies protect newborns from severe E. coli infections, study finds

A multi-center study led by researchers at Cincinnati Children's sheds surprising new light on why some newborns become severely ill from Escherichia coli infection, but others do not.

11 Mar 2026

Single receptor PAR1 controls opposing responses in blood vessels

Researchers at the University of California San Diego have uncovered how a single protein triggers two opposite responses in blood vessels - one inflammatory and one protective.

10 Mar 2026

Low-cost interventions reduce neonatal sepsis from Klebsiella pneumoniae

A new study found that a multifaceted infection prevention and control intervention could at least temporarily thwart outbreaks of infections from the Klebsiella pneumoniae bacterium, a leading cause of neonatal sepsis and mortality in Africa and South Asia.

10 Mar 2026

Researchers identify TRIM13 protein as key driver of immune suppression in sepsis

Dendritic cells (DCs) are increasingly recognized as important contributors to sepsis-associated immune dysfunction.

4 Mar 2026

Gut microbiota-derived metabolite directly shapes immune responses in bacterial pneumonia

Sepsis and severe pneumonia are frequently accompanied by disruption of the gut microbiota, leading to immune dysfunction and increased susceptibility to secondary infections.

4 Mar 2026

MERLIN algorithm unlocks immune cell location memory in organs

A new AI-based method reconstructs spatial information about where immune cells were originally located in an organ, even after these cells have been removed from the tissue and analyzed individually.

2 Mar 2026

$8.7 million award supports faster genetic diagnosis of lymphatic diseases

A team of researchers led by Columbia University Vagelos College of Physicians and Surgeons has been awarded an up to two-year $8.7 million contract from the Advanced Research Projects Agency for Health (ARPA-H) to create genetic tests to speed the diagnosis of patients born with defects in the lymphatic system.

19 Feb 2026

Review: Pathogenesis, diagnosis, and management of harlequin ichthyosis

Harlequin ichthyosis (HI) is a rare, severe genetic skin disorder caused by ABCA12 mutations, leading to defective lipid transport and loss of skin barrier function.

17 Feb 2026

Engineered Listeria boosts innate immunity against cancer

After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system to cause listeriosis, Daniel Portnoy and his colleagues have discovered a way to turn the bacteria into a potent booster of the immune system - and a potential weapon against cancer.

13 Feb 2026

Early tuberculosis treatment reduces sepsis deaths in HIV patients

Sepsis is a leading global cause of hospital deaths, occurring when the body's response to infection damages tissue and causes organs to fail. Africa bears the world's highest burden of sepsis, with an estimated 48 million cases each year leading to about 11 million deaths.

7 Feb 2026

Artificial lung keeps patient alive after lung removal

Researchers evaluate the effectiveness of a novel extracorporeal total artificial lung system to enable bilateral pneumonectomy in patients with severe ARDS.

5 Feb 2026

Early TB treatment before sepsis diagnosis could save countless lives

Tuberculosis (TB) is a major unrecognized cause of deadly sepsis among people with HIV in Africa, a sweeping new study reveals. Beginning treatment for TB immediately – even before sepsis patients are diagnosed with TB – could save countless lives, the researchers say.

30 Jan 2026

New mode of communication inside cells helps bacterial pathogens to evade drugs

Biologists have uncovered a new mode of communication inside cells that helps bacterial pathogens learn how to evade drugs.

30 Jan 2026

New guide for clinicians aims to improve UTI care

Millions of times a year, Americans seek urgent treatment for painful, embarrassing urinary tract infections.

29 Jan 2026

Scientists discover a non-classical platelet mechanism linked to severe infections

Platelets are small, anucleate blood cells that play an essential role in hemostasis. Their primary task is to recognize vascular injury, become activated, and aggregate via their surface receptor integrin αIIbβ3. This leads to the formation of a stable platelet plug that seals the wound and stops bleeding. When this process becomes dysregulated, however, it can result in vessel-occluding clots - so-called thromboses - which may cause myocardial infarction or stroke.

23 Jan 2026