Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Targeting SARS-CoV-2 M protein may help ease severity of COVID-19

A new study, published on the medRxiv preprint server, focused on the production of human CD4+ T cell lines (TCLs), reactive to either S or M protein, and analyzed if the S and M structural proteins had intrinsic differences in driving antigen-specific CD4+ T cell responses.

27 Jan 2022

Omicron RBD mutations increase ACE2 binding and reduce antibody sensitivity

In a study conducted at the Florida International University, USA, scientists have investigated the impact of spike receptor-binding domain (RBD) mutations of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) omicron variant on its interaction with human angiotensin-converting enzyme 2 (ACE2).

26 Jan 2022

Recipients of inactivated COVID-19 vaccine (CoronaVac) can be successfully boosted with different vaccines

In the recently published study in The Lancet, first-authored by Dr. Sue Ann Costa Clemens from the University of Oxford in the United Kingdom and the University of Siena in Italy, a comprehensive analysis has been pursued on the immunogenicity and safety of both homologous and heterologous boosting after receiving the inactivated vaccine CoronaVac.

26 Jan 2022

Urinary proteomic COV50 marker accurately predicts adverse COVID-19 outcomes

The researchers described COV50, a urinary biomarker, that can predict death and disease progression in COVID-19.

26 Jan 2022

T-cell apoptosis linked to poor prognosis among COVID-19 patients

Researchers assess the probability of T-cell apoptosis in patients with severe COVID-19 who were admitted to the hospital.

26 Jan 2022

Study shows enduring T-cell immunity up to at least 1-year after SARS-CoV-2 infection

A new study assesses SARS-CoV-2 antigen-specific cytokine responses in a cohort of SARS-CoV-2 infected individuals with varying levels of disease.

26 Jan 2022

New research on SARS-CoV-2 Omicron and care home residents

Researchers find a reduced risk of hospitalizations and deaths in long term care facility residents infected with SARS-CoV-2 Omicron variant.

26 Jan 2022

Cross-recognition of SARS-CoV-2 vaccine-elicited T cell responses among different variants

In a new study, researchers evaluated SARS-CoV-2 vaccination-induced T cell responses cross-recognition among the early and novel SARS-CoV-2 variants.

26 Jan 2022

Antibodies against SARS-CoV-2 found to persist for up to 15 months after infection

In a new study, a team of researchers explored the association between total immunoglobulin (IgM, IgA, and IgG) against SARS-CoV-2 and protective immunity.

26 Jan 2022

Study suggests synthetic SARS-CoV-2 S glycoprotein coated lipid vesicles are an effective vaccine candidate

In a new study, a team of researchers developed a vaccine candidate with the SARS-CoV-2 spike (S) glycoprotein coated onto lipid vesicles which resembles virus-like particles.

26 Jan 2022

Alterations of sphingolipids and their metabolizing enzymes in hospitalized or convalescent COVID-19 patients

An interdisciplinary team of researchers from Europe analyzed the alterations of sphingolipids and their metabolizing enzymes in hospitalized or convalescent COVID-19 patients.

26 Jan 2022

Exploring hematological alterations in COVID-19 patients

New study findings indicated that some hematological alterations that occur during COVID-19-related hospital admission were associated with an increase in the risk of COVID-19-associated ICU admission and mortality.

26 Jan 2022

Endosomal sorting of neuropilin-1 in SARS-CoV-2 infectivity

A study recently identified Neurolipin-1 or NRP1, a host factor for SARS-CoV-2 infection, as a cargo retrograde-transported by the ESCPE-1.

26 Jan 2022

Study finds overexpression of 3 SARS-CoV-2 genes could globally compromise transcriptome of human pluripotent stem cell-derived cardiomyocytes

In a recent study, whole mRNA-seq was used to investigate the global effects of SARS-CoV-2 viral genes Nsp6, Nsp8, and M on the transcriptome of hPSC-CMs.

26 Jan 2022

The new Omicron subvariant BA.2: what we know so far

Presently, an Omicron subvariant known as BA.2, first identified in late 2021, has made headlines due to its rapid spread.

26 Jan 2022

SARS-CoV-2 Omicron variant found to display increased resilience to antiviral type I interferon response

In a new study, scientists have compared the Omicron variant with the Delta VOC (B.1.617.2) as well as the wildtype strain (B.1), with respect to their interaction with the antiviral type 1 interferon response in infected cells.

26 Jan 2022

Effects of the Omicron spike amino acid changes in the interaction with human ACE2 receptor or human antibodies

A recent study analyzed the effects of the interaction between SARS-CoV-2 Omicron spike amino acid and the human ACE2 receptor or with human antibodies.

26 Jan 2022

Anti-SARS-CoV-2 antibodies found in wild mustelids in France

A new study focused on the identification of SARS-CoV-2 infection in wild mustelids in the French region of Brittany.

26 Jan 2022

Test-negative case-control analysis during a Delta variant-dominant period in California’s prisons

A new study studies the waning of vaccine-conferred protection against SARS-CoV-2 infection, specifically the Delta variant, in two high-risk populations.

26 Jan 2022

COVID-19 vaccine does not lead to infertility in either men or women

In a recent prospective cohort study accepted to the American Journal of Epidemiology, researchers observed links between female and male coronavirus disease 2019 (COVID-19) vaccination and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and fecundability or the per-cycle likelihood of conception in North American couples seeking to conceive.

26 Jan 2022

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Targeting SARS-CoV-2 M protein may help ease severity of COVID-19

Omicron RBD mutations increase ACE2 binding and reduce antibody sensitivity

Recipients of inactivated COVID-19 vaccine (CoronaVac) can be successfully boosted with different vaccines

Urinary proteomic COV50 marker accurately predicts adverse COVID-19 outcomes

T-cell apoptosis linked to poor prognosis among COVID-19 patients

Study shows enduring T-cell immunity up to at least 1-year after SARS-CoV-2 infection

New research on SARS-CoV-2 Omicron and care home residents

Cross-recognition of SARS-CoV-2 vaccine-elicited T cell responses among different variants

Antibodies against SARS-CoV-2 found to persist for up to 15 months after infection

Study suggests synthetic SARS-CoV-2 S glycoprotein coated lipid vesicles are an effective vaccine candidate

Alterations of sphingolipids and their metabolizing enzymes in hospitalized or convalescent COVID-19 patients

Exploring hematological alterations in COVID-19 patients

Endosomal sorting of neuropilin-1 in SARS-CoV-2 infectivity

Study finds overexpression of 3 SARS-CoV-2 genes could globally compromise transcriptome of human pluripotent stem cell-derived cardiomyocytes

The new Omicron subvariant BA.2: what we know so far

SARS-CoV-2 Omicron variant found to display increased resilience to antiviral type I interferon response

Effects of the Omicron spike amino acid changes in the interaction with human ACE2 receptor or human antibodies

Anti-SARS-CoV-2 antibodies found in wild mustelids in France

Test-negative case-control analysis during a Delta variant-dominant period in California’s prisons

COVID-19 vaccine does not lead to infertility in either men or women

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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