Sepsis News and Research

Latest Sepsis News and Research

Universal consensus definition unlocks research advancements for critically ill children worldwide

St. Jude Children's Research Hospital investigators collaborated with a global group of acute pediatric critical illness experts to reach a consensus definition of the condition.

9 Jan 2024

Three cytokine pairs found to be responsible for the body's damaging response to sepsis

Sepsis -; when an infection causes the immune system to improperly target the body -; is one of the leading causes of death in the ICU.

8 Jan 2024

Early pandemic sees drop in child UTI diagnoses, severity unchanged

A cohort study in JAMA Network Open found a decrease in urinary tract infection (UTI) diagnoses among children during the early COVID-19 pandemic without an increase in disease severity, suggesting a potential reduction in over- or misdiagnosis.

4 Jan 2024

New compound effective against bacterial species resistant to multiple classes of existing antibiotics

Recent studies by Zampaloni et al. and Pahil et al. published in the journal Nature describe a novel method of inhibiting the growth of Gram-negative bacteria such as Acinetobacter using antibiotics consisting of macrocyclic peptides that target the bacterial protein bridge machinery that transports lipopolysaccharides from the cytoplasm to the outer membrane.

4 Jan 2024

Human vs. cow's milk fortifier in preterm infants: No significant outcome difference, study finds

Study compares the effects of feeding extremely preterm infants with human milk fortified with either human milk-based fortifier (HMBF) or cow's milk-based fortifier (BMBF), finding no significant difference in the incidence of necrotizing enterocolitis, sepsis, or death.

3 Jan 2024

New Pfizer/BioNTech vaccine variant shows enhanced protection against COVID-19 hospitalization

Study demonstrates that the BNT162b2 SARS-CoV-2 XBB1.5 variant-modified vaccine significantly reduces the risk of COVID-19-related hospitalizations and ambulatory visits, outperforming previous vaccine versions in the face of evolving virus strains.

2 Jan 2024

Large study debunks hope for breast milk-based enrichment in preterm care

Infants born extremely prematurely need to get enrichment as an addition to breast milk. But does it make any difference whether the enrichment is made from breast milk or cow's milk when it comes to the risk of severe complications in children?

2 Jan 2024

New insights on better diagnosis and treatment of ischemic cholecystitis

Ischemic cholecystitis is a form of gallbladder inflammation that occurs without gallstones or another form of external compression.

28 Dec 2023

Sepsis greatly reduces the chances of returning to work, study finds

A few years ago, the World Health Organization estimated that blood poisoning, or sepsis, is involved in one in five deaths in the world. 11 million people die from sepsis each year, of which nearly 3 million are children.

28 Dec 2023

Common inflammation pathway turns anthrax toxin into killer

Bacillus anthracis lethal toxin (LT) is a determinant of lethal anthrax. Its function in myeloid cells is required for bacterial dissemination, and LT itself can directly trigger dysfunction of the cardiovascular system.

26 Dec 2023

First new antibiotic class in decades discovered using explainable AI platform

Scientists have discovered one of the first new classes of antibiotics identified in the past 60 years, and the first discovered leveraging an AI-powered platform built around explainable deep learning.

20 Dec 2023

From diabetes drug to anti-inflammation powerhouse: The unexpected evolution of GLP-1

Research pioneer Dr. Daniel Drucker has much to be proud of, as the GLP-1-based diabetes drugs hailing from his early research are named 2023 breakthrough of the year by the Science Magazine.

18 Dec 2023

Phase I clinical trial of new CAR T cell therapy AT101 shows promising early responses

Early results from a Phase I clinical trial of AT101, a new CAR T cell therapy that uses a distinct binding mechanism to target CD19, show a 100 percent complete response (CR) rate at the higher dose levels studied in the trial, according to researchers from the University of Pennsylvania Perelman School of Medicine and Penn Medicine's Abramson Cancer Center.

11 Dec 2023

COVID-19 significantly raises risk of severe complications in pregnant women

Study found that pregnant mothers with COVID-19 face a significantly higher risk of severe maternal morbidity (SMM), including adult respiratory distress syndrome and acute renal failure, emphasizing the urgent need for their early diagnosis and treatment.

10 Dec 2023

Study links placental Group B Streptococcus to higher neonatal unit admissions in newborns

The clinical significance of Streptococcus agalactiae (Group B Streptococcus; GBS) deoxyribonucleic acid (DNA) in the placenta.

4 Dec 2023

Balanced IV fluids can reduce death risk for critically ill patients

Results of a new meta-analysis in shows that intravenous fluid (IV) therapy using balanced solutions rather than commonly used saline can reduce the risk of in-hospital death of critically ill patients by four percent.

30 Nov 2023

The impact of implementing a high sensitivity assay for cardiac troponin I on long term outcomes in patients with suspected acute coronary syndrome

Researchers from the United Kingdom evaluated the use of a high-sensitivity assay to measure cardiac troponin I and its impact on myocardial infarction (MI) risk or other long-term outcomes such as death at five years in individuals with suspected acute coronary syndrome.

30 Nov 2023

Associations between socioeconomic status, clinical variables, and non-COVID-19 sepsis risk

The impact of socioeconomic status and clinical variables on sepsis incidence and mortality.

28 Nov 2023

Novel AI-powered method detects antimicrobial resistance within 30 minutes

To mark World Antimicrobial Awareness Week, researchers supported by the Oxford Martin Programme on Antimicrobial Resistance Testing (University of Oxford) have reported advances towards a novel and rapid antimicrobial susceptibility test that can return results within as little as 30 minutes.

22 Nov 2023

Green tea-silver nanoparticles: A promising weapon against superbugs

Once upon a time, people believed to be invincible against bacterial diseases, thanks to the antibiotics. Does this sound like a fairy tale? By all means! Nothing could be further from the truth.

17 Nov 2023

Sepsis News and Research

Latest Sepsis News and Research

Universal consensus definition unlocks research advancements for critically ill children worldwide

Three cytokine pairs found to be responsible for the body's damaging response to sepsis

Early pandemic sees drop in child UTI diagnoses, severity unchanged

New compound effective against bacterial species resistant to multiple classes of existing antibiotics

Human vs. cow's milk fortifier in preterm infants: No significant outcome difference, study finds

New Pfizer/BioNTech vaccine variant shows enhanced protection against COVID-19 hospitalization

Large study debunks hope for breast milk-based enrichment in preterm care

New insights on better diagnosis and treatment of ischemic cholecystitis

Sepsis greatly reduces the chances of returning to work, study finds

Common inflammation pathway turns anthrax toxin into killer

First new antibiotic class in decades discovered using explainable AI platform

From diabetes drug to anti-inflammation powerhouse: The unexpected evolution of GLP-1

Phase I clinical trial of new CAR T cell therapy AT101 shows promising early responses

COVID-19 significantly raises risk of severe complications in pregnant women

Study links placental Group B Streptococcus to higher neonatal unit admissions in newborns

Balanced IV fluids can reduce death risk for critically ill patients

The impact of implementing a high sensitivity assay for cardiac troponin I on long term outcomes in patients with suspected acute coronary syndrome

Associations between socioeconomic status, clinical variables, and non-COVID-19 sepsis risk

Novel AI-powered method detects antimicrobial resistance within 30 minutes

Green tea-silver nanoparticles: A promising weapon against superbugs

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Sepsis News and Research

Latest Sepsis News and Research

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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