T Cell News and Research

Latest T Cell News and Research

Experts discuss potential of DNA origami

Ten years after its introduction, DNA origami, a fast and simple way to assemble DNA into potentially useful structures, is finally coming into its own.

7 Jul 2016

Buck researchers find new way for possible treatment of AMD

Buck researchers boosted the potency of a broccoli-related compound by ten times and identified it as a possible treatment for age-related macular degeneration (AMD), the leading cause of vision loss affecting more than 10 million older Americans.

7 Jul 2016

Minoryx Therapeutics initiates phase 1 clinical trial of MIN-102

Minoryx Therapeutics, a drug development company specialized in the discovery and development of new drugs for orphan diseases, today announces the initiation of its first-in-man Phase 1 clinical trial for its lead compound MIN-102.

7 Jul 2016

AMPK protein activated during fasting regulates hunger neurons in the brain

Neurons in the brain that control hunger are regulated by AMPK, a protein activated during fasting, report researchers from Tufts University School of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School in Neuron on July 6, 2016.

6 Jul 2016

Existing anti-inflammatory drugs may be effective in treating epilepsy

In epileptic patients, seizures lead to an increased level of inflammation-related proteins called chemokines in the brain, and systemic inflammation likely helps trigger and promote the recurrence of seizures, making inflammation a promising new target for anticonvulsant therapy.

6 Jul 2016

Liraglutide drug lowers blood sugar levels in diabetic patients taking large doses of insulin

When Amy Sweat was 19 years old, while she was in the hospital recovering from surgery, she was diagnosed with Type 2 diabetes. Ms. Sweat was treated for her diabetes, first on oral drugs, then on increasingly larger doses of insulin, but the years went by and she never was able to achieve good blood sugar control.

6 Jul 2016

Whole-genome omics data can improve accuracy of breast cancer survival predictions

Precise predictions of whether a tumor is likely to spread would help clinicians and patients choose the best course of treatment. But current methods fall short of the precision needed.

6 Jul 2016

Researchers use FRET to make activation of AMPA receptors optically visible

Our brain is a high-performance computer. One of the key players in this complex system is the AMPA-type glutamate receptor. It ensures that neurotransmission proceeds at a breakneck pace from cell to cell.

6 Jul 2016

New research reveals b1-integrin protein as promising therapeutic target for muscle aging

As we age, the function and regenerative abilities of skeletal muscles deteriorate, which means it is difficult for the elderly to recover from injury or surgery. New work from Carnegie's Michelle Rozo, Liangji Li, and Chen-Ming Fan demonstrates that a protein called b1-integrin is crucial for muscle regeneration.

6 Jul 2016

Scientists discover X-chromosome-inherited type of osteogenesis imperfecta

Researchers from the University of Zurich and University Children's Hospital Zurich have discovered the first X-chromosome-inherited type of the congenital disease osteogenesis imperfecta, also known as brittle-bone disease.

6 Jul 2016

New lung-targeted gene therapy shows promise in improving treatment for emphysema

Researchers have developed a new strategy using lung-targeted gene therapy that may lead to improved treatments for inherited diseases including emphysema.

6 Jul 2016

Computational modelling method can predict development and progression of osteoarthritis

Computational modelling makes it possible to predict the onset and progression of knee osteoarthritis in overweight people, shows a new study from the University of Eastern Finland.

6 Jul 2016

Researchers find distinct, non-identical differences among retroviruses

In the most comprehensive study of its kind, researchers in the report that most types of retroviruses have distinct, non-identical virus structures.

6 Jul 2016

Tiny micro-vesicle structures may help predict probability of developing Alzheimer's dementia

Researchers at University of California San Diego School of Medicine say tiny micro-vesicle structures used by neurons and other cells to transport materials internally or dispose of them externally carry tell-tale proteins that may help to predict the likelihood of mild cognitive impairment (MCI) developing into full-blown Alzheimer's disease (AD).

6 Jul 2016

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

Amgen has announced that the European Commission (EC) has approved a variation to the marketing authorization for Kyprolis® (carfilzomib) to include use in combination with dexamethasone alone for adult patients with multiple myeloma who have received at least one prior therapy. The extended indication marks the second approval for Kyprolis by the EC in less than a year.

6 Jul 2016

Researchers identify astroglia-mediated mechanism for causing FXS symptoms in mice

A study published today in the Journal of Neuroscience led by Yongjie Yang of Tufts University School of Medicine identifies an astroglial trigger mechanism as contributing to symptoms of fragile X syndrome in mice.

6 Jul 2016

Alnylam reports new results from investigational RNAi therapeutic programs

Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, announced today preliminary results from its ongoing Phase 2 open-label extension (OLE) studies with patisiran and revusiran, both investigational RNAi therapeutics targeting transthyretin (TTR) for the treatment of hereditary TTR-mediated amyloidosis (hATTR amyloidosis).

6 Jul 2016

Mice study shows how multiple malaria infections lead to increased health risks

Scientists have discovered why infections with two types of malaria parasite lead to greater health risks - because one species helps the other to thrive.

6 Jul 2016

Researchers demonstrate simple approach to prove how classes of new drugs work

A collaborative effort by cancer researchers at Cold Spring Harbor Laboratory and chemists at Boehringer Ingelheim, a pharmaceutical firm, has resulted in the identification of a new drug target in leukemia and creation of a candidate drug that hits the target.

6 Jul 2016

Necitumumab drug shows minor added benefit in patients with metastatic NSCLC

The monoclonal antibody necitumumab has been approved since February 2016 for the treatment of patients with locally advanced or metastatic epidermal growth factor receptor (EGFR) expressing non-small cell lung cancer (NSCLC) who have not received prior chemotherapy for this condition.

5 Jul 2016

T Cell News and Research

Latest T Cell News and Research

Experts discuss potential of DNA origami

Buck researchers find new way for possible treatment of AMD

Minoryx Therapeutics initiates phase 1 clinical trial of MIN-102

AMPK protein activated during fasting regulates hunger neurons in the brain

Existing anti-inflammatory drugs may be effective in treating epilepsy

Liraglutide drug lowers blood sugar levels in diabetic patients taking large doses of insulin

Whole-genome omics data can improve accuracy of breast cancer survival predictions

Researchers use FRET to make activation of AMPA receptors optically visible

New research reveals b1-integrin protein as promising therapeutic target for muscle aging

Scientists discover X-chromosome-inherited type of osteogenesis imperfecta

New lung-targeted gene therapy shows promise in improving treatment for emphysema

Computational modelling method can predict development and progression of osteoarthritis

Researchers find distinct, non-identical differences among retroviruses

Tiny micro-vesicle structures may help predict probability of developing Alzheimer's dementia

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

Researchers identify astroglia-mediated mechanism for causing FXS symptoms in mice

Alnylam reports new results from investigational RNAi therapeutic programs

Mice study shows how multiple malaria infections lead to increased health risks

Researchers demonstrate simple approach to prove how classes of new drugs work

Necitumumab drug shows minor added benefit in patients with metastatic NSCLC

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Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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T Cell News and Research

Latest T Cell News and Research

Immunology eBook

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

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