Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Vaccination drives superior functional antibody breadth compared to natural infection with SARS-CoV-2

Researchers assessed the potency and breadth of antibody recognition and effector function among healthy and high-risk individuals following natural SARS-CoV-2 infection or mRNA COVID-19 vaccination.

21 Sep 2022

New antiviral mechanism of action for an FDA-approved thiopurine known as 6-thioguanine

Researchers described a novel antiviral mechanism of action for an FDA (food and drug administration)-approved thiopurine known as 6-thioguanine (6-TG).

21 Sep 2022

Prophylactic administration of SARS-CoV-2 specific immunoglobulin Y generated in chicken eggs displays protective effects in infected mice

A new study characterized and tested the antibody activity of SARS-CoV-2-specific immunoglobulin Y (IgY) derived from the eggs laid by chickens immunized with recombinant SARS-CoV-2 receptor binding domain (RBD) protein.

21 Sep 2022

Researchers report development of a self-assembled trimeric RBD subunit vaccine able to prevent SARS-CoV-2 infection

The present study reported the development of a new self-assembled trimeric RBD subunit vaccine that could effectively prevent infection from SARS-CoV-2 variants, including the currently dominantly circulating Omicron variant.

21 Sep 2022

Study reveals improved immunogenicity and safety of bivalent Omicron-containing mRNA-1273.214 candidate booster vaccine

In a new study, a team of researchers assessed the safety and efficacy of a bivalent candidate vaccine containing spike messenger ribonucleic acids of the ancestral Wuhan-Hu-1 strain and the Omicron B.1.1.529 [BA.1] variant of SARS-CoV-2.

21 Sep 2022

Why fatigue from long COVID goes beyond simply feeling tired

In a recent study posted to the medRxiv* preprint server, researchers in the Netherlands examined the role of inflammatory genes, cytotoxic T-lymphocytes (CD8+ T cells), and pro-inflammatory cytokines in long-lasting severe fatigue experienced by a large number of coronavirus disease 2019 (COVID-19) patients.

21 Sep 2022

Study reveals increased immunity evasion by Omicron BA.2.75.2

In a recent study posted to the bioRxiv* preprint server, researchers from ETH Zurich, Imperial College London, and Karolinska Institutet identified increased resistance to antibody-mediated neutralization by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineage BA.2.75.2.

21 Sep 2022

Study shows COVID-19 activity peaks during winter in the United States and Europe

In a recent study posted to the Research Square* preprint server, researchers from Columbia University Mailman School of Public Health, Pfizer Inc, and the University of Iowa assessed the seasonal trends observed in coronavirus disease 2019 (COVID-19) cases, hospitalizations, and deaths.

21 Sep 2022

Clinical and epidemiologic features of SARS-CoV-2 in companion animals

In a recent study posted to the Research Square* preprint server, researchers explored the clinical and epidemiologic characteristics of coronavirus disease 2019 (COVID-19) in dogs and cats.

21 Sep 2022

SARS-CoV-2 generates amyloid in cerebral spinal fluid

In a recent study posted to the bioRxiv* preprint server, an international team of researchers demonstrated amyloid aggregation due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human cerebrospinal fluid (CSF).

20 Sep 2022

No adverse affect on sperm quality 6 to 14 months post BNT162b2 COVID vaccine

A study published in the journal Gamete Biology demonstrates that the mRNA-based coronavirus disease 2019 (COVID-19) vaccine developed by Pfizer/BioNTech is not detrimental to sperm health over a long period post-vaccination.

20 Sep 2022

Vaccination-induced responses for Omicron subvariant neutralization

Researchers summarized existing data on SARS-CoV-2 Omicron variant’s sub-variant (BA.1, BA.1.1, BA.2, BA.2.12.1, BA.3, and BA.4/5) neutralization. They also performed a comparative assessment of cross-neutralizing responses of Omicron subvariants in comparison to the Wuhan-Hu-1 strain (prototype) antigen.

20 Sep 2022

Healthcare systems seem may be ill-equipped to handle high co-circulation of influenza and SARS-CoV-2 in the coming year

In a new study, researchers conducted a community-based prospective cohort study in Managua, Nicaragua, before the winter season when influenza A (H3N2) cases surge in the Northern Hemisphere.

20 Sep 2022

What are the 2-year health outcomes among patients hospitalized for COVID-19 in China?

A recent study assessed the dynamic trajectory of COVID-19 symptom burden as well as symptom persistence in those who survived SARS-CoV-2 infection for two years after being discharged from hospitals.

20 Sep 2022

Neutralizing antibody responses, breakthrough SARS-CoV-2 infections, and symptoms after booster BNT162b2 COVID-19 vaccinations

A new study evaluated neutralizing antibody (nAb) responses against the SARS-CoV-2 Omicron variant induced by booster vaccination with Pfizer-BioNTech’s BNT162b2 messenger ribonucleic acid vaccine.

20 Sep 2022

Regular fish oil consumption found effective in preventing severe COVID-19 outcomes

In a new study, researchers investigated whether regular fish oil use decreased the risk of contracting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

20 Sep 2022

New mechanistic insights on the origin of SARS-CoV-2-induced neurological disorders

Researchers explored the effect of SARS-CoV-2 exposure on the brain.

20 Sep 2022

The potential of nanobody engineering in the development of SARS-CoV-2 antivirals and diagnostic tools

Researchers investigated nanobody engineering to develop antivirals and diagnostic tools against SARS-CoV-2.

20 Sep 2022

Endogenous exosomes act as decoys for SARS-CoV-2

A recent study published in the journal PLoS Biology discussed exosomes as potential decoys for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

20 Sep 2022

Molecular engineered low-cost highly effective RBD-based COVID vaccine

In a recent study posted to the bioRxiv* preprint server, an international team of researchers developed a second-generation severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor binding domain (RBD) antigen (RBD-J6) by molecular engineering with two additional amino acid (aa) substitutions (S383D and L518D mutations) in a hydrophobic cryptic RBD core epitope to enhance stability and expression against SARS-CoV-2 variants of concern (VOCs).

19 Sep 2022

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Vaccination drives superior functional antibody breadth compared to natural infection with SARS-CoV-2

New antiviral mechanism of action for an FDA-approved thiopurine known as 6-thioguanine

Prophylactic administration of SARS-CoV-2 specific immunoglobulin Y generated in chicken eggs displays protective effects in infected mice

Researchers report development of a self-assembled trimeric RBD subunit vaccine able to prevent SARS-CoV-2 infection

Study reveals improved immunogenicity and safety of bivalent Omicron-containing mRNA-1273.214 candidate booster vaccine

Why fatigue from long COVID goes beyond simply feeling tired

Study reveals increased immunity evasion by Omicron BA.2.75.2

Study shows COVID-19 activity peaks during winter in the United States and Europe

Clinical and epidemiologic features of SARS-CoV-2 in companion animals

SARS-CoV-2 generates amyloid in cerebral spinal fluid

No adverse affect on sperm quality 6 to 14 months post BNT162b2 COVID vaccine

Vaccination-induced responses for Omicron subvariant neutralization

Healthcare systems seem may be ill-equipped to handle high co-circulation of influenza and SARS-CoV-2 in the coming year

What are the 2-year health outcomes among patients hospitalized for COVID-19 in China?

Neutralizing antibody responses, breakthrough SARS-CoV-2 infections, and symptoms after booster BNT162b2 COVID-19 vaccinations

Regular fish oil consumption found effective in preventing severe COVID-19 outcomes

New mechanistic insights on the origin of SARS-CoV-2-induced neurological disorders

The potential of nanobody engineering in the development of SARS-CoV-2 antivirals and diagnostic tools

Endogenous exosomes act as decoys for SARS-CoV-2

Molecular engineered low-cost highly effective RBD-based COVID vaccine

Innovation in neuroscience drug discovery - eBook eBook

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Shaping the future of lab automation through AI and robotics

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Innovation in neuroscience drug discovery - eBook eBook

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Shaping the future of lab automation through AI and robotics

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