Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

SARS-CoV-2 clade linked to disease severity in the early phase of the pandemic

A new study in the journal JAMA Network reports on the disease severity associated with some clades of the virus, from an analysis of genomes from specimens isolated in the initial phase of the pandemic.

27 Apr 2021

Israel study suggests elementary school reopenings are low-risk for COVID-19 transmission

Ever since COVID-19 first emerged with devastating ferocity, the emphasis has been on interrupting its spread until effective, safe and targeted antivirals and vaccines become available. The chief focus has been on non-pharmaceutical interventions (NPIs), including school closures, social distancing and shelter in place orders.

27 Apr 2021

Some heart medications may facilitate SARS-CoV-2 infection through increasing ACE2 receptor levels

An interesting poster, just presented at the annual meeting of the American Society for Pharmacology and Experimental Therapeutics 2021, reports an association between the use of certain heart medications and the risk of COVID-19.

27 Apr 2021

Study identifies mechanism behind SARS-CoV-2 viral protein production

A new study from German researchers examines how SARS viruses, including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), hijack cells and reprogram them to enhance viral replication.

27 Apr 2021

What is the role of nanotechnology in the current COVID-19 outbreak?

The nanotechnology-based medicine platforms against COVID-19 bears hope for relief from the pandemic to save lives and mitigate the infection as part of a broader global public health agenda.

27 Apr 2021

Nucleocapsid-based vaccines may prevent SARS-CoV-2 dissemination to distal organs

A team of scientists recently investigated and compared the efficacy of spike-based and nucleocapsid-based COVID-19 vaccines in mice infected with SARS-CoV-2. Their findings reveal that nucleocapsid-based vaccines are effective in preventing SARS-CoV-2 infection in distal organs, such as the brain.

27 Apr 2021

Researchers develop eleven SARS-CoV-2 RBD nanobodies using computational design

To develop therapeutics that block this binding process, a team of researchers recently used an integrated computational approach to design nanobodies (Nbs) against the SARS-CoV-2 RBD, using neutralizing/monoclonal antibodies specific to RBD of the spike protein.

27 Apr 2021

Triple mutation in SARS-CoV-2 seen in second wave of COVID-19 in India

Researchers sequenced the viral genome from samples in the state of Maharashtra and found a unique combination of three mutations that suggest the SARS-CoV-2 virus is continually evolving to evade the human immune response.

27 Apr 2021

Nanobodies neutralize SARS-CoV-2 in pre-clinical model

A team of Australian researchers at the Walter and Eliza Hall Institute of Medical Research (WEHI), the Doherty Institute, and the Kirby Institute have identified neutralizing nanobody cocktails that block the SARS-CoV-2 virus from entering cells in pre-clinical models.

27 Apr 2021

Research suggests that Ginkgo biloba extract contains naturally occurring inhibitors against SARS-CoV-2

Researchers at Shihezi University in China found that Gingko Biloba leaves extract contains the most potent SARS-CoV-2 3-Chymotrypsin-like protease (3CLpro). This virally encoded main proteinase is essential for viral replication in coronaviruses.

27 Apr 2021

Study reveals a hidden role of circulating microRNA as a driver of SARS-CoV-2 infection

In a methodological tour-de-force study, a large group of researchers from the USA and the United Kingdom analyzed patient transcriptomic data in-depth and discovered a circulating microRNA (miR-2392) that is directly implicated in the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) machinery during the infection process.

26 Apr 2021

Study finds no evidence to support link between ABO blood group and COVID-19 risk

Researchers from the Boston University School of Public Health in the United States say there is no evidence to support a correlation between ABO blood group and the risk of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or the severity of coronavirus disease 2019 (COVID-19).

26 Apr 2021

Prior SARS-CoV-2 infection and Pfizer-BioNTech’s COVID-19 vaccine provide similar immunity

Researchers in Israel have conducted a study showing that the immunity provided against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease (COVID-19) – is similar following natural infection or immunization with the Pfizer-BioNTech BNT162b2 vaccine.

26 Apr 2021

Study shows over 2% positivity rate for asymptomatic pediatric dental patients tested for COVID-19

A study by a University of Illinois Chicago pediatric dentist has shown a novel way to track potential COVID-19 cases -- testing children who visit the dentist. The study also showed an over 2% positivity rate for the asymptomatic children tested.

26 Apr 2021

Ultraviolet C radiation is effective in inactivating SARS-CoV-2 on glass surfaces, a study finds

A team of scientists from the Texas Biomedical Research Institute and UV Innovators, Inc., USA, recently developed an ultraviolet C radiation emitting device called NuvaWave, which is capable of inactivating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on glass surfaces within seconds.

26 Apr 2021

Researchers characterize India’s devastating second wave of COVID-19

The COVID-19 pandemic continues to take a heavy toll on human health worldwide. The second wave in India has caught everyone by surprise, showing up the total lack of foresight or precautions. With well over 0.2 million deaths in India, and infections raging out of control, a new study predicts 0.35 million daily cases at the peak of the second wave.

26 Apr 2021

SARS-CoV-2 antibody response robust in nursing home residents after Pfizer-BioNTech vaccine

However, with the waning of the immune response, it is not clear if these older people respond to the vaccine as well as younger individuals do. A recent study explored this question and found that though the antibody levels were somewhat lower in this group, they were still robust. This is a promising observation.

26 Apr 2021

Host cell transmembrane protein MARCH8 targets lysine residues to inhibit SARS-CoV-2 and other viruses

A new study deals with the inhibitory activity of a membrane protein that has broad-spectrum activity against multiple viruses, showing that this is due to its effect on cytoplasmic lysine residue incorporation into replicating virions.

26 Apr 2021

Could pooled testing really improve COVID-19 transmission management and decrease costs?

Pooled testing for SARS-CoV-2 detection is instrumental for increasing test capacity while decreasing test cost. A team of researchers at Yale School of the Environment determined the barriers to implementing pooled testing in United States laboratories. The study showed that many laboratories use many instruments in their testing procedures, varying in the number of samples each can process.

26 Apr 2021

Previous SARS-CoV-2 infection associated with more adverse events following mRNA vaccination

The phase 3 trials of the Pfizer and Moderna COVID-19 vaccines did not include those with a known previous SARS-CoV-2 infection. Recent evidence indicates that mRNA vaccines may induce more adverse events in these individuals. In a recent study, 947 individuals, 265 of which have previously reported SARS-CoV-2 infection, were monitored post-vaccination for adverse events, finding that there could be a link between previous infection and greater incidence of these events.

26 Apr 2021

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

SARS-CoV-2 clade linked to disease severity in the early phase of the pandemic

Israel study suggests elementary school reopenings are low-risk for COVID-19 transmission

Some heart medications may facilitate SARS-CoV-2 infection through increasing ACE2 receptor levels

Study identifies mechanism behind SARS-CoV-2 viral protein production

What is the role of nanotechnology in the current COVID-19 outbreak?

Nucleocapsid-based vaccines may prevent SARS-CoV-2 dissemination to distal organs

Researchers develop eleven SARS-CoV-2 RBD nanobodies using computational design

Triple mutation in SARS-CoV-2 seen in second wave of COVID-19 in India

Nanobodies neutralize SARS-CoV-2 in pre-clinical model

Research suggests that Ginkgo biloba extract contains naturally occurring inhibitors against SARS-CoV-2

Study reveals a hidden role of circulating microRNA as a driver of SARS-CoV-2 infection

Study finds no evidence to support link between ABO blood group and COVID-19 risk

Prior SARS-CoV-2 infection and Pfizer-BioNTech’s COVID-19 vaccine provide similar immunity

Study shows over 2% positivity rate for asymptomatic pediatric dental patients tested for COVID-19

Ultraviolet C radiation is effective in inactivating SARS-CoV-2 on glass surfaces, a study finds

Researchers characterize India’s devastating second wave of COVID-19

SARS-CoV-2 antibody response robust in nursing home residents after Pfizer-BioNTech vaccine

Host cell transmembrane protein MARCH8 targets lysine residues to inhibit SARS-CoV-2 and other viruses

Could pooled testing really improve COVID-19 transmission management and decrease costs?

Previous SARS-CoV-2 infection associated with more adverse events following mRNA vaccination

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

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