T Cell News and Research

Latest T Cell News and Research

Lonza, Benitec partner to develop scalable manufacturing process for AAV-based viral gene therapies

Lonza Houston, Inc., a global leader in biological, cell and viral gene therapy manufacturing, and Benitec Biopharma, a clinical stage biotechnology company commercializing a patented gene-silencing technology, DNA-directed RNA interference (ddRNAi), today announced that they have entered into a Manufacturing Services Agreement to develop a scalable manufacturing process for Benitec's ddRNAi-based, Adeno-Associated Virus (AAV)-delivered products intended for therapeutic use in humans.

7 Oct 2015

SCT, Thermo Fisher Scientific collaborate to advance development of cardiac disease models

Stem Cell Theranostics announced today that they have successfully completed a research collaboration with Thermo Fisher Scientific focused on advancing the development of cardiac disease models derived from induced pluripotent stem cells using Thermo Fisher Scientific's suite of work flow reagents and SCT's patient biobank and proprietary disease modeling methods.

7 Oct 2015

Penn Medicine announces $375,000 in new grants to support BRCA-focused research projects

Penn Medicine's Basser Center for BRCA announced $375,000 in new grant funding to support BRCA-focused research projects across the nation. The grants are aimed at advancing the care of patients living with BRCA1 and BRCA2 mutations.

7 Oct 2015

Scientists awarded £417,000 to develop a gel to advance breast cancer research, reduce animal testing

Scientists at the Universities of Manchester and Nottingham have been funded to develop a gel that will match many of the biological structures of human breast tissue, to advance cancer research and reduce animal testing.

7 Oct 2015

Researchers describe unknown mechanism behind progeria

Progeria, a premature aging disease, is the research focus of Roland Foisner's team at the Max F. Perutz Laboratories of the University of Vienna and the Medical University of Vienna. Children suffering from progeria die at an average age of 14 to 15 years, often from heart attacks and strokes.

7 Oct 2015

New book highlights sophisticated neurogenic processes in adult mammalian brain

In discrete locations of the adult brain, new neurons are born from stem cells that differentiate, migrate, and integrate into the existing neural network. This process is implicated in normal brain functions such as memory formation and is disrupted in many disease states, including Alzheimer's, schizophrenia, and depression.

7 Oct 2015

New studies suggest ways to improve cancer care by inhibiting oncogenes, boosting tumor-suppressor activity

Two new studies by cancer scientists at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) suggest new approaches for treating cancer by inhibiting overactive cancer-promoting genes and by enhancing the activity of sluggish tumor-suppressor genes.

7 Oct 2015

New capsule form of FMT raises hopes for treating C. difficile infection

A new capsule form of faecal microbiota transplantation (FMT) has raised hopes that this effective treatment for Clostridium difficile (C. difficile) infection and other bowel conditions might soon become mainstream. A recently-reported study confirmed that capsules containing a frozen suspension of faecal material harvested from healthy unrelated donors was well tolerated and effectively resolved diarrhoea in 90% of patients with difficult-to-treat C. difficile infection.

7 Oct 2015

Researchers study effect of immune tolerance on certain cancer risks

For a malignant tumor to form, cancer cells must evade the immune system's attack. Numerous studies have already shown that cancer spreads particularly aggressively if there is an unfavorable balance between suppressing and active immune cells in the tumor microenvironment. "But we didn't know whether this is a consequence of an aggressive tumor or rather its cause," says Rudolf Kaaks, epidemiologist at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ).

7 Oct 2015

Rabbit virus can be paired with existing drug to deliver more potent punch to brain tumor cells

A rabbit virus currently being developed for cancer therapy can be paired with one of several existing drugs to deliver a more potent punch to a deadly type of brain tumor cell, researchers have found.

7 Oct 2015

Quest Diagnostics provides PD-L1 IHC 22C3 PharmDx test service for NSCLC patients

Quest Diagnostics, the world’s leading provider of diagnostic information services, today announced that it will provide clinical laboratory testing using the PD-L1 IHC 22C3 PharmDx immunohistochemistry companion diagnostic.

From Quest Diagnostics 7 Oct 2015

Study describes new genome screen that identifies partner molecules of cell-waste disposal proteins

Rhythmic expression of key genes is essential for maintaining proper timekeeping of the body's clock. In addition, rhythmic degradation of clockwork proteins is also crucial. However, surprisingly, researchers know little about these specific processes.

7 Oct 2015

Binghamton University biochemist finds new way to fight cancer

A Binghamton University biochemist has discovered a new way to fight cancer, one that attacks only the cancer cells and promises fewer side effects. He hunts hedgehogs.

7 Oct 2015

NIH researchers discover why certain immune responses can be harmful to the brain

National Institutes of Health scientists studying inflammation of the brain have discovered why certain immune responses, which typically help cells recognize and fight viral and bacterial infections, can sometimes be harmful to the brain. Many brain disorders involve the death of neurons, or nerve cells, but how these neurons die is not well understood.

7 Oct 2015

NS1 protein can be considered as vital target for development of new drugs to treat dengue: Study

Dengue is a mosquito-borne tropical disease currently endemic in more than 10 countries. According to the World Health Organization, 390 million people are infected by dengue every year.

7 Oct 2015

Mutation that increases sphingolipid levels can lead to neurodegeneration

A mutation that increases the level of a special class of sphingolipids--molecules important to cell structure and signaling--can lead to neurodegeneration due to problems with neuronal membranes, reports a research team led by Jackson Laboratory Research Scientist Lihong Zhao, Ph.D. and Professor Patsy Nishina, Ph.D.

7 Oct 2015

Two researchers awarded NIH's New Innovator and Early Independence Awards

Two researchers, Martin Jonikas of Carnegie's Department of Plant Biology and Zhao Zhang of the Department of Embryology, have been awarded the New Innovator and Early Independence Awards, respectively, from the National Institutes of Health.

7 Oct 2015

CMOS camera removes noise from life science imaging

Photometrics, a manufacturer of high performance scientific cameras for life science applications, today announces the release of its new sCMOS camera, the Photometrics Prime. Prime is the first 4.2 Megapixel scientific CMOS camera available for life science research that actively defeats the negative impact of Poisson noise in low light images.

7 Oct 2015

Jumping genes: a marker for early cancer diagnosis? An interview with Dr Kazazian

In the genome of every human being, there are about 80-100 active LINE-1s that are capable of mobilizing by a copy and paste mechanism to a new location in the genome.

6 Oct 2015

Cabozantinib, nivolumab ‘bring hope’ for advanced RCC patients

Clinical trial results suggest significant benefits with the use of cabozantinib or nivolumab over everolimus for patients with advanced renal cell carcinoma, researchers reported at the European Cancer Congress in Vienna, Austria.

6 Oct 2015

T Cell News and Research

Latest T Cell News and Research

Lonza, Benitec partner to develop scalable manufacturing process for AAV-based viral gene therapies

SCT, Thermo Fisher Scientific collaborate to advance development of cardiac disease models

Penn Medicine announces $375,000 in new grants to support BRCA-focused research projects

Scientists awarded £417,000 to develop a gel to advance breast cancer research, reduce animal testing

Researchers describe unknown mechanism behind progeria

New book highlights sophisticated neurogenic processes in adult mammalian brain

New studies suggest ways to improve cancer care by inhibiting oncogenes, boosting tumor-suppressor activity

New capsule form of FMT raises hopes for treating C. difficile infection

Researchers study effect of immune tolerance on certain cancer risks

Rabbit virus can be paired with existing drug to deliver more potent punch to brain tumor cells

Quest Diagnostics provides PD-L1 IHC 22C3 PharmDx test service for NSCLC patients

Study describes new genome screen that identifies partner molecules of cell-waste disposal proteins

Binghamton University biochemist finds new way to fight cancer

NIH researchers discover why certain immune responses can be harmful to the brain

NS1 protein can be considered as vital target for development of new drugs to treat dengue: Study

Mutation that increases sphingolipid levels can lead to neurodegeneration

Two researchers awarded NIH's New Innovator and Early Independence Awards

CMOS camera removes noise from life science imaging

Jumping genes: a marker for early cancer diagnosis? An interview with Dr Kazazian

Cabozantinib, nivolumab ‘bring hope’ for advanced RCC patients

Immunology eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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