T Cell News and Research

Latest T Cell News and Research

BioTek to present new technologies for cell-based applications at analytica 2016

BioTek will present two opportunities for researchers to learn about new instruments and approaches to simplify their workflow at analytica 2016, the 25th International Trade Fair for Laboratory Technology, Analysis, Biotechnology and analytica conference.

5 May 2016

Blend of pulverized natural bone and man-made plastic can create 3D printed replacement bones

To make a good framework for filling in missing bone, mix at least 30 percent pulverized natural bone with some special man-made plastic and create the needed shape with a 3-D printer. That's the recipe for success reported by researchers at The Johns Hopkins University in a paper published April 18 online in ACS Biomaterials Science & Engineering.

5 May 2016

Research provides new insight into cellular composition of IDH1-mutant gliomas

Winner of the Preuss Research Award, Andrew Venteicher, MD, PhD, presented his research, Cellular Architecture of Human IDH1-mutant Gliomas Revealed Using Single-cell RNA Sequencing, during the 2016 American Association of Neurological Surgeons Annual Scientific Meeting.

5 May 2016

Bayer-new phase 3 liver cancer data

Bayer has announced that a Phase III trial evaluating its oncology compound Stivarga® (regorafenib) tablets for the treatment of patients with unresectable hepatocellular carcinoma (HCC) has met its primary endpoint of a statistically significant improvement in overall survival. The study, called RESORCE, evaluated the efficacy and safety of regorafenib in patients with HCC whose disease has progressed after treatment with sorafenib. The safety and tolerability were generally consistent with the known profile of regorafenib. Detailed efficacy and safety analyses from this study are expected to be presented at an upcoming scientific congress.

4 May 2016

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

University of Alabama at Birmingham researchers report the first documentation that suppressing a key cell-signaling pathway in a rat model of Parkinson's disease reduces pathogenesis. Oral administration of AZD1480 — one of the JAK/STAT pathway inhibitors generally known as Jakinibs — lessened the destructive inflammation and nerve cell degradation in the area of the brain affected by Parkinson's.

4 May 2016

Scientists find that disruption to SCN rhythms can negatively impact overall health

Researchers have shown for the first time how neurons in the SCN are connected to each other, shedding light on this vital area of the brain. Understanding this structure — and how it responds to disruption — is important for tackling illnesses like diabetes and posttraumatic stress disorder. The scientists have also found that disruption to these rhythms such as shifts in work schedules or blue light exposure at night can negatively impact overall health.

4 May 2016

Real risk of rebound syndrome following fingolimod cessation for MS

Rebound syndrome following cessation of fingolimod for multiple sclerosis occurs at a clinically relevant rate, shows research, prompting the need for further study on how best to sequence and discontinue such drugs.

4 May 2016

Researchers discover critical new mechanism for genesis of heart failure

A weak heart is unable to pump an adequate amount of blood around the body. In Germany, this condition is now the commonest reason for patients to be admitted to hospital.

4 May 2016

Study reveals new cell-signaling pathway that detects chromosome missegregation

A recent research study at The Hormel Institute, University of Minnesota is providing insight into the regulation of chromosome segregation and the mechanisms used by cells to prevent them from forming tumors.

4 May 2016

Researchers safely transplant stem cells from patient's skin to the eye to restore vision

Researchers have safely transplanted stem cells derived from a patient's skin to the back of the eye in an effort to restore vision. The research is being presented at the 2016 Annual Meeting of the Association for Research in Vision and Ophthalmology this week in Seattle, Wash.

4 May 2016

New study links cathepsin S protein to tear secretion in Sjogren's syndrome patients

The autoimmune disorder Sjogren's syndrome is often overlooked or misdiagnosed because the symptoms are similar to other conditions. Its characteristic symptoms are dry eyes and dry mouth, and reduced tear production is used as part of the diagnosis.

4 May 2016

Controlling cholesterol metabolism could help reduce pancreatic cancer spread

Researchers have shown how controlling cholesterol metabolism in pancreatic cancer cells reduces metastasis, pointing to a potential new treatment using drugs previously developed for atherosclerosis.

4 May 2016

New EU project aims to develop models that can help predict behavior of cancer-related signaling pathways

A group of scientists at Helmholtz Zentrum München will engage in a new project promoted by the EU. The scientists in the team of Dr. Jan Hasenauer, head of the young investigator group 'Data-driven Computational Modeling' work as part of CanPathPro.

4 May 2016

Researchers identify 43 specific genes associated with both autism and cancer

Autism and cancer share more than 40 risk genes, suggesting that common mechanisms underlying the functions of some of these genes could conceivably be leveraged to develop therapies not just for cancer but for autism as well, an extensive assessment by researchers with the UC Davis MIND Institute and Comprehensive Cancer Center has found.

4 May 2016

Study shows syringe-like device acts as traffic cop directing bacteria to carry out infection

A study has found that a syringe-like device used to invade intestinal cells also acts as a traffic cop -- directing bacteria where to go and thereby enabling them to efficiently carry out infection.

4 May 2016

Biomedical researcher wins 2016 Gutenberg Research Award for work on programmed cell death

The Gutenberg Research College of Johannes Gutenberg University Mainz has chosen to give the 2016 Gutenberg Research Award to American biomedical researcher Dr. Vishva Dixit for his groundbreaking work in the field of programmed cell death.

4 May 2016

NSCLC MAGE-A3 immunotherapy development halted

Disease-free survival is not prolonged with adjuvant MAGE-A3 immunotherapy in patients with surgically resected non-small-cell lung cancer, according to a placebo-controlled trial.

4 May 2016

Understanding effects of freeze-thawing, intravenous delivery on MSC function

Before the therapeutic potential of using human tissue-derived mesenchymal stromal cells (MSC) to treat immune and degenerative diseases can be fully determined, the effects of freeze-thawing and intravenous delivery on MSC function must be understood.

3 May 2016

New investigational inhibitor JQEZ5 can block specific molecular malfunctions driving cancer

In a step forward in the push for targeted treatments that can block the specific molecular malfunctions driving cancer, University of North Carolina Lineberger Comprehensive Cancer Center researchers have demonstrated how a genetic mutation can drive the most common type of lymphoma as well as melanoma, the deadliest form of skin cancer.

3 May 2016

Combination of existing chemotherapy drugs can reduce breast cancer stem cells, improve survival

Two existing chemotherapy drugs appear to be a powerful pair in targeting errant stem cells that are making breast cancer and enabling its spread and recurrence, scientists report.

3 May 2016

T Cell News and Research

Latest T Cell News and Research

BioTek to present new technologies for cell-based applications at analytica 2016

Blend of pulverized natural bone and man-made plastic can create 3D printed replacement bones

Research provides new insight into cellular composition of IDH1-mutant gliomas

Bayer-new phase 3 liver cancer data

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

Scientists find that disruption to SCN rhythms can negatively impact overall health

Real risk of rebound syndrome following fingolimod cessation for MS

Researchers discover critical new mechanism for genesis of heart failure

Study reveals new cell-signaling pathway that detects chromosome missegregation

Researchers safely transplant stem cells from patient's skin to the eye to restore vision

New study links cathepsin S protein to tear secretion in Sjogren's syndrome patients

Controlling cholesterol metabolism could help reduce pancreatic cancer spread

New EU project aims to develop models that can help predict behavior of cancer-related signaling pathways

Researchers identify 43 specific genes associated with both autism and cancer

Study shows syringe-like device acts as traffic cop directing bacteria to carry out infection

Biomedical researcher wins 2016 Gutenberg Research Award for work on programmed cell death

NSCLC MAGE-A3 immunotherapy development halted

Understanding effects of freeze-thawing, intravenous delivery on MSC function

New investigational inhibitor JQEZ5 can block specific molecular malfunctions driving cancer

Combination of existing chemotherapy drugs can reduce breast cancer stem cells, improve survival

Immunology eBook

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

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