T Cell News and Research

Latest T Cell News and Research

Scientists streamline total synthesis of uncialamycin drug

A team led by Rice University scientists has improved the production of a potent anti-tumor antibiotic known as uncialamycin.

23 Jun 2016

Lack of Alix protein leads to occurrence of hydrocephalus in the brain

A team led by researchers at St. Jude Children's Research Hospital report that mice lacking the protein Alix develop hydrocephalus or "water on the brain." Alix ensures that epithelial cells of the choroid plexus are oriented correctly with respect to one another to prevent compromise of the epithelial barrier.

23 Jun 2016

MAIT cells of immune system can fight all sorts of bacterial and viral infections

Oxford University research has found that a little-studied and relatively unknown part of the human immune system could be twice as important as previously thought.

23 Jun 2016

Novel stem cell-containing bio-ink allows 3D printing of complex tissues for surgical implants

Scientists at the University of Bristol have developed a new kind of bio-ink, which could eventually allow the production of complex tissues for surgical implants.

23 Jun 2016

Long-term suppression of neurotransmitter acetylcholine may lead to dementia-like changes in the brain

A new study from Western University is helping to explain why the long-term use of common anticholinergic drugs used to treat conditions like allergies and overactive bladder lead to an increased risk of developing dementia later in life.

23 Jun 2016

Scientists discover RNA methylation could strengthen memory formation

New insight into the process that converts experiences into stable long-term memories has been uncovered by neurobiologists from the University of California, Irvine and the University of Queensland.

23 Jun 2016

Researchers uncover new clues about role of glucosamine in early embryonic development

Most pregnant women with well-controlled diabetes give birth to healthy children. But their babies run much higher risks of birth defects than babies born to women without diabetes, because very early in embryonic development, the babies are exposed to higher levels of glucose in maternal blood.

23 Jun 2016

Researchers discover how West Nile virus survivors often develop memory loss

Researchers at the University of Colorado Anschutz Medical Campus have discovered how the most severe forms of West Nile virus cause memory loss and mood disorders, opening the door to potential new treatments for the mosquito-borne illness.

23 Jun 2016

Novel combination therapy slows cancer growth in patients with advanced solid tumors

A phase 1 clinical trial testing a novel combination therapy developed by scientists at VCU Massey Cancer Center slowed the growth of cancer in the majority of trial participants, which were patients with advanced solid tumors.

22 Jun 2016

Researchers reveal novel mechanism of smoke induced collapse of protein homeostasis in COPD

Few threats to public health are as perilous as cigarette smoking, with more than 435,000 Americans dying each year of tobacco-related pulmonary illnesses such as chronic obstructive pulmonary disease (COPD).

22 Jun 2016

Metal ions released by implant wear can damage progenitors of bone-forming cells

In metal-on-metal pairings, both the shell and head of an implant consist of a cobalt-chromium-molybdenum alloy. The release of metal ions into the body has been reported as a result of implant wear. Bone loss (osteolysis) was observed in many cases.

22 Jun 2016

Hops show promise in reducing breast cancer risk

Hops, the flower cones used in beer-making, are also found in dietary supplements designed to help treat post-menopausal symptoms and other conditions. Scientists are now investigating whether an extract from the plant could also help fend off breast cancer.

22 Jun 2016

Researchers reveal DNA unwrapping can happen asymmetrically to expose specific genes

The protein complex that holds strands of DNA in compact spools partially disassembles itself to help genes reveal themselves to specialized proteins and enzymes for activation, according to Rice University researchers and their colleagues.

22 Jun 2016

New study suggests how rod photoreceptors may have originated to give rise to nocturnal mammals

Retinas from our earliest vertebrate ancestors had cone-like photoreceptors, presumably allowing them to see in daylight, but little ability to see at night. Then, millions of years ago in the Mesozoic era, and in relatively short order, mammals emerged that had retinas with predominantly rod photoreceptors, allowing for them to see at night perhaps to hunt for food while their dinosaur predators were dozing.

22 Jun 2016

Salvage inotuzumab ozogamicin improves ALL outcomes

Compared with standard chemotherapy, treatment with inotuzumab ozogamicin increases the rate of complete remission and allows a higher proportion of patients with relapsed or refractory acute lymphoblastic leukaemia to subsequently receive stem-cell transplantation, research suggests.

22 Jun 2016

Moffitt researchers develop mathematical model to show differences in subpopulations of tumors

Tumors are composed of many subpopulations of cells. A general consensus among scientists is that these subpopulations are due to random mutations. However, Moffitt Cancer Center researchers found that these assumptions may be incorrect.

22 Jun 2016

First CRISPR/Cas9 screen helps identify human proteins required for Zika virus replication

Scientists at the University of Massachusetts Medical School have performed the first CRISPR/Cas9 screen to discover human proteins that Zika virus needs for replication.

22 Jun 2016

SORLA protein makes fat cells oversensitive to insulin

SORLA is a protein that influences the balance of metabolic processes in adipose tissue, a particular form of fat. Too much of it makes fat cells overly sensitive to insulin, which leads them to break down less fat. SORLA was previously known for its protective role in Alzheimer's disease.

22 Jun 2016

Drexel University researchers aim to identify new molecular mechanisms involved in chronic pain

Chronic pain is one of the most prevalent, disabling and expensive public health crises in the United States. It affects more than 100 million Americans, with annual costs estimated at $635 billion, says a 2014 report from the American Pain Society.

22 Jun 2016

New CAR-based therapy using combined cancer target could be effective for solid tumors

Chimeric antigen receptors (CARs), engineered from a patient's own immune cells, have been successful for treating blood cancers, but using CARs for solid tumors has been limited by side effects to normal tissues containing the protein targeted by the engineered cells.

22 Jun 2016

T Cell News and Research

Latest T Cell News and Research

Scientists streamline total synthesis of uncialamycin drug

Lack of Alix protein leads to occurrence of hydrocephalus in the brain

MAIT cells of immune system can fight all sorts of bacterial and viral infections

Novel stem cell-containing bio-ink allows 3D printing of complex tissues for surgical implants

Long-term suppression of neurotransmitter acetylcholine may lead to dementia-like changes in the brain

Scientists discover RNA methylation could strengthen memory formation

Researchers uncover new clues about role of glucosamine in early embryonic development

Researchers discover how West Nile virus survivors often develop memory loss

Novel combination therapy slows cancer growth in patients with advanced solid tumors

Researchers reveal novel mechanism of smoke induced collapse of protein homeostasis in COPD

Metal ions released by implant wear can damage progenitors of bone-forming cells

Hops show promise in reducing breast cancer risk

Researchers reveal DNA unwrapping can happen asymmetrically to expose specific genes

New study suggests how rod photoreceptors may have originated to give rise to nocturnal mammals

Salvage inotuzumab ozogamicin improves ALL outcomes

Moffitt researchers develop mathematical model to show differences in subpopulations of tumors

First CRISPR/Cas9 screen helps identify human proteins required for Zika virus replication

SORLA protein makes fat cells oversensitive to insulin

Drexel University researchers aim to identify new molecular mechanisms involved in chronic pain

New CAR-based therapy using combined cancer target could be effective for solid tumors

Immunology eBook

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

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