T Cell News and Research

Latest T Cell News and Research

Study shows inhibition of SHP-2 enzyme can diminish lupus symptoms

Researchers at Beth Israel Deaconess Medical Center have identified an enzyme that is significantly elevated in mouse models of systemic lupus erythematosus and in blood samples of patients with lupus.

17 May 2016

FDA approves additional indication for Eisai's anticancer agent Lenvima in combo with Everolimus for advanced renal cell carcinoma

Eisai Co., Ltd. has announced that its U.S. subsidiary Eisai Inc. has received approval from the U.S. Food and Drug Administration (FDA) for an additional indication for Eisai's in-house developed novel anticancer agent Lenvima (lenvatinib mesylate) in combination with everolimus for the treatment of patients with advanced renal cell carcinoma following one prior anti-angiogenic therapy.

16 May 2016

American Thoracic Society and Sunovion release landmark survey of pulmonologists’ attitudes and practices with inhalation devices for COPD

The American Thoracic Society (ATS) and Sunovion Pharmaceuticals Inc. (Sunovion) today announced the results of a survey of pulmonologists and pulmonology fellows to determine physicians’ knowledge, attitudes, and practices related to chronic obstructive pulmonary disease (COPD) management, with particular attention to the use of hand-held small volume nebulizers. A small volume nebulizer is a device powered by air that aerosolizes medications for delivery to patients.

16 May 2016

Ipsen partners with IMCB to advance understanding and research of Botulinum Neurotoxin Biology

Ipsen S.A., a global specialty-driven pharmaceutical company, and the Institute of Molecular and Cell Biology (IMCB), a research institute under the aegis of the Agency for Science, Technology and Research (A*STAR), Singapore, today announced the signature of a research partnership to study the intracellular trafficking of botulinum neurotoxins (BoNTs) within neurons.

16 May 2016

Pluristem completes enrollment in Phase II intermittent claudication trial

Pluristem Therapeutics Inc., a leading developer of placenta-based cell therapy products, today announced it has completed the planned enrollment of 150 patients in a global Phase II trial of its PLacental eXpanded (PLX)-PAD cells for the treatment of intermittent claudication (IC), a peripheral artery disease (PAD). The double blind, randomized, placebo controlled trial enrolled 50 patients since October 2015 in the U.S., Germany, Israel, and South Korea.

16 May 2016

Unlocking the dark proteome: an interview with Dr Kriwacki

The term dark proteome refers to proteins whose structural features and thus functions are not well understood. Many proteins within the dark proteome do not fold into stable three-dimensional structures. These proteins are called intrinsically disordered proteins (IDPs) and feature highly flexible, disordered confirmations.

16 May 2016

Genomic cfDNA profiling feasible in metastatic CRPC

Comprehensive genomic profiling of cell-free DNA can provide clinically useful information in men with castration-resistant prostate cancer treated with enzalutamide, research indicates.

14 May 2016

TSRI chemists identify and design potent therapeutic ‘warheads’ for different diseases

In a pair of related studies, chemists from the Florida campus of The Scripps Research Institute (TSRI) have identified and designed dozens of molecular “warheads” that not only can detect a key biomarker of cancer, but also could be developed into a potent new class of drug candidates for a range of diseases.

13 May 2016

Researchers identify out of control immune system linked to neurodegenerative diseases

AN out of control immune system has been identified as a possible cause of neurodegenerative diseases such as Alzheimer’s.

13 May 2016

BioNano study describes use of Irys System with Illumina-based NGS methods to achieve high-quality genomic assemblies

BioNano Genomics, the leader in physical genome mapping, today announced publication of another study describing application of its next-generation mapping (NGM) technology as the critical component in achieving high-quality de novo human genome assemblies with unprecedented contiguity.

13 May 2016

ISSCR releases updated guidelines for stem cell research, development of new therapies

The International Society for Stem Cell Research, the world's largest professional organization of stem cell scientists, today released newly updated guidelines for stem cell research and the development of new clinical therapies.

13 May 2016

Sleep hormone melatonin may be responsible for type 2 diabetes risk among overnight workers

A new experimental and clinical study from Lund University in Sweden shows that the sleep hormone melatonin impairs insulin secretion in people with a common gene variant.

13 May 2016

CTD helps scientists explore impact of environmental exposures on human health

Two new studies from a group at North Carolina State University give researchers new strategies for connecting environmental exposures to human health effects.

13 May 2016

Inhibiting autophagy can effectively block tumor cell migration, breast cancer metastasis

Researchers from the University of Chicago have shown that inhibiting autophagy, a self-devouring process used by cells to degrade large intra-cellular cargo, effectively blocks tumor cell migration and breast cancer metastasis in tumor models.

13 May 2016

Genetic change to non-DNA structures in cell can cause cancer

A mutation that affects the proteins that package DNA--without changing the DNA itself--can cause a rare form of cancer, according to new findings in this week's Science from researchers at The Rockefeller University.

13 May 2016

New way of understanding neurodegeneration may lead to novel treatments

University of Adelaide researchers have developed a new theory for the causes of dementia and other neurodegenerative diseases, involving an out-of-control immune system.

13 May 2016

Gene therapy shows promise in treating glioblastoma

A team from the International School for Advanced Studies in Trieste has obtained very promising results by applying gene therapy to glioblastoma.

13 May 2016

Histone mutation linked to fatal pediatric brain tumor

A single defect in a gene that codes for a histone — a "spool" that wraps idle DNA — is linked to pediatric cancers in a study published today in the journal Science.

13 May 2016

McGill researchers discover brain cells that play key role in leptin sensing, weight gain

It's rare for scientists to get what they describe as "clean" results without spending a lot of time repeating the same experiment over and over again. But when researchers saw the mice they were working with doubling their weight within a month or two, they knew they were on to something.

13 May 2016

Drug-repositioning strategy could help combat Chikungunya virus

Since 2013, the mosquito-borne Chikungunya virus has spread rapidly through South America and the Caribbean, and is now threatening Southern Europe and the southern US.

13 May 2016

T Cell News and Research

Latest T Cell News and Research

Study shows inhibition of SHP-2 enzyme can diminish lupus symptoms

FDA approves additional indication for Eisai's anticancer agent Lenvima in combo with Everolimus for advanced renal cell carcinoma

American Thoracic Society and Sunovion release landmark survey of pulmonologists’ attitudes and practices with inhalation devices for COPD

Ipsen partners with IMCB to advance understanding and research of Botulinum Neurotoxin Biology

Pluristem completes enrollment in Phase II intermittent claudication trial

Unlocking the dark proteome: an interview with Dr Kriwacki

Genomic cfDNA profiling feasible in metastatic CRPC

TSRI chemists identify and design potent therapeutic ‘warheads’ for different diseases

Researchers identify out of control immune system linked to neurodegenerative diseases

BioNano study describes use of Irys System with Illumina-based NGS methods to achieve high-quality genomic assemblies

ISSCR releases updated guidelines for stem cell research, development of new therapies

Sleep hormone melatonin may be responsible for type 2 diabetes risk among overnight workers

CTD helps scientists explore impact of environmental exposures on human health

Inhibiting autophagy can effectively block tumor cell migration, breast cancer metastasis

Genetic change to non-DNA structures in cell can cause cancer

New way of understanding neurodegeneration may lead to novel treatments

Gene therapy shows promise in treating glioblastoma

Histone mutation linked to fatal pediatric brain tumor

McGill researchers discover brain cells that play key role in leptin sensing, weight gain

Drug-repositioning strategy could help combat Chikungunya virus

Immunology eBook

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

Newsletters you may be interested in