T Cell News and Research

Latest T Cell News and Research

Targeting invasive cells could be a new strategy to treat metastatic cancer, say Stony Brook researchers

Most cancer drugs are designed to target dividing cells, but a new study by Stony Brook University researchers suggests that targeting invasive cells may be a new strategy to treat metastatic cancer.

27 Oct 2015

Discovery may open new doors to understanding how melanoma grows and spreads

Of the hundreds of genes that can be mutated in a single case of melanoma, only a handful may be true "drivers" of cancer. In research that recently appeared in Nature Genetics, a Weizmann Institute of Science team has now revealed one of the drivers of a particularly deadly subset of melanomas that is seeing a rise in new cases.

27 Oct 2015

U-M study suggests new therapeutic strategy for treating Duchene muscular dystrophy

Every heart beat and step in our daily lives is dependent on the integrity of muscles and the proteins that keep them strong and free of injury as they contract and relax.

27 Oct 2015

Four microRNAs appear to play critical roles in controlling cholesterol, triglyceride metabolism

Four tiny segments of RNA appear to play critical roles in controlling cholesterol and triglyceride metabolism. In their report receiving advance online publication in Nature Medicine, a Massachusetts General Hospital-based research team describes finding how these microRNAs could reduce the expression of proteins playing key roles in the generation of beneficial HDL cholesterol, the disposal of artery-clogging LDL cholesterol, control of triglyceride levels and other risk factors of cardiovascular disease.

27 Oct 2015

Researchers develop multiplexed screening approach to study cancer development in mice

In a novel use of the CRISPR/Cas9 system, which can be deployed to switch genes off, researchers from Germany, the UK and Spain have developed a multiplexed screening approach to study and model cancer development in mice. The scientists mutated genes in the adult mouse liver uncovering their cancer-causing roles and determining which combinations of genes cooperate to cause liver cancer.

27 Oct 2015

Unique, tiny protein cage developed to deliver chemotherapy chemicals directly to cancer cells

Washington State University researchers have developed a unique, tiny protein cage to deliver nasty chemotherapy chemicals directly to cancer cells. Direct delivery could improve treatment and lessen what can be horrendous side effects from toxic drugs.

27 Oct 2015

MGH researchers identify mechanism behind the spread of neurofibrillary tangles

Massachusetts General Hospital investigators have discovered a mechanism behind the spread of neurofibrillary tangles - one of the two hallmarks of Alzheimer's disease - through the brains of affected individuals.

27 Oct 2015

UTMB researchers find mechanisms to determine when pregnant women go into labor

During the last few weeks of a woman's pregnancy, many keep an overnight bag ready to go at a moment's notice in case they begin to go into labor. They do this because there is no clear signal that labor is about to begin - before the body makes it abundantly clear that this process has started. Understanding the mechanisms that initiate this process is especially important when treating women at risk of going into labor early.

27 Oct 2015

New article reviews latest advances in magnetic particle tracking in cell therapy

A new article published in Regenerative Medicine reviews the latest advances in magnetic particle tracking in cell therapy, a potentially groundbreaking strategy in disease treatment and regenerative medicine.

27 Oct 2015

New drug combination may be effective against malignant melanoma

A team of Massachusetts General Hospital investigators has discovered a new combination of drugs that may be effective against one of the deadliest cancers, malignant melanoma. The combination - pairing a drug targeted against mutations in the BRAF gene with a second drug that targets another important signaling pathway - was discovered through one of the largest screens of cancer drug combinations conducted to date.

27 Oct 2015

Ipsen, EpiVax partner to create next generation botulinum neurotoxin and TSI therapeutics

Ipsen and the US company EpiVax, Inc. today announced that they have completed a collaborative project that provides a novel approach for creating next generation botulinum neurotoxin (BoNT) and Targeted Secretion Inhibitor (TSI) therapeutics.

27 Oct 2015

Patients with treatment-resistant autoimmune blood conditions may benefit from sirolimus

The immunosuppressant sirolimus is an effective and safe steroid-sparing therapy for children and young adults with highly treatment-resistant autoimmune blood conditions, according to a study published online today in Blood, the Journal of the American Society of Hematology.

27 Oct 2015

New fluorescent dye could serve as powerful tool to visualize biological events in living cells

A new photostable fluorescent dye for super resolution microscopy could serve as a powerful tool to visualize biological events and structural details in living cells at real-time for prolonged recording periods.

27 Oct 2015

DNA testing for Down's syndrome could potentially save lives of unborn babies

Offering pregnant women a DNA test for Down's syndrome on the NHS would reduce the dependency on invasive tests and potentially save the lives of unborn babies, a study shows.

27 Oct 2015

Mast Therapeutics begins vepoloxamer Phase 2 study in patients with chronic heart failure

Mast Therapeutics, Inc., a clinical-stage biopharmaceutical company leveraging its molecular adhesion and sealant technology (MAST) platform to develop novel therapies for sickle cell disease, heart failure, and stroke, announced that it has initiated its Phase 2 study of vepoloxamer for the treatment of patients with chronic heart failure.

26 Oct 2015

Sinovac Dalian receives approval to start human clinical trials of varicella vaccine candidate

Sinovac Biotech Ltd., a leading provider of biopharmaceutical products in China, today announced that one of its subsidiaries, Sinovac Dalian, has received approval to begin human clinical trials on its varicella vaccine candidate. The clinical trial application for the varicella vaccine was officially accepted by the China Food and Drug Administration in January 2013.

26 Oct 2015

T Cell News and Research

Latest T Cell News and Research

Targeting invasive cells could be a new strategy to treat metastatic cancer, say Stony Brook researchers

Discovery may open new doors to understanding how melanoma grows and spreads

U-M study suggests new therapeutic strategy for treating Duchene muscular dystrophy

Four microRNAs appear to play critical roles in controlling cholesterol, triglyceride metabolism

Researchers develop multiplexed screening approach to study cancer development in mice

Unique, tiny protein cage developed to deliver chemotherapy chemicals directly to cancer cells

MGH researchers identify mechanism behind the spread of neurofibrillary tangles

UTMB researchers find mechanisms to determine when pregnant women go into labor

New article reviews latest advances in magnetic particle tracking in cell therapy

New drug combination may be effective against malignant melanoma

Ipsen, EpiVax partner to create next generation botulinum neurotoxin and TSI therapeutics

Patients with treatment-resistant autoimmune blood conditions may benefit from sirolimus

New fluorescent dye could serve as powerful tool to visualize biological events in living cells

DNA testing for Down's syndrome could potentially save lives of unborn babies

Mast Therapeutics begins vepoloxamer Phase 2 study in patients with chronic heart failure

Sinovac Dalian receives approval to start human clinical trials of varicella vaccine candidate

Scalable production of gene therapy vectors: an interview with Frank Ubags

New approaches to treating lung cancer patients in New Mexico

UW researchers develop new model to more accurately predict harmful genetic mutations

Novel method for examining small molecules may provide platform for new drug design

Immunology eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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